Uwe Heinemann

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Uwe Heinemann

Publications by authors named "Uwe Heinemann"

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99Publications

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Event-Associated Oxygen Consumption Rate Increases ca. Five-Fold When Interictal Activity Transforms into Seizure-Like Events In Vitro.

Int J Mol Sci 2017 Sep 7;18(9). Epub 2017 Sep 7.

Neuroscience Research Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.

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September 2017

Contribution of Intrinsic Lactate to Maintenance of Seizure Activity in Neocortical Slices from Patients with Temporal Lobe Epilepsy and in Rat Entorhinal Cortex.

Int J Mol Sci 2017 08 23;18(9). Epub 2017 Aug 23.

Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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August 2017

Epileptiform activity and spreading depolarization in the blood-brain barrier-disrupted peri-infarct hippocampus are associated with impaired GABAergic inhibition and synaptic plasticity.

J Cereb Blood Flow Metab 2017 May 1;37(5):1803-1819. Epub 2016 Jan 1.

3 Departments of Physiology and Cell Biology, Cognitive and Brain Sciences, The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

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May 2017

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.

J Cereb Blood Flow Metab 2017 May 1;37(5):1595-1625. Epub 2016 Jan 1.

23 Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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May 2017

The hippocampus influences assimilation and accommodation of schemata that are not hippocampus-dependent.

Hippocampus 2017 Mar 16;27(3):315-331. Epub 2017 Jan 16.

Neuroscience Research Center, Charité Universitätsmedizin, Berlin, Germany.

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March 2017

Neurobiological consequences of juvenile stress: A GABAergic perspective on risk and resilience.

Neurosci Biobehav Rev 2017 03 11;74(Pt A):21-43. Epub 2017 Jan 11.

Sagol Department of Neurobiology, University of Haifa, 199 Aba-Hushi Avenue, 3498838 Haifa, Israel; The Institute for the Study of Affective Neuroscience (ISAN), 199 Aba-Hushi Avenue, 3498838 Haifa, Israel; Department of Psychology, University of Haifa, 199 Aba-Hushi Avenue, 3498838 Haifa, Israel.

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March 2017

Pretreatment with β-adrenergic receptor agonists facilitates induction of LTP and sharp wave ripple complexes in rodent hippocampus.

Hippocampus 2016 12 18;26(12):1486-1492. Epub 2016 Oct 18.

Neuroscience Research Center, Charite Universitatsmedizin Berlin, Germany.

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December 2016

A neuronal lactate uptake inhibitor slows recovery of extracellular ion concentration changes in the hippocampal CA3 region by affecting energy metabolism.

J Neurophysiol 2016 Nov 24;116(5):2420-2430. Epub 2016 Aug 24.

Neuroscience Research Center, Charité Universitätsmedizin, Berlin, Germany;

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November 2016

WONOEP appraisal: Molecular and cellular biomarkers for epilepsy.

Epilepsia 2016 09 4;57(9):1354-62. Epub 2016 Jul 4.

Department of Pharmaceutical Science, University of Colorado, Aurora, Colorado, U.S.A.

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September 2016

Long-term changes in the CA3 associative network of fear-conditioned mice.

Stress 2015 30;18(2):188-97. Epub 2015 Jan 30.

Department of Genetics & Molecular Neurobiology, Institute of Biology, Otto-von-Guericke-University Magdeburg , Magdeburg , Germany .

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July 2016

Synaptic plasticity in area CA1 of rat hippocampal slices following intraventricular application of albumin.

Neurobiol Dis 2016 07 10;91:155-65. Epub 2016 Mar 10.

Neuroscience Research Center and Institute of Neurophysiology, Charite-University Medicine Berlin, Berlin, Germany. Electronic address:

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July 2016

Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence.

Cereb Cortex 2016 May 22;26(5):2325-2340. Epub 2016 Feb 22.

Division Cell Physiology, Zoological Institute, Braunschweig 38106, Germany.

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May 2016

Hierarchical spike clustering analysis for investigation of interneuron heterogeneity.

Neurosci Lett 2016 Apr 14;619:86-91. Epub 2016 Mar 14.

Institute of Cellular Neurosciences, University of Bonn Medical School, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; Institute of Neurology, University College London, London, United Kingdom. Electronic address:

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April 2016

In vitro seizure like events and changes in ionic concentration.

J Neurosci Methods 2016 Feb 21;260:33-44. Epub 2015 Aug 21.

Institute of Neurophysiology and Neuroscience Research Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, D 10117 Berlin, Germany. Electronic address:

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February 2016

Serotonin dependent masking of hippocampal sharp wave ripples.

Neuropharmacology 2016 Feb 26;101:188-203. Epub 2015 Sep 26.

Inst. Neurophysiology, Charité Universitätsmedizin, Berlin, Germany; Neuroscience Research Center, Charité Universitätsmedizin, Berlin, Germany. Electronic address:

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February 2016

Differential participation of pyramidal cells in generation of spontaneous sharp wave-ripples in the mouse subiculum in vitro.

Neurobiol Learn Mem 2015 Nov 28;125:113-9. Epub 2015 Aug 28.

Neuroscience Research Center and Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

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November 2015

Widespread activation of microglial cells in the hippocampus of chronic epileptic rats correlates only partially with neurodegeneration.

Brain Struct Funct 2015 Jul 31;220(4):2423-39. Epub 2014 May 31.

Institute of Physiology and Pathophysiology, University of Heidelberg, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.

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July 2015

Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3.

Eur J Neurosci 2015 Jul 12;42(2):1808-17. Epub 2015 Jun 12.

Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.

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July 2015

WONOEP appraisal: molecular and cellular imaging in epilepsy.

Epilepsia 2015 Apr 28;56(4):505-13. Epub 2015 Feb 28.

Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, U.S.A; Harvard Medical School, Boston, Massachusetts, U.S.A.

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April 2015

State-dependencies of learning across brain scales.

Front Comput Neurosci 2015 26;9. Epub 2015 Feb 26.

Bernstein Center for Computational Neuroscience, Humboldt-Universität zu Berlin Berlin, Germany ; Department of Biology, Institute for Theoretical Biology (ITB), Humboldt-Universität zu Berlin Berlin, Germany.

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March 2015

The blood-brain barrier-gatekeeper to neuronal homeostasis: clinical implications in the setting of stroke.

Semin Cell Dev Biol 2015 Feb 7;38:35-42. Epub 2014 Nov 7.

Institute for Neurophysiology, Charité - University Medicine Berlin, Germany. Electronic address:

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February 2015

Corticosterone and corticotropin-releasing factor acutely facilitate gamma oscillations in the hippocampus in vitro.

Eur J Neurosci 2015 Jan 13;41(1):31-44. Epub 2014 Oct 13.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117, Berlin, Germany.

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January 2015

Should losartan be administered following brain injury?

Expert Rev Neurother 2014 Dec 27;14(12):1365-75. Epub 2014 Oct 27.

Department of Medical Neuroscience, Faculty of Medicine, Dalhousie University, PO Box 15000, 5850 College Street, Halifax Nova Scotia B3H 4R2, Canada.

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December 2014

What is the clinical relevance of in vitro epileptiform activity?

Adv Exp Med Biol 2014 ;813:25-41

Neuroscience Research Center, Charité Universitätsmedizin Berlin, Garystr. 5, D 14195, Berlin, Germany,

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November 2014

Monitoring stroke progression: in vivo imaging of cortical perfusion, blood-brain barrier permeability and cellular damage in the rat photothrombosis model.

J Cereb Blood Flow Metab 2014 Nov 27;34(11):1791-801. Epub 2014 Aug 27.

1] Departments of Physiology and Cell Biology, Cognitive and Brain Sciences, The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel [2] Department of Medical Neuroscience, Faculty of Medicine, Dalhousie University, Halifax, Canada.

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November 2014

5-HT4-receptors modulate induction of long-term depression but not potentiation at hippocampal output synapses in acute rat brain slices.

PLoS One 2014 5;9(2):e88085. Epub 2014 Feb 5.

Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Berlin, Germany ; Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Berlin, Berlin, Germany ; Department of Psychiatry, Psychotherapy and Psychosomatics, Ruppiner Kliniken, Neuruppin, Brandenburg, Germany.

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September 2014

Blood-brain barrier dysfunction can contribute to pharmacoresistance of seizures.

Epilepsia 2014 Aug 3;55(8):1255-63. Epub 2014 Jul 3.

Institute of Neurophysiology, Charite-University Medicine Berlin, Berlin, Germany.

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August 2014

Losartan prevents acquired epilepsy via TGF-β signaling suppression.

Ann Neurol 2014 Jun 28;75(6):864-75. Epub 2014 May 28.

Departments of Physiology and Cell Biology, Cognitive and Brain Sciences, Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

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June 2014

GABAB receptor dependent modulation of sharp wave-ripple complexes in the rat hippocampus in vitro.

Neurosci Lett 2014 Jun 4;574:15-20. Epub 2014 May 4.

Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, 14195 Berlin, Germany; NeuroCure Research Center, Charité-Universitätsmedizin Berlin, 14195 Berlin, Germany. Electronic address:

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June 2014

Increased susceptibility to acetylcholine in the entorhinal cortex of pilocarpine-treated rats involves alterations in KCNQ channels.

Neurobiol Dis 2013 Aug 11;56:14-24. Epub 2013 Apr 11.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Charitéplatz 1, D 10117 Berlin, Germany.

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August 2013

Network activity in hippocampal slice cultures revealed by long-term in vitro recordings.

J Neurosci Methods 2013 Jul 29;217(1-2):1-8. Epub 2013 Apr 29.

Institute of Neurophysiology, Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany.

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July 2013

Activity-dependent changes in extracellular Ca2+ and K+ reveal pacemakers in the spinal locomotor-related network.

Neuron 2013 Mar;77(6):1047-54

Team P3M, Institut de Neurosciences de la Timone, UMR 7289, CNRS and Aix-Marseille Université, F-13385 Marseille, France.

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March 2013

Long-lasting increase of corticosterone after fear memory reactivation: anxiolytic effects and network activity modulation in the ventral hippocampus.

Neuropsychopharmacology 2013 Feb 12;38(3):386-94. Epub 2012 Sep 12.

Institute of Biology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

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February 2013

Contribution of near-threshold currents to intrinsic oscillatory activity in rat medial entorhinal cortex layer II stellate cells.

J Neurophysiol 2013 Jan 17;109(2):445-63. Epub 2012 Oct 17.

Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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January 2013

A LED-based method for monitoring NAD(P)H and FAD fluorescence in cell cultures and brain slices.

J Neurosci Methods 2013 Jan 8;212(2):222-7. Epub 2012 Nov 8.

Neuroscience Research Center, Charité-Universitätsmedizin Berlin, Germany.

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January 2013

First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors.

Br J Pharmacol 2012 Dec;167(7):1480-91

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Berlin, Germany NeuroCure Research Centre, Charité Universitätsmedizin Berlin, Berlin, Germany.

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December 2012

Differential effects of blockade of ERG channels on gamma oscillations and excitability in rat hippocampal slices.

Eur J Neurosci 2012 Dec 10;36(12):3628-35. Epub 2012 Oct 10.

Institute for Neurophysiology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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December 2012

Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling.

J Cell Mol Med 2012 Nov;16(11):2736-44

Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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November 2012

Primary afterdischarge in organotypic hippocampal slice cultures: effects of standard antiepileptic drugs.

Epilepsia 2012 Nov 19;53(11):1928-36. Epub 2012 Jul 19.

Institute of Neurophysiology, Charite University Medicine Berlin, Oudenarderstrasse 16, Berlin, Germany.

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November 2012

Energy demand of synaptic transmission at the hippocampal Schaffer-collateral synapse.

J Cereb Blood Flow Metab 2012 Nov 29;32(11):2076-83. Epub 2012 Aug 29.

Institute for Neurophysiology, Charité-Universitätsmedizin, Berlin, Germany.

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November 2012

Extracellular ATP differentially affects epileptiform activity via purinergic P2X7 and adenosine A1 receptors in naive and chronic epileptic rats.

Epilepsia 2012 Nov 25;53(11):1978-86. Epub 2012 Oct 25.

Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, Charitplatz 1, Berlin, Germany.

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November 2012

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: role of astroglia.

Epilepsia 2012 Nov;53 Suppl 6:53-9

Institute for Neurophysiology, Charité-Medical University Berlin, Berlin, Germany.

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November 2012

Blood-brain barrier dysfunction in epileptogenesis of the temporal lobe.

Epilepsy Res Treat 2011 7;2011:143908. Epub 2011 Jun 7.

Departments of Physiology and Neurobiology, Ben-Gurion University of the Negev, Beersheva 84105, Israel.

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August 2012

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy.

Glia 2012 Aug 29;60(8):1251-7. Epub 2012 Feb 29.

Institute of Neurophysiology, Charité Universitätsmedizin, Berlin.

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August 2012

Reduced ictogenic potential of 4-aminopyridine in the hippocampal region in the pilocarpine model of epilepsy.

Neurosci Lett 2012 Apr 9;513(2):124-8. Epub 2012 Feb 9.

Charité - Universitätsmedizin Berlin, Institute for Neurophysiology, Germany.

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April 2012

Purinergic P2X, P2Y and adenosine receptors differentially modulate hippocampal gamma oscillations.

Neuropharmacology 2012 Feb 8;62(2):914-24. Epub 2011 Oct 8.

Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, Oudenarder Str. 16, D-13347 Berlin, Germany.

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February 2012

High-frequency stimulation of the temporoammonic pathway induces input-specific long-term potentiation in subicular bursting cells.

Brain Res 2012 Jan 31;1430:1-7. Epub 2011 Oct 31.

Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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January 2012

Heterogeneous voltage dependence of interneuron resonance in the hippocampal stratum radiatum of adult rats.

Synapse 2011 Dec 31;65(12):1378-81. Epub 2011 Aug 31.

Institute of Neurophysiology, Charité, Berlin 13347, Germany.

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December 2011

Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats.

Glia 2011 Nov 20;59(11):1706-18. Epub 2011 Jul 20.

Institute for Neurophysiology and NeuroCure Research Center, Charité-Universitätsmedizin, Berlin, Germany.

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November 2011

Functional test of multidrug transporter activity in hippocampal-neocortical brain slices from epileptic patients.

J Neurosci Methods 2011 Sep 7;200(2):164-72. Epub 2011 Jul 7.

Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.

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September 2011

Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus.

Neuroreport 2011 Aug;22(11):520-4

Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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August 2011

Low-frequency stimulation of the temporoammonic pathway induces heterosynaptic disinhibition in the subiculum.

Hippocampus 2011 Jul 13;21(7):733-43. Epub 2010 Apr 13.

Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Charitéplatz, Berlin, Germany.

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July 2011

Slice cultures as a model to study neurovascular coupling and blood brain barrier in vitro.

Cardiovasc Psychiatry Neurol 2011 16;2011:646958. Epub 2011 Feb 16.

Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, Oudenarder Strasse 16, 13347 Berlin, Germany.

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July 2011

Impact of aquaporin-4 channels on K+ buffering and gap junction coupling in the hippocampus.

Glia 2011 Jun 28;59(6):973-80. Epub 2011 Mar 28.

Institute of Cellular Neurosciences, University of Bonn, Bonn, Germany.

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June 2011

RNA editing of Kv1.1 channels may account for reduced ictogenic potential of 4-aminopyridine in chronic epileptic rats.

Epilepsia 2011 Mar 3;52(3):645-8. Epub 2011 Mar 3.

Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, Marburg, Germany.

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March 2011

Partial disinhibition is required for transition of stimulus-induced sharp wave-ripple complexes into recurrent epileptiform discharges in rat hippocampal slices.

J Neurophysiol 2011 Jan 29;105(1):172-87. Epub 2010 Sep 29.

Institute for Neurophysiology, Johannes Müller-Center for Physiology, Charité-Universitätsmedizin Berlin, Oudenarder Strasse 16, 13347 Berlin, Germany.

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January 2011

Age- and region-specific effects of anticonvulsants and bumetanide on 4-aminopyridine-induced seizure-like events in immature rat hippocampal-entorhinal cortex slices.

Epilepsia 2011 Jan 24;52(1):94-103. Epub 2010 Sep 24.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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January 2011

Drug refractoriness of epileptiform activity in organotypic hippocampal slice cultures depends on the mode of provocation.

Epilepsy Res 2010 Aug;90(3):304-8

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Tucholskystrasse 2, Berlin, Germany.

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August 2010

In search of models of pharmacoresistant epilepsy.

Epilepsia 2010 Jul;51 Suppl 3:154-9

Institute of Neurophysiology and NeuroCure Research Centre, Charité Universitätsmedizin Berlin, Berlin, Germany.

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July 2010

The range of intrinsic frequencies represented by medial entorhinal cortex stellate cells extends with age.

J Neurosci 2010 Mar;30(13):4585-9

Institute of Neurophysiology, Charité, and NeuroCure Research Center, 10117 Berlin, Germany.

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March 2010

Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures.

Epilepsy Res 2009 Oct 16;86(2-3):113-23. Epub 2009 Jun 16.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Tucholskystrasse 2, D-10117 Berlin, Germany.

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October 2009

Effects of XE991, retigabine, losigamone and ZD7288 on kainate-induced theta-like and gamma network oscillations in the rat hippocampus in vitro.

Brain Res 2009 Oct 20;1295:44-58. Epub 2009 Aug 20.

Institute of Neurophysiology, Johannes Müller-Center of Physiology, Charité-Universitätsmedizin Berlin, Tucholskystrasse 2, 10117 Berlin, Germany.

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October 2009

Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy.

Epilepsy Res 2009 Aug 11;85(2-3):142-9. Epub 2009 Apr 11.

Department of Physiology, Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

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August 2009

Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?

J Neurosci 2009 Aug;29(34):10588-99

Department of Physiology, Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

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August 2009

Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis.

J Neurosci 2009 Jul;29(28):8927-35

Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720-3140, USA.

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July 2009

Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.

Epilepsia 2009 Apr 21;50(4):849-58. Epub 2009 Jan 21.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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April 2009

Monoamines block kainate- and carbachol-induced gamma-oscillations but augment stimulus-induced gamma-oscillations in rat hippocampus in vitro.

Hippocampus 2009 Mar;19(3):273-88

Department of Neurobiology, Johannes Müller-Center for Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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March 2009

Independent positioning of microelectrodes for multisite recordings in vitro.

J Neurosci Methods 2009 Jan 6;176(2):182-5. Epub 2008 Sep 6.

Institut für Neurophysiologie, Johannes Müller Centre of Physiology, CCM, Charité-Universitätsmedizin Berlin, Tucholskystr. 2, D-10117 Berlin, Germany.

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January 2009

C-Type natriuretic peptide modulates pre- and postsynaptic properties in hippocampal area CA1 in vitro.

Biochem Biophys Res Commun 2008 Dec 24;377(3):820-5. Epub 2008 Oct 24.

Institute for Neurophysiology, Johannes Müller Ctr. of Physiology, Charité-Universitätsmedizin Berlin, Tucholskystrasse 2, 10117 Berlin, Germany.

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December 2008

Implication of neuronal Ca2+ -sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia.

Neurobiol Dis 2008 Oct 22;32(1):162-75. Epub 2008 Jul 22.

Signal Transduction Research Group, Neuroscience Research Center, Charité, Universitaetsmedizin Berlin, Germany.

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October 2008

New dangers of anesthesia: isoflurane induced opening of the blood-brain barrier (Commentary on Tétrault et al.).

Authors:
Uwe Heinemann

Eur J Neurosci 2008 Oct;28(7):1329

Institute of Neurophysiology, Charité Universitätsmedizin, Berlin, Germany.

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October 2008

Nitric oxide modulates spreading depolarization threshold in the human and rodent cortex.

Stroke 2008 Apr 28;39(4):1292-9. Epub 2008 Feb 28.

Department of Experimental Neurology, Charité University Medicine Berlin, Berlin, Germany.

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April 2008

GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.

J Neurophysiol 2008 Mar 23;99(3):1523-34. Epub 2008 Jan 23.

Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados (CINVESTAV Apartado Postal 14-740, 07000 Mexico D.F.

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March 2008

Effects of 4-aminopyridine on sharp wave-ripples in rat hippocampal slices.

Neuroreport 2008 Mar;19(4):491-6

Johannes Müller-Center for Physiology, Institute for Neurophysiology, Charité-University Medicine Berlin, Berlin, Germany.

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March 2008

Reduced ictogenic potential of 4-aminopyridine in the perirhinal and entorhinal cortex of kainate-treated chronic epileptic rats.

Neurobiol Dis 2008 Feb 4;29(2):186-200. Epub 2007 Sep 4.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Humboldt Universität, Tucholskystr. 2, D-10117 Berlin, Germany.

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February 2008

Cell and gene therapies in epilepsy--promising avenues or blind alleys?

Trends Neurosci 2008 Feb 16;31(2):62-73. Epub 2008 Jan 16.

Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.

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February 2008

Cholinergic dysfunction in temporal lobe epilepsy.

Epilepsia 2007 ;48 Suppl 5:126-30

Department of Physiology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

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November 2007

Acute and long-term effects of MK-801 on direct cortical input evoked homosynaptic and heterosynaptic plasticity in the CA1 region of the female rat.

Eur J Neurosci 2007 Nov;26(10):2873-83

Institute of Neurophysiology, Johannes Müller Centre of Physiology, Charité-Universitätsmedizin Berlin, Tucholskystrasse 2, 10117 Berlin, Germany.

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November 2007

Hypoxia suppresses kainate-induced gamma-oscillations in rat hippocampal slices.

Neuroreport 2007 Nov;18(17):1827-31

Johannes Mueller-Center for Physiology, Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, Tucholskystrasse 2, 10117 Berlin, Germany.

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November 2007

Two-pore-domain potassium channels contribute to neuronal potassium release and glial potassium buffering in the rat hippocampus.

Brain Res 2007 Oct 17;1173:14-26. Epub 2007 Jul 17.

Institute for Neurophysiology, Charité - Medical University of Berlin, Tucholskystr. 2, 10117 Berlin, Germany.

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October 2007

Impaired hippocampal rhythmogenesis in a mouse model of mesial temporal lobe epilepsy.

Proc Natl Acad Sci U S A 2007 Oct 22;104(44):17530-5. Epub 2007 Oct 22.

Institute of Neurophysiology, Charité Universitätsmedizin Berlin, Tucholskystrasse 2, D-10117 Berlin, Germany.

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October 2007

Synaptic responses in superficial layers of medial entorhinal cortex from rats with kainate-induced epilepsy.

Neurobiol Dis 2007 May 7;26(2):419-38. Epub 2007 Feb 7.

Johannes-Müller-Institute of Physiology at the Charité, Humboldt University Berlin, Tucholskystr. 2, 10117 Berlin, Germany.

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May 2007

Increased inhibitory input to CA1 pyramidal cells alters hippocampal gamma frequency oscillations in the MK-801 model of acute psychosis.

Neurobiol Dis 2007 Mar 12;25(3):545-52. Epub 2006 Dec 12.

Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, Tucholskystr. 2, 10117 Berlin, Germany.

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March 2007

TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis.

Brain 2007 Feb 21;130(Pt 2):535-47. Epub 2006 Nov 21.

Institute of Neurophysiology, Charité University Medicine, Berlin, Germany.

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February 2007

Low-frequency stimulation of the direct cortical input to area CA1 induces homosynaptic LTD and heterosynaptic LTP in the rat hippocampal-entorhinal cortex slice preparation.

Eur J Neurosci 2007 Jan;25(1):251-8

Institute of Neurophysiology, Johannes Müller Ctr. of Physiology, Charité-Universitätsmedizin Berlin, Tucholskystrasse 2, 10117 Berlin, Germany.

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January 2007