Publications by authors named "Ute Fischer"

73Publications

Regional BCG vaccination policy in former East- and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia.

Leukemia 2020 08 18;34(8):2217-2219. Epub 2020 Jun 18.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.1038/s41375-020-0871-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301049PMC
August 2020

Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations.

J Allergy Clin Immunol 2020 Oct 9;146(4):901-911. Epub 2020 Apr 9.

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; CIBSS (Centre for Integrative Biological Signalling Studies), University of Freiburg, Freiburg, Germany; RESIST - Cluster of Excellence 2155 to Hanover Medical School, Satellite Center Freiburg, Freiburg, Germany; Institute of Immunology and Transplantation, Royal Free Hospital and University College London, London, United Kingdom; DZIF (German Center for Infection Research) Satellite Center Freiburg, Freiburg, Germany; Rheumatology and Clinical Immunology, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.11.051DOI Listing
October 2020

Insights into the prenatal origin of childhood acute lymphoblastic leukemia.

Cancer Metastasis Rev 2020 03;39(1):161-171

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1007/s10555-019-09841-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098935PMC
March 2020

The preleukemic TCF3-PBX1 gene fusion can be generated in utero and is present in ≈0.6% of healthy newborns.

Blood 2019 10;134(16):1355-1358

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1182/blood.2019002215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005361PMC
October 2019

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility.

Leukemia 2019 09 9;33(9):2331-2335. Epub 2019 Apr 9.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.

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http://dx.doi.org/10.1038/s41375-019-0459-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756027PMC
September 2019

Five percent of healthy newborns have an fusion as revealed by DNA-based GIPFEL screening.

Blood 2018 02 8;131(7):821-826. Epub 2018 Jan 8.

Department of Pediatric Oncology, Hematology, and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.1182/blood-2017-09-808402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909885PMC
February 2018

Smoldering Development of Acute Megakaryoblastic Leukemia with Clonal Evolution in an Infant without Down Syndrome.

Klin Padiatr 2017 11 13;229(6):352-354. Epub 2017 Nov 13.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine University of Duesseldorf, Duesseldorf, Germany.

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http://dx.doi.org/10.1055/s-0043-113446DOI Listing
November 2017

Infection as a cause of childhood leukemia: virus detection employing whole genome sequencing.

Haematologica 2017 05 2;102(5):e179-e183. Epub 2017 Feb 2.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.

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http://dx.doi.org/10.3324/haematol.2016.155382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685284PMC
May 2017

Prefabrication of a ribosomal protein subcomplex essential for eukaryotic ribosome formation.

Elife 2016 12 8;5. Epub 2016 Dec 8.

Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.7554/eLife.21755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148605PMC
December 2016

De novo PIK3R1 gain-of-function with recurrent sinopulmonary infections, long-lasting chronic CMV-lymphadenitis and microcephaly.

Clin Immunol 2016 Jan 31;162:27-30. Epub 2015 Oct 31.

University of Duesseldorf, Medical Faculty, Department of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Duesseldorf, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616153005
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http://dx.doi.org/10.1016/j.clim.2015.10.008DOI Listing
January 2016

Eukaryotic Ribosome Assembly and Nuclear Export.

Int Rev Cell Mol Biol 2015 5;319:107-40. Epub 2015 Aug 5.

Institute of Biochemistry (IBC), Department of Biology (D-BIOL), ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/bs.ircmb.2015.07.002DOI Listing
April 2016

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

Nat Genet 2015 Sep 27;47(9):1020-1029. Epub 2015 Jul 27.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1038/ng.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603357PMC
September 2015

Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients.

Leuk Res 2015 Sep 14;39(9):990-1001. Epub 2015 Jun 14.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2015.06.005DOI Listing
September 2015

Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease.

Haematologica 2015 Sep 25;100(9):1189-98. Epub 2015 Jun 25.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany

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http://dx.doi.org/10.3324/haematol.2014.114967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800681PMC
September 2015

Autoimmune lymphoproliferative syndrome-like disease in patients with LRBA mutation.

Clin Immunol 2015 Jul 27;159(1):84-92. Epub 2015 Apr 27.

Pediatric Hematology/Oncology and Bone Marrow Transplantation, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.clim.2015.04.007DOI Listing
July 2015

A non-canonical mechanism for Crm1-export cargo complex assembly.

Elife 2015 Apr 21;4. Epub 2015 Apr 21.

Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.

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https://elifesciences.org/articles/05745
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http://dx.doi.org/10.7554/eLife.05745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402694PMC
April 2015

A novel homozygous Fas ligand mutation leads to early protein truncation, abrogation of death receptor and reverse signaling and a severe form of the autoimmune lymphoproliferative syndrome.

Clin Immunol 2014 Dec 24;155(2):231-7. Epub 2014 Oct 24.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.10.006DOI Listing
December 2014

Using a team-centered approach to evaluate effectiveness of nurse-physician communications.

J Obstet Gynecol Neonatal Nurs 2014 Nov-Dec;43(6):684-94. Epub 2014 Aug 26.

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http://dx.doi.org/10.1111/1552-6909.12486DOI Listing
December 2015

Mycoplasma salivarium as a dominant coloniser of Fanconi anaemia associated oral carcinoma.

PLoS One 2014 18;9(3):e92297. Epub 2014 Mar 18.

Department of Paediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092297PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958540PMC
November 2014

Limited efficacy of specific HDAC6 inhibition in urothelial cancer cells.

Cancer Biol Ther 2014 Jun 11;15(6):742-57. Epub 2014 Mar 11.

Department of Urology; Heinrich-Heine-University; Medical Faculty; Duesseldorf, Germany.

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http://dx.doi.org/10.4161/cbt.28469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049790PMC
June 2014

MTDH/AEG-1 contributes to central features of the neoplastic phenotype in bladder cancer.

Urol Oncol 2014 Jul 2;32(5):670-7. Epub 2014 Feb 2.

Pediatric Inherited Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Genetics and Molecular Biology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2013.11.005DOI Listing
July 2014

Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia.

Genes Chromosomes Cancer 2013 Jun 18;52(6):564-79. Epub 2013 Mar 18.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.1002/gcc.22054DOI Listing
June 2013

Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers.

Urol Oncol 2013 Nov 1;31(8):1770-9. Epub 2012 Sep 1.

Department of Urology, Heinrich-Heine-University, Medical Faculty, Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2012.06.015DOI Listing
November 2013

Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: facts and artefacts.

Toxicol In Vitro 2012 Mar 14;26(2):323-34. Epub 2011 Dec 14.

Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.tiv.2011.12.006DOI Listing
March 2012

Natalizumab and impedance of the homing of CD34+ hematopoietic progenitors.

Arch Neurol 2011 Nov;68(11):1428-31

Department of Hematology, Oncology, and Clinical Immunology, University of Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1001/archneurol.2011.238DOI Listing
November 2011

New insights into the molecular pathology of radiation-induced pneumopathy.

Radiother Oncol 2011 Oct 29;101(1):86-92. Epub 2011 Jun 29.

Institute of Cell Biology (Cancer Research), University Hospital Essen, Germany.

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http://dx.doi.org/10.1016/j.radonc.2011.05.064DOI Listing
October 2011

Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.

J Cell Sci 2009 Dec 17;122(Pt 24):4481-91. Epub 2009 Nov 17.

Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1242/jcs.055772DOI Listing
December 2009

Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity.

Mol Cell Biol 2009 Mar 22;29(5):1235-48. Epub 2008 Dec 22.

Manitoba Institute of Cell Biology, CancerCare Manitoba, University of Manitoba, Winnipeg, Manitoba R3E 0V9, Canada.

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http://dx.doi.org/10.1128/MCB.00668-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643822PMC
March 2009

Expertise and age differences in pilot decision making.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2009 22;16(1):33-55. Epub 2008 Jul 22.

Institute of Aviation, University of Illinois at Urbana-Champaign, Savoy, IL 244-8757, USA.

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http://dx.doi.org/10.1080/13825580802195641DOI Listing
January 2009

Complete downmodulation of P-selectin glycoprotein ligand in monocytes undergoing apoptosis.

Arterioscler Thromb Vasc Biol 2008 Jul 1;28(7):1375-8. Epub 2008 May 1.

Institut für Pharmakologie, Universität Duisburg-Essen, Universitätsklinikum Essen, Hufelandstr. 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.108.166629DOI Listing
July 2008

Does caspase inhibition promote clonogenic tumor growth?

Cell Cycle 2007 Dec 2;6(24):3048-53. Epub 2007 Oct 2.

Institute of Molecular Medicine, Heinrich-Heine-University, Düsseldorf, Germany.

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http://dx.doi.org/10.4161/cc.6.24.5118DOI Listing
December 2007

Local DNA features affect RNA-directed transcriptional gene silencing and DNA methylation.

Plant J 2008 Jan 27;53(1):1-10. Epub 2007 Oct 27.

Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Corrensstrasse 3, 06466 Gatersleben, Germany.

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http://doi.wiley.com/10.1111/j.1365-313X.2007.03311.x
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http://dx.doi.org/10.1111/j.1365-313X.2007.03311.xDOI Listing
January 2008

Cutting-edge apoptosis-based therapeutics: a panacea for cancer?

BioDrugs 2007 ;21(5):273-97

Institute of Molecular Medicine, Heinrich-Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.2165/00063030-200721050-00001DOI Listing
February 2008

Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver.

Hepatology 2007 Nov;46(5):1498-508

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/hep.21846DOI Listing
November 2007

Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment.

Blood 2007 Nov 25;110(10):3662-72. Epub 2007 Jul 25.

Institute of Molecular Medicine, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1182/blood-2007-02-073213DOI Listing
November 2007

Linguistic correlates of team performance: toward a tool for monitoring team functioning during space missions.

Aviat Space Environ Med 2007 May;78(5 Suppl):B86-95

School of Lit., Communication and Culture, Georgia Institute of Technology, 686 Cherry Street, Atlanta, GA 30332-0165, USA.

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May 2007

Multiple virulence factors are required for Staphylococcus aureus-induced apoptosis in endothelial cells.

Cell Microbiol 2005 Aug;7(8):1087-97

Institute of Medical Microbiology, University Hospital of Münster, Domagkstrasse 10, D-48149 Münster, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2005.00533.xDOI Listing
August 2005

Multiple virulence factors are required for Staphylococcus aureus-induced apoptosis in endothelial cells.

Cell Microbiol 2005 Aug;7(8):1087-97

Institute of Medical Microbiology, University Hospital of Münster, Domagkstrasse 10, D-48149 Münster, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2005.00533.xDOI Listing
August 2005

Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner.

Mol Cell Biol 2005 Apr;25(7):2808-18

Institute of Molecular Medicine, University of Düsseldorf, Building 23.12, Universitätsstrasse 1, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1128/MCB.25.7.2808-2818.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1061657PMC
April 2005

Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner.

Mol Cell Biol 2005 Apr;25(7):2808-18

Institute of Molecular Medicine, University of Düsseldorf, Building 23.12, Universitätsstrasse 1, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1128/MCB.25.7.2808-2818.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1061657PMC
April 2005

Overexpression of NtERF5, a new member of the tobacco ethylene response transcription factor family enhances resistance to tobacco mosaic virus.

Mol Plant Microbe Interact 2004 Oct;17(10):1162-71

Albrecht-von-Haller Institut, Universität Göttingen, Untere Karspüle 2, D-37073 Göttingen, Germany.

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http://dx.doi.org/10.1094/MPMI.2004.17.10.1162DOI Listing
October 2004

Overexpression of NtERF5, a new member of the tobacco ethylene response transcription factor family enhances resistance to tobacco mosaic virus.

Mol Plant Microbe Interact 2004 Oct;17(10):1162-71

Albrecht-von-Haller Institut, Universität Göttingen, Untere Karspüle 2, D-37073 Göttingen, Germany.

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http://dx.doi.org/10.1094/MPMI.2004.17.10.1162DOI Listing
October 2004

Stable transgenic expression of IL-2 and HSV1-tk by single and fusion tumor cell lines bearing EWS/FLI-1 chimeric genes.

Pediatr Hematol Oncol 2003 Mar;20(2):119-40

Children's Cancer Research Center, Department of Pediatrics and BioCenter, Martin-Luther University Halle-Wittenberg, Halle/Saale, Germany.

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http://dx.doi.org/10.1080/0880010390158612DOI Listing
March 2003

Differential cytotoxicity and bystander effect of the rabbit cytochrome P450 4B1 enzyme gene by two different prodrugs: implications for pharmacogene therapy.

Cancer Gene Ther 2002 Feb;9(2):178-88

Department of Pediatric Hematology and Oncology, University Children's Hospital, Heinrich Heine University, Duesseldorf, Germany.

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http://dx.doi.org/10.1038/sj.cgt.7700422DOI Listing
February 2002