Publications by authors named "Uwe J F Tietge"

100Publications

Triglycerides as target of cardiovascular risk reduction.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2021 Feb;32(1):76-77

Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet.

View Article and Find Full Text PDF
February 2021

Triglyceride/HDL cholesterol ratio and premature all-cause mortality in renal transplant recipients.

Nephrol Dial Transplant 2020 Dec 12. Epub 2020 Dec 12.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
December 2020

HDL Cholesterol Efflux Capacity is Impaired in Severe Short-Term Hypothyroidism Despite Increased HDL Cholesterol.

J Clin Endocrinol Metab 2020 Sep;105(9)

Department of Endocrinology, University of Groningen, University Medical Center Groningen, RB Groningen, The Netherlands.

View Article and Find Full Text PDF
September 2020

Statin Use Is Prospectively Associated With New-Onset Diabetes After Transplantation in Renal Transplant Recipients.

Diabetes Care 2020 08 22;43(8):1945-1947. Epub 2020 May 22.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

View Article and Find Full Text PDF
August 2020

Dietary Isomalto/Malto-Polysaccharides Increase Fecal Bulk and Microbial Fermentation in Mice.

Mol Nutr Food Res 2020 06 13;64(12):e2000251. Epub 2020 May 13.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, The Netherlands.

View Article and Find Full Text PDF
June 2020

Long-Term β-galacto-oligosaccharides Supplementation Decreases the Development of Obesity and Insulin Resistance in Mice Fed a Western-Type Diet.

Mol Nutr Food Res 2020 06 25;64(12):e1900922. Epub 2020 May 25.

Department of Pediatrics , University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, The Netherlands.

View Article and Find Full Text PDF
June 2020

Group IIA Secretory Phospholipase A Predicts Graft Failure and Mortality in Renal Transplant Recipients by Mediating Decreased Kidney Function.

J Clin Med 2020 Apr 29;9(5). Epub 2020 Apr 29.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

View Article and Find Full Text PDF
April 2020

The anti-inflammatory function of follicular fluid HDL and outcome of modified natural cycle in vitro fertilization†.

Biol Reprod 2020 06;103(1):7-9

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2020

Editorial: Clonal hematopoiesis: a link between inflammation, ageing and cardiovascular disease.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2020 04;31(2):102-103

Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet.

View Article and Find Full Text PDF
April 2020

Gestational oxidative stress protects against adult obesity and insulin resistance.

Redox Biol 2020 01 17;28:101329. Epub 2019 Sep 17.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, the Netherlands; Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Alfred Nobels Alle 8, Stockholm, Sweden; Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

View Article and Find Full Text PDF
January 2020

Anti-oxidative function of follicular fluid HDL and outcomes of modified natural cycle-IVF.

Sci Rep 2019 09 6;9(1):12817. Epub 2019 Sep 6.

Department of Paediatrics, Centre for Liver, Digestive, and Metabolic Diseases, University of Groningen, University Medical Centre Groningen, 9713 GZ, Groningen, The Netherlands.

View Article and Find Full Text PDF
September 2019

HDL Cholesterol Efflux Predicts Incident New-Onset Diabetes After Transplantation (NODAT) in Renal Transplant Recipients Independent of HDL Cholesterol Levels.

Diabetes 2019 10 2;68(10):1915-1923. Epub 2019 Aug 2.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

View Article and Find Full Text PDF
October 2019

The Origin of Follicular Bile Acids in the Human Ovary.

Am J Pathol 2019 10 29;189(10):2036-2045. Epub 2019 Jul 29.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

View Article and Find Full Text PDF
October 2019

HDL (High-Density Lipoprotein) Cholesterol Efflux Capacity Is Associated With Incident Cardiovascular Disease in the General Population.

Arterioscler Thromb Vasc Biol 2019 09 18;39(9):1874-1883. Epub 2019 Jul 18.

From the Department of Pediatrics (S.E., U.J.F.T.), University of Groningen, University Medical Center Groningen, the Netherlands.

View Article and Find Full Text PDF
September 2019

Preconceptional Maternal Bile Acids and Birth Weight of Neonates.

Hepatol Commun 2019 Jun 28;3(6):849-850. Epub 2019 Mar 28.

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases University of Groningen, University Medical Center Groningen Groningen the Netherlands.

View Article and Find Full Text PDF
June 2019

An evolutionary look at cholesterol.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2019 02;30(1):48-49

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
February 2019

Absence of Intestinal Microbiota during Gestation and Lactation Does Not Alter the Metabolic Response to a Western-type Diet in Adulthood.

Mol Nutr Food Res 2019 02 5;63(3):e1800809. Epub 2018 Dec 5.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, 9700 RB, Groningen, The Netherlands.

View Article and Find Full Text PDF
February 2019

Effect of the prebiotic fiber inulin on cholesterol metabolism in wildtype mice.

Sci Rep 2018 09 5;8(1):13238. Epub 2018 Sep 5.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
September 2018

Anti-tumor necrosis factor-α therapy increases plaque burden in a mouse model of experimental atherosclerosis.

Atherosclerosis 2018 10 27;277:80-89. Epub 2018 Aug 27.

Cardiology and Angiology, Philipps-University Marburg, Marburg, Germany. Electronic address:

View Article and Find Full Text PDF
October 2018

Cholesterol efflux capacity is impaired in subjects with an elevated Fatty Liver Index, a proxy of non-alcoholic fatty liver disease.

Atherosclerosis 2018 10 27;277:21-27. Epub 2018 Jul 27.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands. Electronic address:

View Article and Find Full Text PDF
October 2018

Milk cholesterol concentration in mice is not affected by high cholesterol diet- or genetically-induced hypercholesterolaemia.

Sci Rep 2018 06 11;8(1):8824. Epub 2018 Jun 11.

Department of Pediatrics, Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2018

PURE and simple? A new perspective on the impact of diet on hyperlipidemia and cardiovascular risk.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2018 06;29(3):273-274

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2018

The HDL anti-inflammatory function is impaired in the context of low-normal free thyroxine in diabetic and nondiabetic individuals.

Clin Endocrinol (Oxf) 2018 05 12;88(5):752-754. Epub 2018 Mar 12.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2018

The impact of myeloperoxidase on HDL function in myocardial infarction.

Authors:
Uwe J F Tietge

Curr Opin Endocrinol Diabetes Obes 2018 04;25(2):137-142

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
April 2018

The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation.

Cardiovasc Diabetol 2017 10 12;16(1):132. Epub 2017 Oct 12.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.

View Article and Find Full Text PDF
October 2017

ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.

Arterioscler Thromb Vasc Biol 2017 11 7;37(11):2147-2155. Epub 2017 Sep 7.

From the Translational Laboratory in Genetic Medicine, A*STAR Institute, and Yong Loo Lin School of Medicine, National University of Singapore (L.T.-M., D.C., E.C.C., L.J.T., D.H.W., G.K.Y., M.R.H., R.R.S.); Departments of Vascular Medicine and Experimental Vascular Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands (J.C.v.C., A.W.M.S., G.M.D.-T., G.K.H.); Faculty of Health Sciences, Simon Fraser University, Canada (I.T.); Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore (F.T., P.N., M.R.W.); Centre for Molecular Medicine and Therapeutics and Child and Family Research Institute, University of British Columbia, Canada (L.-H.Z., M.K., M.R.H.); Department of Pediatrics, University Medical Center Groningen, University of Groningen, The Netherlands (L.G.D., U.J.F.T.); Xenon Pharmaceuticals, Burnaby, Canada (I.T., C.R.); Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore (C.H.T., V.A.); Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Austria (F.D., J.B.); Beaulieu-Saucier Université de Montréal Pharmacogenomics Centre, Canada (A.B., M.-P.D.); Montréal Heart Institute Research Centre, Canada (A.B., M.-P.D.); and Université de Montréal, Canada (A.B., M.-P.D.).

View Article and Find Full Text PDF
November 2017

Downregulation of cholesteryl ester transfer protein by glucocorticoids: a randomised study on HDL.

Eur J Clin Invest 2017 Jul 14;47(7):494-503. Epub 2017 Jun 14.

Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

View Article and Find Full Text PDF
July 2017

Inhibiting Cholesterol Absorption During Lactation Programs Future Intestinal Absorption of Cholesterol in Adult Mice.

Gastroenterology 2017 08 22;153(2):382-385.e3. Epub 2017 Apr 22.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article and Find Full Text PDF
August 2017

High-cholesterol diet does not alter gut microbiota composition in mice.

Nutr Metab (Lond) 2017 16;14:15. Epub 2017 Feb 16.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
February 2017

Transintestinal and Biliary Cholesterol Secretion Both Contribute to Macrophage Reverse Cholesterol Transport in Rats-Brief Report.

Arterioscler Thromb Vasc Biol 2017 04 23;37(4):643-646. Epub 2017 Feb 23.

From the Departments of Pediatrics (J.F.d.B., M.S., A.D., M.K., R.H., F.K., U.J.F.T., A.K.G.) and Laboratory Medicine (F.K., A.K.G.), University of Groningen, University Medical Center Groningen, The Netherlands.

View Article and Find Full Text PDF
April 2017

High density lipoprotein (HDL) particles from end-stage renal disease patients are defective in promoting reverse cholesterol transport.

Sci Rep 2017 02 2;7:41481. Epub 2017 Feb 2.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
February 2017

Absence of intestinal microbiota increases ß-cyclodextrin stimulated reverse cholesterol transport.

Mol Nutr Food Res 2017 05 22;61(5). Epub 2017 Feb 22.

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2017

Reverse Cholesterol Transport Is Increased in Germ-Free Mice-Brief Report.

Arterioscler Thromb Vasc Biol 2017 Mar 5;37(3):419-422. Epub 2017 Jan 5.

From the Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University of Groningen, University Medical Center Groningen, The Netherlands.

View Article and Find Full Text PDF
March 2017

'Examine my kidneys and my heart': linking renal and cardiovascular disease.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2017 02;28(1):83-84

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
February 2017

HDL function is impaired in acute myocardial infarction independent of plasma HDL cholesterol levels.

J Clin Lipidol 2016 Nov - Dec;10(6):1318-1328. Epub 2016 Aug 17.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Top Institute Food and Nutrition, Wageningen, The Netherlands. Electronic address:

View Article and Find Full Text PDF
October 2017

Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity.

Mediators Inflamm 2016 6;2016:2042107. Epub 2016 Jun 6.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, Netherlands; Top Institute Food and Nutrition, 6709 AN Wageningen, Netherlands.

View Article and Find Full Text PDF
May 2017

Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice.

J Lipid Res 2016 08 16;57(8):1455-64. Epub 2016 Jun 16.

Department of Pediatrics University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Department of Laboratory Medicine, Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Amsterdam Diabetes Center, Department of Vascular Medicine, Academic Medical Center, The Netherlands.

View Article and Find Full Text PDF
August 2016

The predictive value of the antioxidative function of HDL for cardiovascular disease and graft failure in renal transplant recipients.

Atherosclerosis 2016 06 8;249:181-5. Epub 2016 Apr 8.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands. Electronic address:

View Article and Find Full Text PDF
June 2016

Impaired Cholesterol Efflux Capacity of High-Density Lipoprotein Isolated From Interstitial Fluid in Type 2 Diabetes Mellitus-Brief Report.

Arterioscler Thromb Vasc Biol 2016 05 31;36(5):787-91. Epub 2016 Mar 31.

From the Metabolism Unit (J.A., P.P., B.A., M.R.) and KI/AZ Integrated CardioMetabolic Center (J.A., B.A., M.R.), Department of Medicine and Department of Biosciences and Nutrition (J.A., B.A., M.R.), Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden. Department of Pediatrics, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands (U.J.F.T., A.D.); and Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institute at Karolinska University Hospital Huddinge, Stockholm, Sweden (P.P.).

View Article and Find Full Text PDF
May 2016

Cholesterol-absorbed in thought.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2016 Apr;27(2):202-3

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
April 2016

Obesity-induced chronic inflammation in high fat diet challenged C57BL/6J mice is associated with acceleration of age-dependent renal amyloidosis.

Sci Rep 2015 Nov 13;5:16474. Epub 2015 Nov 13.

Department of Pathology &Medical Biology, Medical Biology Section, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
November 2015

Hepatic ABCG5/G8 overexpression substantially increases biliary cholesterol secretion but does not impact in vivo macrophage-to-feces RCT.

Atherosclerosis 2015 Dec 8;243(2):402-6. Epub 2015 Oct 8.

Department of Pediatrics, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article and Find Full Text PDF
December 2015

HDL Cholesterol Efflux Predicts Graft Failure in Renal Transplant Recipients.

J Am Soc Nephrol 2016 Feb 28;27(2):595-603. Epub 2015 Aug 28.

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Top Institute Food and Nutrition, Wageningen, The Netherlands;

View Article and Find Full Text PDF
February 2016

Acute perioperative-stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition.

Dis Model Mech 2015 Sep 18;8(9):1071-80. Epub 2015 Jun 18.

Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, 30625 Hannover, Germany Faculty VI - Medicine and Health Sciences, Dept of Health Services Sciences, University of Oldenburg, 26129 Germany

View Article and Find Full Text PDF
September 2015

Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport.

Cardiovasc Res 2015 May 13;106(2):314-23. Epub 2015 Mar 13.

INSERM, UMR 1048, Institut de Maladies Métaboliques et Cardiovasculaires, Toulouse, France Université de Toulouse III, UMR 1048, Toulouse, France CHU de Toulouse, Hôpital Purpan, Toulouse, France INSERM U1048, Bât. L3, Hôpital Rangueil, BP 84225, 31432 Toulouse cedex 04, France

View Article and Find Full Text PDF
May 2015

HDL - Hope Dies Last?

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2015 Apr;26(2):150-1

Department of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
April 2015

Cholesterol efflux and reverse cholesterol transport.

Handb Exp Pharmacol 2015 ;224:181-206

Department of Pharmacy, University of Parma, Parco Area delle Scienze 27/A, 43124, Parma, Italy.

View Article and Find Full Text PDF
April 2015

A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation.

FASEB J 2015 Apr 4;29(4):1153-64. Epub 2014 Dec 4.

Departments of *Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands; Netherlands Consortium for Systems Biology, University of Amsterdam, Amsterdam, The Netherlands; Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands; and Groningen Centre for Systems Biology, University of Groningen, Groningen, The Netherlands

View Article and Find Full Text PDF
April 2015

Mitogen-activated protein kinase-activated protein kinase 2 deficiency reduces insulin sensitivity in high-fat diet-fed mice.

PLoS One 2014 18;9(9):e106300. Epub 2014 Sep 18.

Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2015

Impact of maternal cholesterol metabolism on ovarian follicle development and fertility.

J Reprod Immunol 2014 Oct 14;104-105:32-6. Epub 2014 May 14.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
October 2014

Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport.

J Hepatol 2014 Aug 26;61(2):351-7. Epub 2014 Mar 26.

University of Groningen, University Medical Center Groningen, Department of Pediatrics, Groningen, The Netherlands; Department of Laboratory Medicine, Groningen, The Netherlands.

View Article and Find Full Text PDF
August 2014

Alterations in plasma lecithin:cholesterol acyltransferase and myeloperoxidase in acute myocardial infarction: implications for cardiac outcome.

Atherosclerosis 2014 May 11;234(1):185-92. Epub 2014 Mar 11.

Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2014

The HDL anti-inflammatory function is impaired in myocardial infarction and may predict new cardiac events independent of HDL cholesterol.

Clin Chim Acta 2014 Jun 5;433:34-8. Epub 2014 Mar 5.

Department of Pediatrics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2014

Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice.

J Lipid Res 2014 May 7;55(5):816-25. Epub 2014 Feb 7.

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2014

Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.

PLoS One 2014 22;9(1):e86404. Epub 2014 Jan 22.

Division of Endocrinology, Diabetes and Hypertension, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America.

View Article and Find Full Text PDF
November 2014

Hyperlipidemia and cardiovascular disease: inflammation, dyslipidemia, and atherosclerosis.

Authors:
Uwe J F Tietge

Curr Opin Lipidol 2014 Feb;25(1):94-5

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

View Article and Find Full Text PDF
February 2014

Simvastatin and bezafibrate increase cholesterol efflux in men with type 2 diabetes.

Eur J Clin Invest 2014 6;44(3):240-8. Epub 2014 Jan 6.

Department of Endocrinology, Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

View Article and Find Full Text PDF
October 2014

Expression of type IIA secretory phospholipase A2 inhibits cholesteryl ester transfer protein activity in transgenic mice.

Arterioscler Thromb Vasc Biol 2013 Dec 10;33(12):2707-14. Epub 2013 Oct 10.

From the Department of Bioscience, CVMD iMED, AstraZeneca, R&D, Mölndal, Sweden (E.H.-C., B.R., M.B.); Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands (T.G., A.D., U.J.F.T.); INSERM UMR866, Faculté de Médecine, Université de Bourgogne, Dijon, France (T.G.); Taconic, Hudson, NY (D.S.G.); and Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia (D.J.R.).

View Article and Find Full Text PDF
December 2013

Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis.

Biochim Biophys Acta 2013 Dec 28;1832(12):1922-9. Epub 2013 Jun 28.

Dept. of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article and Find Full Text PDF
December 2013

Assessing the functional properties of high-density lipoproteins: an emerging concept in cardiovascular research.

Biomark Med 2013 Jun;7(3):457-72

Department of Pediatrics, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2013

rHDL administration increases reverse cholesterol transport in mice, but is not additive on top of ezetimibe or cholestyramine treatment.

Atherosclerosis 2013 Jul 10;229(1):94-101. Epub 2013 May 10.

F. Hoffmann La Roche Ltd. pRED, Cardiovascular & Metabolic Diseases, Basel, Switzerland.

View Article and Find Full Text PDF
July 2013

The inverse relation of HDL anti-oxidative functionality with serum amyloid a is lost in metabolic syndrome subjects.

Obesity (Silver Spring) 2013 Feb;21(2):361-6

Department of Endocrinology, Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen and University of Groningen, Groningen.

View Article and Find Full Text PDF
February 2013

Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice.

Hepatology 2013 Jul 14;58(1):293-303. Epub 2013 May 14.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, the Netherlands.

View Article and Find Full Text PDF
July 2013

Low normal free T4 confers decreased high-density lipoprotein antioxidative functionality in the context of hyperglycaemia.

Clin Endocrinol (Oxf) 2013 Sep 11;79(3):416-23. Epub 2013 May 11.

Department of Endocrinology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
September 2013

Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis.

Clin Nutr 2013 Feb 6;32(1):122-9. Epub 2012 Jul 6.

Charité - Universitätsmedizin Berlin, Department of Gastroenterology, Infectiology and Rheumatology (incl. section on Clinical Nutrition), Charitéplatz 1, Berlin 10117, Germany.

View Article and Find Full Text PDF
February 2013

Pancreatic β-cell function relates positively to HDL functionality in well-controlled type 2 diabetes mellitus.

Atherosclerosis 2012 Jun 11;222(2):567-73. Epub 2012 Apr 11.

Department of Endocrinology, Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2012

ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma.

J Lipid Res 2012 May 1;53(5):929-40. Epub 2012 Mar 1.

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2012

High-density lipoprotein loses its anti-inflammatory capacity by accumulation of pro-inflammatory-serum amyloid A.

Cardiovasc Res 2012 Apr 10;94(1):154-62. Epub 2012 Feb 10.

Med. Klinik mit - SP Nephrologie, Charité - Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.

View Article and Find Full Text PDF
April 2012

Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice.

J Lipid Res 2012 Mar 18;53(3):348-57. Epub 2011 Dec 18.

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University Medical Center Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
March 2012

Plasma bile acids are associated with energy expenditure and thyroid function in humans.

J Clin Endocrinol Metab 2012 Feb 7;97(2):535-42. Epub 2011 Dec 7.

Department of Gastroenterology, Hepatology, Endocrinology, and Nutrition, Klinikum Bremen Mitte, St. Juergen Strasse 1, D-28177 Bremen, Germany.

View Article and Find Full Text PDF
February 2012

Activated platelets contribute to oxidized low-density lipoproteins and dysfunctional high-density lipoproteins through a phospholipase A2-dependent mechanism.

FASEB J 2012 Feb 31;26(2):927-37. Epub 2011 Oct 31.

Institut National de la Santé et de la Recherche Médicale (INSERM)/Université de Bourgogne, Lipids, Nutrition, Cancer, Faculté de Médecine, Dijon, France.

View Article and Find Full Text PDF
February 2012

Increased LCAT activity and hyperglycaemia decrease the antioxidative functionality of HDL.

Eur J Clin Invest 2012 May 28;42(5):487-95. Epub 2011 Sep 28.

Department of Endocrinology, Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2012

Skin autofluorescence is inversely related to HDL anti-oxidative capacity in type 2 diabetes mellitus.

Atherosclerosis 2011 Sep 18;218(1):102-6. Epub 2011 May 18.

Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
September 2011

Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport.

Curr Atheroscler Rep 2011 Jun;13(3):257-65

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2011

Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI: role of negatively charged phospholipids.

Atherosclerosis 2011 Apr 19;215(2):374-82. Epub 2011 Jan 19.

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University Hospital Muenster, Muenster, Germany.

View Article and Find Full Text PDF
April 2011

Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice.

Biochim Biophys Acta 2011 Apr 3;1811(4):294-9. Epub 2011 Feb 3.

Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
April 2011