Ursula Fearon

Ursula Fearon

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Ursula Fearon

Publications by authors named "Ursula Fearon"

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Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis.

EBioMedicine 2019 Sep 26;47:402-413. Epub 2019 Aug 26.

Molecular Rheumatology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland; EULAR Centre for Arthritis and Rheumatic Diseases, Vincent's University Hospital, Dublin Academic Health Care, University College Dublin, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.08.043DOI Listing
September 2019

Performance characteristics and predictors of temporal artery ultrasound for the diagnosis of giant cell arteritis in routine clinical practice in a prospective cohort.

Clin Exp Rheumatol 2019 Mar-Apr;37 Suppl 117(2):72-78. Epub 2019 Jan 4.

Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin Academic Medical Centre, Dublin, Ireland.

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June 2019

Angiogenesis in Inflammatory Arthritis.

Isr Med Assoc J 2019 May;5(21):345-352

Division of Rheumatology, Department of Medicine, University of Debrecen Faculty of Medicine, Debrecen, Hungary.

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May 2019

Interleukin-6 does not upregulate pro-inflammatory cytokine expression in an model of giant cell arteritis.

Rheumatol Adv Pract 2019 6;3(1):rkz011. Epub 2019 May 6.

Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin Academic Medical Centre, Royal College of Surgeons, Ireland.

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http://dx.doi.org/10.1093/rap/rkz011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649906PMC
May 2019

Association of synovial tissue polyfunctional T-cells with DAPSA in psoriatic arthritis.

Ann Rheum Dis 2019 Mar 9;78(3):350-354. Epub 2019 Jan 9.

Molecular Rheumatology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2018-214138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390025PMC
March 2019

Novel gene targets for miRNA146a and miRNA155 in anterior uveitis.

Br J Ophthalmol 2019 02 8;103(2):279-285. Epub 2018 Oct 8.

Department of Ophthalmology, Royal College of Surgeons in Ireland, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3128
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http://dx.doi.org/10.1136/bjophthalmol-2018-312885DOI Listing
February 2019

Autoimmune and angiogenic biomarkers in autoimmune atherosclerosis.

Clin Immunol 2019 Feb 10;199:47-51. Epub 2018 Dec 10.

Division of Rheumatology, Department of Medicine, University of Debrecen, Faculty of Medicine, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.12.011DOI Listing
February 2019

Cell metabolism as a potentially targetable pathway in RA.

Nat Rev Rheumatol 2019 Feb;15(2):70-72

Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/s41584-018-0148-8DOI Listing
February 2019

Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B.

J Autoimmun 2019 Jan 1;96:86-93. Epub 2018 Sep 1.

Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.08.008DOI Listing
January 2019

Ustekinumab for refractory giant cell arteritis: A prospective 52-week trial.

Semin Arthritis Rheum 2018 12 22;48(3):523-528. Epub 2018 Apr 22.

Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin Academic Medical Centre, Elm Park, Dublin 4, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S00490172173080
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http://dx.doi.org/10.1016/j.semarthrit.2018.04.004DOI Listing
December 2018

Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis.

Ann Rheum Dis 2018 12 10;77(12):1815-1824. Epub 2018 Aug 10.

Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital Dublin, Academic Medical Centre, Dublin 4, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2018-213488DOI Listing
December 2018

Hypoxia, oxidative stress and inflammation.

Free Radic Biol Med 2018 09 27;125:15-24. Epub 2018 Mar 27.

The Department of Molecular Rheumatology, Trinity College Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.03.042DOI Listing
September 2018

The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis.

Front Med (Lausanne) 2018 3;5:185. Epub 2018 Aug 3.

Dublin Academic Medical Centre, Centre for Arthritis and Rheumatic Diseases, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.3389/fmed.2018.00185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085449PMC
August 2018

The pathogenesis of psoriatic arthritis.

Lancet 2018 06 1;391(10136):2273-2284. Epub 2018 Jun 1.

Rheumatology EULAR Centre of Excellence, St Vincent's University Hospital and University College Dublin, Dublin, Ireland; Department of Molecular Rheumatology, Trinity Biomedical Science Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1016/S0140-6736(18)30830-4DOI Listing
June 2018

Oxidative stress impairs energy metabolism in primary cells and synovial tissue of patients with rheumatoid arthritis.

Arthritis Res Ther 2018 05 29;20(1):95. Epub 2018 May 29.

Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1186/s13075-018-1592-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972404PMC
May 2018

Response to: ustekinumab inhibits Th1 and Th17 polarisation in a giant-cell arteritis patient by Samson .

Ann Rheum Dis 2018 02 25;77(2):e7. Epub 2017 May 25.

Centre for Arthritis and Rheumatic Diseases, St. Vincent's University Hospital, Dublin Academic Medical Centre, Dublin, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2017-211669DOI Listing
February 2018

Knee joint synovitis: study of correlations and diagnostic performances of ultrasonography compared with histopathology.

RMD Open 2018 8;4(1):e000616. Epub 2018 Feb 8.

The Centre for Arthritis and Rheumatic Diseases, Saint Vincent's University Hospital and Dublin Academic Medical Centre, University College Dublin, Dublin, Ireland.

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2017-00061
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http://dx.doi.org/10.1136/rmdopen-2017-000616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845411PMC
February 2018

Reply.

Arthritis Rheumatol 2017 12 8;69(12):2404-2406. Epub 2017 Nov 8.

Royal College of Surgeons in Ireland, and Beaumont Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.40309DOI Listing
December 2017

Response to: 'Regulatory role of the JAK STAT kinase signalling system on the IL-23/IL-17 cytokine axis in psoriatic arthritis' by Raychaudhuri .

Ann Rheum Dis 2017 10 8;76(10):e37. Epub 2017 Feb 8.

Department of Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2017-211081DOI Listing
October 2017

Synovial tissue research: a state-of-the-art review.

Nat Rev Rheumatol 2017 08 13;13(8):463-475. Epub 2017 Jul 13.

Department of Clinical Immunology &Rheumatology, Amsterdam Rheumatology and Immunology Centre, Academic Medical Centre, University of Amsterdam, Room F4-105, POBox 22700, 1100 DE, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2017.115DOI Listing
August 2017

Cellular and molecular perspectives in rheumatoid arthritis.

Semin Immunopathol 2017 06 15;39(4):343-354. Epub 2017 May 15.

The Department of Molecular Rheumatology, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/s00281-017-0633-1DOI Listing
June 2017

The role of metabolism in the pathogenesis of osteoarthritis.

Nat Rev Rheumatol 2017 May 6;13(5):302-311. Epub 2017 Apr 6.

Department of Molecular Rheumatology, Trinity College Dublin, University of Dublin, College Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/nrrheum.2017.50DOI Listing
May 2017

Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.

J Immunol 2017 03 6;198(6):2249-2259. Epub 2017 Feb 6.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland;

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http://dx.doi.org/10.4049/jimmunol.1600737DOI Listing
March 2017

Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis.

Sci Rep 2017 02 22;7:43165. Epub 2017 Feb 22.

Molecular Rheumatology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/srep43165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320554PMC
February 2017

Ustekinumab for the treatment of refractory giant cell arteritis.

Ann Rheum Dis 2016 08 3;75(8):1578-9. Epub 2016 May 3.

Department of Rheumatology, Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin Academic Medical Centre, Dublin 4, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2016-209351DOI Listing
August 2016

Acute serum amyloid A is an endogenous TLR2 ligand that mediates inflammatory and angiogenic mechanisms.

Ann Rheum Dis 2016 07 19;75(7):1392-8. Epub 2015 Aug 19.

Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre and Conway Institute of Biomolecular and Biomedical Research, Dublin 4, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2015-207655DOI Listing
July 2016

Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis.

Nat Rev Rheumatol 2016 07 26;12(7):385-97. Epub 2016 May 26.

The Centre for Arthritis and Rheumatic Disease, Dublin Academic Medical Centre, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

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http://dx.doi.org/10.1038/nrrheum.2016.69DOI Listing
July 2016

A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-α treatment of psoriatic arthritis.

Proteomics Clin Appl 2016 06 28;10(6):645-62. Epub 2015 Sep 28.

School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1002/prca.201500051DOI Listing
June 2016

What makes psoriatic and rheumatoid arthritis so different?

RMD Open 2015 28;1(1):e000025. Epub 2015 Apr 28.

The Centre for Arthritis and Rheumatic Diseases, EULAR Centre of Excellence, St Vincent's University Hospital, Dublin Academic Medical Centre , Dublin , Ireland ; The Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.1136/rmdopen-2014-000025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613157PMC
October 2015

Regulation of Inflammation and Angiogenesis in Giant Cell Arteritis by Acute-Phase Serum Amyloid A.

Arthritis Rheumatol 2015 Sep;67(9):2447-56

St. Vincent's University Hospital and Dublin Academic Medical Centre, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.39217DOI Listing
September 2015

C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis.

Proc Natl Acad Sci U S A 2015 Sep 27;112(37):11618-23. Epub 2015 Aug 27.

Academic Unit of Rheumatology, University of Sheffield, Sheffield S10 2RX, United Kingdom; Department of Rheumatology, Dublin Academic Medical Centre and the Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin D04 W6F6, Ireland;

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http://dx.doi.org/10.1073/pnas.1501947112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577169PMC
September 2015

Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity.

J Immunol 2015 Jul 10;195(2):528-40. Epub 2015 Jun 10.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland; School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1402990
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http://dx.doi.org/10.4049/jimmunol.1402990DOI Listing
July 2015

Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis.

Ann Rheum Dis 2015 Jun 13;74(6):1275-83. Epub 2014 Feb 13.

Translational Research Group, Dublin Academic Medical Centre, St Vincent's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2013-204105DOI Listing
June 2015

Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis.

Arthritis Res Ther 2015 Jun 9;17:153. Epub 2015 Jun 9.

Department of Rheumatology, St. Vincent's University Hospital, Elm Park, Dublin Academic Health Care and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/s13075-015-0664-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495696PMC
June 2015

Redox-mediated angiogenesis in the hypoxic joint of inflammatory arthritis.

Arthritis Rheumatol 2014 Dec;66(12):3300-10

Dublin Academic Medical Centre and St. Vincent's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.38822DOI Listing
December 2014

Key Challenges in Rheumatic and Musculoskeletal Disease Translational Research.

EBioMedicine 2014 Dec 18;1(2-3):95-6. Epub 2014 Nov 18.

St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.ebiom.2014.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457412PMC
December 2014

Hypoxia: how does the monocyte-macrophage system respond to changes in oxygen availability?

J Leukoc Biol 2014 Feb 29;95(2):233-41. Epub 2013 Oct 29.

2.Charité-Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1189/jlb.1212627DOI Listing
February 2014

Notch-1 mediates endothelial cell activation and invasion in psoriasis.

Exp Dermatol 2014 Feb;23(2):113-8

Department of Rheumatology, Dublin Academic Medical Centre and the Conway Institute of Biomolecular and Biomedical Research, UCD, Dublin 4, Ireland.

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http://dx.doi.org/10.1111/exd.12306DOI Listing
February 2014

Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity.

Am J Pathol 2013 Oct 6;183(4):1243-1257. Epub 2013 Aug 6.

UCD Veterinary Sciences Centre, University College Dublin, Belfield, Ireland; Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.06.029DOI Listing
October 2013

Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2.

Ann Rheum Dis 2013 Jun 17;72(6):1080-8. Epub 2012 Nov 17.

Department of Rheumatology, Translational Research Group, Dublin Academic Medical Centre, St Vincent's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2012-201978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664379PMC
June 2013

Macrophages in synovial inflammation.

Front Immunol 2011 10;2:52. Epub 2011 Oct 10.

School of Medicine and Medical Sciences, University College Dublin Conway Institute Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2011.00052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342259PMC
August 2012

Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis.

Arthritis Rheum 2012 Jul;64(7):2104-13

Dublin Academic Medical Centre, St. Vincent's University Hospital, and University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.34397DOI Listing
July 2012

Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy.

Arthritis Rheum 2012 Apr 10;64(4):1035-45. Epub 2011 Nov 10.

St. Vincent's University Hospital, Dublin Academic Medical Centre, The Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.33455DOI Listing
April 2012

Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis.

Ann Rheum Dis 2012 Apr 25;71(4):582-8. Epub 2011 Nov 25.

Translation Rheumatology Research Group, Dublin Academic Medical Centre, St Vincent’s University Hospital, Elm Park, Ireland.

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http://dx.doi.org/10.1136/annrheumdis-2011-200245DOI Listing
April 2012

Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis.

PLoS One 2011 17;6(8):e23540. Epub 2011 Aug 17.

Department of Rheumatology, Dublin Academic Medical Centre and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023540PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157402PMC
February 2012

Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement.

Arthritis Rheum 2011 Nov;63(11):3263-73

Dublin Academic Medical Centre and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.30582DOI Listing
November 2011

Interleukin-27: a master regulator in inflammation.

Authors:
Ursula Fearon

Arthritis Rheum 2011 Aug;63(8):2157-60

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http://dx.doi.org/10.1002/art.30322DOI Listing
August 2011

Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis.

Arthritis Rheum 2011 Aug;63(8):2172-82

Dublin Academic Medical Centre, St. Vincent's University Hospital, and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.30395DOI Listing
August 2011

Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis.

Arthritis Res Ther 2011 Jul 25;13(4):R121. Epub 2011 Jul 25.

Translation Rheumatology Research Group, Dublin Academic Medical Centre, The Conway Institute of Biomolecular and Biomedical Research, St. Vincent’s University Hospital, Elm Park, Dublin 4, Ireland.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239359PMC
July 2011

Tumor necrosis factor blocking therapy alters joint inflammation and hypoxia.

Arthritis Rheum 2011 Apr;63(4):923-32

Dublin Academic Medical Centre, The Conway Institute for Biomolecular and Biomedical Research, University College, Dublin, Ireland.

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http://doi.wiley.com/10.1002/art.30221
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http://dx.doi.org/10.1002/art.30221DOI Listing
April 2011

Is remission a more realistic goal in psoriatic arthritis?

Ther Adv Musculoskelet Dis 2011 Feb;3(1):3-7

Dublin Academic Medical Centre, Department of Rheumatology, Bone and Joint Unit, St Vincent's University Hospital and the Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland.

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http://dx.doi.org/10.1177/1759720X10389847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383536PMC
February 2011

Remission in psoriatic arthritis: is it possible and how can it be predicted?

Arthritis Res Ther 2010 18;12(3):R94. Epub 2010 May 18.

Department of Rheumatology, Dublin Academic Medical Centre, St Vincent's University Hospital, and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Elm Park, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/ar3021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911878PMC
November 2010

Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint.

Ann Rheum Dis 2010 Jun 24;69(6):1172-8. Epub 2009 Aug 24.

Department of Rheumatology, Dublin Academic Health Care, St Vincent's University Hospital and The Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2009.111211
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http://dx.doi.org/10.1136/ard.2009.111211DOI Listing
June 2010

A role for the high-density lipoprotein receptor SR-B1 in synovial inflammation via serum amyloid-A.

Am J Pathol 2010 Apr 19;176(4):1999-2008. Epub 2010 Mar 19.

Education and Research Centre, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

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http://dx.doi.org/10.2353/ajpath.2010.090014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843487PMC
April 2010

Angiogenesis and blood vessel stability in inflammatory arthritis.

Arthritis Rheum 2010 Mar;62(3):711-21

Dublin Academic Health Care, St. Vincent's University Hospital and The Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland.

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http://doi.wiley.com/10.1002/art.27287
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http://dx.doi.org/10.1002/art.27287DOI Listing
March 2010

Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies.

Arthritis Res Ther 2009 23;11(4):R113. Epub 2009 Jul 23.

Department of Rheumatology, St, Vincent's University Hospital, Dublin Academic Healthcare and The Conway Institute of Biomolecular and Biomedical Research, Elm Park, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/ar2772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745795PMC
December 2009

Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway.

Antioxid Redox Signal 2009 Sep;11(9):2057-64

UCD Conway Institute, University College Dublin, Belfield, Ireland.

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http://dx.doi.org/10.1089/ars.2008.2400DOI Listing
September 2009

Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition.

J Invest Dermatol 2008 Feb 2;128(2):300-10. Epub 2007 Aug 2.

College of Life Sciences, UCD Veterinary Sciences Centre, Dublin, Ireland.

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http://dx.doi.org/10.1038/sj.jid.5701023DOI Listing
February 2008

Angiogenesis in arthritis: methodological and analytical details.

Methods Mol Med 2007 ;135:343-57

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December 2007

Inhibition of angiogenic pathways in rheumatoid arthritis: potential for therapeutic targeting.

Best Pract Res Clin Rheumatol 2006 Oct;20(5):941-7

Department of Rheumatology, St Vincent's University Hospital and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.berh.2006.05.004DOI Listing
October 2006

Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures.

Arthritis Rheum 2006 Oct;54(10):3152-62

St. Vincent's University Hospital and the Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland.

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http://dx.doi.org/10.1002/art.22161DOI Listing
October 2006

Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy.

J Am Acad Dermatol 2006 Jun 20;54(6):1003-12. Epub 2006 Mar 20.

Department of Rheumatology, St Vincent's University Hospital, Conway Institute of Molecular Medicine, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jaad.2006.01.038DOI Listing
June 2006

Angiogenesis in psoriasis and psoriatic arthritis: clues to disease pathogenesis.

Curr Rheumatol Rep 2005 Aug;7(4):325-9

Department of Rheumatology, St. Vincent's University Hospital and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.

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August 2005

Angiopoietins, growth factors, and vascular morphology in early arthritis.

J Rheumatol 2003 Feb;30(2):260-8

Rheumatology Rehabilitation Research Unit and the Molecular Medicine Unit, University of Leeds, Leeds, UK.

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February 2003