Publications by authors named "Ute Wittstock"

35Publications

Novel glucosinolate metabolism in larvae of the leaf beetle Phaedon cochleariae.

Insect Biochem Mol Biol 2020 Sep 10;124:103431. Epub 2020 Jul 10.

Department of Chemical Ecology, Bielefeld University, Universitätsstr. 25, 33615, Bielefeld, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ibmb.2020.103431DOI Listing
September 2020

Glucosinolate Content in Dormant and Germinating Seeds Is Affected by Non-Functional Alleles of Classical Myrosinase and Nitrile-Specifier Protein Genes.

Front Plant Sci 2019 26;10:1549. Epub 2019 Nov 26.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Braunschweig, Germany.

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http://dx.doi.org/10.3389/fpls.2019.01549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901928PMC
November 2019

Synthesis and Biochemical Evaluation of an Artificial, Fluorescent Glucosinolate (GSL).

Chembiochem 2019 09 25;20(18):2341-2345. Epub 2019 Apr 25.

Institute of Organic Chemistry, Technische Universität Carolo Wilhelmina zu Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cbic.2019001
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http://dx.doi.org/10.1002/cbic.201900148DOI Listing
September 2019

Structural diversification during glucosinolate breakdown: mechanisms of thiocyanate, epithionitrile and simple nitrile formation.

Plant J 2019 07 29;99(2):329-343. Epub 2019 Apr 29.

Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle (Saale), Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/tpj.14327
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http://dx.doi.org/10.1111/tpj.14327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850609PMC
July 2019

Sequential regiospecific gem-diprenylation of tetrahydroxyxanthone by prenyltransferases from Hypericum sp.

New Phytol 2019 04 5;222(1):318-334. Epub 2019 Jan 5.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstraße 1, 38106, Braunschweig, Germany.

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http://dx.doi.org/10.1111/nph.15611DOI Listing
April 2019

Molecular identification and characterization of rhodaneses from the insect herbivore Pieris rapae.

Sci Rep 2018 Jul 17;8(1):10819. Epub 2018 Jul 17.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106, Braunschweig, Germany.

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http://dx.doi.org/10.1038/s41598-018-29148-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050342PMC
July 2018

β-Cyanoalanine Synthases and Their Possible Role in Pierid Host Plant Adaptation.

Insects 2017 Jun 18;8(2). Epub 2017 Jun 18.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstrasse 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.3390/insects8020062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492076PMC
June 2017

Biotechnological production of hyperforin for pharmaceutical formulation.

Eur J Pharm Biopharm 2018 May 2;126:10-26. Epub 2017 Apr 2.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Germany; Center of Pharmaceutical Engineering, Technische Universität Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2017.03.024DOI Listing
May 2018

NSP-Dependent Simple Nitrile Formation Dominates upon Breakdown of Major Aliphatic Glucosinolates in Roots, Seeds, and Seedlings of Columbia-0.

Front Plant Sci 2016 1;7:1821. Epub 2016 Dec 1.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig Braunschweig, Germany.

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http://dx.doi.org/10.3389/fpls.2016.01821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131009PMC
December 2016

Cyanide detoxification in an insect herbivore: Molecular identification of β-cyanoalanine synthases from Pieris rapae.

Insect Biochem Mol Biol 2016 Mar 20;70:99-110. Epub 2015 Dec 20.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ibmb.2015.12.004DOI Listing
March 2016

The crystal structure of the thiocyanate-forming protein from Thlaspi arvense, a kelch protein involved in glucosinolate breakdown.

Plant Mol Biol 2015 Sep 11;89(1-2):67-81. Epub 2015 Aug 11.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106, Braunschweig, Germany.

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http://link.springer.com/10.1007/s11103-015-0351-9
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http://dx.doi.org/10.1007/s11103-015-0351-9DOI Listing
September 2015

Molecular models and mutational analyses of plant specifier proteins suggest active site residues and reaction mechanism.

Plant Mol Biol 2014 Jan 3;84(1-2):173-88. Epub 2013 Sep 3.

Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle (Saale), Germany.

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http://dx.doi.org/10.1007/s11103-013-0126-0DOI Listing
January 2014

Evolution of specifier proteins in glucosinolate-containing plants.

BMC Evol Biol 2012 Jul 28;12:127. Epub 2012 Jul 28.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Germany.

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http://dx.doi.org/10.1186/1471-2148-12-127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482593PMC
July 2012

Metabolism of glucosinolate-derived isothiocyanates to glutathione conjugates in generalist lepidopteran herbivores.

Insect Biochem Mol Biol 2012 Mar 13;42(3):174-82. Epub 2011 Dec 13.

Max Planck Institute for Chemical Ecology, Hans-Knoell-Str. 8, 07745 Jena, Germany.

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http://dx.doi.org/10.1016/j.ibmb.2011.12.002DOI Listing
March 2012

A thiocyanate-forming protein generates multiple products upon allylglucosinolate breakdown in Thlaspi arvense.

Phytochemistry 2011 Oct 21;72(14-15):1699-709. Epub 2011 Jul 21.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2011.06.013DOI Listing
October 2011

Insect herbivore counteradaptations to the plant glucosinolate-myrosinase system.

Phytochemistry 2011 Sep 10;72(13):1566-75. Epub 2011 Feb 10.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstr. 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2011.01.016DOI Listing
September 2011

Differential effects of indole and aliphatic glucosinolates on lepidopteran herbivores.

J Chem Ecol 2010 Aug 9;36(8):905-13. Epub 2010 Jul 9.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Braunschweig, Germany.

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http://dx.doi.org/10.1007/s10886-010-9825-zDOI Listing
August 2010

The genetic basis of constitutive and herbivore-induced ESP-independent nitrile formation in Arabidopsis.

Plant Physiol 2009 Jan 5;149(1):561-74. Epub 2008 Nov 5.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, 38106 Braunschweig, Germany.

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http://www.plantphysiol.org/cgi/doi/10.1104/pp.108.130732
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http://dx.doi.org/10.1104/pp.108.130732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613743PMC
January 2009

Formation of simple nitriles upon glucosinolate hydrolysis affects direct and indirect defense against the specialist herbivore, Pieris rapae.

J Chem Ecol 2008 Oct 12;34(10):1311-21. Epub 2008 Sep 12.

Laboratory of Entomology, Wageningen University, 6700 EH, Wageningen, The Netherlands.

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http://dx.doi.org/10.1007/s10886-008-9534-zDOI Listing
October 2008

Tipping the scales--specifier proteins in glucosinolate hydrolysis.

IUBMB Life 2007 Dec;59(12):744-51

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Braunschweig, Germany.

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http://doi.wiley.com/10.1080/15216540701736277
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http://dx.doi.org/10.1080/15216540701736277DOI Listing
December 2007

The genetic basis of a plant-insect coevolutionary key innovation.

Proc Natl Acad Sci U S A 2007 Dec 11;104(51):20427-31. Epub 2007 Dec 11.

Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans Knoell Strasse 8, 07745 Jena, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0706229104
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http://dx.doi.org/10.1073/pnas.0706229104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154447PMC
December 2007

ESP and ESM1 mediate indol-3-acetonitrile production from indol-3-ylmethyl glucosinolate in Arabidopsis.

Phytochemistry 2008 Feb 24;69(3):663-71. Epub 2007 Oct 24.

Max-Planck-Institute for Chemical Ecology, Hans-Knöll-Strasse 8, D-07745 Jena, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2007.08.027DOI Listing
February 2008

Cell- and tissue-specific localization and regulation of the epithiospecifier protein in Arabidopsis thaliana.

Plant Mol Biol 2007 May 16;64(1-2):173-85. Epub 2007 Mar 16.

Department of Biochemistry, Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knöll-Str. 8, D-07745 Jena, Germany.

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http://dx.doi.org/10.1007/s11103-007-9143-1DOI Listing
May 2007

Glucosinolate hydrolysis in Lepidium sativum--identification of the thiocyanate-forming protein.

Plant Mol Biol 2007 Jan 1;63(1):49-61. Epub 2006 Dec 1.

Department of Biochemistry, Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knöll-Str. 8, D-07745, Jena, Germany.

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http://link.springer.com/10.1007/s11103-006-9071-5
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http://dx.doi.org/10.1007/s11103-006-9071-5DOI Listing
January 2007

Glycine conjugates in a lepidopteran insect herbivore--the metabolism of benzylglucosinolate in the cabbage white butterfly, Pieris rapae.

Chembiochem 2006 Dec;7(12):1982-9

Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knöll-Strasse 8, 07745 Jena, Germany.

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http://doi.wiley.com/10.1002/cbic.200600280
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http://dx.doi.org/10.1002/cbic.200600280DOI Listing
December 2006

Altered glucosinolate hydrolysis in genetically engineered Arabidopsis thaliana and its influence on the larval development of Spodoptera littoralis.

J Chem Ecol 2006 Nov;32(11):2333-49

Department of Biochemistry, Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knöll-Str 8, D-07745, Jena, Germany.

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http://dx.doi.org/10.1007/s10886-006-9149-1DOI Listing
November 2006

Comparative biochemical characterization of nitrile-forming proteins from plants and insects that alter myrosinase-catalysed hydrolysis of glucosinolates.

FEBS J 2006 Jun;273(11):2432-46

Max Planck Institute for Chemical Ecology, Department of Biochemistry, Jena, Germany.

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http://dx.doi.org/10.1111/j.1742-4658.2006.05252.xDOI Listing
June 2006

Uptake and turn-over of glucosinolates sequestered in the sawfly Athalia rosae.

Insect Biochem Mol Biol 2005 Oct;35(10):1189-98

Julius-von-Sachs-Institut für Biowissenschaften, Universität Würzburg, Julius-von-Sachs-Platz 3, D-97082 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ibmb.2005.06.001DOI Listing
October 2005

Successful herbivore attack due to metabolic diversion of a plant chemical defense.

Proc Natl Acad Sci U S A 2004 Apr 29;101(14):4859-64. Epub 2004 Mar 29.

Department of Biochemistry, Max Planck Institute for Chemical Ecology, Hans-Knöll-Strasse 8, D-07745 Jena, Germany.

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http://dx.doi.org/10.1073/pnas.0308007101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC387339PMC
April 2004

Constitutive plant toxins and their role in defense against herbivores and pathogens.

Curr Opin Plant Biol 2002 Aug;5(4):300-7

Max Planck Institute for Chemical Ecology, Department of Biochemistry, Winzerlaer Strasse 10, Beutenberg Campus, D-07745 Jena, Germany.

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http://dx.doi.org/10.1016/s1369-5266(02)00264-9DOI Listing
August 2002

Glucosinolate research in the Arabidopsis era.

Trends Plant Sci 2002 Jun;7(6):263-70

Dept Biochemistry, Max Planck Institute for Chemical Ecology, Winzerlaer Str. 10, D-07745 Jena, Germany.

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http://dx.doi.org/10.1016/s1360-1385(02)02273-2DOI Listing
June 2002