Publications by authors named "Uwe Warnken"

42Publications

SILAC-Based Quantification of TGFBR2-Regulated Protein Expression in Extracellular Vesicles of Microsatellite Unstable Colorectal Cancers.

Int J Mol Sci 2019 Aug 26;20(17). Epub 2019 Aug 26.

Department Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.

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August 2019

Deciphering the galectin-12 protein interactome reveals a major impact of galectin-12 on glutamine anaplerosis in colon cancer cells.

Exp Cell Res 2019 06 29;379(2):129-139. Epub 2019 Mar 29.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Germany; Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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June 2019

Synthetic phosphopeptides: From spike-in standards to affinity tools for protein-protein interaction studies.

Anal Biochem 2019 03 28;568:73-77. Epub 2018 Dec 28.

Functional Proteome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120, Heidelberg, Germany. Electronic address:

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March 2019

Detection of malignancy-associated phosphoproteome changes in human colorectal cancer induced by cell surface binding of growth-inhibitory galectin-4.

IUBMB Life 2019 03 14;71(3):364-375. Epub 2018 Dec 14.

Department of Applied Tumor Biology, Institute of Pathology, Medical School of the Ruprecht-Karls-University, Heidelberg, Germany.

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March 2019

Ataxia telangiectasia alters the ApoB and reelin pathway.

Neurogenetics 2018 12 21;19(4):237-255. Epub 2018 Oct 21.

Division for Neurology, Department for Children and Adolescents, Goethe University, 60590, Frankfurt am Main, Germany.

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December 2018

Two-Step Coimmunoprecipitation (TIP) Enables Efficient and Highly Selective Isolation of Native Protein Complexes.

Mol Cell Proteomics 2018 05 7;17(5):993-1009. Epub 2017 Dec 7.

From the ‡Department of Hematology and Oncology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy;

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May 2018

Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma.

Cell Stem Cell 2017 07 9;21(1):35-50.e9. Epub 2017 Jun 9.

Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; National Cancer Institute Regina Elena, 00144 Rome, Italy. Electronic address:

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July 2017

TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells.

Cell Commun Signal 2017 04 4;15(1):14. Epub 2017 Apr 4.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.

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April 2017

Deciphering the Acute Cellular Phosphoproteome Response to Irradiation with X-rays, Protons and Carbon Ions.

Mol Cell Proteomics 2017 05 16;16(5):855-872. Epub 2017 Mar 16.

From the ‡Functional Proteome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany;

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May 2017

Targeting Thioredoxin-1 by dimethyl fumarate induces ripoptosome-mediated cell death.

Sci Rep 2017 02 24;7:43168. Epub 2017 Feb 24.

Division of Immunogenetics, Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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February 2017

Detection of Proteome Changes in Human Colon Cancer Induced by Cell Surface Binding of Growth-Inhibitory Human Galectin-4 Using Quantitative SILAC-Based Proteomics.

J Proteome Res 2016 12 17;15(12):4412-4422. Epub 2016 Nov 17.

Department of Applied Tumor Biology, Institute of Pathology, Medical School of the Ruprecht-Karls-University , 69120 Heidelberg, Germany.

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December 2016

Identification of Novel Serum Autoantibodies for Differential Diagnosis of Autoimmune Pancreatitis and Pancreatic Ductal Adenocarcinoma.

Pancreas 2016 10;45(9):1309-19

From the *Department of General Surgery, University of Heidelberg, Heidelberg; †Department of Plant Biochemistry, Dahlem Centre of Plant Sciences, Freie Universität Berlin, Berlin; ‡Functional Proteome Analysis, German Cancer Research Center (DKFZ); and §Institute of Pathology, University of Heidelberg, Heidelberg and ∥Department of General-, Visceral-, Transplantations-, Vascular- and Thorax-Surgery, Ludwig Maximilian University of Munich, Munich, Germany.

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October 2016

A new method for detection of tumor driver-dependent changes of protein sialylation in a colon cancer cell line reveals nectin-3 as TGFBR2 target.

Protein Sci 2015 Oct 30;24(10):1686-94. Epub 2015 Jul 30.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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October 2015

Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells.

PLoS One 2015 26;10(6):e0131506. Epub 2015 Jun 26.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; Cancer Early Detection, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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May 2016

De Novo proteome analysis of genetically modified tumor cells by a metabolic labeling/azide-alkyne cycloaddition approach.

Mol Cell Proteomics 2014 Dec 15;13(12):3446-56. Epub 2014 Sep 15.

From the ‡Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, INF 224, 69120 Heidelberg, Germany; §Cancer Early Detection, German Cancer Research Center (DKFZ), INF 280, 69120 Heidelberg, Germany;

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December 2014

Serum protein signatures differentiating autoimmune pancreatitis versus pancreatic cancer.

PLoS One 2013 9;8(12):e82755. Epub 2013 Dec 9.

Department of General Surgery, University of Heidelberg, INF 110, Heidelberg, Germany.

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October 2014

In-depth mass spectrometric mapping of the human vitreous proteome.

Proteome Sci 2013 May 20;11(1):22. Epub 2013 May 20.

Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, Heidelberg, D-69120, Germany.

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May 2013

Quantification of High-Molecular Weight Protein Platforms by AQUA Mass Spectrometry as Exemplified for the CD95 Death-Inducing Signaling Complex (DISC).

Cells 2013 Jun 27;2(3):476-95. Epub 2013 Jun 27.

Department of Translational Inflammation Research, Institute of Experimental Internal Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.

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June 2013

Proteome of Hydra nematocyst.

J Biol Chem 2012 Mar 30;287(13):9672-81. Epub 2012 Jan 30.

Department of Molecular Evolution and Genomics, Centre for Organismal Studies, University of Heidelberg, Germany.

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March 2012

Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness.

Clin Cancer Res 2012 Jan 11;18(1):105-17. Epub 2011 Nov 11.

Clinical Cooperation Unit Neurooncology, German Cancer Research Center, University Hospital Heidelberg, Heidelberg, Germany.

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January 2012

Quantitative proteomics identify novel miR-155 target proteins.

PLoS One 2011 25;6(7):e22146. Epub 2011 Jul 25.

Functional Proteome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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December 2011

Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.

Life Sci 2011 Aug 6;89(9-10):304-12. Epub 2011 Jul 6.

Medizinische Universitätsklinik, Knappschaftskrankenhaus, IMBL, Ruhr-Universität Bochum, Bochum, Germany.

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August 2011

Subcellular protein extraction from human pancreatic cancer tissues.

Biotechniques 2009 Apr;46(4):297-304

Functional Genome Analysis, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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April 2009

The proteome of rat olfactory sensory cilia.

Proteomics 2009 Jan;9(2):322-34

Department of Molecular Physiology, Institute of Zoology, University of Heidelberg, Heidelberg, Germany.

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January 2009

Proteomic analysis of a membrane preparation from rat olfactory sensory cilia.

Chem Senses 2008 Feb 20;33(2):145-62. Epub 2007 Nov 20.

Department of Molecular Physiology, University of Heidelberg, Im Neuenheimer Feld 230, 69120 Heidelberg, Germany.

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February 2008

Sevoflurane degradation by carbon dioxide absorbents may produce more than one nephrotoxic compound in rats.

Can J Anaesth 2003 Mar;50(3):249-52

Department of Anesthesia and Perioperative Care, and the Department of Pathology, University of California, San Francisco 94143, USA.

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March 2003