Urban Lendahl

Urban Lendahl

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Urban Lendahl

Publications by authors named "Urban Lendahl"

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Notch signalling regulates epibranchial placode patterning and segregation.

Development 2020 Feb 17;147(4). Epub 2020 Feb 17.

School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China

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http://dx.doi.org/10.1242/dev.183665DOI Listing
February 2020

The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria.

J Biol Chem 2019 Nov 18;294(46):17262-17277. Epub 2019 Sep 18.

Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden

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http://dx.doi.org/10.1074/jbc.RA119.008202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873174PMC
November 2019

Emerging links between cerebrovascular and neurodegenerative diseases-a special role for pericytes.

EMBO Rep 2019 11 16;20(11):e48070. Epub 2019 Oct 16.

Integrated Cardio Metabolic Centre (ICMC), Huddinge, Sweden.

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http://dx.doi.org/10.15252/embr.201948070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831996PMC
November 2019

Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.

Matrix Biol 2019 08 28;81:107-121. Epub 2018 Nov 28.

Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.11.007DOI Listing
August 2019

Mouse Models for Diseases in the Cholangiocyte Lineage.

Methods Mol Biol 2019 ;1981:203-236

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-9420-5_14DOI Listing
August 2019

Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery.

EMBO J 2019 04 6;38(8). Epub 2019 Mar 6.

Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden

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http://dx.doi.org/10.15252/embj.201899748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463211PMC
April 2019

Role of NOTCH3 Mutations in the Cerebral Small Vessel Disease Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.

Stroke 2018 11;49(11):2793-2800

From the Department of Neurobiology, Care Sciences, and Society (K.C., H.K.), Karolinska Institutet Stockholm, Sweden.

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http://dx.doi.org/10.1161/STROKEAHA.118.021560DOI Listing
November 2018

Notch and Wnt Dysregulation and Its Relevance for Breast Cancer and Tumor Initiation.

Biomedicines 2018 Nov 1;6(4). Epub 2018 Nov 1.

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.3390/biomedicines6040101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315509PMC
November 2018

Corrigendum to "Cholangiopathies - Towards a molecular understanding" [EBioMedicine 35 (2018) 381-393].

EBioMedicine 2018 10 9;36:564. Epub 2018 Oct 9.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden; Department of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.09.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197698PMC
October 2018

Changing master regulator without reprogramming.

Exp Cell Res 2018 09 20;370(2):189. Epub 2018 Jun 20.

Karolinska Institute Department of Cell and Molecular Biology Biomedicum, 17177 Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144827183035
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http://dx.doi.org/10.1016/j.yexcr.2018.06.021DOI Listing
September 2018

Cholangiopathies - Towards a molecular understanding.

EBioMedicine 2018 Sep 17;35:381-393. Epub 2018 Sep 17.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden; Department of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161480PMC
September 2018

Introduction.

Authors:
Urban Lendahl

Exp Cell Res 2017 11;360(1)

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http://dx.doi.org/10.1016/j.yexcr.2017.10.001DOI Listing
November 2017

An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.

Elife 2017 11 15;6. Epub 2017 Nov 15.

School of Biomedical sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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https://elifesciences.org/articles/30126
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http://dx.doi.org/10.7554/eLife.30126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705218PMC
November 2017

Notch Signaling in Development, Tissue Homeostasis, and Disease.

Physiol Rev 2017 10;97(4):1235-1294

Department of Discovery Oncology, Genentech Inc., DNA Way, South San Francisco, California; and Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1152/physrev.00005.2017DOI Listing
October 2017

The interplay between the cellular hypoxic response and Notch signaling.

Exp Cell Res 2017 07 26;356(2):146-151. Epub 2017 Apr 26.

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden; Department of Cell Biology, Åbo Akademi University, FI-20520 Turku, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.04.030DOI Listing
July 2017

Lorenz Poellinger MD, PhD (1957-2016).

Authors:
Urban Lendahl

Cell Death Differ 2017 04;24(4):571

Department Cell and Molecular Biology, Karolinska Institute, von Eulers vag 3, Stockholm SE-17177, Sweden.

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http://www.nature.com/doifinder/10.1038/cdd.2017.13
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http://dx.doi.org/10.1038/cdd.2017.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384026PMC
April 2017

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff.

Sci Rep 2017 04 13;7(1):880. Epub 2017 Apr 13.

Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-017-00853-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429825PMC
April 2017

Endogenous APP accumulates in synapses after BACE1 inhibition.

Neurosci Res 2016 Aug 22;109:9-15. Epub 2016 Feb 22.

Department of Neuroscience, Karolinska Institutet, S-171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2016.02.002DOI Listing
August 2016

Notch -- a goldilocks signaling pathway in disease and cancer therapy.

Discov Med 2016 03;21(115):189-96

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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March 2016

Decoding breast cancer tissue-stroma interactions using species-specific sequencing.

Breast Cancer Res 2015 Aug 13;17:109. Epub 2015 Aug 13.

Department of Cell and Molecular Biology, Karolinska Institutet, von Eulers väg 3, SE-17177, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13058-015-0616-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534116PMC
August 2015

Frequency and distribution of Notch mutations in tumor cell lines.

BMC Cancer 2015 Apr 25;15:311. Epub 2015 Apr 25.

Department of Cell and Molecular Biology, SE-171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12885-015-1278-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430925PMC
April 2015

Notch3 is necessary for blood vessel integrity in the central nervous system.

Arterioscler Thromb Vasc Biol 2015 Feb 4;35(2):409-20. Epub 2014 Dec 4.

From the Department of Cell and Molecular Biology (T.H., S.J., U.L.) and Department of Medical Biochemistry and Biophysics, Division of Vascular Biology (C.B., E.R.), Karolinska Institute, Stockholm, Sweden; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden (A.K., L.H., E.R., M.A.M., C.B.); EM Unit, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden (B.R.J.); and Octapharma AB, Stockholm, Sweden (E.W.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304849DOI Listing
February 2015

Cell surface antigen profiling using a novel type of antibody array immobilised to plasma ion-implanted polycarbonate.

Cell Mol Life Sci 2014 Oct 13;71(19):3841-57. Epub 2014 Mar 13.

Department of Cell and Molecular Biology, Karolinska Institutet, 171 77, Stockholm, Sweden,

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http://dx.doi.org/10.1007/s00018-014-1595-2DOI Listing
October 2014

Therapeutic modulation of Notch signalling--are we there yet?

Nat Rev Drug Discov 2014 May;13(5):357-78

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1038/nrd4252DOI Listing
May 2014

PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner.

Cell Res 2014 Apr 25;24(4):433-50. Epub 2014 Mar 25.

1] Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, 20520 Turku, Finland [2] Department of Biosciences, Åbo Akademi University, 20520 Turku, Finland [3] Department of Biomedical Engineering, Technical University of Eindhoven, 2612 Eindhoven, The Netherlands.

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http://dx.doi.org/10.1038/cr.2014.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975507PMC
April 2014

Notch signaling maintains neural rosette polarity.

PLoS One 2013 10;8(5):e62959. Epub 2013 May 10.

Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062959PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651093PMC
December 2013

The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics.

Exp Cell Res 2013 Nov 20;319(18):2893-904. Epub 2013 Jul 20.

Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2013.07.010DOI Listing
November 2013

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling.

Stem Cells Dev 2013 May 12;22(9):1360-9. Epub 2013 Feb 12.

Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Huddinge, Sweden.

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http://dx.doi.org/10.1089/scd.2012.0259DOI Listing
May 2013

A critical role for Sox9 in notch-induced astrogliogenesis and stem cell maintenance.

Stem Cells 2013 Apr;31(4):741-51

Department of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1002/stem.1320DOI Listing
April 2013

Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates.

Cell Mol Life Sci 2013 Mar 18;70(6):951-76. Epub 2012 Jul 18.

Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, 171 76, Stockholm, Sweden,

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http://link.springer.com/10.1007/s00018-012-1066-6
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http://dx.doi.org/10.1007/s00018-012-1066-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578726PMC
March 2013

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.

Proc Natl Acad Sci U S A 2011 Nov 7;108(46):18814-9. Epub 2011 Nov 7.

Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, FI-20521 Turku, Finland.

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http://dx.doi.org/10.1073/pnas.1104943108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219154PMC
November 2011

Notch signaling: simplicity in design, versatility in function.

Development 2011 Sep;138(17):3593-612

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1242/dev.063610DOI Listing
September 2011

Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling.

Biochem Biophys Res Commun 2011 Sep 27;413(3):426-31. Epub 2011 Aug 27.

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2011.08.108DOI Listing
September 2011

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.

EMBO J 2011 Jun 24;30(14):2762-78. Epub 2011 Jun 24.

Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1038/emboj.2011.198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160255PMC
June 2011

Modelling cell lineage using a meta-Boolean tree model with a relation to gene regulatory networks.

J Theor Biol 2011 Jan 12;268(1):62-76. Epub 2010 Oct 12.

Department of Electrical Engineering, Linköping University, Sweden.

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http://dx.doi.org/10.1016/j.jtbi.2010.10.003DOI Listing
January 2011

Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells.

Dev Biol 2010 Dec 29;348(2):153-66. Epub 2010 Sep 29.

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ydbio.2010.09.018DOI Listing
December 2010

Control of Notch-ligand endocytosis by ligand-receptor interaction.

J Cell Sci 2010 Sep;123(Pt 17):2931-42

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1242/jcs.073239DOI Listing
September 2010

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells.

Exp Cell Res 2010 May 23;316(9):1610-24. Epub 2009 Dec 23.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2009.12.012DOI Listing
May 2010

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression.

Development 2010 Feb;137(3):437-45

Department of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1242/dev.036806DOI Listing
February 2010

Evidence for dimeric BACE-mediated APP processing.

Biochem Biophys Res Commun 2010 Feb 25;393(1):21-7. Epub 2010 Jan 25.

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2010.01.064DOI Listing
February 2010

Generating specificity and diversity in the transcriptional response to hypoxia.

Nat Rev Genet 2009 Dec 3;10(12):821-32. Epub 2009 Nov 3.

Department of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://search.proquest.com/openview/8791322b9c058047553b93f9
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http://dx.doi.org/10.1038/nrg2665DOI Listing
December 2009

YB-1 acts as a ligand for Notch-3 receptors and modulates receptor activation.

J Biol Chem 2009 Sep 29;284(39):26928-40. Epub 2009 Jul 29.

Department of Nephrology and Clinical Immunology, University Hospital RWTH-Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany.

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http://dx.doi.org/10.1074/jbc.M109.046599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785380PMC
September 2009

The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation.

J Cell Sci 2009 Jul;122(Pt 13):2252-62

Department of Oncology-Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.038513
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http://dx.doi.org/10.1242/jcs.038513DOI Listing
July 2009

Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms.

Curr Opin Genet Dev 2008 Oct 4;18(5):449-54. Epub 2008 Sep 4.

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, von Eulers väg 3, SE-171 77 Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S0959437X0800092
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http://dx.doi.org/10.1016/j.gde.2008.07.013DOI Listing
October 2008

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.

Circ Res 2008 Jun 15;102(12):1483-91. Epub 2008 May 15.

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.167965DOI Listing
June 2008

[Dedifferentiation of specialized cells. New way open for cell therapy and regenerative medicine].

Authors:
Urban Lendahl

Lakartidningen 2008 May 14-20;105(20):1492-4

Institutionen för cell- och molekylärbiologi, Karolinska institutet, Solna.

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June 2008

Ion fluxes and neurotransmitters signaling in neural development.

Curr Opin Neurobiol 2008 Jun;18(3):232-6

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S095943880800053
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http://dx.doi.org/10.1016/j.conb.2008.06.001DOI Listing
June 2008

SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural progenitor differentiation.

Development 2008 May 16;135(10):1843-51. Epub 2008 Apr 16.

Ludwig Institute for Cancer Research, Karolinska Institute, Box 240, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1242/dev.020180DOI Listing
May 2008

Notch signaling mediates hypoxia-induced tumor cell migration and invasion.

Proc Natl Acad Sci U S A 2008 Apr 21;105(17):6392-7. Epub 2008 Apr 21.

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.0802047105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359811PMC
April 2008

Modulation of vascular gene expression by hypoxia.

Curr Opin Lipidol 2007 Oct;18(5):508-14

Department of Cancer Biology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MOL.0b013e3282efe49dDOI Listing
October 2007

Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines.

Exp Cell Res 2007 Aug 5;313(14):3141-52. Epub 2007 May 5.

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska, Institute, von Eulers väg 3, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2007.04.027DOI Listing
August 2007

High levels of Notch signaling down-regulate Numb and Numblike.

J Cell Biol 2006 Nov;175(4):535-40

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1083/jcb.200602009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064589PMC
November 2006

Recording Notch signaling in real time.

Dev Neurosci 2006 ;28(1-2):118-27

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000090758DOI Listing
May 2006

Notch signaling and its integration with other signaling mechanisms.

Regen Med 2006 Mar;1(2):195-205

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.2217/17460751.1.2.195DOI Listing
March 2006

gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.

J Neurochem 2005 Nov 31;95(3):880-90. Epub 2005 Aug 31.

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03415.xDOI Listing
November 2005

Hypoxia requires notch signaling to maintain the undifferentiated cell state.

Dev Cell 2005 Nov;9(5):617-28

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.devcel.2005.09.010DOI Listing
November 2005

A nine-transmembrane domain topology for presenilin 1.

J Biol Chem 2005 Oct 25;280(42):35352-60. Epub 2005 Jul 25.

Department of Neurotec, Division of Experimental Geriatrics, Karolinska Institutet, Novum, SE-141 86 Huddinge, Sweden.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M507217200
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http://dx.doi.org/10.1074/jbc.M507217200DOI Listing
October 2005

Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch.

J Neurochem 2005 Mar;92(5):1010-20

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02926.xDOI Listing
March 2005

Notch signaling in development and disease.

Semin Cancer Biol 2004 Oct;14(5):320-8

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm SE-171 77, Sweden.

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http://dx.doi.org/10.1016/j.semcancer.2004.04.011DOI Listing
October 2004

Nestin expression is lost in a neural stem cell line through a mechanism involving the proteasome and Notch signalling.

Brain Res Dev Brain Res 2004 Jul;151(1-2):13-23

Department of Neuroscience, Institute of Psychiatry, PO39, 1 Windsor Walk, Denmark Hill, London, UK.

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http://dx.doi.org/10.1016/j.devbrainres.2004.03.018DOI Listing
July 2004

Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.

J Biol Chem 2004 Jun 29;279(23):23925-32. Epub 2004 Mar 29.

Department of Neurotec, Division of Experimental Geriatrics, Karolinska Institutet, Novum, SE-141 86 Huddinge, Sweden.

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http://dx.doi.org/10.1074/jbc.M401277200DOI Listing
June 2004

Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin.

J Biol Chem 2004 Apr 14;279(16):16744-53. Epub 2004 Jan 14.

Department of Neurotec, Karolinska Institutet, Section for Experimental Geriatrics, Novum, SE-141 86 Huddinge, Sweden.

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http://dx.doi.org/10.1074/jbc.M313999200DOI Listing
April 2004

Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors.

Exp Cell Res 2004 Jan;292(1):21-8

Department of Pathology, Göteborg University, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2003.09.007DOI Listing
January 2004

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

Development 2003 Dec;130(24):6089-99

Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1242/dev.00834DOI Listing
December 2003

Role of Islet1 in the patterning of murine dentition.

Development 2003 Sep;130(18):4451-60

GKT Dental Institute, Kings College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1242/dev.00631DOI Listing
September 2003

Notch2 protein distribution in human teeth under normal and pathological conditions.

Exp Cell Res 2003 Jan;282(2):101-9

Laboratoire de Biologie Moléculaire et Cellulaire, UMR 5665 CNRS/ENS Lyon, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, France.

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http://dx.doi.org/10.1016/s0014-4827(02)00012-5DOI Listing
January 2003

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

Proc Natl Acad Sci U S A 2002 Dec 13;99(26):17119-24. Epub 2002 Dec 13.

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, von Eulers väg 3, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.252624099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139279PMC
December 2002

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro.

Mol Cell Biol 2002 Nov;22(22):7812-9

Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, New York 10021, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134732PMC
http://dx.doi.org/10.1128/mcb.22.22.7812-7819.2002DOI Listing
November 2002

[Sydney Brenner, Robert Horvitz and John Sulston. Winners of the 2002 Nobel Prize in medicine or physiology. Genetic regulation of organ development and programmed cell death].

Lakartidningen 2002 Oct;99(41):4026-32

Institutionen för cell- och molekylärbiologi, Karolinska institutet, Stockholm.

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October 2002

Nestin enhancer requirements for expression in normal and injured adult CNS.

J Neurosci Res 2002 Sep;69(6):784-94

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/jnr.10376
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http://dx.doi.org/10.1002/jnr.10376DOI Listing
September 2002

Mouse Notch 3 expression in the pre- and postnatal brain: relationship to the stroke and dementia syndrome CADASIL.

Exp Cell Res 2002 Aug;278(1):31-44

Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1006/excr.2002.5544DOI Listing
August 2002

Patterns of nestin and other intermediate filament expression distinguish between gastrointestinal stromal tumors, leiomyomas and schwannomas.

APMIS 2002 Jun;110(6):499-507

Department of Pathology, Haartman Institute of the University of Helsinki, Finland.

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http://dx.doi.org/10.1034/j.1600-0463.2002.100608.xDOI Listing
June 2002

Notch receptor cleavage depends on but is not directly executed by presenilins.

Proc Natl Acad Sci U S A 2002 Mar 12;99(6):4014-9. Epub 2002 Mar 12.

Department of Medical Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, Faculty of Medicine, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1073/pnas.052017699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122640PMC
March 2002