Unnur Thorsteinsdottir

Unnur Thorsteinsdottir

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Unnur Thorsteinsdottir

Unnur Thorsteinsdottir

Publications by authors named "Unnur Thorsteinsdottir"

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Authors:
Ioanna Ntalla Lu-Chen Weng James H Cartwright Amelia Weber Hall Gardar Sveinbjornsson Nathan R Tucker Seung Hoan Choi Mark D Chaffin Carolina Roselli Michael R Barnes Borbala Mifsud Helen R Warren Caroline Hayward Jonathan Marten James J Cranley Maria Pina Concas Paolo Gasparini Thibaud Boutin Ivana Kolcic Ozren Polasek Igor Rudan Nathalia M Araujo Maria Fernanda Lima-Costa Antonio Luiz P Ribeiro Renan P Souza Eduardo Tarazona-Santos Vilmantas Giedraitis Erik Ingelsson Anubha Mahajan Andrew P Morris Fabiola Del Greco M Luisa Foco Martin Gögele Andrew A Hicks James P Cook Lars Lind Cecilia M Lindgren Johan Sundström Christopher P Nelson Muhammad B Riaz Nilesh J Samani Gianfranco Sinagra Sheila Ulivi Mika Kähönen Pashupati P Mishra Nina Mononen Kjell Nikus Mark J Caulfield Anna Dominiczak Sandosh Padmanabhan May E Montasser Jeff R O'Connell Kathleen Ryan Alan R Shuldiner Stefanie Aeschbacher David Conen Lorenz Risch Sébastien Thériault Nina Hutri-Kähönen Terho Lehtimäki Leo-Pekka Lyytikäinen Olli T Raitakari Catriona L K Barnes Harry Campbell Peter K Joshi James F Wilson Aaron Isaacs Jan A Kors Cornelia M van Duijn Paul L Huang Vilmundur Gudnason Tamara B Harris Lenore J Launer Albert V Smith Erwin P Bottinger Ruth J F Loos Girish N Nadkarni Michael H Preuss Adolfo Correa Hao Mei James Wilson Thomas Meitinger Martina Müller-Nurasyid Annette Peters Melanie Waldenberger Massimo Mangino Timothy D Spector Michiel Rienstra Yordi J van de Vegte Pim van der Harst Niek Verweij Stefan Kääb Katharina Schramm Moritz F Sinner Konstantin Strauch Michael J Cutler Diane Fatkin Barry London Morten Olesen Dan M Roden M Benjamin Shoemaker J Gustav Smith Mary L Biggs Joshua C Bis Jennifer A Brody Bruce M Psaty Kenneth Rice Nona Sotoodehnia Alessandro De Grandi Christian Fuchsberger Cristian Pattaro Peter P Pramstaller Ian Ford J Wouter Jukema Peter W Macfarlane Stella Trompet Marcus Dörr Stephan B Felix Uwe Völker Stefan Weiss Aki S Havulinna Antti Jula Katri Sääksjärvi Veikko Salomaa Xiuqing Guo Susan R Heckbert Henry J Lin Jerome I Rotter Kent D Taylor Jie Yao Renée de Mutsert Arie C Maan Dennis O Mook-Kanamori Raymond Noordam Francesco Cucca Jun Ding Edward G Lakatta Yong Qian Kirill V Tarasov Daniel Levy Honghuang Lin Christopher H Newton-Cheh Kathryn L Lunetta Alison D Murray David J Porteous Blair H Smith Bruno H Stricker André Uitterlinden Marten E van den Berg Jeffrey Haessler Rebecca D Jackson Charles Kooperberg Ulrike Peters Alexander P Reiner Eric A Whitsel Alvaro Alonso Dan E Arking Eric Boerwinkle Georg B Ehret Elsayed Z Soliman Christy L Avery Stephanie M Gogarten Kathleen F Kerr Cathy C Laurie Amanda A Seyerle Adrienne Stilp Solmaz Assa M Abdullah Said M Yldau van der Ende Pier D Lambiase Michele Orini Julia Ramirez Stefan Van Duijvenboden David O Arnar Daniel F Gudbjartsson Hilma Holm Patrick Sulem Gudmar Thorleifsson Rosa B Thorolfsdottir Unnur Thorsteinsdottir Emelia J Benjamin Andrew Tinker Kari Stefansson Patrick T Ellinor Yalda Jamshidi Steven A Lubitz Patricia B Munroe

Nat Commun 2020 May 21;11(1):2542. Epub 2020 May 21.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/s41467-020-15706-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242331PMC
May 2020

Urinary 2,8-dihydroxyadenine excretion in patients with adenine phosphoribosyltransferase deficiency, carriers and healthy control subjects.

Authors:
Hrafnhildur L Runolfsdottir Runolfur Palsson Unnur A Thorsteinsdottir Olafur S Indridason Inger M Sch Agustsdottir G Steinunn Oddsdottir Margret Thorsteinsdottir Vidar O Edvardsson

Mol Genet Metab 2019 Sep - Oct;128(1-2):144-150. Epub 2019 May 28.

Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland; Children's Medical Center, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2019.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864267PMC
April 2020

Spread of SARS-CoV-2 in the Icelandic Population.

Authors:
Daniel F Gudbjartsson Agnar Helgason Hakon Jonsson Olafur T Magnusson Pall Melsted Gudmundur L Norddahl Jona Saemundsdottir Asgeir Sigurdsson Patrick Sulem Arna B Agustsdottir Berglind Eiriksdottir Run Fridriksdottir Elisabet E Gardarsdottir Gudmundur Georgsson Olafia S Gretarsdottir Kjartan R Gudmundsson Thora R Gunnarsdottir Arnaldur Gylfason Hilma Holm Brynjar O Jensson Aslaug Jonasdottir Frosti Jonsson Kamilla S Josefsdottir Thordur Kristjansson Droplaug N Magnusdottir Louise le Roux Gudrun Sigmundsdottir Gardar Sveinbjornsson Kristin E Sveinsdottir Maney Sveinsdottir Emil A Thorarensen Bjarni Thorbjornsson Arthur Löve Gisli Masson Ingileif Jonsdottir Alma D Möller Thorolfur Gudnason Karl G Kristinsson Unnur Thorsteinsdottir Kari Stefansson

N Engl J Med 2020 Apr 14. Epub 2020 Apr 14.

From deCODE Genetics-Amgen (D.F.G., A.H., H.J., O.T.M., P.M., G.L.N., J.S., A.S., P.S., A.B.A., B.E., R.F., E.E.G., G.G., K.R.G., A.G., H.H., B.O.J., A.J., F.J., T.K., D.N.M., L.R., G. Sveinbjornsson, K.E.S., E.A.T., B.T., G.M., I.J., U.T., K.S.), the School of Engineering and Natural Sciences (D.F.G., P.M.), the Department of Anthropology (A.H.), the Faculty of Medicine, School of Health Sciences (A.L., I.J., K.G.K., U.T., K.S.), and the BioMedical Center of the University of Iceland (K.G.K.), University of Iceland, the Department of Clinical Microbiology, Landspitali-National University Hospital (O.S.G., T.R.G., M.S., A.L., K.G.K.) and the Directorate of Health (K.S.J., G. Sigmundsdottir, A.D.M., T.G.) - all in Reykjavik, Iceland.

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http://dx.doi.org/10.1056/NEJMoa2006100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175425PMC
April 2020

Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis.

Authors:
Gudjon R Oskarsson Asmundur Oddsson Magnus K Magnusson Ragnar P Kristjansson Gisli H Halldorsson Egil Ferkingstad Florian Zink Anna Helgadottir Erna V Ivarsdottir Gudny A Arnadottir Brynjar O Jensson Hildigunnur Katrinardottir Gardar Sveinbjornsson Anna M Kristinsdottir Amy L Lee Jona Saemundsdottir Lilja Stefansdottir Jon K Sigurdsson Olafur B Davidsson Stefania Benonisdottir Aslaug Jonasdottir Adalbjorg Jonasdottir Stefan Jonsson Reynir L Gudmundsson Folkert W Asselbergs Vinicius Tragante Bjarni Gunnarsson Gisli Masson Gudmar Thorleifsson Thorunn Rafnar Hilma Holm Isleifur Olafsson Pall T Onundarson Daniel F Gudbjartsson Gudmundur L Norddahl Unnur Thorsteinsdottir Patrick Sulem Kari Stefansson

Commun Biol 2020 Apr 23;3(1):189. Epub 2020 Apr 23.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s42003-020-0921-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181819PMC
April 2020

Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank.

Authors:
Thorhildur Olafsdottir Gudmar Thorleifsson Patrick Sulem Olafur A Stefansson Helga Medek Karl Olafsson Orri Ingthorsson Valur Gudmundsson Ingileif Jonsdottir Gisli H Halldorsson Ragnar P Kristjansson Michael L Frigge Lilja Stefansdottir Jon K Sigurdsson Asmundur Oddsson Asgeir Sigurdsson Hannes P Eggertsson Pall Melsted Bjarni V Halldorsson Sigrun H Lund Unnur Styrkarsdottir Valgerdur Steinthorsdottir Julius Gudmundsson Hilma Holm Vinicius Tragante Folkert W Asselbergs Unnur Thorsteinsdottir Daniel F Gudbjartsson Kristin Jonsdottir Thorunn Rafnar Kari Stefansson

Commun Biol 2020 Mar 17;3(1):129. Epub 2020 Mar 17.

deCODE Genetics/Amgen, Sturlugata 8, 101, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s42003-020-0857-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078216PMC
March 2020

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood.

Authors:
Sigurgeir Olafsson Kristjan F Alexandersson Johann G K Gizurarson Katrin Hauksdottir Orvar Gunnarsson Karl Olafsson Julius Gudmundsson Simon N Stacey Gardar Sveinbjornsson Jona Saemundsdottir Einar S Bjornsson Sigurdur Olafsson Sigurdur Bjornsson Kjartan B Orvar Arnor Vikingsson Arni J Geirsson Sturla Arinbjarnarson Gyda Bjornsdottir Thorgeir E Thorgeirsson Snaevar Sigurdsson Gisli H Halldorsson Olafur T Magnusson Gisli Masson Hilma Holm Ingileif Jonsdottir Olof Sigurdardottir Gudmundur I Eyjolfsson Isleifur Olafsson Patrick Sulem Unnur Thorsteinsdottir Thorvaldur Jonsson Thorunn Rafnar Daniel F Gudbjartsson Kari Stefansson

Cancer Epidemiol Biomarkers Prev 2020 Jan 30;29(1):225-235. Epub 2019 Oct 30.

deCODE genetics/AMGEN, Reykjavik, Iceland.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-1060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954334PMC
January 2020

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Authors:
Sonia Shah Albert Henry Carolina Roselli Honghuang Lin Garðar Sveinbjörnsson Ghazaleh Fatemifar Åsa K Hedman Jemma B Wilk Michael P Morley Mark D Chaffin Anna Helgadottir Niek Verweij Abbas Dehghan Peter Almgren Charlotte Andersson Krishna G Aragam Johan Ärnlöv Joshua D Backman Mary L Biggs Heather L Bloom Jeffrey Brandimarto Michael R Brown Leonard Buckbinder David J Carey Daniel I Chasman Xing Chen Xu Chen Jonathan Chung William Chutkow James P Cook Graciela E Delgado Spiros Denaxas Alexander S Doney Marcus Dörr Samuel C Dudley Michael E Dunn Gunnar Engström Tõnu Esko Stephan B Felix Chris Finan Ian Ford Mohsen Ghanbari Sahar Ghasemi Vilmantas Giedraitis Franco Giulianini John S Gottdiener Stefan Gross Daníel F Guðbjartsson Rebecca Gutmann Christopher M Haggerty Pim van der Harst Craig L Hyde Erik Ingelsson J Wouter Jukema Maryam Kavousi Kay-Tee Khaw Marcus E Kleber Lars Køber Andrea Koekemoer Claudia Langenberg Lars Lind Cecilia M Lindgren Barry London Luca A Lotta Ruth C Lovering Jian'an Luan Patrik Magnusson Anubha Mahajan Kenneth B Margulies Winfried März Olle Melander Ify R Mordi Thomas Morgan Andrew D Morris Andrew P Morris Alanna C Morrison Michael W Nagle Christopher P Nelson Alexander Niessner Teemu Niiranen Michelle L O'Donoghue Anjali T Owens Colin N A Palmer Helen M Parry Markus Perola Eliana Portilla-Fernandez Bruce M Psaty Kenneth M Rice Paul M Ridker Simon P R Romaine Jerome I Rotter Perttu Salo Veikko Salomaa Jessica van Setten Alaa A Shalaby Diane T Smelser Nicholas L Smith Steen Stender David J Stott Per Svensson Mari-Liis Tammesoo Kent D Taylor Maris Teder-Laving Alexander Teumer Guðmundur Thorgeirsson Unnur Thorsteinsdottir Christian Torp-Pedersen Stella Trompet Benoit Tyl Andre G Uitterlinden Abirami Veluchamy Uwe Völker Adriaan A Voors Xiaosong Wang Nicholas J Wareham Dawn Waterworth Peter E Weeke Raul Weiss Kerri L Wiggins Heming Xing Laura M Yerges-Armstrong Bing Yu Faiez Zannad Jing Hua Zhao Harry Hemingway Nilesh J Samani John J V McMurray Jian Yang Peter M Visscher Christopher Newton-Cheh Anders Malarstig Hilma Holm Steven A Lubitz Naveed Sattar Michael V Holmes Thomas P Cappola Folkert W Asselbergs Aroon D Hingorani Karoline Kuchenbaecker Patrick T Ellinor Chim C Lang Kari Stefansson J Gustav Smith Ramachandran S Vasan Daniel I Swerdlow R Thomas Lumbers

Nat Commun 2020 01 9;11(1):163. Epub 2020 Jan 9.

British Heart Foundation Research Accelerator, University College London, London, UK.

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http://dx.doi.org/10.1038/s41467-019-13690-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952380PMC
January 2020

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis.

Authors:
Thorunn A Olafsdottir Fannar Theodors Kristbjorg Bjarnadottir Unnur Steina Bjornsdottir Arna B Agustsdottir Olafur A Stefansson Erna V Ivarsdottir Jon K Sigurdsson Stefania Benonisdottir Gudmundur I Eyjolfsson David Gislason Thorarinn Gislason Steinunn Guðmundsdóttir Arnaldur Gylfason Bjarni V Halldorsson Gisli H Halldorsson Thorhildur Juliusdottir Anna M Kristinsdottir Dora Ludviksdottir Bjorn R Ludviksson Gisli Masson Kristjan Norland Pall T Onundarson Isleifur Olafsson Olof Sigurdardottir Lilja Stefansdottir Gardar Sveinbjornsson Vinicius Tragante Daniel F Gudbjartsson Gudmar Thorleifsson Patrick Sulem Unnur Thorsteinsdottir Gudmundur L Norddahl Ingileif Jonsdottir Kari Stefansson

Nat Commun 2020 01 20;11(1):393. Epub 2020 Jan 20.

deCODE genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41467-019-14144-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971247PMC
January 2020

Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.

Authors:
Felix Day Tugce Karaderi Michelle R Jones Cindy Meun Chunyan He Alex Drong Peter Kraft Nan Lin Hongyan Huang Linda Broer Reedik Magi Richa Saxena Triin Laisk Margrit Urbanek M Geoffrey Hayes Gudmar Thorleifsson Juan Fernandez-Tajes Anubha Mahajan Benjamin H Mullin Bronwyn G A Stuckey Timothy D Spector Scott G Wilson Mark O Goodarzi Lea Davis Barbara Obermayer-Pietsch André G Uitterlinden Verneri Anttila Benjamin M Neale Marjo-Riitta Jarvelin Bart Fauser Irina Kowalska Jenny A Visser Marianne Andersen Ken Ong Elisabet Stener-Victorin David Ehrmann Richard S Legro Andres Salumets Mark I McCarthy Laure Morin-Papunen Unnur Thorsteinsdottir Kari Stefansson Unnur Styrkarsdottir John R B Perry Andrea Dunaif Joop Laven Steve Franks Cecilia M Lindgren Corrine K Welt

PLoS Genet 2019 Dec 5;15(12):e1008517. Epub 2019 Dec 5.

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http://dx.doi.org/10.1371/journal.pgen.1008517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894746PMC
December 2019

Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes.

Authors:
Daniel F Gudbjartsson Gudmundur Thorgeirsson Patrick Sulem Anna Helgadottir Arnaldur Gylfason Jona Saemundsdottir Eythor Bjornsson Gudmundur L Norddahl Aslaug Jonasdottir Adalbjorg Jonasdottir Hannes P Eggertsson Solveig Gretarsdottir Gudmar Thorleifsson Olafur S Indridason Runolfur Palsson Fridbert Jonasson Ingileif Jonsdottir Gudmundur I Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Ragnar Danielsen Stefan E Matthiasson Snaedis Kristmundsdottir Bjarni V Halldorsson Astradur B Hreidarsson Einar M Valdimarsson Thorarinn Gudnason Rafn Benediktsson Valgerdur Steinthorsdottir Unnur Thorsteinsdottir Hilma Holm Kari Stefansson

J Am Coll Cardiol 2019 12 9;74(24):2982-2994. Epub 2019 Dec 9.

deCODE genetics/Amgen, Reykjavik, Iceland; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.10.019DOI Listing
December 2019

Association of Genetically Predicted Lipid Levels With the Extent of Coronary Atherosclerosis in Icelandic Adults.

Authors:
Eythór Björnsson Guðmar Thorleifsson Anna Helgadóttir Thórarinn Guðnason Tómas Guðbjartsson Karl Andersen Sólveig Grétarsdóttir Ísleifur Ólafsson Vinicius Tragante Ólafur Hreiðar Ólafsson Birna Jónsdóttir Guðmundur I Eyjólfsson Ólöf Sigurðardóttir Guðmundur Thorgeirsson Daníel F Guðbjartsson Unnur Thorsteinsdóttir Hilma Hólm Kári Stefánsson

JAMA Cardiol 2019 Nov 20. Epub 2019 Nov 20.

deCODE genetics/Amgen Inc, Reykjavík, Iceland.

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http://dx.doi.org/10.1001/jamacardio.2019.2946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902100PMC
November 2019

Genetic predisposition to mosaic Y chromosome loss in blood.

Authors:
Deborah J Thompson Giulio Genovese Jonatan Halvardson Jacob C Ulirsch Daniel J Wright Chikashi Terao Olafur B Davidsson Felix R Day Patrick Sulem Yunxuan Jiang Marcus Danielsson Hanna Davies Joe Dennis Malcolm G Dunlop Douglas F Easton Victoria A Fisher Florian Zink Richard S Houlston Martin Ingelsson Siddhartha Kar Nicola D Kerrison Ben Kinnersley Ragnar P Kristjansson Philip J Law Rong Li Chey Loveday Jonas Mattisson Steven A McCarroll Yoshinori Murakami Anna Murray Pawel Olszewski Edyta Rychlicka-Buniowska Robert A Scott Unnur Thorsteinsdottir Ian Tomlinson Behrooz Torabi Moghadam Clare Turnbull Nicholas J Wareham Daniel F Gudbjartsson Yoichiro Kamatani Eva R Hoffmann Steve P Jackson Kari Stefansson Adam Auton Ken K Ong Mitchell J Machiela Po-Ru Loh Jan P Dumanski Stephen J Chanock Lars A Forsberg John R B Perry

Nature 2019 11 20;575(7784):652-657. Epub 2019 Nov 20.

MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/s41586-019-1765-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887549PMC
November 2019

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Authors:
Adrienne Tin Jonathan Marten Victoria L Halperin Kuhns Yong Li Matthias Wuttke Holger Kirsten Karsten B Sieber Chengxiang Qiu Mathias Gorski Zhi Yu Ayush Giri Gardar Sveinbjornsson Man Li Audrey Y Chu Anselm Hoppmann Luke J O'Connor Bram Prins Teresa Nutile Damia Noce Masato Akiyama Massimiliano Cocca Sahar Ghasemi Peter J van der Most Katrin Horn Yizhe Xu Christian Fuchsberger Sanaz Sedaghat Saima Afaq Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Eric Boerwinkle Erwin P Bottinger Thibaud S Boutin Marco Brumat Ralph Burkhardt Eric Campana Archie Campbell Harry Campbell Robert J Carroll Eulalia Catamo John C Chambers Marina Ciullo Maria Pina Concas Josef Coresh Tanguy Corre Daniele Cusi Sala Cinzia Felicita Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Graciela Delgado Ayşe Demirkan Olivier Devuyst Katalin Dittrich Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Michele K Evans Ron T Gansevoort Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Caroline Hayward Andrew A Hicks Edith Hofer Hilma Holm Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Raychel M Lewis Erik Ingelsson Johanna Jakobsdottir Ingileif Jonsdottir Helgi Jonsson Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Masahiro Kanai Shona M Kerr Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Martina La Bianca Leslie A Lange Benjamin Lehne Terho Lehtimäki Jun Liu Markus Loeffler Ruth J F Loos Leo-Pekka Lyytikäinen Reedik Magi Anubha Mahajan Nicholas G Martin Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Andres Metspalu Yuri Milaneschi Christopher J O'Donnell Otis D Wilson J Michael Gaziano Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Martina Müller-Nurasyid Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey R O'Connell Isleifur Olafsson Sandosh Padmanabhan Brenda W J H Penninx Thomas Perls Annette Peters Mario Pirastu Nicola Pirastu Giorgio Pistis Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Michael H Preuss Ton J Rabelink Laura M Raffield Olli T Raitakari Rainer Rettig Myriam Rheinberger Kenneth M Rice Federica Rizzi Antonietta Robino Igor Rudan Alena Krajcoviechova Renata Cifkova Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Erika Salvi Helena Schmidt Reinhold Schmidt Christian M Shaffer Albert V Smith Blair H Smith Cassandra N Spracklen Konstantin Strauch Michael Stumvoll Patrick Sulem Salman M Tajuddin Andrej Teren Joachim Thiery Chris H L Thio Unnur Thorsteinsdottir Daniela Toniolo Anke Tönjes Johanne Tremblay André G Uitterlinden Simona Vaccargiu Pim van der Harst Cornelia M van Duijn Niek Verweij Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger John B Whitfield Sarah H Wild James F Wilson Qiong Yang Weihua Zhang Alan B Zonderman Murielle Bochud James G Wilson Sarah A Pendergrass Kevin Ho Afshin Parsa Peter P Pramstaller Bruce M Psaty Carsten A Böger Harold Snieder Adam S Butterworth Yukinori Okada Todd L Edwards Kari Stefansson Katalin Susztak Markus Scholz Iris M Heid Adriana M Hung Alexander Teumer Cristian Pattaro Owen M Woodward Veronique Vitart Anna Köttgen

Nat Genet 2019 10 2;51(10):1459-1474. Epub 2019 Oct 2.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41588-019-0504-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858555PMC
October 2019

Sequence variants with large effects on cardiac electrophysiology and disease.

Authors:
Kristjan Norland Gardar Sveinbjornsson Rosa B Thorolfsdottir Olafur B Davidsson Vinicius Tragante Sridharan Rajamani Anna Helgadottir Solveig Gretarsdottir Jessica van Setten Folkert W Asselbergs Jon Th Sverrisson Sigurdur S Stephensen Gylfi Oskarsson Emil L Sigurdsson Karl Andersen Ragnar Danielsen Gudmundur Thorgeirsson Unnur Thorsteinsdottir David O Arnar Patrick Sulem Hilma Holm Daniel F Gudbjartsson Kari Stefansson

Nat Commun 2019 10 22;10(1):4803. Epub 2019 Oct 22.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41467-019-12682-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805929PMC
October 2019

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 10 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Authors:
Alexander Teumer Yong Li Sahar Ghasemi Bram P Prins Matthias Wuttke Tobias Hermle Ayush Giri Karsten B Sieber Chengxiang Qiu Holger Kirsten Adrienne Tin Audrey Y Chu Nisha Bansal Mary F Feitosa Lihua Wang Jin-Fang Chai Massimiliano Cocca Christian Fuchsberger Mathias Gorski Anselm Hoppmann Katrin Horn Man Li Jonathan Marten Damia Noce Teresa Nutile Sanaz Sedaghat Gardar Sveinbjornsson Bamidele O Tayo Peter J van der Most Yizhe Xu Zhi Yu Lea Gerstner Johan Ärnlöv Stephan J L Bakker Daniela Baptista Mary L Biggs Eric Boerwinkle Hermann Brenner Ralph Burkhardt Robert J Carroll Miao-Li Chee Miao-Ling Chee Mengmeng Chen Ching-Yu Cheng James P Cook Josef Coresh Tanguy Corre John Danesh Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Katalin Dittrich Jasmin Divers Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Janine F Felix Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Ron T Gansevoort Vilmantas Giedraitis Martin Gögele Franziska Grundner-Culemann Daniel F Gudbjartsson Vilmundur Gudnason Pavel Hamet Tamara B Harris Andrew A Hicks Hilma Holm Valencia Hui Xian Foo Shih-Jen Hwang M Arfan Ikram Erik Ingelsson Vincent W V Jaddoe Johanna Jakobsdottir Navya Shilpa Josyula Bettina Jung Mika Kähönen Chiea-Chuen Khor Wieland Kiess Wolfgang Koenig Antje Körner Peter Kovacs Holly Kramer Bernhard K Krämer Florian Kronenberg Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jianjun Liu Markus Loeffler Leo-Pekka Lyytikäinen Anubha Mahajan Joseph C Maranville Deborah Mascalzoni Barbara McMullen Christa Meisinger Thomas Meitinger Kozeta Miliku Dennis O Mook-Kanamori Martina Müller-Nurasyid Josyf C Mychaleckyj Matthias Nauck Kjell Nikus Boting Ning Raymond Noordam Jeffrey O' Connell Isleifur Olafsson Nicholette D Palmer Annette Peters Anna I Podgornaia Belen Ponte Tanja Poulain Peter P Pramstaller Ton J Rabelink Laura M Raffield Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Fernando Rivadeneira Heiko Runz Kathleen A Ryan Charumathi Sabanayagam Kai-Uwe Saum Ben Schöttker Christian M Shaffer Yuan Shi Albert V Smith Konstantin Strauch Michael Stumvoll Benjamin B Sun Silke Szymczak E-Shyong Tai Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Unnur Thorsteinsdottir Anke Tönjes Johanne Tremblay André G Uitterlinden Pim van der Harst Niek Verweij Suzanne Vogelezang Uwe Völker Melanie Waldenberger Chaolong Wang Otis D Wilson Charlene Wong Tien-Yin Wong Qiong Yang Masayuki Yasuda Shreeram Akilesh Murielle Bochud Carsten A Böger Olivier Devuyst Todd L Edwards Kevin Ho Andrew P Morris Afshin Parsa Sarah A Pendergrass Bruce M Psaty Jerome I Rotter Kari Stefansson James G Wilson Katalin Susztak Harold Snieder Iris M Heid Markus Scholz Adam S Butterworth Adriana M Hung Cristian Pattaro Anna Köttgen

Nat Commun 2019 09 11;10(1):4130. Epub 2019 Sep 11.

Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739370PMC
September 2019

Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes.

Authors:
Molly Went Ben Kinnersley Amit Sud David C Johnson Niels Weinhold Asta Försti Mark van Duin Giulia Orlando Jonathan S Mitchell Rowan Kuiper Brian A Walker Walter M Gregory Per Hoffmann Graham H Jackson Markus M Nöthen Miguel Inacio da Silva Filho Hauke Thomsen Annemiek Broyl Faith E Davies Unnur Thorsteinsdottir Markus Hansson Martin Kaiser Pieter Sonneveld Hartmut Goldschmidt Kari Stefansson Kari Hemminki Björn Nilsson Gareth J Morgan Richard S Houlston

Hum Genomics 2019 08 20;13(1):37. Epub 2019 Aug 20.

Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700979PMC
August 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2019 Jul;51(7):1191-1192

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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July 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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July 2019

Roadmap for a precision-medicine initiative in the Nordic region.

Authors:
Pål Rasmus Njølstad Ole Andreas Andreassen Søren Brunak Anders D Børglum Joakim Dillner Tõnu Esko Paul W Franks Nelson Freimer Leif Groop Hakon Heimer David M Hougaard Eivind Hovig Kristian Hveem Anu Jalanko Jaakko Kaprio Gun Peggy Knudsen Mads Melbye Andres Metspalu Preben Bo Mortensen Juni Palmgren Aarno Palotie Wenche Reed Hreinn Stefánsson Nathan O Stitziel Patrick F Sullivan Unnur Thorsteinsdóttir Marc Vaudel Eero Vuorio Thomas Werge Camilla Stoltenberg Kári Stefánsson

Nat Genet 2019 06;51(6):924-930

deCODE Genetics, Reykjavik, Iceland.

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June 2019

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.

Authors:
Unnur Styrkarsdottir Olafur A Stefansson Kristbjorg Gunnarsdottir Gudmar Thorleifsson Sigrun H Lund Lilja Stefansdottir Kristinn Juliusson Arna B Agustsdottir Florian Zink Gisli H Halldorsson Erna V Ivarsdottir Stefania Benonisdottir Hakon Jonsson Arnaldur Gylfason Kristjan Norland Katerina Trajanoska Cindy G Boer Lorraine Southam Jason C S Leung Nelson L S Tang Timothy C Y Kwok Jenny S W Lee Suzanne C Ho Inger Byrjalsen Jacqueline R Center Seung Hun Lee Jung-Min Koh L Stefan Lohmander Lan T Ho-Pham Tuan V Nguyen John A Eisman Jean Woo Ping-C Leung John Loughlin Eleftheria Zeggini Claus Christiansen Fernando Rivadeneira Joyce van Meurs Andre G Uitterlinden Brynjolfur Mogensen Helgi Jonsson Thorvaldur Ingvarsson Gunnar Sigurdsson Rafn Benediktsson Patrick Sulem Ingileif Jonsdottir Gisli Masson Hilma Holm Gudmundur L Norddahl Unnur Thorsteinsdottir Daniel F Gudbjartsson Kari Stefansson

Nat Commun 2019 05 3;10(1):2054. Epub 2019 May 3.

deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.

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http://www.nature.com/articles/s41467-019-09860-0
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499783PMC
May 2019

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.

Authors:
Unnur Styrkarsdottir Olafur A Stefansson Kristbjorg Gunnarsdottir Gudmar Thorleifsson Sigrun H Lund Lilja Stefansdottir Kristinn Juliusson Arna B Agustsdottir Florian Zink Gisli H Halldorsson Erna V Ivarsdottir Stefania Benonisdottir Hakon Jonsson Arnaldur Gylfason Kristjan Norland Katerina Trajanoska Cindy G Boer Lorraine Southam Jason C S Leung Nelson L S Tang Timothy C Y Kwok Jenny S W Lee Suzanne C Ho Inger Byrjalsen Jacqueline R Center Seung Hun Lee Jung-Min Koh L Stefan Lohmander Lan T Ho-Pham Tuan V Nguyen John A Eisman Jean Woo Ping-C Leung John Loughlin Eleftheria Zeggini Claus Christiansen Fernando Rivadeneira Joyce van Meurs Andre G Uitterlinden Brynjolfur Mogensen Helgi Jonsson Thorvaldur Ingvarsson Gunnar Sigurdsson Rafn Benediktsson Patrick Sulem Ingileif Jonsdottir Gisli Masson Hilma Holm Gudmundur L Norddahl Unnur Thorsteinsdottir Daniel F Gudbjartsson Kari Stefansson

Nat Commun 2019 May 24;10(1):2358. Epub 2019 May 24.

deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534558PMC
May 2019

Sequence variants associating with urinary biomarkers.

Authors:
Stefania Benonisdottir Ragnar P Kristjansson Asmundur Oddsson Valgerdur Steinthorsdottir Evgenia Mikaelsdottir Birte Kehr Brynjar O Jensson Gudny A Arnadottir Gerald Sulem Gardar Sveinbjornsson Snaedis Kristmundsdottir Erna V Ivarsdottir Vinicius Tragante Bjarni Gunnarsson Hrafnhildur Linnet Runolfsdottir Joseph G Arthur Aimee M Deaton Gudmundur I Eyjolfsson Olafur B Davidsson Folkert W Asselbergs Astradur B Hreidarsson Thorunn Rafnar Gudmar Thorleifsson Vidar Edvardsson Gunnar Sigurdsson Anna Helgadottir Bjarni V Halldorsson Gisli Masson Hilma Holm Pall T Onundarson Olafur S Indridason Rafn Benediktsson Runolfur Palsson Daniel F Gudbjartsson Isleifur Olafsson Unnur Thorsteinsdottir Patrick Sulem Kari Stefansson

Hum Mol Genet 2019 04;28(7):1199-1211

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1093/hmg/ddy409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423415PMC
April 2019

A PRPH splice-donor variant associates with reduced sural nerve amplitude and risk of peripheral neuropathy.

Authors:
Gyda Bjornsdottir Erna V Ivarsdottir Kristbjorg Bjarnadottir Stefania Benonisdottir Sandra Sif Gylfadottir Gudny A Arnadottir Rafn Benediktsson Gisli Hreinn Halldorsson Anna Helgadottir Adalbjorg Jonasdottir Aslaug Jonasdottir Ingileif Jonsdottir Anna Margret Kristinsdottir Olafur Th Magnusson Gisli Masson Pall Melsted Thorunn Rafnar Asgeir Sigurdsson Gunnar Sigurdsson Astros Skuladottir Valgerdur Steinthorsdottir Unnur Styrkarsdottir Gudmundur Thorgeirsson Gudmar Thorleifsson Arnor Vikingsson Daniel F Gudbjartsson Hilma Holm Hreinn Stefansson Unnur Thorsteinsdottir Gudmundur L Norddahl Patrick Sulem Thorgeir E Thorgeirsson Kari Stefansson

Nat Commun 2019 04 16;10(1):1777. Epub 2019 Apr 16.

deCODE Genetics/Amgen, Inc., 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41467-019-09719-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468012PMC
April 2019

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Authors:
Anne E Justice Tugce Karaderi Heather M Highland Kristin L Young Mariaelisa Graff Yingchang Lu Valérie Turcot Paul L Auer Rebecca S Fine Xiuqing Guo Claudia Schurmann Adelheid Lempradl Eirini Marouli Anubha Mahajan Thomas W Winkler Adam E Locke Carolina Medina-Gomez Tõnu Esko Sailaja Vedantam Ayush Giri Ken Sin Lo Tamuno Alfred Poorva Mudgal Maggie C Y Ng Nancy L Heard-Costa Mary F Feitosa Alisa K Manning Sara M Willems Suthesh Sivapalaratnam Goncalo Abecasis Dewan S Alam Matthew Allison Philippe Amouyel Zorayr Arzumanyan Beverley Balkau Lisa Bastarache Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Erwin P Bottinger Donald W Bowden Ivan Brandslund Linda Broer Amber A Burt Adam S Butterworth Mark J Caulfield Giancarlo Cesana John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Francis S Collins James P Cook Amanda J Cox David S Crosslin John Danesh Paul I W de Bakker Simon de Denus Renée de Mutsert George Dedoussis Ellen W Demerath Joe G Dennis Josh C Denny Emanuele Di Angelantonio Marcus Dörr Fotios Drenos Marie-Pierre Dubé Alison M Dunning Douglas F Easton Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Myriam Fornage Caroline S Fox Paul W Franks Nele Friedrich Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Giorgia Girotto Mathias Gorski Harald Grallert Niels Grarup Megan L Grove Stefan Gustafsson Jeff Haessler Torben Hansen Andrew T Hattersley Caroline Hayward Iris M Heid Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Yi-Jen Hung Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Gail P Jarvik Yucheng Jia Torben Jørgensen Pekka Jousilahti Johanne M Justesen Bratati Kahali Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Peter Kovacs Bernhard K Krämer Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Wen-Jane Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Jian'an Luan Leo-Pekka Lyytikäinen Stuart MacGregor Reedik Mägi Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G D Masca Mark I McCarthy Karina Meidtner Evelin Mihailov Leena Moilanen Marie Moitry Dennis O Mook-Kanamori Anna Morgan Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Narisu Narisu Christopher P Nelson Matt Neville Ioanna Ntalla Jeffrey R O'Connell Katharine R Owen Oluf Pedersen Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Ailith Ewing Ozren Polasek Olli T Raitakari Asif Rasheed Chelsea K Raulerson Rainer Rauramaa Dermot F Reilly Alex P Reiner Paul M Ridker Manuel A Rivas Neil R Robertson Antonietta Robino Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo Segura-Lepe Xueling Sim Andrew J Slater Kerrin S Small Blair H Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Karin M A Swart Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Mina Torres Emmanouil Tsafantakis Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Cornelia M van Duijn Mauno Vanhala Rohit Varma Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao He Zheng Wei Zhou M Carola Zillikens Fernando Rivadeneira Ingrid B Borecki J Andrew Pospisilik Panos Deloukas Timothy M Frayling Guillaume Lettre Karen L Mohlke Jerome I Rotter Zoltán Kutalik Joel N Hirschhorn L Adrienne Cupples Ruth J F Loos Kari E North Cecilia M Lindgren

Nat Genet 2019 03 18;51(3):452-469. Epub 2019 Feb 18.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560635PMC
March 2019

Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density.

Authors:
Erna V Ivarsdottir Stefania Benonisdottir Gudmar Thorleifsson Patrick Sulem Asmundur Oddsson Unnur Styrkarsdottir Snaedis Kristmundsdottir Gudny A Arnadottir Gudmundur Thorgeirsson Ingileif Jonsdottir Gunnar M Zoega Unnur Thorsteinsdottir Daniel F Gudbjartsson Fridbert Jonasson Hilma Holm Kari Stefansson

Nat Commun 2019 03 20;10(1):1284. Epub 2019 Mar 20.

deCODE genetics/Amgen, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41467-019-09304-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427039PMC
March 2019

A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.

Authors:
Ragnar P Kristjansson Stefania Benonisdottir Olafur B Davidsson Asmundur Oddsson Vinicius Tragante Jon K Sigurdsson Lilja Stefansdottir Stefan Jonsson Brynjar O Jensson Joseph G Arthur Gudny A Arnadottir Gerald Sulem Bjarni V Halldorsson Bjarni Gunnarsson Gisli H Halldorsson Olafur A Stefansson Gudjon R Oskarsson Aimee M Deaton Isleifur Olafsson Gudmundur I Eyjolfsson Olof Sigurdardottir Pall T Onundarson David Gislason Thorarinn Gislason Bjorn R Ludviksson Dora Ludviksdottir Thorunn A Olafsdottir Thorunn Rafnar Gisli Masson Florian Zink Gyda Bjornsdottir Olafur Th Magnusson Unnur S Bjornsdottir Gudmar Thorleifsson Gudmundur L Norddahl Daniel F Gudbjartsson Unnur Thorsteinsdottir Ingileif Jonsdottir Patrick Sulem Kari Stefansson

Nat Genet 2019 02 14;51(2):267-276. Epub 2019 Jan 14.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41588-018-0314-6DOI Listing
February 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 02;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Authors:
Molly Went Amit Sud Asta Försti Britt-Marie Halvarsson Niels Weinhold Scott Kimber Mark van Duin Gudmar Thorleifsson Amy Holroyd David C Johnson Ni Li Giulia Orlando Philip J Law Mina Ali Bowang Chen Jonathan S Mitchell Daniel F Gudbjartsson Rowan Kuiper Owen W Stephens Uta Bertsch Peter Broderick Chiara Campo Obul R Bandapalli Hermann Einsele Walter A Gregory Urban Gullberg Jens Hillengass Per Hoffmann Graham H Jackson Karl-Heinz Jöckel Ellinor Johnsson Sigurður Y Kristinsson Ulf-Henrik Mellqvist Hareth Nahi Douglas Easton Paul Pharoah Alison Dunning Julian Peto Federico Canzian Anthony Swerdlow Rosalind A Eeles Zsofia Kote-Jarai Kenneth Muir Nora Pashayan Jolanta Nickel Markus M Nöthen Thorunn Rafnar Fiona M Ross Miguel Inacio da Silva Filho Hauke Thomsen Ingemar Turesson Annette Vangsted Niels Frost Andersen Anders Waage Brian A Walker Anna-Karin Wihlborg Annemiek Broyl Faith E Davies Unnur Thorsteinsdottir Christian Langer Markus Hansson Hartmut Goldschmidt Martin Kaiser Pieter Sonneveld Kari Stefansson Gareth J Morgan Kari Hemminki Björn Nilsson Richard S Houlston

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Characterizing mutagenic effects of recombination through a sequence-level genetic map.

Authors:
Bjarni V Halldorsson Gunnar Palsson Olafur A Stefansson Hakon Jonsson Marteinn T Hardarson Hannes P Eggertsson Bjarni Gunnarsson Asmundur Oddsson Gisli H Halldorsson Florian Zink Sigurjon A Gudjonsson Michael L Frigge Gudmar Thorleifsson Asgeir Sigurdsson Simon N Stacey Patrick Sulem Gisli Masson Agnar Helgason Daniel F Gudbjartsson Unnur Thorsteinsdottir Kari Stefansson

Science 2019 Jan;363(6425)

deCODE genetics, Amgen, Sturlugata 8, Reykjavik, Iceland.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aau1043
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January 2019

Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis.

Authors:
Unnur Styrkarsdottir Sigrun H Lund Gudmar Thorleifsson Florian Zink Olafur A Stefansson Jon K Sigurdsson Kristinn Juliusson Kristbjörg Bjarnadottir Sara Sigurbjornsdottir Stefan Jonsson Kristjan Norland Lilja Stefansdottir Asgeir Sigurdsson Gardar Sveinbjornsson Asmundur Oddsson Gyda Bjornsdottir Reynir L Gudmundsson Gisli H Halldorsson Thorunn Rafnar Ingileif Jonsdottir Eirikur Steingrimsson Gudmundur L Norddahl Gisli Masson Patrick Sulem Helgi Jonsson Thorvaldur Ingvarsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2018 12 29;50(12):1681-1687. Epub 2018 Oct 29.

deCODE genetics/Amgen, Inc., Reykjavik, Iceland.

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http://www.nature.com/articles/s41588-018-0247-0
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December 2018

Multiple transmissions of de novo mutations in families.

Authors:
Hákon Jónsson Patrick Sulem Gudny A Arnadottir Gunnar Pálsson Hannes P Eggertsson Snaedis Kristmundsdottir Florian Zink Birte Kehr Kristjan E Hjorleifsson Brynjar Ö Jensson Ingileif Jonsdottir Sigurdur Einar Marelsson Sigurjon Axel Gudjonsson Arnaldur Gylfason Adalbjorg Jonasdottir Aslaug Jonasdottir Simon N Stacey Olafur Th Magnusson Unnur Thorsteinsdottir Gisli Masson Augustine Kong Bjarni V Halldorsson Agnar Helgason Daniel F Gudbjartsson Kari Stefansson

Nat Genet 2018 12 5;50(12):1674-1680. Epub 2018 Nov 5.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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http://www.nature.com/articles/s41588-018-0259-9
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December 2018

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.

Authors:
Felix Day Tugce Karaderi Michelle R Jones Cindy Meun Chunyan He Alex Drong Peter Kraft Nan Lin Hongyan Huang Linda Broer Reedik Magi Richa Saxena Triin Laisk Margrit Urbanek M Geoffrey Hayes Gudmar Thorleifsson Juan Fernandez-Tajes Anubha Mahajan Benjamin H Mullin Bronwyn G A Stuckey Timothy D Spector Scott G Wilson Mark O Goodarzi Lea Davis Barbara Obermayer-Pietsch André G Uitterlinden Verneri Anttila Benjamin M Neale Marjo-Riitta Jarvelin Bart Fauser Irina Kowalska Jenny A Visser Marianne Andersen Ken Ong Elisabet Stener-Victorin David Ehrmann Richard S Legro Andres Salumets Mark I McCarthy Laure Morin-Papunen Unnur Thorsteinsdottir Kari Stefansson Unnur Styrkarsdottir John R B Perry Andrea Dunaif Joop Laven Steve Franks Cecilia M Lindgren Corrine K Welt

PLoS Genet 2018 12 19;14(12):e1007813. Epub 2018 Dec 19.

Division of Endocrinology, Metabolism and Diabetes, University of Utah, Salt Lake City, Utah, United States of America.

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http://dx.plos.org/10.1371/journal.pgen.1007813
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300389PMC
December 2018

Author Correction: The rate of meiotic gene conversion varies by sex and age.

Authors:
Bjarni V Halldorsson Marteinn T Hardarson Birte Kehr Unnur Styrkarsdottir Arnaldur Gylfason Gudmar Thorleifsson Florian Zink Adalbjorg Jonasdottir Aslaug Jonasdottir Patrick Sulem Gisli Masson Unnur Thorsteinsdottir Agnar Helgason Augustine Kong Daniel F Gudbjartsson Kari Stefansson

Nat Genet 2018 11;50(11):1616

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://www.nature.com/articles/s41588-018-0228-3
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November 2018

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

Authors:
Anubha Mahajan Daniel Taliun Matthias Thurner Neil R Robertson Jason M Torres N William Rayner Anthony J Payne Valgerdur Steinthorsdottir Robert A Scott Niels Grarup James P Cook Ellen M Schmidt Matthias Wuttke Chloé Sarnowski Reedik Mägi Jana Nano Christian Gieger Stella Trompet Cécile Lecoeur Michael H Preuss Bram Peter Prins Xiuqing Guo Lawrence F Bielak Jennifer E Below Donald W Bowden John Campbell Chambers Young Jin Kim Maggie C Y Ng Lauren E Petty Xueling Sim Weihua Zhang Amanda J Bennett Jette Bork-Jensen Chad M Brummett Mickaël Canouil Kai-Uwe Ec Kardt Krista Fischer Sharon L R Kardia Florian Kronenberg Kristi Läll Ching-Ti Liu Adam E Locke Jian'an Luan Ioanna Ntalla Vibe Nylander Sebastian Schönherr Claudia Schurmann Loïc Yengo Erwin P Bottinger Ivan Brandslund Cramer Christensen George Dedoussis Jose C Florez Ian Ford Oscar H Franco Timothy M Frayling Vilmantas Giedraitis Sophie Hackinger Andrew T Hattersley Christian Herder M Arfan Ikram Martin Ingelsson Marit E Jørgensen Torben Jørgensen Jennifer Kriebel Johanna Kuusisto Symen Ligthart Cecilia M Lindgren Allan Linneberg Valeriya Lyssenko Vasiliki Mamakou Thomas Meitinger Karen L Mohlke Andrew D Morris Girish Nadkarni James S Pankow Annette Peters Naveed Sattar Alena Stančáková Konstantin Strauch Kent D Taylor Barbara Thorand Gudmar Thorleifsson Unnur Thorsteinsdottir Jaakko Tuomilehto Daniel R Witte Josée Dupuis Patricia A Peyser Eleftheria Zeggini Ruth J F Loos Philippe Froguel Erik Ingelsson Lars Lind Leif Groop Markku Laakso Francis S Collins J Wouter Jukema Colin N A Palmer Harald Grallert Andres Metspalu Abbas Dehghan Anna Köttgen Goncalo R Abecasis James B Meigs Jerome I Rotter Jonathan Marchini Oluf Pedersen Torben Hansen Claudia Langenberg Nicholas J Wareham Kari Stefansson Anna L Gloyn Andrew P Morris Michael Boehnke Mark I McCarthy

Nat Genet 2018 11 8;50(11):1505-1513. Epub 2018 Oct 8.

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287706PMC
November 2018

Insights into imprinting from parent-of-origin phased methylomes and transcriptomes.

Authors:
Florian Zink Droplaug N Magnusdottir Olafur T Magnusson Nicolas J Walker Tiffany J Morris Asgeir Sigurdsson Gisli H Halldorsson Sigurjon A Gudjonsson Pall Melsted Helga Ingimundardottir Snædis Kristmundsdottir Kristjan F Alexandersson Anna Helgadottir Julius Gudmundsson Thorunn Rafnar Ingileif Jonsdottir Hilma Holm Gudmundur Ingi Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Gisli Masson Daniel F Gudbjartsson Unnur Thorsteinsdottir Bjarni V Halldorsson Simon N Stacey Kari Stefansson

Nat Genet 2018 11 22;50(11):1542-1552. Epub 2018 Oct 22.

deCODE genetics/AMGEN, Reykjavik, Iceland.

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http://www.nature.com/articles/s41588-018-0232-7
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November 2018

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.

Authors:
Julius Gudmundsson Jon K Sigurdsson Lilja Stefansdottir Bjarni A Agnarsson Helgi J Isaksson Olafur A Stefansson Sigurjon A Gudjonsson Daniel F Gudbjartsson Gisli Masson Michael L Frigge Simon N Stacey Patrick Sulem Gisli H Halldorsson Vinicius Tragante Hilma Holm Gudmundur I Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Thorvaldur Jonsson Eirikur Jonsson Rosa B Barkardottir Rafn Hilmarsson Folkert W Asselbergs Gudmundur Geirsson Unnur Thorsteinsdottir Thorunn Rafnar Gudmar Thorleifsson Kari Stefansson

Nat Commun 2018 11 8;9(1):4568. Epub 2018 Nov 8.

deCODE genetics/AMGEN, 101, Reykjavik, Iceland.

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http://www.nature.com/articles/s41467-018-06920-9
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224563PMC
November 2018

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

Authors:
Egil Ferkingstad Asmundur Oddsson Solveig Gretarsdottir Stefania Benonisdottir Gudmar Thorleifsson Aimee M Deaton Stefan Jonsson Olafur A Stefansson Gudmundur L Norddahl Florian Zink Gudny A Arnadottir Bjarni Gunnarsson Gisli H Halldorsson Anna Helgadottir Brynjar O Jensson Ragnar P Kristjansson Gardar Sveinbjornsson David A Sverrisson Gisli Masson Isleifur Olafsson Gudmundur I Eyjolfsson Olof Sigurdardottir Hilma Holm Ingileif Jonsdottir Sigurdur Olafsson Thora Steingrimsdottir Thorunn Rafnar Einar S Bjornsson Unnur Thorsteinsdottir Daniel F Gudbjartsson Patrick Sulem Kari Stefansson

Nat Commun 2018 11 30;9(1):5101. Epub 2018 Nov 30.

deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland.

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http://dx.doi.org/10.1038/s41467-018-07460-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269469PMC
November 2018

A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease.

Authors:
Gudny A Arnadottir Gudmundur L Norddahl Steinunn Gudmundsdottir Arna B Agustsdottir Snaevar Sigurdsson Brynjar O Jensson Kristbjorg Bjarnadottir Fannar Theodors Stefania Benonisdottir Erna V Ivarsdottir Asmundur Oddsson Ragnar P Kristjansson Gerald Sulem Kristjan F Alexandersson Thorhildur Juliusdottir Kjartan R Gudmundsson Jona Saemundsdottir Adalbjorg Jonasdottir Aslaug Jonasdottir Asgeir Sigurdsson Paolo Manzanillo Sigurjon A Gudjonsson Gudmundur A Thorisson Olafur Th Magnusson Gisli Masson Kjartan B Orvar Hilma Holm Sigurdur Bjornsson Reynir Arngrimsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Ingileif Jonsdottir Asgeir Haraldsson Patrick Sulem Kari Stefansson

Nat Commun 2018 10 25;9(1):4447. Epub 2018 Oct 25.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://www.nature.com/articles/s41467-018-06964-x
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202333PMC
October 2018

A rare missense mutation in MYH6 associates with non-syndromic coarctation of the aorta.

Authors:
Thorsteinn Bjornsson Rosa B Thorolfsdottir Gardar Sveinbjornsson Patrick Sulem Gudmundur L Norddahl Anna Helgadottir Solveig Gretarsdottir Audur Magnusdottir Ragnar Danielsen Emil L Sigurdsson Berglind Adalsteinsdottir Sverrir I Gunnarsson Ingileif Jonsdottir David O Arnar Hrodmar Helgason Tomas Gudbjartsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Hilma Holm Kari Stefansson

Eur Heart J 2018 09;39(34):3243-3249

deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland.

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http://dx.doi.org/10.1093/eurheartj/ehy142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127890PMC
September 2018

Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin.

Authors:
Thorunn Rafnar Gudbjorg R Sigurjonsdottir Simon N Stacey Gisli Halldorsson Patrick Sulem Luba M Pardo Hannes Helgason Stefan T Sigurdsson Thorkell Gudjonsson Laufey Tryggvadottir Gudridur H Olafsdottir Jon G Jonasson Kristin Alexiusdottir Asgeir Sigurdsson Julius Gudmundsson Jona Saemundsdottir Jon K Sigurdsson Hrefna Johannsdottir Andre Uitterlinden Sita H Vermeulen Tessel E Galesloot Dawn C Allain Martin Lacko Bardur Sigurgeirsson Kristin Thorisdottir Oskar T Johannsson Fridbjorn Sigurdsson Gunnar B Ragnarsson Helgi Isaksson Hronn Hardardottir Tomas Gudbjartsson Daniel F Gudbjartsson Gisli Masson Lambertus A M L Kiemeney Amanda Ewart Toland Tamar Nijsten Wilbert H M Peters Jon H Olafsson Steinn Jonsson Unnur Thorsteinsdottir Gudmar Thorleifsson Kari Stefansson

J Natl Cancer Inst 2018 09;110(9):967-974

deCODE Genetics/Amgen, Reykjavik, Iceland.

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http://dx.doi.org/10.1093/jnci/djy002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136924PMC
September 2018

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

Authors:
Jonas B Nielsen Rosa B Thorolfsdottir Lars G Fritsche Wei Zhou Morten W Skov Sarah E Graham Todd J Herron Shane McCarthy Ellen M Schmidt Gardar Sveinbjornsson Ida Surakka Michael R Mathis Masatoshi Yamazaki Ryan D Crawford Maiken E Gabrielsen Anne Heidi Skogholt Oddgeir L Holmen Maoxuan Lin Brooke N Wolford Rounak Dey Håvard Dalen Patrick Sulem Jonathan H Chung Joshua D Backman David O Arnar Unnur Thorsteinsdottir Aris Baras Colm O'Dushlaine Anders G Holst Xiaoquan Wen Whitney Hornsby Frederick E Dewey Michael Boehnke Sachin Kheterpal Bhramar Mukherjee Seunggeun Lee Hyun M Kang Hilma Holm Jacob Kitzman Jordan A Shavit José Jalife Chad M Brummett Tanya M Teslovich David J Carey Daniel F Gudbjartsson Kari Stefansson Gonçalo R Abecasis Kristian Hveem Cristen J Willer

Nat Genet 2018 09 30;50(9):1234-1239. Epub 2018 Jul 30.

Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41588-018-0171-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530775PMC
September 2018

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

Authors:
Kerrin S Small Marijana Todorčević Mete Civelek Julia S El-Sayed Moustafa Xiao Wang Michelle M Simon Juan Fernandez-Tajes Anubha Mahajan Momoko Horikoshi Alison Hugill Craig A Glastonbury Lydia Quaye Matt J Neville Siddharth Sethi Marianne Yon Calvin Pan Nam Che Ana Vinuela Pei-Chien Tsai Abhishek Nag Alfonso Buil Gudmar Thorleifsson Avanthi Raghavan Qiurong Ding Andrew P Morris Jordana T Bell Unnur Thorsteinsdottir Kari Stefansson Markku Laakso Ingrid Dahlman Peter Arner Anna L Gloyn Kiran Musunuru Aldons J Lusis Roger D Cox Fredrik Karpe Mark I McCarthy

Nat Genet 2018 09;50(9):1342

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.

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September 2018

Relatedness disequilibrium regression estimates heritability without environmental bias.

Authors:
Alexander I Young Michael L Frigge Daniel F Gudbjartsson Gudmar Thorleifsson Gyda Bjornsdottir Patrick Sulem Gisli Masson Unnur Thorsteinsdottir Kari Stefansson Augustine Kong

Nat Genet 2018 09 13;50(9):1304-1310. Epub 2018 Aug 13.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41588-018-0178-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130754PMC
September 2018

Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.

Authors:
Thorunn Rafnar Bjarni Gunnarsson Olafur A Stefansson Patrick Sulem Andres Ingason Michael L Frigge Lilja Stefansdottir Jon K Sigurdsson Vinicius Tragante Valgerdur Steinthorsdottir Unnur Styrkarsdottir Simon N Stacey Julius Gudmundsson Gudny A Arnadottir Asmundur Oddsson Florian Zink Gisli Halldorsson Gardar Sveinbjornsson Ragnar P Kristjansson Olafur B Davidsson Anna Salvarsdottir Asgeir Thoroddsen Elisabet A Helgadottir Katrin Kristjansdottir Orri Ingthorsson Valur Gudmundsson Reynir T Geirsson Ragnheidur Arnadottir Daniel F Gudbjartsson Gisli Masson Folkert W Asselbergs Jon G Jonasson Karl Olafsson Unnur Thorsteinsdottir Bjarni V Halldorsson Gudmar Thorleifsson Kari Stefansson

Nat Commun 2018 09 7;9(1):3636. Epub 2018 Sep 7.

deCODE Genetics/Amgen, Sturlugata 8, 101, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41467-018-05428-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128903PMC
September 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Authors:
Molly Went Amit Sud Asta Försti Britt-Marie Halvarsson Niels Weinhold Scott Kimber Mark van Duin Gudmar Thorleifsson Amy Holroyd David C Johnson Ni Li Giulia Orlando Philip J Law Mina Ali Bowang Chen Jonathan S Mitchell Daniel F Gudbjartsson Rowan Kuiper Owen W Stephens Uta Bertsch Peter Broderick Chiara Campo Obul R Bandapalli Hermann Einsele Walter A Gregory Urban Gullberg Jens Hillengass Per Hoffmann Graham H Jackson Karl-Heinz Jöckel Ellinor Johnsson Sigurður Y Kristinsson Ulf-Henrik Mellqvist Hareth Nahi Douglas Easton Paul Pharoah Alison Dunning Julian Peto Federico Canzian Anthony Swerdlow Rosalind A Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan Jolanta Nickel Markus M Nöthen Thorunn Rafnar Fiona M Ross Miguel Inacio da Silva Filho Hauke Thomsen Ingemar Turesson Annette Vangsted Niels Frost Andersen Anders Waage Brian A Walker Anna-Karin Wihlborg Annemiek Broyl Faith E Davies Unnur Thorsteinsdottir Christian Langer Markus Hansson Hartmut Goldschmidt Martin Kaiser Pieter Sonneveld Kari Stefansson Gareth J Morgan Kari Hemminki Björn Nilsson Richard S Houlston

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

Corrigendum to "Quantitative UPLC-MS/MS assay of urinary 2,8-dihydroxyadenine for diagnosis and management of adenine phosphoribosyltransferase deficiency" [J. Chromatogr. B 1036-1037 (2016) 170-177].

Authors:
Margret Thorsteinsdottir Unnur A Thorsteinsdottir Finnur F Eiriksson Hrafnhildur L Runolfsdottir Inger M Sch Agustsdottir Steinunn Oddsdottir Baldur B Sigurdsson Hordur K Hardarson Nilesh R Kamble Snorri Th Sigurdsson Vidar O Edvardsson Runolfur Palsson

J Chromatogr B Analyt Technol Biomed Life Sci 2018 08 1;1092:530. Epub 2018 Jun 1.

University of Iceland, Reykjavik, Iceland; Division of Nephrology, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.jchromb.2018.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390279PMC
August 2018

Variants in NKX2-5 and FLNC Cause Dilated Cardiomyopathy and Sudden Cardiac Death.

Authors:
Gardar Sveinbjornsson Eva F Olafsdottir Rosa B Thorolfsdottir Olafur B Davidsson Anna Helgadottir Adalbjorg Jonasdottir Aslaug Jonasdottir Eythor Bjornsson Brynjar O Jensson Gudny A Arnadottir Hallfridur Kristinsdottir Sigurdur S Stephensen Gylfi Oskarsson Tomas Gudbjartsson Emil L Sigurdsson Karl Andersen Ragnar Danielsen David O Arnar Ingileif Jonsdottir Unnur Thorsteinsdottir Patrick Sulem Gudmundur Thorgeirsson Daniel F Gudbjartsson Hilma Holm Kari Stefansson

Circ Genom Precis Med 2018 08;11(8):e002151

Adalbjorg Jonasdottir, Aslaug Jonasdottir, E.B., B.O.J., G.A.A., D.O.A., I.J., U.T., P.S., G.T., D.F.G., H.H., K.S.).

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August 2018

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.

Authors:
Bram P Prins Timothy J Mead Jennifer A Brody Gardar Sveinbjornsson Ioanna Ntalla Nathan A Bihlmeyer Marten van den Berg Jette Bork-Jensen Stefania Cappellani Stefan Van Duijvenboden Nikolai T Klena George C Gabriel Xiaoqin Liu Cagri Gulec Niels Grarup Jeffrey Haessler Leanne M Hall Annamaria Iorio Aaron Isaacs Ruifang Li-Gao Honghuang Lin Ching-Ti Liu Leo-Pekka Lyytikäinen Jonathan Marten Hao Mei Martina Müller-Nurasyid Michele Orini Sandosh Padmanabhan Farid Radmanesh Julia Ramirez Antonietta Robino Molly Schwartz Jessica van Setten Albert V Smith Niek Verweij Helen R Warren Stefan Weiss Alvaro Alonso David O Arnar Michiel L Bots Rudolf A de Boer Anna F Dominiczak Mark Eijgelsheim Patrick T Ellinor Xiuqing Guo Stephan B Felix Tamara B Harris Caroline Hayward Susan R Heckbert Paul L Huang J W Jukema Mika Kähönen Jan A Kors Pier D Lambiase Lenore J Launer Man Li Allan Linneberg Christopher P Nelson Oluf Pedersen Marco Perez Annette Peters Ozren Polasek Bruce M Psaty Olli T Raitakari Kenneth M Rice Jerome I Rotter Moritz F Sinner Elsayed Z Soliman Tim D Spector Konstantin Strauch Unnur Thorsteinsdottir Andrew Tinker Stella Trompet André Uitterlinden Ilonca Vaartjes Peter van der Meer Uwe Völker Henry Völzke Melanie Waldenberger James G Wilson Zhijun Xie Folkert W Asselbergs Marcus Dörr Cornelia M van Duijn Paolo Gasparini Daniel F Gudbjartsson Vilmundur Gudnason Torben Hansen Stefan Kääb Jørgen K Kanters Charles Kooperberg Terho Lehtimäki Henry J Lin Steven A Lubitz Dennis O Mook-Kanamori Francesco J Conti Christopher H Newton-Cheh Jonathan Rosand Igor Rudan Nilesh J Samani Gianfranco Sinagra Blair H Smith Hilma Holm Bruno H Stricker Sheila Ulivi Nona Sotoodehnia Suneel S Apte Pim van der Harst Kari Stefansson Patricia B Munroe Dan E Arking Cecilia W Lo Yalda Jamshidi

Genome Biol 2018 07 17;19(1):87. Epub 2018 Jul 17.

Genetics Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London, SW17 0RE, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048820PMC
July 2018

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

Authors:
Jessica van Setten Jennifer A Brody Yalda Jamshidi Brenton R Swenson Anne M Butler Harry Campbell Fabiola M Del Greco Daniel S Evans Quince Gibson Daniel F Gudbjartsson Kathleen F Kerr Bouwe P Krijthe Leo-Pekka Lyytikäinen Christian Müller Martina Müller-Nurasyid Ilja M Nolte Sandosh Padmanabhan Marylyn D Ritchie Antonietta Robino Albert V Smith Maristella Steri Toshiko Tanaka Alexander Teumer Stella Trompet Sheila Ulivi Niek Verweij Xiaoyan Yin David O Arnar Folkert W Asselbergs Joel S Bader John Barnard Josh Bis Stefan Blankenberg Eric Boerwinkle Yuki Bradford Brendan M Buckley Mina K Chung Dana Crawford Marcel den Hoed Josh C Denny Anna F Dominiczak Georg B Ehret Mark Eijgelsheim Patrick T Ellinor Stephan B Felix Oscar H Franco Lude Franke Tamara B Harris Hilma Holm Gandin Ilaria Annamaria Iorio Mika Kähönen Ivana Kolcic Jan A Kors Edward G Lakatta Lenore J Launer Honghuang Lin Henry J Lin Ruth J F Loos Steven A Lubitz Peter W Macfarlane Jared W Magnani Irene Mateo Leach Thomas Meitinger Braxton D Mitchell Thomas Munzel George J Papanicolaou Annette Peters Arne Pfeufer Peter P Pramstaller Olli T Raitakari Jerome I Rotter Igor Rudan Nilesh J Samani David Schlessinger Claudia T Silva Aldana Moritz F Sinner Jonathan D Smith Harold Snieder Elsayed Z Soliman Timothy D Spector David J Stott Konstantin Strauch Kirill V Tarasov Unnur Thorsteinsdottir Andre G Uitterlinden David R Van Wagoner Uwe Völker Henry Völzke Melanie Waldenberger Harm Jan Westra Philipp S Wild Tanja Zeller Alvaro Alonso Christy L Avery Stefania Bandinelli Emelia J Benjamin Francesco Cucca Marcus Dörr Luigi Ferrucci Paolo Gasparini Vilmundur Gudnason Caroline Hayward Susan R Heckbert Andrew A Hicks J Wouter Jukema Stefan Kääb Terho Lehtimäki Yongmei Liu Patricia B Munroe Afshin Parsa Ozren Polasek Bruce M Psaty Dan M Roden Renate B Schnabel Gianfranco Sinagra Kari Stefansson Bruno H Stricker Pim van der Harst Cornelia M van Duijn James F Wilson Sina A Gharib Paul I W de Bakker Aaron Isaacs Dan E Arking Nona Sotoodehnia

Nat Commun 2018 07 25;9(1):2904. Epub 2018 Jul 25.

Departments of Medicine and Epidemiology, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060178PMC
July 2018

Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease.

Authors:
Anna Helgadottir Patrick Sulem Gudmundur Thorgeirsson Solveig Gretarsdottir Gudmar Thorleifsson Brynjar Ö Jensson Gudny A Arnadottir Isleifur Olafsson Gudmundur I Eyjolfsson Olof Sigurdardottir Unnur Thorsteinsdottir Daniel F Gudbjartsson Hilma Holm Kari Stefansson

Eur Heart J 2018 06;39(23):2172-2178

deCODE Genetics/Amgen, Inc., Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1093/eurheartj/ehy169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001888PMC
June 2018

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Authors:
Viktoria Gusarova Colm O'Dushlaine Tanya M Teslovich Peter N Benotti Tooraj Mirshahi Omri Gottesman Cristopher V Van Hout Michael F Murray Anubha Mahajan Jonas B Nielsen Lars Fritsche Anders Berg Wulff Daniel F Gudbjartsson Marketa Sjögren Connor A Emdin Robert A Scott Wen-Jane Lee Aeron Small Lydia C Kwee Om Prakash Dwivedi Rashmi B Prasad Shannon Bruse Alexander E Lopez John Penn Anthony Marcketta Joseph B Leader Christopher D Still H Lester Kirchner Uyenlinh L Mirshahi Amr H Wardeh Cassandra M Hartle Lukas Habegger Samantha N Fetterolf Teresa Tusie-Luna Andrew P Morris Hilma Holm Valgerdur Steinthorsdottir Patrick Sulem Unnur Thorsteinsdottir Jerome I Rotter Lee-Ming Chuang Scott Damrauer David Birtwell Chad M Brummett Amit V Khera Pradeep Natarajan Marju Orho-Melander Jason Flannick Luca A Lotta Cristen J Willer Oddgeir L Holmen Marylyn D Ritchie David H Ledbetter Andrew J Murphy Ingrid B Borecki Jeffrey G Reid John D Overton Ola Hansson Leif Groop Svati H Shah William E Kraus Daniel J Rader Yii-Der I Chen Kristian Hveem Nicholas J Wareham Sekar Kathiresan Olle Melander Kari Stefansson Børge G Nordestgaard Anne Tybjærg-Hansen Goncalo R Abecasis David Altshuler Jose C Florez Michael Boehnke Mark I McCarthy George D Yancopoulos David J Carey Alan R Shuldiner Aris Baras Frederick E Dewey Jesper Gromada

Nat Commun 2018 06 13;9(1):2252. Epub 2018 Jun 13.

Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997992PMC
June 2018

Coding variants in and increase risk of atrial fibrillation.

Authors:
Rosa B Thorolfsdottir Gardar Sveinbjornsson Patrick Sulem Jonas B Nielsen Stefan Jonsson Gisli H Halldorsson Pall Melsted Erna V Ivarsdottir Olafur B Davidsson Ragnar P Kristjansson Gudmar Thorleifsson Anna Helgadottir Solveig Gretarsdottir Gudmundur Norddahl Sridharan Rajamani Bjarni Torfason Atli S Valgardsson Jon T Sverrisson Vinicius Tragante Oddgeir L Holmen Folkert W Asselbergs Dan M Roden Dawood Darbar Terje R Pedersen Marc S Sabatine Cristen J Willer Maja-Lisa Løchen Bjarni V Halldorsson Ingileif Jonsdottir Kristian Hveem David O Arnar Unnur Thorsteinsdottir Daniel F Gudbjartsson Hilma Holm Kari Stefansson

Commun Biol 2018 12;1:68. Epub 2018 Jun 12.

deCODE genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s42003-018-0068-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123807PMC
June 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 05;50(5):765-766

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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May 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 05;50(5):766-767

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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May 2018

A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin.

Authors:
Gudjon R Oskarsson Ragnar P Kristjansson Amy L Lee Gardar Sveinbjornsson Magnus K Magnusson Erna V Ivarsdottir Stefania Benonisdottir Asmundur Oddsson Olafur B Davidsson Jona Saemundsdottir Gisli H Halldorsson Joseph Arthur Gudny A Arnadottir Gisli Masson Brynjar O Jensson Hilma Holm Isleifur Olafsson Pall T Onundarson Daniel F Gudbjartsson Gudmundur L Norddahl Unnur Thorsteinsdottir Patrick Sulem Kari Stefansson

Commun Biol 2018 17;1:49. Epub 2018 May 17.

deCODE genetics/Amgen, Inc, 101, Reykjavik, Iceland.

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http://www.nature.com/articles/s42003-018-0053-3
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123817PMC
May 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

Authors:
Eleni Zengini Konstantinos Hatzikotoulas Ioanna Tachmazidou Julia Steinberg Fernando P Hartwig Lorraine Southam Sophie Hackinger Cindy G Boer Unnur Styrkarsdottir Arthur Gilly Daniel Suveges Britt Killian Thorvaldur Ingvarsson Helgi Jonsson George C Babis Andrew McCaskie Andre G Uitterlinden Joyce B J van Meurs Unnur Thorsteinsdottir Kari Stefansson George Davey Smith Jeremy M Wilkinson Eleftheria Zeggini

Nat Genet 2018 04 20;50(4):549-558. Epub 2018 Mar 20.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/s41588-018-0079-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896734PMC
April 2018

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

Authors:
Kerrin S Small Marijana Todorčević Mete Civelek Julia S El-Sayed Moustafa Xiao Wang Michelle M Simon Juan Fernandez-Tajes Anubha Mahajan Momoko Horikoshi Alison Hugill Craig A Glastonbury Lydia Quaye Matt J Neville Siddharth Sethi Marianne Yon Calvin Pan Nam Che Ana Viñuela Pei-Chien Tsai Abhishek Nag Alfonso Buil Gudmar Thorleifsson Avanthi Raghavan Qiurong Ding Andrew P Morris Jordana T Bell Unnur Thorsteinsdottir Kari Stefansson Markku Laakso Ingrid Dahlman Peter Arner Anna L Gloyn Kiran Musunuru Aldons J Lusis Roger D Cox Fredrik Karpe Mark I McCarthy

Nat Genet 2018 04 9;50(4):572-580. Epub 2018 Apr 9.

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935235PMC
April 2018

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Authors:
Anubha Mahajan Jennifer Wessel Sara M Willems Wei Zhao Neil R Robertson Audrey Y Chu Wei Gan Hidetoshi Kitajima Daniel Taliun N William Rayner Xiuqing Guo Yingchang Lu Man Li Richard A Jensen Yao Hu Shaofeng Huo Kurt K Lohman Weihua Zhang James P Cook Bram Peter Prins Jason Flannick Niels Grarup Vassily Vladimirovich Trubetskoy Jasmina Kravic Young Jin Kim Denis V Rybin Hanieh Yaghootkar Martina Müller-Nurasyid Karina Meidtner Ruifang Li-Gao Tibor V Varga Jonathan Marten Jin Li Albert Vernon Smith Ping An Symen Ligthart Stefan Gustafsson Giovanni Malerba Ayse Demirkan Juan Fernandez Tajes Valgerdur Steinthorsdottir Matthias Wuttke Cécile Lecoeur Michael Preuss Lawrence F Bielak Marielisa Graff Heather M Highland Anne E Justice Dajiang J Liu Eirini Marouli Gina Marie Peloso Helen R Warren Saima Afaq Shoaib Afzal Emma Ahlqvist Peter Almgren Najaf Amin Lia B Bang Alain G Bertoni Cristina Bombieri Jette Bork-Jensen Ivan Brandslund Jennifer A Brody Noël P Burtt Mickaël Canouil Yii-Der Ida Chen Yoon Shin Cho Cramer Christensen Sophie V Eastwood Kai-Uwe Eckardt Krista Fischer Giovanni Gambaro Vilmantas Giedraitis Megan L Grove Hugoline G de Haan Sophie Hackinger Yang Hai Sohee Han Anne Tybjærg-Hansen Marie-France Hivert Bo Isomaa Susanne Jäger Marit E Jørgensen Torben Jørgensen Annemari Käräjämäki Bong-Jo Kim Sung Soo Kim Heikki A Koistinen Peter Kovacs Jennifer Kriebel Florian Kronenberg Kristi Läll Leslie A Lange Jung-Jin Lee Benjamin Lehne Huaixing Li Keng-Hung Lin Allan Linneberg Ching-Ti Liu Jun Liu Marie Loh Reedik Mägi Vasiliki Mamakou Roberta McKean-Cowdin Girish Nadkarni Matt Neville Sune F Nielsen Ioanna Ntalla Patricia A Peyser Wolfgang Rathmann Kenneth Rice Stephen S Rich Line Rode Olov Rolandsson Sebastian Schönherr Elizabeth Selvin Kerrin S Small Alena Stančáková Praveen Surendran Kent D Taylor Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Adrienne Tin Anke Tönjes Anette Varbo Daniel R Witte Andrew R Wood Pranav Yajnik Jie Yao Loïc Yengo Robin Young Philippe Amouyel Heiner Boeing Eric Boerwinkle Erwin P Bottinger Rajiv Chowdhury Francis S Collins George Dedoussis Abbas Dehghan Panos Deloukas Marco M Ferrario Jean Ferrières Jose C Florez Philippe Frossard Vilmundur Gudnason Tamara B Harris Susan R Heckbert Joanna M M Howson Martin Ingelsson Sekar Kathiresan Frank Kee Johanna Kuusisto Claudia Langenberg Lenore J Launer Cecilia M Lindgren Satu Männistö Thomas Meitinger Olle Melander Karen L Mohlke Marie Moitry Andrew D Morris Alison D Murray Renée de Mutsert Marju Orho-Melander Katharine R Owen Markus Perola Annette Peters Michael A Province Asif Rasheed Paul M Ridker Fernando Rivadineira Frits R Rosendaal Anders H Rosengren Veikko Salomaa Wayne H-H Sheu Rob Sladek Blair H Smith Konstantin Strauch André G Uitterlinden Rohit Varma Cristen J Willer Matthias Blüher Adam S Butterworth John Campbell Chambers Daniel I Chasman John Danesh Cornelia van Duijn Josée Dupuis Oscar H Franco Paul W Franks Philippe Froguel Harald Grallert Leif Groop Bok-Ghee Han Torben Hansen Andrew T Hattersley Caroline Hayward Erik Ingelsson Sharon L R Kardia Fredrik Karpe Jaspal Singh Kooner Anna Köttgen Kari Kuulasmaa Markku Laakso Xu Lin Lars Lind Yongmei Liu Ruth J F Loos Jonathan Marchini Andres Metspalu Dennis Mook-Kanamori Børge G Nordestgaard Colin N A Palmer James S Pankow Oluf Pedersen Bruce M Psaty Rainer Rauramaa Naveed Sattar Matthias B Schulze Nicole Soranzo Timothy D Spector Kari Stefansson Michael Stumvoll Unnur Thorsteinsdottir Tiinamaija Tuomi Jaakko Tuomilehto Nicholas J Wareham James G Wilson Eleftheria Zeggini Robert A Scott Inês Barroso Timothy M Frayling Mark O Goodarzi James B Meigs Michael Boehnke Danish Saleheen Andrew P Morris Jerome I Rotter Mark I McCarthy

Nat Genet 2018 04 9;50(4):559-571. Epub 2018 Apr 9.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898373PMC
April 2018

Genome-wide analysis yields new loci associating with aortic valve stenosis.

Authors:
Anna Helgadottir Gudmar Thorleifsson Solveig Gretarsdottir Olafur A Stefansson Vinicius Tragante Rosa B Thorolfsdottir Ingileif Jonsdottir Thorsteinn Bjornsson Valgerdur Steinthorsdottir Niek Verweij Jonas B Nielsen Wei Zhou Lasse Folkersen Andreas Martinsson Mahyar Heydarpour Siddharth Prakash Gylfi Oskarsson Tomas Gudbjartsson Arnar Geirsson Isleifur Olafsson Emil L Sigurdsson Peter Almgren Olle Melander Anders Franco-Cereceda Anders Hamsten Lars Fritsche Maoxuan Lin Bo Yang Whitney Hornsby Dongchuan Guo Chad M Brummett Gonçalo Abecasis Michael Mathis Dianna Milewicz Simon C Body Per Eriksson Cristen J Willer Kristian Hveem Christopher Newton-Cheh J Gustav Smith Ragnar Danielsen Gudmundur Thorgeirsson Unnur Thorsteinsdottir Daniel F Gudbjartsson Hilma Holm Kari Stefansson

Nat Commun 2018 03 7;9(1):987. Epub 2018 Mar 7.

deCODE genetics/Amgen Inc., Reykjavik, 101, Iceland.

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http://dx.doi.org/10.1038/s41467-018-03252-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840367PMC
March 2018

Comparison of the effect of allopurinol and febuxostat on urinary 2,8-dihydroxyadenine excretion in patients with Adenine phosphoribosyltransferase deficiency (APRTd): A clinical trial.

Authors:
Vidar O Edvardsson Hrafnhildur L Runolfsdottir Unnur A Thorsteinsdottir Inger M Sch Agustsdottir G Steinunn Oddsdottir Finnur Eiriksson David S Goldfarb Margret Thorsteinsdottir Runolfur Palsson

Eur J Intern Med 2018 02 12;48:75-79. Epub 2017 Dec 12.

Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland; Division of Nephrology, Internal Medicine Services, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2017.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817015PMC
February 2018

A rare missense variant in associates with lower cholesterol levels.

Authors:
Aimee M Deaton Patrick Sulem Paul Nioi Stefania Benonisdottir Lucas D Ward Olafur B Davidsson Socheata Lao Anna Helgadottir Fan Fan Brynjar O Jensson Gudmundur L Norddahl Aslaug Jonasdottir Adalbjorg Jonasdottir Asgeir Sigurdsson Ragnar P Kristjansson Asmundur Oddsson Gudny A Arnadottir Hakon Jonsson Isleifur Olafsson Gudmundur I Eyjolfsson Olof Sigurdardottir Einar S Bjornsson Sigurdur Olafsson Thora Steingrimsdottir Thorunn Rafnar Gudmundur Thorgeirsson Gisli Masson Gudmar Thorleifsson Daniel F Gudbjartsson Hilma Holm Unnur Thorsteinsdottir Kari Stefansson

Commun Biol 2018 8;1:14. Epub 2018 Feb 8.

deCODE Genetics/Amgen, Inc., Reykjavik, 101, Iceland.

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http://dx.doi.org/10.1038/s42003-018-0015-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123719PMC
February 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2018 01 22;50(1):26-41. Epub 2017 Dec 22.

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-017-0011-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945951PMC
January 2018

The nature of nurture: Effects of parental genotypes.

Authors:
Augustine Kong Gudmar Thorleifsson Michael L Frigge Bjarni J Vilhjalmsson Alexander I Young Thorgeir E Thorgeirsson Stefania Benonisdottir Asmundur Oddsson Bjarni V Halldorsson Gisli Masson Daniel F Gudbjartsson Agnar Helgason Gyda Bjornsdottir Unnur Thorsteinsdottir Kari Stefansson

Science 2018 Jan;359(6374):424-428

deCODE genetics/Amgen, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1126/science.aan6877DOI Listing
January 2018

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.

Authors:
Robert A Scott Laura J Scott Reedik Mägi Letizia Marullo Kyle J Gaulton Marika Kaakinen Natalia Pervjakova Tune H Pers Andrew D Johnson John D Eicher Anne U Jackson Teresa Ferreira Yeji Lee Clement Ma Valgerdur Steinthorsdottir Gudmar Thorleifsson Lu Qi Natalie R Van Zuydam Anubha Mahajan Han Chen Peter Almgren Ben F Voight Harald Grallert Martina Müller-Nurasyid Janina S Ried Nigel W Rayner Neil Robertson Lennart C Karssen Elisabeth M van Leeuwen Sara M Willems Christian Fuchsberger Phoenix Kwan Tanya M Teslovich Pritam Chanda Man Li Yingchang Lu Christian Dina Dorothee Thuillier Loic Yengo Longda Jiang Thomas Sparso Hans A Kestler Himanshu Chheda Lewin Eisele Stefan Gustafsson Mattias Frånberg Rona J Strawbridge Rafn Benediktsson Astradur B Hreidarsson Augustine Kong Gunnar Sigurðsson Nicola D Kerrison Jian'an Luan Liming Liang Thomas Meitinger Michael Roden Barbara Thorand Tõnu Esko Evelin Mihailov Caroline Fox Ching-Ti Liu Denis Rybin Bo Isomaa Valeriya Lyssenko Tiinamaija Tuomi David J Couper James S Pankow Niels Grarup Christian T Have Marit E Jørgensen Torben Jørgensen Allan Linneberg Marilyn C Cornelis Rob M van Dam David J Hunter Peter Kraft Qi Sun Sarah Edkins Katharine R Owen John R B Perry Andrew R Wood Eleftheria Zeggini Juan Tajes-Fernandes Goncalo R Abecasis Lori L Bonnycastle Peter S Chines Heather M Stringham Heikki A Koistinen Leena Kinnunen Bengt Sennblad Thomas W Mühleisen Markus M Nöthen Sonali Pechlivanis Damiano Baldassarre Karl Gertow Steve E Humphries Elena Tremoli Norman Klopp Julia Meyer Gerald Steinbach Roman Wennauer Johan G Eriksson Satu Mӓnnistö Leena Peltonen Emmi Tikkanen Guillaume Charpentier Elodie Eury Stéphane Lobbens Bruna Gigante Karin Leander Olga McLeod Erwin P Bottinger Omri Gottesman Douglas Ruderfer Matthias Blüher Peter Kovacs Anke Tonjes Nisa M Maruthur Chiara Scapoli Raimund Erbel Karl-Heinz Jöckel Susanne Moebus Ulf de Faire Anders Hamsten Michael Stumvoll Panagiotis Deloukas Peter J Donnelly Timothy M Frayling Andrew T Hattersley Samuli Ripatti Veikko Salomaa Nancy L Pedersen Bernhard O Boehm Richard N Bergman Francis S Collins Karen L Mohlke Jaakko Tuomilehto Torben Hansen Oluf Pedersen Inês Barroso Lars Lannfelt Erik Ingelsson Lars Lind Cecilia M Lindgren Stephane Cauchi Philippe Froguel Ruth J F Loos Beverley Balkau Heiner Boeing Paul W Franks Aurelio Barricarte Gurrea Domenico Palli Yvonne T van der Schouw David Altshuler Leif C Groop Claudia Langenberg Nicholas J Wareham Eric Sijbrands Cornelia M van Duijn Jose C Florez James B Meigs Eric Boerwinkle Christian Gieger Konstantin Strauch Andres Metspalu Andrew D Morris Colin N A Palmer Frank B Hu Unnur Thorsteinsdottir Kari Stefansson Josée Dupuis Andrew P Morris Michael Boehnke Mark I McCarthy Inga Prokopenko

Diabetes 2017 11 31;66(11):2888-2902. Epub 2017 May 31.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db16-1253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652602PMC
November 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

COPA syndrome in an Icelandic family caused by a recurrent missense mutation in COPA.

Authors:
Brynjar O Jensson Sif Hansdottir Gudny A Arnadottir Gerald Sulem Ragnar P Kristjansson Asmundur Oddsson Stefania Benonisdottir Hakon Jonsson Agnar Helgason Jona Saemundsdottir Olafur T Magnusson Gisli Masson Gudmundur A Thorisson Adalbjorg Jonasdottir Aslaug Jonasdottir Asgeir Sigurdsson Ingileif Jonsdottir Vigdis Petursdottir Jon R Kristinsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Reynir Arngrimsson Patrick Sulem Gunnar Gudmundsson Kari Stefansson

BMC Med Genet 2017 11 14;18(1):129. Epub 2017 Nov 14.

deCODE Genetics/Amgen, Inc, Sturlugata 8, 101, Reykjavik, Iceland.

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https://bmcmedgenet.biomedcentral.com/articles/10.1186/s1288
Publisher Site
http://dx.doi.org/10.1186/s12881-017-0490-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686906PMC
November 2017

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus.

Authors:
Sophie Hackinger Katerina Trajanoska Unnur Styrkarsdottir Eleni Zengini Julia Steinberg Graham R S Ritchie Konstantinos Hatzikotoulas Arthur Gilly Evangelos Evangelou John P Kemp David Evans Thorvaldur Ingvarsson Helgi Jonsson Unnur Thorsteinsdottir Kari Stefansson Andrew W McCaskie Roger A Brooks Jeremy M Wilkinson Fernando Rivadeneira Eleftheria Zeggini

Hum Mol Genet 2017 10;26(19):3850-3858

Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, UK.

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http://dx.doi.org/10.1093/hmg/ddx285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886098PMC
October 2017

Compound heterozygous mutations in UBA5 causing early-onset epileptic encephalopathy in two sisters.

Authors:
Gudny A Arnadottir Brynjar O Jensson Sigurdur E Marelsson Gerald Sulem Asmundur Oddsson Ragnar P Kristjansson Stefania Benonisdottir Sigurjon A Gudjonsson Gisli Masson Gudmundur A Thorisson Jona Saemundsdottir Olafur Th Magnusson Adalbjorg Jonasdottir Aslaug Jonasdottir Asgeir Sigurdsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Reynir Arngrimsson Patrick Sulem Kari Stefansson

BMC Med Genet 2017 10 2;18(1):103. Epub 2017 Oct 2.

deCODE Genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.

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http://dx.doi.org/10.1186/s12881-017-0466-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623963PMC
October 2017

A Missense Variant in PLEC Increases Risk of Atrial Fibrillation.

Authors:
Rosa B Thorolfsdottir Gardar Sveinbjornsson Patrick Sulem Anna Helgadottir Solveig Gretarsdottir Stefania Benonisdottir Audur Magnusdottir Olafur B Davidsson Sridharan Rajamani Dan M Roden Dawood Darbar Terje R Pedersen Marc S Sabatine Ingileif Jonsdottir David O Arnar Unnur Thorsteinsdottir Daniel F Gudbjartsson Hilma Holm Kari Stefansson

J Am Coll Cardiol 2017 Oct;70(17):2157-2168

deCODE genetics/Amgen, Inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704994PMC
October 2017

Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability.

Authors:
Erna V Ivarsdottir Valgerdur Steinthorsdottir Maryam S Daneshpour Gudmar Thorleifsson Patrick Sulem Hilma Holm Snaevar Sigurdsson Astradur B Hreidarsson Gunnar Sigurdsson Ragnar Bjarnason Arni V Thorsson Rafn Benediktsson Gudmundur Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Sirous Zeinali Fereidoun Azizi Unnur Thorsteinsdottir Daniel F Gudbjartsson Kari Stefansson

Nat Genet 2017 Sep 7;49(9):1398-1402. Epub 2017 Aug 7.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.3928DOI Listing
September 2017

Whole genome characterization of sequence diversity of 15,220 Icelanders.

Authors:
Hákon Jónsson Patrick Sulem Birte Kehr Snaedis Kristmundsdottir Florian Zink Eirikur Hjartarson Marteinn T Hardarson Kristjan E Hjorleifsson Hannes P Eggertsson Sigurjon Axel Gudjonsson Lucas D Ward Gudny A Arnadottir Einar A Helgason Hannes Helgason Arnaldur Gylfason Adalbjorg Jonasdottir Aslaug Jonasdottir Thorunn Rafnar Soren Besenbacher Michael L Frigge Simon N Stacey Olafur Th Magnusson Unnur Thorsteinsdottir Gisli Masson Augustine Kong Bjarni V Halldorsson Agnar Helgason Daniel F Gudbjartsson Kari Stefansson

Sci Data 2017 09 21;4:170115. Epub 2017 Sep 21.

deCODE genetics/Amgen Inc., Sturlugata 8, Reykjavik 101, Iceland.

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http://dx.doi.org/10.1038/sdata.2017.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607473PMC
September 2017

Parental influence on human germline de novo mutations in 1,548 trios from Iceland.

Authors:
Hákon Jónsson Patrick Sulem Birte Kehr Snaedis Kristmundsdottir Florian Zink Eirikur Hjartarson Marteinn T Hardarson Kristjan E Hjorleifsson Hannes P Eggertsson Sigurjon Axel Gudjonsson Lucas D Ward Gudny A Arnadottir Einar A Helgason Hannes Helgason Arnaldur Gylfason Adalbjorg Jonasdottir Aslaug Jonasdottir Thorunn Rafnar Mike Frigge Simon N Stacey Olafur Th Magnusson Unnur Thorsteinsdottir Gisli Masson Augustine Kong Bjarni V Halldorsson Agnar Helgason Daniel F Gudbjartsson Kari Stefansson

Nature 2017 09 20;549(7673):519-522. Epub 2017 Sep 20.

deCODE genetics/Amgen Inc., 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/nature24018DOI Listing
September 2017

Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly.

Authors:
Florian Zink Simon N Stacey Gudmundur L Norddahl Michael L Frigge Olafur T Magnusson Ingileif Jonsdottir Thorgeir E Thorgeirsson Asgeir Sigurdsson Sigurjon A Gudjonsson Julius Gudmundsson Jon G Jonasson Laufey Tryggvadottir Thorvaldur Jonsson Agnar Helgason Arnaldur Gylfason Patrick Sulem Thorunn Rafnar Unnur Thorsteinsdottir Daniel F Gudbjartsson Gisli Masson Augustine Kong Kari Stefansson

Blood 2017 08 8;130(6):742-752. Epub 2017 May 8.

deCODE genetics/AMGEN, Reykjavik, Iceland.

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http://dx.doi.org/10.1182/blood-2017-02-769869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553576PMC
August 2017

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.

Authors:
Ralph McGinnis Valgerdur Steinthorsdottir Nicholas O Williams Gudmar Thorleifsson Scott Shooter Sigrun Hjartardottir Suzannah Bumpstead Lilja Stefansdottir Lucy Hildyard Jon K Sigurdsson John P Kemp Gabriela B Silva Liv Cecilie V Thomsen Tiina Jääskeläinen Eero Kajantie Sally Chappell Noor Kalsheker Ashley Moffett Susan Hiby Wai Kwong Lee Sandosh Padmanabhan Nigel A B Simpson Vivien A Dolby Eleonora Staines-Urias Stephanie M Engel Anita Haugan Lill Trogstad Gulnara Svyatova Nodira Zakhidova Dilbar Najmutdinova Anna F Dominiczak Håkon K Gjessing Juan P Casas Frank Dudbridge James J Walker Fiona Broughton Pipkin Unnur Thorsteinsdottir Reynir T Geirsson Debbie A Lawlor Ann-Charlotte Iversen Per Magnus Hannele Laivuori Kari Stefansson Linda Morgan

Nat Genet 2017 Aug 19;49(8):1255-1260. Epub 2017 Jun 19.

School of Life Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1038/ng.3895DOI Listing
August 2017

Identification of sequence variants influencing immunoglobulin levels.

Authors:
Stefan Jonsson Gardar Sveinbjornsson Aitzkoa Lopez de Lapuente Portilla Bhairavi Swaminathan Rosina Plomp Gillian Dekkers Ram Ajore Mina Ali Arthur E H Bentlage Evelina Elmér Gudmundur I Eyjolfsson Sigurjon A Gudjonsson Urban Gullberg Arnaldur Gylfason Bjarni V Halldorsson Markus Hansson Hilma Holm Åsa Johansson Ellinor Johnsson Aslaug Jonasdottir Bjorn R Ludviksson Asmundur Oddsson Isleifur Olafsson Sigurgeir Olafsson Olof Sigurdardottir Asgeir Sigurdsson Lilja Stefansdottir Gisli Masson Patrick Sulem Manfred Wuhrer Anna-Karin Wihlborg Gudmar Thorleifsson Daniel F Gudbjartsson Unnur Thorsteinsdottir Gestur Vidarsson Ingileif Jonsdottir Björn Nilsson Kari Stefansson

Nat Genet 2017 Aug 19;49(8):1182-1191. Epub 2017 Jun 19.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.3897DOI Listing
August 2017

Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.

Authors:
Sigurgeir Olafsson Pernilla Stridh Steffan Daniël Bos Andres Ingason Jack Euesden Patrick Sulem Gudmar Thorleifsson Omar Gustafsson Ari Johannesson Arni J Geirsson Arni V Thorsson Bardur Sigurgeirsson Bjorn Runar Ludviksson Elias Olafsson Helga Kristjansdottir Jon G Jonasson Jon Hjaltalin Olafsson Kjartan B Orvar Rafn Benediktsson Ragnar Bjarnason Sjofn Kristjansdottir Thorarinn Gislason Trausti Valdimarsson Evgenia Mikaelsdottir Snaevar Sigurdsson Stefan Jonsson Thorunn Rafnar Dag Aarsland Srdjan Djurovic Tormod Fladby Gun Peggy Knudsen Elisabeth G Celius Kjell-Morten Myhr Gerdur Grondal Kristjan Steinsson Helgi Valdimarsson Sigurdur Bjornsson Unnur S Bjornsdottir Einar S Bjornsson Bjorn Nilsson Ole A Andreassen Lars Alfredsson Jan Hillert Ingrid Skelton Kockum Gisli Masson Unnur Thorsteinsdottir Daniel F Gudbjartsson Hreinn Stefansson Haukur Hjaltason Hanne F Harbo Tomas Olsson Ingileif Jonsdottir Kari Stefansson

NPJ Genom Med 2017 8;2:24. Epub 2017 Aug 8.

deCODE genetics/Amgen, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/s41525-017-0027-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677966PMC
August 2017

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

Authors:
Tin Aung Mineo Ozaki Mei Chin Lee Ursula Schlötzer-Schrehardt Gudmar Thorleifsson Takanori Mizoguchi Robert P Igo Aravind Haripriya Susan E Williams Yury S Astakhov Andrew C Orr Kathryn P Burdon Satoko Nakano Kazuhiko Mori Khaled Abu-Amero Michael Hauser Zheng Li Gopalakrishnan Prakadeeswari Jessica N Cooke Bailey Alina Popa Cherecheanu Jae H Kang Sarah Nelson Ken Hayashi Shin-Ichi Manabe Shigeyasu Kazama Tomasz Zarnowski Kenji Inoue Murat Irkec Miguel Coca-Prados Kazuhisa Sugiyama Irma Järvelä Patricio Schlottmann S Fabian Lerner Hasnaa Lamari Yildirim Nilgün Mukharram Bikbov Ki Ho Park Soon Cheol Cha Kenji Yamashiro Juan C Zenteno Jost B Jonas Rajesh S Kumar Shamira A Perera Anita S Y Chan Nino Kobakhidze Ronnie George Lingam Vijaya Tan Do Deepak P Edward Lourdes de Juan Marcos Mohammad Pakravan Sasan Moghimi Ryuichi Ideta Daniella Bach-Holm Per Kappelgaard Barbara Wirostko Samuel Thomas Daniel Gaston Karen Bedard Wenda L Greer Zhenglin Yang Xueyi Chen Lulin Huang Jinghong Sang Hongyan Jia Liyun Jia Chunyan Qiao Hui Zhang Xuyang Liu Bowen Zhao Ya-Xing Wang Liang Xu Stéphanie Leruez Pascal Reynier George Chichua Sergo Tabagari Steffen Uebe Matthias Zenkel Daniel Berner Georg Mossböck Nicole Weisschuh Ursula Hoja Ulrich-Christoph Welge-Luessen Christian Mardin Panayiota Founti Anthi Chatzikyriakidou Theofanis Pappas Eleftherios Anastasopoulos Alexandros Lambropoulos Arkasubhra Ghosh Rohit Shetty Natalia Porporato Vijayan Saravanan Rengaraj Venkatesh Chandrashekaran Shivkumar Narendran Kalpana Sripriya Sarangapani Mozhgan R Kanavi Afsaneh Naderi Beni Shahin Yazdani Alireza Lashay Homa Naderifar Nassim Khatibi Antonio Fea Carlo Lavia Laura Dallorto Teresa Rolle Paolo Frezzotti Daniela Paoli Erika Salvi Paolo Manunta Yosai Mori Kazunori Miyata Tomomi Higashide Etsuo Chihara Satoshi Ishiko Akitoshi Yoshida Masahide Yanagi Yoshiaki Kiuchi Tsutomu Ohashi Toshiya Sakurai Takako Sugimoto Hideki Chuman Makoto Aihara Masaru Inatani Masahiro Miyake Norimoto Gotoh Fumihiko Matsuda Nagahisa Yoshimura Yoko Ikeda Morio Ueno Chie Sotozono Jin Wook Jeoung Min Sagong Kyu Hyung Park Jeeyun Ahn Marisa Cruz-Aguilar Sidi M Ezzouhairi Abderrahman Rafei Yaan Fun Chong Xiao Yu Ng Shuang Ru Goh Yueming Chen Victor H K Yong Muhammad Imran Khan Olusola O Olawoye Adeyinka O Ashaye Idakwo Ugbede Adeola Onakoya Nkiru Kizor-Akaraiwe Chaiwat Teekhasaenee Yanin Suwan Wasu Supakontanasan Suhanya Okeke Nkechi J Uche Ifeoma Asimadu Humaira Ayub Farah Akhtar Ewa Kosior-Jarecka Urszula Lukasik Ignacio Lischinsky Vania Castro Rodolfo Perez Grossmann Gordana Sunaric Megevand Sylvain Roy Edward Dervan Eoin Silke Aparna Rao Priti Sahay Pablo Fornero Osvaldo Cuello Delia Sivori Tamara Zompa Richard A Mills Emmanuelle Souzeau Paul Mitchell Jie Jin Wang Alex W Hewitt Michael Coote Jonathan G Crowston Sergei Y Astakhov Eugeny L Akopov Anton Emelyanov Vera Vysochinskaya Gyulli Kazakbaeva Rinat Fayzrakhmanov Saleh A Al-Obeidan Ohoud Owaidhah Leyla Ali Aljasim Balram Chowbay Jia Nee Foo Raphael Q Soh Kar Seng Sim Zhicheng Xie Augustine W O Cheong Shi Qi Mok Hui Meng Soo Xiao Yin Chen Su Qin Peh Khai Koon Heng Rahat Husain Su-Ling Ho Axel M Hillmer Ching-Yu Cheng Francisco A Escudero-Domínguez Rogelio González-Sarmiento Frederico Martinon-Torres Antonio Salas Kessara Pathanapitoon Linda Hansapinyo Boonsong Wanichwecharugruang Naris Kitnarong Anavaj Sakuntabhai Hip X Nguyn Giang T T Nguyn Trình V Nguyn Werner Zenz Alexander Binder Daniela S Klobassa Martin L Hibberd Sonia Davila Stefan Herms Markus M Nöthen Susanne Moebus Robyn M Rautenbach Ari Ziskind Trevor R Carmichael Michele Ramsay Lydia Álvarez Montserrat García Héctor González-Iglesias Pedro P Rodríguez-Calvo Luis Fernández-Vega Cueto Çilingir Oguz Nevbahar Tamcelik Eray Atalay Bilge Batu Dilek Aktas Burcu Kasım M Roy Wilson Anne L Coleman Yutao Liu Pratap Challa Leon Herndon Rachel W Kuchtey John Kuchtey Karen Curtin Craig J Chaya Alan Crandall Linda M Zangwill Tien Yin Wong Masakazu Nakano Shigeru Kinoshita Anneke I den Hollander Eija Vesti John H Fingert Richard K Lee Arthur J Sit Bradford J Shingleton Ningli Wang Daniele Cusi Raheel Qamar Peter Kraft Margaret A Pericak-Vance Soumya Raychaudhuri Steffen Heegaard Tero Kivelä André Reis Friedrich E Kruse Robert N Weinreb Louis R Pasquale Jonathan L Haines Unnur Thorsteinsdottir Fridbert Jonasson R Rand Allingham Dan Milea Robert Ritch Toshiaki Kubota Kei Tashiro Eranga N Vithana Shazia Micheal Fotis Topouzis Jamie E Craig Michael Dubina Periasamy Sundaresan Kari Stefansson Janey L Wiggs Francesca Pasutto Chiea Chuen Khor

Nat Genet 2017 07 29;49(7):993-1004. Epub 2017 May 29.

Singapore Eye Research Institute, Singapore.

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http://dx.doi.org/10.1038/ng.3875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685441PMC
July 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis.

Authors:
Unnur Styrkarsdottir Hannes Helgason Asgeir Sigurdsson Gudmundur L Norddahl Arna B Agustsdottir Louise N Reynard Amanda Villalvilla Gisli H Halldorsson Aslaug Jonasdottir Audur Magnusdottir Asmundur Oddson Gerald Sulem Florian Zink Gardar Sveinbjornsson Agnar Helgason Hrefna S Johannsdottir Anna Helgadottir Hreinn Stefansson Solveig Gretarsdottir Thorunn Rafnar Ina S Almdahl Anne Brækhus Tormod Fladby Geir Selbæk Farhad Hosseinpanah Fereidoun Azizi Jung Min Koh Nelson L S Tang Maryams Danesphour Jose I Mayordomo Corrine Welt Peter S Braund Nilesh J Samani Lambertus A Kiemeney L Stefan Lohmander Claus Christiansen Ole A Andreassen arcOGEN Consortium Olafur Magnusson Gisli Masson Augustine Kong Ingileif Jonsdottir Daniel Gudbjartsson Patrick Sulem Helgi Jonsson John Loughlin Thorvaldur Ingvarsson Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2017 07;49(8):1286

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http://dx.doi.org/10.1038/ng0817-1286bDOI Listing
July 2017

A rare splice donor mutation in the haptoglobin gene associates with blood lipid levels and coronary artery disease.

Authors:
Eythor Bjornsson Hannes Helgason Gisli Halldorsson Anna Helgadottir Arnaldur Gylfason Birte Kehr Adalbjorg Jonasdottir Aslaug Jonasdottir Asgeir Sigurdsson Asmundur Oddsson Gudmar Thorleifsson Olafur Th Magnusson Solveig Gretarsdottir Florian Zink Ragnar P Kristjansson Margret Asgeirsdottir Dorine W Swinkels Lambertus A Kiemeney Gudmundur I Eyjolfsson Olof Sigurdardottir Gisli Masson Isleifur Olafsson Gudmundur Thorgeirsson Hilma Holm Unnur Thorsteinsdottir Daniel F Gudbjartsson Patrick Sulem Kari Stefansson

Hum Mol Genet 2017 06;26(12):2364-2376

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1093/hmg/ddx123DOI Listing
June 2017

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.

Authors:
Snaevar Sigurdsson Kristjan F Alexandersson Patrick Sulem Bjarke Feenstra Steinunn Gudmundsdottir Gisli H Halldorsson Sigurgeir Olafsson Asgeir Sigurdsson Thorunn Rafnar Thorgeir Thorgeirsson Erik Sørensen Andreas Nordholm-Carstensen Jakob Burcharth Jens Andersen Henrik Stig Jørgensen Emma Possfelt-Møller Henrik Ullum Gudmar Thorleifsson Gisli Masson Unnur Thorsteinsdottir Mads Melbye Daniel F Gudbjartsson Tryggvi Stefansson Ingileif Jonsdottir Kari Stefansson

Nat Commun 2017 06 6;8:15789. Epub 2017 Jun 6.

deCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ncomms15789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467205PMC
June 2017

Sequence variant at 4q25 near PITX2 associates with appendicitis.

Authors:
Ragnar P Kristjansson Stefania Benonisdottir Asmundur Oddsson Tessel E Galesloot Gudmar Thorleifsson Katja K Aben Olafur B Davidsson Stefan Jonsson Gudny A Arnadottir Brynjar O Jensson G Bragi Walters Jon K Sigurdsson Snaevar Sigurdsson Hilma Holm David O Arnar Gudmundur Thorgeirsson Kristin Alexiusdottir Ingileif Jonsdottir Unnur Thorsteinsdottir Lambertus A Kiemeney Thorvaldur Jonsson Daniel F Gudbjartsson Thorunn Rafnar Patrick Sulem Kari Stefansson

Sci Rep 2017 06 8;7(1):3119. Epub 2017 Jun 8.

deCODE genetics/Amgen, Inc, Reykjavik, 101, Iceland.

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http://dx.doi.org/10.1038/s41598-017-03353-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465083PMC
June 2017

Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis.

Authors:
Unnur Styrkarsdottir Hannes Helgason Asgeir Sigurdsson Gudmundur L Norddahl Arna B Agustsdottir Louise N Reynard Amanda Villalvilla Gisli H Halldorsson Aslaug Jonasdottir Audur Magnusdottir Asmundur Oddson Gerald Sulem Florian Zink Gardar Sveinbjornsson Agnar Helgason Hrefna S Johannsdottir Anna Helgadottir Hreinn Stefansson Solveig Gretarsdottir Thorunn Rafnar Ina S Almdahl Anne Brækhus Tormod Fladby Geir Selbæk Farhad Hosseinpanah Fereidoun Azizi Jung Min Koh Nelson L S Tang Maryam S Daneshpour Jose I Mayordomo Corrine Welt Peter S Braund Nilesh J Samani Lambertus A Kiemeney L Stefan Lohmander Claus Christiansen Ole A Andreassen Olafur Magnusson Gisli Masson Augustine Kong Ingileif Jonsdottir Daniel Gudbjartsson Patrick Sulem Helgi Jonsson John Loughlin Thorvaldur Ingvarsson Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2017 May 20;49(5):801-805. Epub 2017 Mar 20.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.3816DOI Listing
May 2017

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.

Authors:
Yadav Sapkota Valgerdur Steinthorsdottir Andrew P Morris Amelie Fassbender Nilufer Rahmioglu Immaculata De Vivo Julie E Buring Futao Zhang Todd L Edwards Sarah Jones Dorien O Daniëlle Peterse Kathryn M Rexrode Paul M Ridker Andrew J Schork Stuart MacGregor Nicholas G Martin Christian M Becker Sosuke Adachi Kosuke Yoshihara Takayuki Enomoto Atsushi Takahashi Yoichiro Kamatani Koichi Matsuda Michiaki Kubo Gudmar Thorleifsson Reynir T Geirsson Unnur Thorsteinsdottir Leanne M Wallace Jian Yang Digna R Velez Edwards Mette Nyegaard Siew-Kee Low Krina T Zondervan Stacey A Missmer Thomas D'Hooghe Grant W Montgomery Daniel I Chasman Kari Stefansson Joyce Y Tung Dale R Nyholt

Nat Commun 2017 05 24;8:15539. Epub 2017 May 24.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.

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http://dx.doi.org/10.1038/ncomms15539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458088PMC
May 2017

Diversity in non-repetitive human sequences not found in the reference genome.

Authors:
Birte Kehr Anna Helgadottir Pall Melsted Hakon Jonsson Hannes Helgason Adalbjörg Jonasdottir Aslaug Jonasdottir Asgeir Sigurdsson Arnaldur Gylfason Gisli H Halldorsson Snaedis Kristmundsdottir Gudmundur Thorgeirsson Isleifur Olafsson Hilma Holm Unnur Thorsteinsdottir Patrick Sulem Agnar Helgason Daniel F Gudbjartsson Bjarni V Halldorsson Kari Stefansson

Nat Genet 2017 Apr 27;49(4):588-593. Epub 2017 Feb 27.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.3801DOI Listing
April 2017

Genetic variation at 16q24.2 is associated with small vessel stroke.

Authors:
Matthew Traylor Rainer Malik Mike A Nalls Ioana Cotlarciuc Farid Radmanesh Gudmar Thorleifsson Ken B Hanscombe Carl Langefeld Danish Saleheen Natalia S Rost Idil Yet Tim D Spector Jordana T Bell Eilis Hannon Jonathan Mill Ganesh Chauhan Stephanie Debette Joshua C Bis W T Longstreth M Arfan Ikram Lenore J Launer Sudha Seshadri Monica Anne Hamilton-Bruce Jordi Jimenez-Conde John W Cole Reinhold Schmidt Agnieszka Słowik Robin Lemmens Arne Lindgren Olle Melander Raji P Grewal Ralph L Sacco Tatjana Rundek Kathryn Rexrode Donna K Arnett Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Sara L Pulit Quenna Wong Stephen S Rich Paul I W de Bakker Patrick F McArdle Daniel Woo Christopher D Anderson Huichun Xu Laura Heitsch Myriam Fornage Christina Jern Kari Stefansson Unnur Thorsteinsdottir Solveig Gretarsdottir Cathryn M Lewis Pankaj Sharma Cathie L M Sudlow Peter M Rothwell Giorgio B Boncoraglio Vincent Thijs Chris Levi James F Meschia Jonathan Rosand Steven J Kittner Braxton D Mitchell Martin Dichgans Bradford B Worrall Hugh S Markus

Ann Neurol 2017 Mar;81(3):383-394

Stroke Research Group, Division of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1002/ana.24840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366092PMC
March 2017

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.

Authors:
Dirk Smith Hannes Helgason Patrick Sulem Unnur Steina Bjornsdottir Ai Ching Lim Gardar Sveinbjornsson Haruki Hasegawa Michael Brown Randal R Ketchem Monica Gavala Logan Garrett Adalbjorg Jonasdottir Aslaug Jonasdottir Asgeir Sigurdsson Olafur T Magnusson Gudmundur I Eyjolfsson Isleifur Olafsson Pall Torfi Onundarson Olof Sigurdardottir David Gislason Thorarinn Gislason Bjorn Runar Ludviksson Dora Ludviksdottir H Marike Boezen Andrea Heinzmann Marcus Krueger Celeste Porsbjerg Tarunveer S Ahluwalia Johannes Waage Vibeke Backer Klaus A Deichmann Gerard H Koppelman Klaus Bønnelykke Hans Bisgaard Gisli Masson Unnur Thorsteinsdottir Daniel F Gudbjartsson James A Johnston Ingileif Jonsdottir Kari Stefansson

PLoS Genet 2017 03 8;13(3):e1006659. Epub 2017 Mar 8.

deCODE genetics / Amgen Inc., Reykjavík, Iceland.

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http://dx.doi.org/10.1371/journal.pgen.1006659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362243PMC
March 2017

Rare and low-frequency coding variants alter human adult height.

Authors:
Eirini Marouli Mariaelisa Graff Carolina Medina-Gomez Ken Sin Lo Andrew R Wood Troels R Kjaer Rebecca S Fine Yingchang Lu Claudia Schurmann Heather M Highland Sina Rüeger Gudmar Thorleifsson Anne E Justice David Lamparter Kathleen E Stirrups Valérie Turcot Kristin L Young Thomas W Winkler Tõnu Esko Tugce Karaderi Adam E Locke Nicholas G D Masca Maggie C Y Ng Poorva Mudgal Manuel A Rivas Sailaja Vedantam Anubha Mahajan Xiuqing Guo Goncalo Abecasis Katja K Aben Linda S Adair Dewan S Alam Eva Albrecht Kristine H Allin Matthew Allison Philippe Amouyel Emil V Appel Dominique Arveiler Folkert W Asselbergs Paul L Auer Beverley Balkau Bernhard Banas Lia E Bang Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Heiner Boeing Eric Boerwinkle Carsten A Böger Lori L Bonnycastle Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Amber A Burt Adam S Butterworth David J Carey Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox Gabriel Cuellar-Partida John Danesh Gail Davies Paul I W de Bakker Gert J de Borst Simon de Denus Mark C H de Groot Renée de Mutsert Ian J Deary George Dedoussis Ellen W Demerath Anneke I den Hollander Joe G Dennis Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Alison M Dunning Douglas F Easton Tapani Ebeling Todd L Edwards Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Jessica D Faul Mary F Feitosa Shuang Feng Ele Ferrannini Marco M Ferrario Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Paul W Franks Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Ayush Giri Giorgia Girotto Scott D Gordon Penny Gordon-Larsen Mathias Gorski Niels Grarup Megan L Grove Vilmundur Gudnason Stefan Gustafsson Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Caroline Hayward Liang He Iris M Heid Kauko Heikkilä Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Lynne J Hocking Mette Hollensted Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Carel B Hoyng Paul L Huang Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Min A Jhun Yucheng Jia Xuejuan Jiang Stefan Johansson Marit E Jørgensen Torben Jørgensen Pekka Jousilahti J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Renske Keeman Lambertus A Kiemeney Hidetoshi Kitajima Kirsten B Kluivers Thomas Kocher Pirjo Komulainen Jukka Kontto Jaspal S Kooner Charles Kooperberg Peter Kovacs Jennifer Kriebel Helena Kuivaniemi Sébastien Küry Johanna Kuusisto Martina La Bianca Markku Laakso Timo A Lakka Ethan M Lange Leslie A Lange Carl D Langefeld Claudia Langenberg Eric B Larson I-Te Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Yeheng Liu Yongmei Liu Artitaya Lophatananon Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen David A Mackey Pamela A F Madden Alisa K Manning Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G Martin Angela L Mazul Karina Meidtner Andres Metspalu Paul Mitchell Karen L Mohlke Dennis O Mook-Kanamori Anna Morgan Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Matthias Nauck Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Ioanna Ntalla Jeffrey R O'Connel Heikki Oksa Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Thomas N Person Ailith Pirie Ozren Polasek Danielle Posthuma Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Paul M Ridker John D Rioux Neil Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Kevin Sandow Yadav Sapkota Naveed Sattar Marjanka K Schmidt Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati Shah Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert Vernon Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Valgerdur Steinthorsdottir Heather M Stringham Michael Stumvoll Praveen Surendran Leen M 't Hart Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Sheila Ulivi Sander W van der Laan Andries R Van Der Leij Cornelia M van Duijn Natasja M van Schoor Jessica van Setten Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Diego Vozzi Mark Walker Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Nicholas J Wareham Helen R Warren Jennifer Wessel Sara M Willems James G Wilson Daniel R Witte Michael O Woods Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao He Zheng Wei Zhou Jerome I Rotter Michael Boehnke Sekar Kathiresan Mark I McCarthy Cristen J Willer Kari Stefansson Ingrid B Borecki Dajiang J Liu Kari E North Nancy L Heard-Costa Tune H Pers Cecilia M Lindgren Claus Oxvig Zoltán Kutalik Fernando Rivadeneira Ruth J F Loos Timothy M Frayling Joel N Hirschhorn Panos Deloukas Guillaume Lettre

Nature 2017 02 1;542(7640):186-190. Epub 2017 Feb 1.

Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.

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http://dx.doi.org/10.1038/nature21039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302847PMC
February 2017

A genome-wide association study yields five novel thyroid cancer risk loci.

Authors:
Julius Gudmundsson Gudmar Thorleifsson Jon K Sigurdsson Lilja Stefansdottir Jon G Jonasson Sigurjon A Gudjonsson Daniel F Gudbjartsson Gisli Masson Hrefna Johannsdottir Gisli H Halldorsson Simon N Stacey Hannes Helgason Patrick Sulem Leigha Senter Huiling He Sandya Liyanarachchi Matthew D Ringel Esperanza Aguillo Angeles Panadero Enrique Prats Almudena Garcia-Castaño Ana De Juan Fernando Rivera Li Xu Lambertus A Kiemeney Gudmundur I Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Hoskuldur Kristvinsson Romana T Netea-Maier Thorvaldur Jonsson Jose I Mayordomo Theo S Plantinga Hannes Hjartarson Jon Hrafnkelsson Erich M Sturgis Unnur Thorsteinsdottir Thorunn Rafnar Albert de la Chapelle Kari Stefansson

Nat Commun 2017 02 14;8:14517. Epub 2017 Feb 14.

deCODE genetics/AMGEN, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ncomms14517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316879PMC
February 2017

Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation.

Authors:
Gyda Bjornsdottir Stefania Benonisdottir Gardar Sveinbjornsson Unnur Styrkarsdottir Gudmar Thorleifsson G Bragi Walters Aron Bjornsson Ingvar H Olafsson Elfar Ulfarsson Arnor Vikingsson Ragnheidur Hansdottir Karl O Karlsson Thorunn Rafnar Ingileif Jonsdottir Michael L Frigge Augustine Kong Asmundur Oddsson Gisli Masson Olafur T Magnusson Tomas Gudbjartsson Hreinn Stefansson Patrick Sulem Daniel Gudbjartsson Unnur Thorsteinsdottir Thorgeir E Thorgeirsson Kari Stefansson

Nat Commun 2017 02 22;8:14265. Epub 2017 Feb 22.

deCODE Genetics/Amgen, Inc., Reykjavik IS-101, Iceland.

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http://dx.doi.org/10.1038/ncomms14265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322534PMC
February 2017

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Authors:
Gregory T Jones Gerard Tromp Helena Kuivaniemi Solveig Gretarsdottir Annette F Baas Betti Giusti Ewa Strauss Femke N G Van't Hof Thomas R Webb Robert Erdman Marylyn D Ritchie James R Elmore Anurag Verma Sarah Pendergrass Iftikhar J Kullo Zi Ye Peggy L Peissig Omri Gottesman Shefali S Verma Jennifer Malinowski Laura J Rasmussen-Torvik Kenneth M Borthwick Diane T Smelser David R Crosslin Mariza de Andrade Evan J Ryer Catherine A McCarty Erwin P Böttinger Jennifer A Pacheco Dana C Crawford David S Carrell Glenn S Gerhard David P Franklin David J Carey Victoria L Phillips Michael J A Williams Wenhua Wei Ross Blair Andrew A Hill Thodor M Vasudevan David R Lewis Ian A Thomson Jo Krysa Geraldine B Hill Justin Roake Tony R Merriman Grzegorz Oszkinis Silvia Galora Claudia Saracini Rosanna Abbate Raffaele Pulli Carlo Pratesi Athanasios Saratzis Ana R Verissimo Suzannah Bumpstead Stephen A Badger Rachel E Clough Gillian Cockerill Hany Hafez D Julian A Scott T Simon Futers Simon P R Romaine Katherine Bridge Kathryn J Griffin Marc A Bailey Alberto Smith Matthew M Thompson Frank M van Bockxmeer Stefan E Matthiasson Gudmar Thorleifsson Unnur Thorsteinsdottir Jan D Blankensteijn Joep A W Teijink Cisca Wijmenga Jacqueline de Graaf Lambertus A Kiemeney Jes S Lindholt Anne Hughes Declan T Bradley Kathleen Stirrups Jonathan Golledge Paul E Norman Janet T Powell Steve E Humphries Stephen E Hamby Alison H Goodall Christopher P Nelson Natzi Sakalihasan Audrey Courtois Robert E Ferrell Per Eriksson Lasse Folkersen Anders Franco-Cereceda John D Eicher Andrew D Johnson Christer Betsholtz Arno Ruusalepp Oscar Franzén Eric E Schadt Johan L M Björkegren Leonard Lipovich Anne M Drolet Eric L Verhoeven Clark J Zeebregts Robert H Geelkerken Marc R van Sambeek Steven M van Sterkenburg Jean-Paul de Vries Kari Stefansson John R Thompson Paul I W de Bakker Panos Deloukas Robert D Sayers Seamus C Harrison Andre M van Rij Nilesh J Samani Matthew J Bown

Circ Res 2017 Jan 29;120(2):341-353. Epub 2016 Nov 29.

For the author affiliations, please see the Appendix.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253231PMC
January 2017

Selection against variants in the genome associated with educational attainment.

Authors:
Augustine Kong Michael L Frigge Gudmar Thorleifsson Hreinn Stefansson Alexander I Young Florian Zink Gudrun A Jonsdottir Aysu Okbay Patrick Sulem Gisli Masson Daniel F Gudbjartsson Agnar Helgason Gyda Bjornsdottir Unnur Thorsteinsdottir Kari Stefansson

Proc Natl Acad Sci U S A 2017 01 17;114(5):E727-E732. Epub 2017 Jan 17.

deCODE genetics/Amgen Inc., Reykjavik 101, Iceland;

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http://dx.doi.org/10.1073/pnas.1612113114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293043PMC
January 2017

A sequence variant associating with educational attainment also affects childhood cognition.

Authors:
Bjarni Gunnarsson Guðrún A Jónsdóttir Gyða Björnsdóttir Bettina Konte Patrick Sulem Snædís Kristmundsdóttir Birte Kehr Ómar Gústafsson Hannes Helgason Paul D Iordache Sigurgeir Ólafsson Michael L Frigge Guðmar Þorleifsson Sunna Arnarsdóttir Berglind Stefánsdóttir Ina Giegling Srdjan Djurovic Kjetil S Sundet Thomas Espeseth Ingrid Melle Annette M Hartmann Unnur Thorsteinsdottir Augustine Kong Daníel F Guðbjartsson Ulrich Ettinger Ole A Andreassen Dan Rujescu Jónas G Halldórsson Hreinn Stefánsson Bjarni V Halldórsson Kári Stefánsson

Sci Rep 2016 11 4;6:36189. Epub 2016 Nov 4.

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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http://dx.doi.org/10.1038/srep36189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095652PMC
November 2016

Multi-nucleotide de novo Mutations in Humans.

Authors:
Søren Besenbacher Patrick Sulem Agnar Helgason Hannes Helgason Helgi Kristjansson Aslaug Jonasdottir Adalbjorg Jonasdottir Olafur Th Magnusson Unnur Thorsteinsdottir Gisli Masson Augustine Kong Daniel F Gudbjartsson Kari Stefansson

PLoS Genet 2016 Nov 15;12(11):e1006315. Epub 2016 Nov 15.

deCODE genetics/Amgen, Inc., Iceland.

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http://dx.doi.org/10.1371/journal.pgen.1006315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147774PMC
November 2016

Epigenetic and genetic components of height regulation.

Authors:
Stefania Benonisdottir Asmundur Oddsson Agnar Helgason Ragnar P Kristjansson Gardar Sveinbjornsson Arna Oskarsdottir Gudmar Thorleifsson Olafur B Davidsson Gudny A Arnadottir Gerald Sulem Brynjar O Jensson Hilma Holm Kristjan F Alexandersson Laufey Tryggvadottir G Bragi Walters Sigurjon A Gudjonsson Lucas D Ward Jon K Sigurdsson Paul D Iordache Michael L Frigge Thorunn Rafnar Augustine Kong Gisli Masson Hannes Helgason Unnur Thorsteinsdottir Daniel F Gudbjartsson Patrick Sulem Kari Stefansson

Nat Commun 2016 11 16;7:13490. Epub 2016 Nov 16.

deCODE Genetics/Amgen, Inc., 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ncomms13490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116096PMC
November 2016

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.

Authors:
Janina S Ried Janina Jeff M Audrey Y Chu Jennifer L Bragg-Gresham Jenny van Dongen Jennifer E Huffman Tarunveer S Ahluwalia Gemma Cadby Niina Eklund Joel Eriksson Tõnu Esko Mary F Feitosa Anuj Goel Mathias Gorski Caroline Hayward Nancy L Heard-Costa Anne U Jackson Eero Jokinen Stavroula Kanoni Kati Kristiansson Zoltán Kutalik Jari Lahti Jian'an Luan Reedik Mägi Anubha Mahajan Massimo Mangino Carolina Medina-Gomez Keri L Monda Ilja M Nolte Louis Pérusse Inga Prokopenko Lu Qi Lynda M Rose Erika Salvi Megan T Smith Harold Snieder Alena Stančáková Yun Ju Sung Ioanna Tachmazidou Alexander Teumer Gudmar Thorleifsson Pim van der Harst Ryan W Walker Sophie R Wang Sarah H Wild Sara M Willems Andrew Wong Weihua Zhang Eva Albrecht Alexessander Couto Alves Stephan J L Bakker Cristina Barlassina Traci M Bartz John Beilby Claire Bellis Richard N Bergman Sven Bergmann John Blangero Matthias Blüher Eric Boerwinkle Lori L Bonnycastle Stefan R Bornstein Marcel Bruinenberg Harry Campbell Yii-Der Ida Chen Charleston W K Chiang Peter S Chines Francis S Collins Fracensco Cucca L Adrienne Cupples Francesca D'Avila Eco J C de Geus George Dedoussis Maria Dimitriou Angela Döring Johan G Eriksson Aliki-Eleni Farmaki Martin Farrall Teresa Ferreira Krista Fischer Nita G Forouhi Nele Friedrich Anette Prior Gjesing Nicola Glorioso Mariaelisa Graff Harald Grallert Niels Grarup Jürgen Gräßler Jagvir Grewal Anders Hamsten Marie Neergaard Harder Catharina A Hartman Maija Hassinen Nicholas Hastie Andrew Tym Hattersley Aki S Havulinna Markku Heliövaara Hans Hillege Albert Hofman Oddgeir Holmen Georg Homuth Jouke-Jan Hottenga Jennie Hui Lise Lotte Husemoen Pirro G Hysi Aaron Isaacs Till Ittermann Shapour Jalilzadeh Alan L James Torben Jørgensen Pekka Jousilahti Antti Jula Johanne Marie Justesen Anne E Justice Mika Kähönen Maria Karaleftheri Kay Tee Khaw Sirkka M Keinanen-Kiukaanniemi Leena Kinnunen Paul B Knekt Heikki A Koistinen Ivana Kolcic Ishminder K Kooner Seppo Koskinen Peter Kovacs Theodosios Kyriakou Tomi Laitinen Claudia Langenberg Alexandra M Lewin Peter Lichtner Cecilia M Lindgren Jaana Lindström Allan Linneberg Roberto Lorbeer Mattias Lorentzon Robert Luben Valeriya Lyssenko Satu Männistö Paolo Manunta Irene Mateo Leach Wendy L McArdle Barbara Mcknight Karen L Mohlke Evelin Mihailov Lili Milani Rebecca Mills May E Montasser Andrew P Morris Gabriele Müller Arthur W Musk Narisu Narisu Ken K Ong Ben A Oostra Clive Osmond Aarno Palotie James S Pankow Lavinia Paternoster Brenda W Penninx Irene Pichler Maria G Pilia Ozren Polašek Peter P Pramstaller Olli T Raitakari Tuomo Rankinen D C Rao Nigel W Rayner Rasmus Ribel-Madsen Treva K Rice Marcus Richards Paul M Ridker Fernando Rivadeneira Kathy A Ryan Serena Sanna Mark A Sarzynski Salome Scholtens Robert A Scott Sylvain Sebert Lorraine Southam Thomas Hempel Sparsø Valgerdur Steinthorsdottir Kathleen Stirrups Ronald P Stolk Konstantin Strauch Heather M Stringham Morris A Swertz Amy J Swift Anke Tönjes Emmanouil Tsafantakis Peter J van der Most Jana V Van Vliet-Ostaptchouk Liesbeth Vandenput Erkki Vartiainen Cristina Venturini Niek Verweij Jorma S Viikari Veronique Vitart Marie-Claude Vohl Judith M Vonk Gérard Waeber Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Thomas W Winkler Alan F Wright Laura M Yerges-Armstrong Jing Hua Zhao M Carola Zillikens Dorret I Boomsma Claude Bouchard John C Chambers Daniel I Chasman Daniele Cusi Ron T Gansevoort Christian Gieger Torben Hansen Andrew A Hicks Frank Hu Kristian Hveem Marjo-Riitta Jarvelin Eero Kajantie Jaspal S Kooner Diana Kuh Johanna Kuusisto Markku Laakso Timo A Lakka Terho Lehtimäki Andres Metspalu Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Lyle J Palmer Oluf Pedersen Markus Perola Annette Peters Bruce M Psaty Hannu Puolijoki Rainer Rauramaa Igor Rudan Veikko Salomaa Peter E H Schwarz Alan R Shudiner Jan H Smit Thorkild I A Sørensen Timothy D Spector Kari Stefansson Michael Stumvoll Angelo Tremblay Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Uwe Völker Peter Vollenweider Nicholas J Wareham Hugh Watkins James F Wilson Eleftheria Zeggini Goncalo R Abecasis Michael Boehnke Ingrid B Borecki Panos Deloukas Cornelia M van Duijn Caroline Fox Leif C Groop Iris M Heid David J Hunter Robert C Kaplan Mark I McCarthy Kari E North Jeffrey R O'Connell David Schlessinger Unnur Thorsteinsdottir David P Strachan Timothy Frayling Joel N Hirschhorn Martina Müller-Nurasyid Ruth J F Loos

Nat Commun 2016 11 23;7:13357. Epub 2016 Nov 23.

The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/ncomms13357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114527PMC
November 2016

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:
Aysu Okbay Bart M L Baselmans Jan-Emmanuel De Neve Patrick Turley Michel G Nivard Mark Alan Fontana S Fleur W Meddens Richard Karlsson Linnér Cornelius A Rietveld Jaime Derringer Jacob Gratten James J Lee Jimmy Z Liu Ronald de Vlaming Tarunveer S Ahluwalia Jadwiga Buchwald Alana Cavadino Alexis C Frazier-Wood Nicholas A Furlotte Victoria Garfield Marie Henrike Geisel Juan R Gonzalez Saskia Haitjema Robert Karlsson Sander W van der Laan Karl-Heinz Ladwig Jari Lahti Sven J van der Lee Penelope A Lind Tian Liu Lindsay Matteson Evelin Mihailov Michael B Miller Camelia C Minica Ilja M Nolte Dennis Mook-Kanamori Peter J van der Most Christopher Oldmeadow Yong Qian Olli Raitakari Rajesh Rawal Anu Realo Rico Rueedi Börge Schmidt Albert V Smith Evie Stergiakouli Toshiko Tanaka Kent Taylor Gudmar Thorleifsson Juho Wedenoja Juergen Wellmann Harm-Jan Westra Sara M Willems Wei Zhao Najaf Amin Andrew Bakshi Sven Bergmann Gyda Bjornsdottir Patricia A Boyle Samantha Cherney Simon R Cox Gail Davies Oliver S P Davis Jun Ding Nese Direk Peter Eibich Rebecca T Emeny Ghazaleh Fatemifar Jessica D Faul Luigi Ferrucci Andreas J Forstner Christian Gieger Richa Gupta Tamara B Harris Juliette M Harris Elizabeth G Holliday Jouke-Jan Hottenga Philip L De Jager Marika A Kaakinen Eero Kajantie Ville Karhunen Ivana Kolcic Meena Kumari Lenore J Launer Lude Franke Ruifang Li-Gao David C Liewald Marisa Koini Anu Loukola Pedro Marques-Vidal Grant W Montgomery Miriam A Mosing Lavinia Paternoster Alison Pattie Katja E Petrovic Laura Pulkki-Råback Lydia Quaye Katri Räikkönen Igor Rudan Rodney J Scott Jennifer A Smith Angelina R Sutin Maciej Trzaskowski Anna E Vinkhuyzen Lei Yu Delilah Zabaneh John R Attia David A Bennett Klaus Berger Lars Bertram Dorret I Boomsma Harold Snieder Shun-Chiao Chang Francesco Cucca Ian J Deary Cornelia M van Duijn Johan G Eriksson Ute Bültmann Eco J C de Geus Patrick J F Groenen Vilmundur Gudnason Torben Hansen Catharine A Hartman Claire M A Haworth Caroline Hayward Andrew C Heath David A Hinds Elina Hyppönen William G William Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Liisa Keltikangas-Järvinen Peter Kraft Laura D Kubzansky Terho Lehtimäki Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Melinda Mills Renée de Mutsert Albertine J Oldehinkel Gerard Pasterkamp Nancy L Pedersen Robert Plomin Ozren Polasek Christine Power Stephen S Rich Frits R Rosendaal Hester M den Ruijter David Schlessinger Helena Schmidt Rauli Svento Reinhold Schmidt Behrooz Z Alizadeh Thorkild I A Sørensen Tim D Spector John M Starr Kari Stefansson Andrew Steptoe Antonio Terracciano Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier André G Uitterlinden Peter Vollenweider Gert G Wagner David R Weir Jian Yang Dalton C Conley George Davey Smith Albert Hofman Magnus Johannesson David I Laibson Sarah E Medland Michelle N Meyer Joseph K Pickrell Tõnu Esko Robert F Krueger Jonathan P Beauchamp Philipp D Koellinger Daniel J Benjamin Meike Bartels David Cesarini

Nat Genet 2016 11;48(12):1591

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http://dx.doi.org/10.1038/ng1216-1587bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509058PMC
November 2016