Uta Dirksen

Uta Dirksen

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Uta Dirksen

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Impact of the Interdisciplinary Tumor Board of the Cooperative Ewing Sarcoma Study Group on local therapy and overall survival of Ewing sarcoma patients after induction therapy.

Pediatr Blood Cancer 2018 12 7;65(12):e27384. Epub 2018 Aug 7.

Department of Pediatrics III, West German Cancer Centre, German Cancer Research Centre, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.27384DOI Listing
December 2018

Defining a Characteristic Gene Expression Set Responsible for Cancer Stem Cell-Like Features in a Sub-Population of Ewing Sarcoma Cells CADO-ES1.

Int J Mol Sci 2018 Dec 6;19(12). Epub 2018 Dec 6.

Institute of Bioinformatics, Faculty of Medicine, University of Münster, 48149 Münster, Germany.

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http://dx.doi.org/10.3390/ijms19123908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321634PMC
December 2018

Impact of Whole Lung Irradiation on Survival Outcome in Patients With Lung Relapsed Ewing Sarcoma.

Int J Radiat Oncol Biol Phys 2018 11 3;102(3):584-592. Epub 2018 Jul 3.

Pediatrics III, Hematology/ Oncology, West German Cancer Center and German Cancer Research Center, University Hospital Essen, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.06.032DOI Listing
November 2018

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

Eur J Cancer 2018 11 29;103:227-237. Epub 2018 Sep 29.

German Childhood Cancer Registry (GCCR), Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Mainz, Germany.

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http://dx.doi.org/10.1016/j.ejca.2018.08.007DOI Listing
November 2018

Age dependency of primary tumor sites and metastases in patients with Ewing sarcoma.

Pediatr Blood Cancer 2018 09 1;65(9):e27251. Epub 2018 Jun 1.

University Hospital Essen, Pediatrics III, Sarcoma Centre, West German Cancer, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.27251DOI Listing
September 2018

High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008.

J Clin Oncol 2018 Sep 6:JCO2018782516. Epub 2018 Sep 6.

Jeremy Whelan, University College Hospital; Ian Judson, Institute of Cancer Research, London; Bernadette Brennan, Royal Manchester Children's Hospital, Manchester; Bruce Morland, Birmingham Children's Hospital; Keith Wheatley, University of Birmingham, Birmingham; Ian Lewis, Leeds Community Healthcare National Health Service Trust, Leeds; Alan Craft, Newcastle University, Newcastle upon Tyne, United Kingdom; Marie-Cecile Le Deley and Cyril Lervat, Centre Oscar Lambret, Lille; Gwénaël Le Teuff, Nathalie Gaspar, and Odile Oberlin, Institut Gustave Roussy, Villejuif; Jean-Yves Blay, Centre Léon Bérard; Perrine Marec-Berard, Institute of Pediatric Onco-Haematology, Lyon; Marie-Pierre Castex, Centre Hospitalier Universitaire de Toulouse, Toulouse; Jean-Claude Gentet, Centre Hospitalier Universitaire La Timone, Marseille; Marta Jimenez, Unicancer; Valerie Laurence and Jean Michon, Institut Curie, Paris; France; Uta Dirksen, Sebastian Bauer, Andreas Ranft, University Hospital Essen, Essen; Susanne Amler, Institut für Biometrie und Klinische Forschung; Wolfgang Hartmann and Heribert Juergens, Universitätsklinikum, Münster, Münster; Stefan Bielack, Klinikum Stuttgart, Stuttgart; Stefan Burdach, Comprehensive Cancer Center, München; Dagmar Dilloo, University-Clinic Bonn, Bonn; Angelika Eggert, Charité University; Peter Reichardt, HELIOS Klinikum Berlin-Buch, Berlin; Wolf-Achim Hassenpflug, University Medical Center Hamburg-Eppendorf, Hamburg; Thomas Klingebiel, Childrens University Hospital, Frankfurt; Udo Kontny, University Medical Center Aachen, Aachen; Michael Paulussen, Children's and Adolescents' Hospital, Datteln; Germany; Douglas S. Hawkins, Seattle Children's Hospital, Seattle, WA; Hans Gelderblom, Leiden University Medical Center, Leiden; Hendrik van den Berg, University of Amsterdam, Amsterdam, the Netherlands; Lars Hjorth, Skane University Hospital, Lund, Sweden; Jarmila Kruseova, Faculty Hospital Motol Prague, Prague, Czech Republic; Ruth Ladenstein, St Anna Children's Hospital and Children's Cancer Research Institute, Vienna, Austria; Sandrine Marreaud, European Organisation for Research and Treatment of Cancer, Brussels, Belgium.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.2516
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http://dx.doi.org/10.1200/JCO.2018.78.2516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209090PMC
September 2018

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41586-018-0167-2DOI Listing
July 2018

Ewing sarcoma.

Nat Rev Dis Primers 2018 07 5;4(1). Epub 2018 Jul 5.

German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41572-018-0003-xDOI Listing
July 2018

The CXCR4 antagonist plerixafor (AMD3100) promotes proliferation of Ewing sarcoma cell lines in vitro and activates receptor tyrosine kinase signaling.

Cell Commun Signal 2018 05 18;16(1):21. Epub 2018 May 18.

Department of General Pediatrics, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

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http://dx.doi.org/10.1186/s12964-018-0233-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960216PMC
May 2018

The landscape of genomic alterations across childhood cancers.

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature25480DOI Listing
March 2018

Pediatric bone tumors in Germany from 1987 to 2011: incidence rates, time trends and survival.

Acta Oncol 2016 Sep - Oct;55(9-10):1145-1151. Epub 2016 Aug 23.

d Institute for Medical Biostatistics, Epidemiology and Informatics (IMBEI) , University Medical Centre Mainz , Mainz , Germany.

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http://dx.doi.org/10.1080/0284186X.2016.1195509DOI Listing
January 2018

Programmed cell death ligand 1 (PD-L1) expression is not a predominant feature in Ewing sarcomas.

Pediatr Blood Cancer 2018 Jan 4;65(1). Epub 2017 Sep 4.

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.26719DOI Listing
January 2018

Rhabdomyosarcoma, Ewing Sarcoma, and Other Round Cell Sarcomas.

J Clin Oncol 2018 01 8;36(2):168-179. Epub 2017 Dec 8.

Alberto S. Pappo, St. Jude Children's Research Hospital, Memphis, TN; and Uta Dirksen, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1200/JCO.2017.74.7402DOI Listing
January 2018

Results for patients with sarcoma not otherwise specified and other diagnoses than Ewing sarcoma treated according to the Euro-EWING 99 trial.

Pediatr Blood Cancer 2017 Oct 24;64(10). Epub 2017 Apr 24.

Department of Pediatric Hematology and Oncology, University Hospital Muenster, Westfalian Wilhelms University, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.26524DOI Listing
October 2017

Quality of Survivorship in a Rare Disease: Clinicofunctional Outcome and Physical Activity in an Observational Cohort Study of 618 Long-Term Survivors of Ewing Sarcoma.

J Clin Oncol 2017 May 29;35(15):1704-1712. Epub 2017 Mar 29.

Andreas Ranft, Christiane Hoffmann, Ann-Christin Warby, Claudia Rossig, Uta Dirksen, and Herbert Juergens, University Children's Hospital; Corinna Seidel, and Dieter Rosenbaum, University Hospital Muenster; Michael Paulussen, Witten/Herdecke University, Datteln, Germany; Henk van den Berg, Emma Children's Hospital, Amsterdam, the Netherlands; and Ruth Ladenstein, Children's Cancer Research Institute, Wien, Austria.

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http://dx.doi.org/10.1200/JCO.2016.70.6226DOI Listing
May 2017

Sarcomas of Soft Tissue and Bone.

Prog Tumor Res 2016 5;43:128-41. Epub 2016 Sep 5.

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http://dx.doi.org/10.1159/000447083DOI Listing
April 2017

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/ajmg.a.38142DOI Listing
April 2017

Suberanilohydroxamic acid (vorinostat) synergistically enhances the cytotoxicity of doxorubicin and cisplatin in osteosarcoma cell lines.

Anticancer Drugs 2016 11;27(10):1001-10

Departments of aPediatric Hematology and Oncology bGeneral Pediatrics, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1097/CAD.0000000000000418DOI Listing
November 2016

Recommendations for Premature Ovarian Insufficiency Surveillance for Female Survivors of Childhood, Adolescent, and Young Adult Cancer: A Report From the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration With the PanCareSurFup Consortium.

J Clin Oncol 2016 10 25;34(28):3440-50. Epub 2016 Jul 25.

Wendy van Dorp and Sebastian J. Neggers, Erasmus University Medical Centre; Wendy van Dorp, Sophia Children's Hospital, Rotterdam; Renée L. Mulder and Leontien C.M. Kremer, Emma Children's Hospital and Academic Medical Centre; Marleen H. van den Berg, Eline van Dulmen-den Broeder, and Cornelis B. Lambalk, Vrije Universiteit Medical Center, Amsterdam; Marry M. van den Heuvel-Eibrink, Princess Maxima Center for Pediatric Oncology; Hanneke M. van Santen, Wilhelmina Children's Hospital, University Medical Center, Utrecht, the Netherlands; Melissa M. Hudson, St Jude Children's Research Hospital, Memphis, TN; Jennifer M. Levine, Columbia University Medical Center; Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York; Louis S. Constine, University of Rochester Medical Center, Rochester, NY; Natascia di Iorgi, University of Genoa; Riccardo Haupt, Istituto Giannina Gaslini, Genoa; Andreas Corrias and Alesandro Mussa, University of Turin, Turin; Alberto Revelli, S. Anna Hospital and University of Torino, Torino, Italy; Assunta Albanese, St George's University Hospitals NHS Foundation Trust; Gill Levitt and Alison Leiper, Great Ormond St Hospital for Children NHS Foundation Trust, London; Roderick Skinner, Great North Children's Hospital and Newcastle University, Newcastle upon Tyne; Andrew Toogood, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham; William H. Wallace, Royal Hospital for Sick Children, Edinburgh, United Kingdom; Saro H. Armenian, City of Hope, Duarte, CA; Smita Bhatia and Wendy Landier, University of Alabama at Birmingham, Birmingham, AL; Rebecca Deans, University of New South Wales, Sydney, New South Wales, Australia; Uta Dirksen, Westfalian Wilhelms University Muenster, University Hospital Muenster, Germany; Clarisa R. Gracia, University of Pennsylvania, Philadelphia, PA; Lars Hjorth, Skåne University Hospital and Lund University, Lund, Sweden; Leah Kroon, Seattle Children's Hospital, Seat

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http://jco.ascopubs.org/content/34/28/3440.full.pdf
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http://dx.doi.org/10.1200/JCO.2015.64.3288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569686PMC
October 2016

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.

Eur J Cancer 2016 09 29;65:91-101. Epub 2016 Jul 29.

Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg, 69120, Germany; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.009DOI Listing
September 2016

Can postoperative radiotherapy be omitted in localised standard-risk Ewing sarcoma? An observational study of the Euro-E.W.I.N.G group.

Eur J Cancer 2016 07 10;61:128-36. Epub 2016 May 10.

Biostatistics Unit, Gustave Roussy, Villejuif, France; CESP Centre for Research in Epidemiology and Population Health, INSERM U1018, Team-2, Paris-Sud University, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.03.075DOI Listing
July 2016

Management and Outcome of Ewing Sarcoma of the Head and Neck.

Pediatr Blood Cancer 2016 Apr 24;63(4):604-10. Epub 2015 Dec 24.

Department of Pediatric Hematology and Oncology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.25830DOI Listing
April 2016

Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.

Clin Cancer Res 2015 Nov 15;21(21):4935-46. Epub 2015 Jul 15.

Department of Medicine A, Hematology, and Oncology, University Hospital of Muenster, Muenster, Germany. Department of Medicine IV, Hematology and Oncology, State Center for Cell and Gene Therapy, University Hospital Halle, Halle (Saale), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2744DOI Listing
November 2015

Suberoylanilide hydroxamic acid synergistically enhances the antitumor activity of etoposide in Ewing sarcoma cell lines.

Anticancer Drugs 2015 Sep;26(8):843-51

aDepartment of Pediatric Hematology and Oncology bGerhard-Domagk Institute of Pathology, University Hospital Münster, Münster cInstitute for Experimental Cancer Research in Pediatrics, Goethe-University, Frankfurt dSuabian Children's Cancer Center, Children's Hospital Augsburg, Augsburg, Germany.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CAD.0000000000000256DOI Listing
September 2015

Local control in Ewing sarcoma of the chest wall: results of the EURO-EWING 99 trial.

Ann Surg Oncol 2015 Sep 24;22(9):2853-9. Epub 2015 Jun 24.

Section of Thoracic Surgery and Lung Transplantation, Department of Cardiothoracic Surgery, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1245/s10434-015-4630-0DOI Listing
September 2015

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration.

J Clin Oncol 2015 Sep 24;33(27):3036-46. Epub 2015 Aug 24.

Nathalie Gaspar, Marie-Cecile Le Deley, and Odile Oberlin, Institut Gustave Roussy, Villejuif; Nathalie Gaspar, Marie-Cecile Le Deley, Line Claude, Olivier Delattre, Jean Michon, Perrine Marec-Bérard, and Odile Oberlin, Société Française de Lutte Contre les Cancers et les Leucémies de l'Enfant et de l'Adolescent; Marie-Cecile Le Deley, Paris-Sud University, Le Kremlin-Bicêtre; Line Claude and Perrine Marec-Bérard, Centre Léon-Bérard, Lyon; Olivier Delattre and Jean Michon, Institut Curie, Paris, France; Douglas S. Hawkins, Seattle Children's Hospital, Seattle, WA; Douglas S. Hawkins, Mark L. Bernstein, and Richard B. Womer, Children's Oncology Group; Uta Dirksen and Heribert Juergens, University Hospital Münster, Münster; Uta Dirksen, Michael Paulussen, and Heribert Juergens, Gesellschaft für Pädiatrische Onkologie und Hämatologie; Michael Paulussen, Children's and Adolescents' Hospital, Witten/Herdecke University, Datteln, Germany; Ian J. Lewis, Alder Hey Children's National Health Service (NHS) Foundation Trust, Liverpool; Ian J. Lewis, Robert Grimer, Bernadette Brennan, and Alan W. Craft, Children's Cancer and Leukaemia Group; Robert Grimer, Royal Orthopaedic Hospital, Birmingham; Jeremy Whelan, University College London Hospital NHS Foundation Trust; Ian Judson, Royal Marsden Hospital, London; Bernadette Brennan, Royal Manchester Children's Hospital, Manchester; Alan W. Craft, Royal Victoria Infirmary, Newcastle, United Kingdom; Stefano Ferrari and Piero Picci, Rizzoli Institute, Bologna; Stefano Ferrari, Piero Picci, Roberto Luksch, Italian Sarcoma Group; Roberto Luksch, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy; Heinrich Kovar and Ruth Ladenstein, Children's Cancer Institute, St Anna Kinderkrebsforschung, Wien; Heinrich Kovar and Ruth Ladenstein, Arbeitsgemeinschaft Ambulant Tätiger Pädiatrischer Onkologen und Hämatologen, Vienna, Austria; Jeremy Whelan and Ian Judson, European O

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http://jco.ascopubs.org/content/33/27/3036.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.59.5256
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http://dx.doi.org/10.1200/JCO.2014.59.5256DOI Listing
September 2015

Analysis of the antiproliferative effects of 3-deazaneoplanocin A in combination with standard anticancer agents in rhabdoid tumor cell lines.

Anticancer Drugs 2015 Mar;26(3):301-11

aDepartment of Pediatric Hematology and Oncology, University Children's Hospital Münster bDepartment of General and Visceral Surgery, University Hospital of Münster, Münster cDivision of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg dSwabian Suabian Children's Cancer Center, Children's Hospital Augsburg, Augsburg, Germany.

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http://dx.doi.org/10.1097/CAD.0000000000000181DOI Listing
March 2015

Etoposide and carbo-or cisplatin combination therapy in refractory or relapsed Ewing sarcoma: a large retrospective study.

Pediatr Blood Cancer 2015 Jan 22;62(1):40-4. Epub 2014 Sep 22.

Department of Clinical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pbc.25230DOI Listing
January 2015

Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion.

PLoS One 2014 25;9(3):e93067. Epub 2014 Mar 25.

Gerhard-Domagk-Institute for Pathology, University Hospital Münster, Westfälische Wilhelms-University, Münster, Germany; Department of Pathology, Justus-Liebig-University, Giessen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093067PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965523PMC
November 2014

The value of high-dose chemotherapy in patients with first relapsed Ewing sarcoma.

Pediatr Blood Cancer 2014 Aug 11;61(8):1382-6. Epub 2014 Apr 11.

Department of Pediatric Hematology and Oncology, University Hospital Münster, Westfalian Wilhelms University Münster, Munster, Germany.

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http://doi.wiley.com/10.1002/pbc.25042
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http://dx.doi.org/10.1002/pbc.25042DOI Listing
August 2014

Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function.

Oncol Rep 2014 Aug 13;32(2):845-52. Epub 2014 Jun 13.

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, D-48149 Muenster, Germany.

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http://dx.doi.org/10.3892/or.2014.3269DOI Listing
August 2014

Cyclophosphamide compared with ifosfamide in consolidation treatment of standard-risk Ewing sarcoma: results of the randomized noninferiority Euro-EWING99-R1 trial.

J Clin Oncol 2014 Aug 30;32(23):2440-8. Epub 2014 Jun 30.

Odile Oberlin, Gustave Roussy Institute, Villejuif; Marie-Cécile Le Deley, Université Paris-Sud, Le Kremlin-Bicêtre; Jean Michon, Institut Curie, Paris; Perrine Marec-Bérard, Centre Léon-Bérard, Lyon, France; Michael Paulussen, Vestische Kinder-und Jugendklinik Datteln, Witten/Herdecke University, Datteln; Andreas Ranft, Heribert Juergens, and Uta Dirksen, University Hospital Münster, Münster, Germany; Ian Lewis, Alder Hey Children's National Health Service Foundation Trust, Liverpool; Bernadette Brennan, Royal Manchester Children's Hospital, Manchester; Jeremy Whelan, University College London Hospital National Health Service Foundation Trust; Ian Judson, The Royal Marsden Hospital, London; Keith Wheatley, University of Birmingham, Birmingham; Alan Craft, Royal Victoria Infirmary, Newcastle, United Kingdom; Ruth Ladenstein, St Anna Children's Cancer Research Institute, Vienna, Austria; Henk van den Berg, Emma Children Hospital AMC, Amsterdam, the Netherlands; and Lars Hjorth, Skåne University Hospital, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1200/JCO.2013.54.4833DOI Listing
August 2014

The Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth.

Biol Cell 2013 Nov 18;105(11):535-47. Epub 2013 Sep 18.

Children's Cancer Research Center and Roman Herzog Comprehensive Cancer Center, Laboratory of Functional Genomics and Transplantation Biology, Klinikum rechts der Isar, Technische Universität München, Munich, 80804, Germany.

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http://dx.doi.org/10.1111/boc.201300041DOI Listing
November 2013

Localized Ewing sarcoma of the tibia.

Clin Sarcoma Res 2013 Feb 4;3(1). Epub 2013 Feb 4.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX7HE, UK.

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http://dx.doi.org/10.1186/2045-3329-3-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606613PMC
February 2013

The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease.

Clin Sarcoma Res 2012 Dec 18;2(1):24. Epub 2012 Dec 18.

Department of Pediatrics, Leiden University Medical Center, Albinusdreef 2, 2300, RC, Leiden, the Netherlands.

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http://dx.doi.org/10.1186/2045-3329-2-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549731PMC
December 2012

A Novel Role of IGF1 in Apo2L/TRAIL-Mediated Apoptosis of Ewing Tumor Cells.

Sarcoma 2012 3;2012:782970. Epub 2012 Oct 3.

Institute of Experimental Musculoskeletal Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.

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http://dx.doi.org/10.1155/2012/782970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469244PMC
October 2012

Ewing sarcoma: clinical state-of-the-art.

Pediatr Hematol Oncol 2012 Feb;29(1):1-11

Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.3109/08880018.2011.622034DOI Listing
February 2012

Ewing sarcoma: biology-based therapeutic perspectives.

Pediatr Hematol Oncol 2012 Feb;29(1):12-27

Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.3109/08880018.2011.627582DOI Listing
February 2012

Proximal fibula resection in the treatment of bone tumours.

Int Orthop 2011 Nov 11;35(11):1689-94. Epub 2011 Jan 11.

Department of Orthopaedics and Tumour Orthopaedics, University Hospital of Münster, Albert-Schweitzer-Straße 33, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00264-010-1193-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193948PMC
November 2011

Risk of recurrence and survival after relapse in patients with Ewing sarcoma.

Pediatr Blood Cancer 2011 Oct 25;57(4):549-53. Epub 2011 Mar 25.

Department of Pediatric Hematology and Oncology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/pbc.23040DOI Listing
October 2011

Ewing sarcoma treatment.

Eur J Cancer 2011 Sep;47 Suppl 3:S366-7

Department of Paediatric Haematology and Oncology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1016/S0959-8049(11)70206-4DOI Listing
September 2011

Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.

J Clin Oncol 2010 Jul 14;28(20):3284-91. Epub 2010 Jun 14.

St Anna Children's Hospital, SIRP-CCRI Studies and Statistics on Integrated Research and Projects, Children's Cancer Research Institute, Vienna, Austria.

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http://ascopubs.org/doi/10.1200/JCO.2009.22.9864
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http://dx.doi.org/10.1200/JCO.2009.22.9864DOI Listing
July 2010

Approaching Ewing sarcoma.

Future Oncol 2010 Jul;6(7):1155-62

Pediatric Hematology & Oncology, Albert-Schweitzer Str. 33, 48149 Münster, Germany.

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http://dx.doi.org/10.2217/fon.10.76DOI Listing
July 2010

Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor.

BMC Cancer 2010 Jul 16;10:372. Epub 2010 Jul 16.

Botnar Research Centre, University of Oxford, Nuffield Orthopaedic Centre, Oxford, OX3 7LD, UK.

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http://dx.doi.org/10.1186/1471-2407-10-372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918574PMC
July 2010

The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES).

Cancer 2010 Jan;116(2):443-50

University Children's Hospital Muenster, Department of Pediatric Hematology and Oncology, 48149 Muenster, Germany.

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http://doi.wiley.com/10.1002/cncr.24740
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http://dx.doi.org/10.1002/cncr.24740DOI Listing
January 2010

Radiation toxicity following busulfan/melphalan high-dose chemotherapy in the EURO-EWING-99-trial: review of GPOH data.

Strahlenther Onkol 2009 Aug;185 Suppl 2:21-2

Department of Radiotherapy at the University Hospital of Münster, Münster, Germany.

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http://link.springer.com/10.1007/s00066-009-1009-9
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http://dx.doi.org/10.1007/s00066-009-1009-9DOI Listing
August 2009

Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2.

Cell Cycle 2009 Jul 5;8(13):1991-6. Epub 2009 Jul 5.

Laboratory for Functional Genomics and Transplantation Biology, Department of Pediatrics and Children's Cancer Research Center, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.4161/cc.8.13.8929DOI Listing
July 2009

Ewing's tumors over the age of 40: a retrospective analysis of 47 patients treated according to the International Clinical Trials EICESS 92 and EURO-E.W.I.N.G. 99.

Onkologie 2008 Dec 20;31(12):657-63. Epub 2008 Nov 20.

Dept. of Pediatric Hematology and Oncology, University Children's Hospital, Munster, Germany.

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http://dx.doi.org/10.1159/000165361DOI Listing
December 2008

Ewing tumors in infants.

Pediatr Blood Cancer 2008 Apr;50(4):761-4

Department of Pediatric Oncology, Emma Children Hospital, Academic Medical Center, University of Amsterdamm, The Netherlands.

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http://dx.doi.org/10.1002/pbc.21292DOI Listing
April 2008

Gene therapy of beta(c)-deficient pulmonary alveolar proteinosis (beta(c)-PAP): studies in a murine in vivo model.

Mol Ther 2008 Apr 4;16(4):757-64. Epub 2008 Mar 4.

Department of Internal Medicine (Cancer Research), West German Cancer Center, University of Duisburg-Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1038/mt.2008.7DOI Listing
April 2008

Gene Therapy of βc-Deficient Pulmonary Alveolar Proteinosis (βc-PAP): Studies in a Murine in vivo Model.

Mol Ther 2008 Apr 8;16(4):757-764. Epub 2016 Dec 8.

Department of Internal Medicine (Cancer Research), West German Cancer Center, University of Duisburg-Essen Medical School, Essen, Germany. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S152500161631458
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April 2008

Significant benefit of multimodal imaging: PET/CT compared with PET alone in staging and follow-up of patients with Ewing tumors.

J Nucl Med 2007 Dec 15;48(12):1932-9. Epub 2007 Nov 15.

Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.

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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.107.045286
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http://dx.doi.org/10.2967/jnumed.107.045286DOI Listing
December 2007

Cytotoxicity of treosulfan and busulfan on pediatric tumor cell lines.

Anticancer Drugs 2006 Jul;17(6):657-62

Department of Pediatric Hematology and Oncology, University Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1097/01.cad.0000215059.93437.89DOI Listing
July 2006

Glutathione S transferase theta 1 gene (GSTT1) null genotype is associated with an increased risk for acquired aplastic anemia in children.

Pediatr Res 2004 Mar 17;55(3):466-71. Epub 2003 Dec 17.

Department of Pediatric Hematology and Oncology, Childrens Hospital Heinrich Heine-University Medical School, Moorenstr. 5, 40225 Duesseldorf, Germany.

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http://www.nature.com/doifinder/10.1203/01.PDR.0000111201.56
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http://dx.doi.org/10.1203/01.PDR.0000111201.56182.FEDOI Listing
March 2004