Ute Hegenbart

Amyloidosis Research and Treatment Center, Foundation "Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo", Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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January 2021

CAR T cells or allogeneic transplantation as standard of care for advanced large B-cell lymphoma: an intent-to-treat comparison.

Authors:

Peter Dreger Sascha Dietrich Maria-Luisa Schubert Lorenz Selberg Andrea Bondong Mandy Wegner Peter Stadtherr Christoph Kimmich Florentina Kosely Anita Schmitt Petra Pavel Nora Liebers Thomas Luft Ute Hegenbart Aleksandar Radujkovic Anthony Dick Ho Carsten Müller-Tidow Michael Schmitt

Blood Adv 2020 Dec;4(24):6157-6168

Department of Medicine V, University of Heidelberg, Heidelberg, Germany; and.

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December 2020

Initial experience with percutaneous mitral valve repair in patients with cardiac amyloidosis.

Authors:

Martin J Volz Sven T Pleger Andreas Weber Nicolas A Geis Sonja Hamed Derliz Mereles Ute Hegenbart Hugo A Katus Norbert Frey Philip W Raake Michael M Kreusser

Eur J Clin Invest 2020 Dec 16:e13473. Epub 2020 Dec 16.

Division of Cardiology, Department of Internal Medicine III, University of Heidelberg, Heidelberg, Germany.

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December 2020

Real-world outcomes in non-endemic hereditary transthyretin amyloidosis with polyneuropathy: a 20-year German single-referral centre experience.

Authors:

Matthias N Ungerer Ernst Hund Jan C Purrucker Laura Huber Christoph Kimmich Fabian Aus dem Siepen Selina Hein Arnt V Kristen Katrin Hinderhofer Jennifer Kollmer Stefan Schönland Ute Hegenbart Markus Weiler

Amyloid 2020 Dec 7:1-9. Epub 2020 Dec 7.

Amyloidosis Center, Heidelberg University Hospital, Heidelberg, Germany.

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December 2020

Letermovir prophylaxis is effective in preventing cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation: single-center real-world data.

Authors:

Patrick Derigs Aleksandar Radujkovic Maria-Luisa Schubert Paul Schnitzler Tilman Schöning Carsten Müller-Tidow Ute Hegenbart Stefan O Schönland Thomas Luft Peter Dreger Michael Schmitt

Ann Hematol 2020 Dec 3. Epub 2020 Dec 3.

Department of Internal Medicine V (Hematology/Oncology/Rheumatology), Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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December 2020

Targeting transthyretin - Mechanism-based treatment approaches and future perspectives in hereditary amyloidosis.

Authors:

Maike F Dohrn Sandra Ihne Ute Hegenbart Jessica Medina Stephan L Züchner Teresa Coelho Katrin Hahn

J Neurochem 2020 Nov 6. Epub 2020 Nov 6.

Department of Neurology, Charité University Medicine, Berlin, Germany.

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November 2020

Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability.

Authors:

Tejaswini Pradhan Karthikeyan Annamalai Riddhiman Sarkar Stefanie Huhn Ute Hegenbart Stefan Schönland Marcus Fändrich Bernd Reif

J Biol Chem 2020 Dec 22;295(52):18474-18484. Epub 2020 Oct 22.

Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und UmweltInstitute of Structural Biology (STB), Neuherberg, Germany

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December 2020

Solid state NMR assignments of a human λ-III immunoglobulin light chain amyloid fibril.

Authors:

Tejaswini Pradhan Karthikeyan Annamalai Riddhiman Sarkar Ute Hegenbart Stefan Schönland Marcus Fändrich Bernd Reif

Biomol NMR Assign 2020 Sep 18. Epub 2020 Sep 18.

Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit Und Umwelt, Institute of Structural Biology, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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September 2020

Localized immunoglobulin light chain amyloidosis: Novel insights including prognostic factors for local progression.

Authors:

Marco Basset Kamal Hummedah Christoph Kimmich Kaya Veelken Tobias Dittrich Simone Brandelik Michael Kreuter Jessica Hassel Nikolaus Bosch Christiane Stuhlmann-Laeisz Norbert Blank Carsten Müller-Tidow Christoph Röcken Ute Hegenbart Stefan Schönland

Am J Hematol 2020 Jun 29. Epub 2020 Jun 29.

Medical Department V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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June 2020

CT features in amyloidosis of the respiratory system - Comprehensive analysis in a tertiary referral center cohort.

Authors:

Simone Christine Brandelik Claus Peter Heussel Hans-Ulrich Kauczor Christoph Röcken Laura Huber Marco Basset Christoph Kimmich Stefan Olaf Schönland Ute Hegenbart Johanna Nattenmüller

Eur J Radiol 2020 Aug 13;129:109123. Epub 2020 Jun 13.

Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany; Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Im Neuenheimer Feld 110, 69120 Heidelberg, Germany; Amyloidosis Center, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

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August 2020

Prognosis and Staging of AL Amyloidosis.

Authors:

Tobias Dittrich Christoph Kimmich Ute Hegenbart Stefan O Schönland

Acta Haematol 2020 22;143(4):388-400. Epub 2020 Jun 22.

Department of Internal Medicine V, Division of Hematology/Oncology, Heidelberg University Hospital, Heidelberg, Germany,

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September 2020

The impact of allogeneic hematopoietic cell transplantation on the mortality of poor-risk non-Hodgkin lymphoma: an intent-to-transplant analysis.

Authors:

Lorenz Selberg Peter Stadtherr Sascha Dietrich T Hien Tran Thomas Luft Ute Hegenbart Andrea Bondong Julia Meissner Nora Liebers Michael Schmitt Anthony Dick Ho Carsten Müller-Tidow Peter Dreger

Bone Marrow Transplant 2021 Jan 18;56(1):30-37. Epub 2020 Jun 18.

Department Medicine V, University of Heidelberg, Heidelberg, Germany.

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January 2021

Challenges in the management of patients with systemic light chain (AL) amyloidosis during the COVID-19 pandemic.

Authors:

Efstathios Kastritis Ashutosh Wechalekar Stefan Schönland Vaishali Sanchorawala Giampaolo Merlini Giovanni Palladini Monique Minnema Murielle Roussel Arnaud Jaccard Ute Hegenbart Shaji Kumar Maria T Cibeira Joan Blade Meletios A Dimopoulos

Br J Haematol 2020 08 4;190(3):346-357. Epub 2020 Jul 4.

Plasma Cell Dyscrasia Unit, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.

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August 2020

Pomalidomide and dexamethasone grant rapid haematologic responses in patients with relapsed and refractory AL amyloidosis: a European retrospective series of 153 patients.

Authors:

Paolo Milani Faye Sharpley Stefan O Schönland Marco Basset Shameem Mahmood Mario Nuvolone Christoph Kimmich Andrea Foli Sajitha Sachchithanantham Giampaolo Merlini Ashutosh Wechalekar Giovanni Palladini Ute Hegenbart

Amyloid 2020 Dec 25;27(4):231-236. Epub 2020 May 25.

Medical Department V, Amyloidosis Centrum, University Hospital, University of Heidelberg, Heidelberg, Germany.

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December 2020

Magnetization transfer ratio quantifies polyneuropathy in hereditary transthyretin amyloidosis.

Authors:

Jennifer Kollmer Ute Hegenbart Christoph Kimmich Ernst Hund Jan C Purrucker John M Hayes Stephen I Lentz Georges Sam Johann M E Jende Stefan O Schönland Martin Bendszus Sabine Heiland Markus Weiler

Ann Clin Transl Neurol 2020 05 25;7(5):799-807. Epub 2020 Apr 25.

Amyloidosis Center Heidelberg, Heidelberg University Hospital, Heidelberg, Germany.

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May 2020

Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.

Authors:

Pamina Kazman Marie-Theres Vielberg María Daniela Pulido Cendales Lioba Hunziger Benedikt Weber Ute Hegenbart Martin Zacharias Rolf Köhler Stefan Schönland Michael Groll Johannes Buchner

Elife 2020 03 10;9. Epub 2020 Mar 10.

Center for Integrated Protein Science Munich at the Department Chemie, Technische Universität München, Garching, Germany.

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March 2020

Daratumumab for systemic AL amyloidosis: prognostic factors and adverse outcome with nephrotic-range albuminuria.

Authors:

Christoph R Kimmich Tobias Terzer Axel Benner Tobias Dittrich Kaya Veelken Alexander Carpinteiro Timon Hansen Hartmut Goldschmidt Anja Seckinger Dirk Hose Anna Jauch Stefan Wörner Jörg Beimler Carsten Müller-Tidow Ute Hegenbart Stefan O Schönland

Blood 2020 04;135(18):1517-1530

Division of Hematology/Oncology, Department of Internal Medicine V, and.

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April 2020

High leukemia-free survival after TBI-based conditioning and mycophenolate mofetil-containing immunosuppression in patients allografted for chronic myelomonocytic leukemia: a single-center experience.

Authors:

Aleksandar Radujkovic Ute Hegenbart Carsten Müller-Tidow Klaus Herfarth Peter Dreger Thomas Luft

Ann Hematol 2020 Apr 8;99(4):855-866. Epub 2020 Feb 8.

Department of Internal Medicine V, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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April 2020

Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance.

Leukemia 2020 04 6;34(4):1187-1191. Epub 2019 Nov 6.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120, Heidelberg, Germany.

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April 2020

A novel risk score to predict survival in advanced heart failure due to cardiac amyloidosis.

Authors:

Michael M Kreusser Martin J Volz Benjamin Knop Philipp Ehlermann Bastian Schmack Arjang Ruhparwar Ute Hegenbart Stefan O Schönland Hugo A Katus Philip W Raake

Clin Res Cardiol 2020 Jun 19;109(6):700-713. Epub 2019 Oct 19.

Division of Cardiology, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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June 2020

Prognostic value of novel imaging parameters derived from standard cardiovascular magnetic resonance in high risk patients with systemic light chain amyloidosis.

Authors:

Nisha Arenja Florian Andre Johannes H Riffel Fabian Aus dem Siepen Ute Hegenbart Stefan Schönland Arnt V Kristen Hugo A Katus Sebastian J Buss

J Cardiovasc Magn Reson 2019 08 22;21(1):53. Epub 2019 Aug 22.

Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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August 2019

New sequence variants in patients affected by amyloidosis show transthyretin instability by isoelectric focusing.

Authors:

Katrin Hinderhofer Christian Obermaier Ute Hegenbart Stefan Schönland Marc Seidler Iris Sommer-Ort Ulrike Barth

Amyloid 2019 Jun 10;26(2):85-93. Epub 2019 May 10.

a Institute of Human Genetics, Heidelberg University Hospital , Heidelberg , Germany.

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June 2019

Carpal tunnel syndrome and spinal canal stenosis: harbingers of transthyretin amyloid cardiomyopathy?

Authors:

Fabian Aus dem Siepen Selina Hein Sofie Prestel Christian Baumgärtner Stefan Schönland Ute Hegenbart Christoph Röcken Hugo A Katus Arnt V Kristen

Clin Res Cardiol 2019 Dec 5;108(12):1324-1330. Epub 2019 Apr 5.

Department of Cardiology, Angiology and Respiratory Medicine, Amyloidosis Center, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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December 2019