Umadevi Sajjan

Umadevi Sajjan

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Umadevi Sajjan

Umadevi Sajjan

Publications by authors named "Umadevi Sajjan"

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Randomised clinical trial to determine the safety of quercetin supplementation in patients with chronic obstructive pulmonary disease.

BMJ Open Respir Res 2020 Feb;7(1)

Thoracic Medicine and Surgery, Temple University Medical School, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1136/bmjresp-2018-000392DOI Listing
February 2020

Rhinovirus-Induced SIRT-1 via TLR2 Regulates Subsequent Type I and Type III IFN Responses in Airway Epithelial Cells.

J Immunol 2019 Nov 23;203(9):2508-2519. Epub 2019 Sep 23.

Department of Thoracic Surgery and Medicine, Temple University, Philadelphia, PA 19140; and

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http://dx.doi.org/10.4049/jimmunol.1900165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810856PMC
November 2019

Rhinovirus-induces progression of lung disease in a mouse model of COPD via IL-33/ST2 signaling axis.

Clin Sci (Lond) 2019 04 29;133(8):983-996. Epub 2019 Apr 29.

Department of Thoracic Medicine and Surgery, Temple University, Philadelphia, PA, U.S.A.

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http://dx.doi.org/10.1042/CS20181088DOI Listing
April 2019

NOTCH3 contributes to rhinovirus-induced goblet cell hyperplasia in COPD airway epithelial cells.

Thorax 2019 01 10;74(1):18-32. Epub 2018 Jul 10.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2017-210593DOI Listing
January 2019

Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype.

PLoS One 2018 5;13(7):e0199612. Epub 2018 Jul 5.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199612PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033397PMC
December 2018

Bioenergetic Responses to Mycobacterium tuberculosis: A Step Closer to Developing a New Therapy to Treat Tuberculosis in Smokers?

Authors:
Umadevi S Sajjan

Am J Respir Cell Mol Biol 2018 11;59(5):527-528

1 Department of Thoracic Medicine and Surgery Temple University Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1165/rcmb.2018-0225EDDOI Listing
November 2018

Enhancement of Inducible Nitric Oxide Synthase Activity by Low Molecular Weight Peptides Derived from Protamine: A Potential Therapy for Chronic Rhinosinusitis.

Mol Pharm 2015 Jul 2;12(7):2396-405. Epub 2015 Jun 2.

†Department of Chemistry, University of Michigan, 930 North University, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00110DOI Listing
July 2015

Host evasion by Burkholderia cenocepacia.

Front Cell Infect Microbiol 2011 11;1:25. Epub 2012 Jan 11.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.

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http://journal.frontiersin.org/article/10.3389/fcimb.2011.00
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http://dx.doi.org/10.3389/fcimb.2011.00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417383PMC
March 2015

Rhinovirus attenuates non-typeable Hemophilus influenzae-stimulated IL-8 responses via TLR2-dependent degradation of IRAK-1.

PLoS Pathog 2012 4;8(10):e1002969. Epub 2012 Oct 4.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, United States of America.

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https://dx.plos.org/10.1371/journal.ppat.1002969
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http://dx.doi.org/10.1371/journal.ppat.1002969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464227PMC
April 2013

Rhinovirus-induced barrier dysfunction in polarized airway epithelial cells is mediated by NADPH oxidase 1.

J Virol 2011 Jul 20;85(13):6795-808. Epub 2011 Apr 20.

Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 W. Medical Center Dr., Room 3570, MSRBII, Box 5688, Ann Arbor, MI 48109-0688, USA.

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http://dx.doi.org/10.1128/JVI.02074-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126521PMC
July 2011

MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.

PLoS Pathog 2011 May 26;7(5):e1002070. Epub 2011 May 26.

Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102730PMC
May 2011

Elastase- and LPS-exposed mice display altered responses to rhinovirus infection.

Am J Physiol Lung Cell Mol Physiol 2009 Nov 11;297(5):L931-44. Epub 2009 Sep 11.

Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 W. Medical Center Dr., Rm. 3570, MSRBII, Box 5688, Ann Arbor, MI 48109-5688, USA.

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http://www.physiology.org/doi/10.1152/ajplung.00150.2009
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http://dx.doi.org/10.1152/ajplung.00150.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777490PMC
November 2009

Azithromycin increases survival and reduces lung inflammation in cystic fibrosis mice.

Inflamm Res 2009 Aug 7;58(8):491-501. Epub 2009 Mar 7.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48105, USA.

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http://link.springer.com/10.1007/s00011-009-0015-9
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http://dx.doi.org/10.1007/s00011-009-0015-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164971PMC
August 2009

Rhinovirus disrupts the barrier function of polarized airway epithelial cells.

Am J Respir Crit Care Med 2008 Dec 11;178(12):1271-81. Epub 2008 Sep 11.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109-0688, USA.

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http://dx.doi.org/10.1164/rccm.200801-136OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599868PMC
December 2008

A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.

Infect Immun 2008 Dec 29;76(12):5447-55. Epub 2008 Sep 29.

Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://iai.asm.org/cgi/doi/10.1128/IAI.00451-08
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http://dx.doi.org/10.1128/IAI.00451-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583573PMC
December 2008

Burkholderia cenocepacia ET12 strain activates TNFR1 signalling in cystic fibrosis airway epithelial cells.

Cell Microbiol 2008 Jan 14;10(1):188-201. Epub 2007 Aug 14.

Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, 1150 W. Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://doi.wiley.com/10.1111/j.1462-5822.2007.01029.x
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http://dx.doi.org/10.1111/j.1462-5822.2007.01029.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226749PMC
January 2008

Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression.

Am J Physiol Lung Cell Mol Physiol 2007 Oct 13;293(4):L1021-8. Epub 2007 Jul 13.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan 48109-0688, USA.

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http://dx.doi.org/10.1152/ajplung.00060.2007DOI Listing
October 2007

Lung cells from neonates show a mesenchymal stem cell phenotype.

Am J Respir Crit Care Med 2007 Jun 1;175(11):1158-64. Epub 2007 Mar 1.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1164/rccm.200607-941OCDOI Listing
June 2007

Quercetin blocks airway epithelial cell chemokine expression.

Am J Respir Cell Mol Biol 2006 Nov 22;35(5):602-10. Epub 2006 Jun 22.

University of Michigan, 1150 W. Medical Center Drive, Box 0688, Ann Arbor, MI 48109-0688, USA.

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http://dx.doi.org/10.1165/rcmb.2006-0149OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643278PMC
November 2006

H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM-1 and TLR3 expression.

FASEB J 2006 Oct 16;20(12):2121-3. Epub 2006 Aug 16.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1096/fj.06-5806fjeDOI Listing
October 2006

Intracellular trafficking and replication of Burkholderia cenocepacia in human cystic fibrosis airway epithelial cells.

Cell Microbiol 2006 Sep;8(9):1456-66

Department of Pediatrics and Communicable Disease, University of Michigan Medical School, Ann Arbor, 48109, USA.

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http://doi.wiley.com/10.1111/j.1462-5822.2006.00724.x
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http://dx.doi.org/10.1111/j.1462-5822.2006.00724.xDOI Listing
September 2006

Absence of typical unfolded protein response in primary cultured cystic fibrosis airway epithelial cells.

Biochem Biophys Res Commun 2006 Apr 3;343(1):135-43. Epub 2006 Mar 3.

Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109-0688, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0600450
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http://dx.doi.org/10.1016/j.bbrc.2006.02.137DOI Listing
April 2006

Disruption of tight junctions during traversal of the respiratory epithelium by Burkholderia cenocepacia.

Infect Immun 2005 Nov;73(11):7107-12

Department of Pediatrics, University of Michigan Medical School, 1150 W. Medical Center Dr., 8323 MSRB III, Box 0646, Ann Arbor, MI 48109-0646, USA.

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http://dx.doi.org/10.1128/IAI.73.11.7107-7112.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1273860PMC
November 2005

Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia.

Proc Natl Acad Sci U S A 2003 Dec 12;100(26):15364-9. Epub 2003 Dec 12.

Programme in Lung Biology Research and Canadian Institutes of Health Research Group in Lung Development, Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.

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http://dx.doi.org/10.1073/pnas.2436478100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC307573PMC
December 2003

Effect of chondroitinase ABC on purulent sputum from cystic fibrosis and other patients.

Pediatr Res 2003 Apr 15;53(4):619-27. Epub 2003 Jan 15.

Research Institute, Department of Structural Biology and Biochemistry, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1203/01.PDR.0000054780.11755.B9DOI Listing
April 2003

Identification and molecular analysis of cable pilus biosynthesis genes in Burkholderia cepacia.

Microbiology 2003 Apr;149(Pt 4):961-971

Division of Structural Biology and Biochemistry, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.1099/mic.0.26176-0DOI Listing
April 2003

Lack of cable pili expression by cblA-containing Burkholderia cepacia complex.

Microbiology 2002 Nov;148(Pt 11):3477-3484

Department of Pediatrics and Communicable Diseases, University of Michigan, 8323 MSRB III, Box 0646, 1150 W. Medical Center Drive, Ann Arbor, MI 48109, USA2.

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http://mic.microbiologyresearch.org/content/journal/micro/10
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http://dx.doi.org/10.1099/00221287-148-11-3477DOI Listing
November 2002

Interaction of cblA/adhesin-positive Burkholderia cepacia with squamous epithelium.

Cell Microbiol 2002 Feb;4(2):73-86

Departments of Structural Biology and Biochemistry, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1046/j.1462-5822.2002.00171.xDOI Listing
February 2002