Publications by authors named "Uschi Leeser"

10Publications

The Cdkn1a Mouse as a Tool to Study p53-Mediated Tumor Suppression.

Cell Rep 2018 10;25(4):1027-1039.e6

Department I of Internal Medicine, University Hospital Cologne, Weyertal 115b, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), University of Cologne, Joseph Stelzmann Straße 26, 50931 Cologne, Germany; Center for Molecular Medicine, University Hospital Cologne, Robert Koch Straße 21, 50931 Cologne. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183153
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http://dx.doi.org/10.1016/j.celrep.2018.09.079DOI Listing
October 2018

Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma.

Cancer Res 2017 06 31;77(11):3040-3056. Epub 2017 Mar 31.

Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-3398DOI Listing
June 2017

Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression.

PLoS One 2015 20;10(5):e0125745. Epub 2015 May 20.

Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125745PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439058PMC
February 2016

A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC.

Cancer Discov 2014 May 20;4(5):592-605. Epub 2014 Feb 20.

1Department of Translational Genomics; 2Institute of Pathology; 3Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne; 4Department of Internal Medicine, University Hospital of Cologne, Cologne, Germany; and 5Michael F. Price Center, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0907DOI Listing
May 2014

Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells.

Biochim Biophys Acta 2011 May 24;1812(5):573-80. Epub 2011 Feb 24.

Department of Internal Medicine II, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.1016/j.bbadis.2011.02.006DOI Listing
May 2011

Neuronal insulin receptor substrate 2 (IRS2) expression is regulated by ZBP89 and SP1 binding to the IRS2 promoter.

J Endocrinol 2010 Feb 29;204(2):199-208. Epub 2009 Oct 29.

Department of Internal Medicine II, Center for Molecular Medicine Cologne (CMMC) and Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, 50937 Cologne, Germany.

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https://joe.bioscientifica.com/view/journals/joe/204/2/199.x
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http://dx.doi.org/10.1677/JOE-09-0266DOI Listing
February 2010

Transcription factor FBI-1 acts as a dual regulator in adipogenesis by coordinated regulation of cyclin-A and E2F-4.

J Mol Med (Berl) 2008 May 27;86(5):597-608. Epub 2008 Mar 27.

Department of Internal Medicine II and Centre of Molecular Medicine Cologne (CMMC), University of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.1007/s00109-008-0326-2DOI Listing
May 2008

Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.

Diabetes 2005 Dec;54(12):3343-8

Department of Internal Medicine II, LFI 4/061, University of Cologne, Kerpener Str. 62, D-50937 Cologne, Germany.

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http://dx.doi.org/10.2337/diabetes.54.12.3343DOI Listing
December 2005