Ulrike Protzer

Ulrike Protzer

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Ulrike Protzer

Ulrike Protzer

Publications by authors named "Ulrike Protzer"

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A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control.

J Hepatol 2020 Jan 15. Epub 2020 Jan 15.

Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany; Institute of Virology, Technical University of Munich and Helmholtz Zentrum München, Schneckenburgerstrasse 8, 81675 Munich, Germany; Institute of Molecular Immunology and Experimental Oncology, Technical University of Munich, Ismaningerstraße 22, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.12.019DOI Listing
January 2020

Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-titer HBV Carrier Mice.

Gastroenterology 2020 Jan 28. Epub 2020 Jan 28.

Institute of Virology, Technical University of Munich / Helmholtz Zentrum München, Trogerstrasse 30, D-81675 Munich, Germany; German Center for Infection Research (DZIF), Munich, Heidelberg and Hannover/Braunschweig partner sites, Germany. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.01.032DOI Listing
January 2020

A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection.

Antimicrob Agents Chemother 2019 12 20;64(1). Epub 2019 Dec 20.

Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany

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http://dx.doi.org/10.1128/AAC.01440-19DOI Listing
December 2019

A PCR assay to quantify patterns of HBV transcription.

J Gen Virol 2019 Dec 17. Epub 2019 Dec 17.

Nuffield Department of Medicine, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford, UK.

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http://dx.doi.org/10.1099/jgv.0.001373DOI Listing
December 2019

Revisiting Hepatitis B Virus: Challenges of Curative Therapies.

J Virol 2019 Oct 30;93(20). Epub 2019 Sep 30.

Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, California, USA

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http://dx.doi.org/10.1128/JVI.01032-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798116PMC
October 2019

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.

Braz J Microbiol 2019 Oct 26. Epub 2019 Oct 26.

Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany.

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http://dx.doi.org/10.1007/s42770-019-00176-1DOI Listing
October 2019

Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention.

Cancer Cell 2019 Sep;36(3):250-267.e9

Institute of Virology, Technical University of Munich, 81675 Munich, Germany; Helmholtz Center Munich, 85764 Neuherberg, Germany; Institute of Molecular Immunology and Experimental Oncology, Technical University of Munich, Ismaningerstraße 22, 81675 Munich, Germany; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 242, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.08.001DOI Listing
September 2019

Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems.

Virol J 2019 08 9;16(1):100. Epub 2019 Aug 9.

Institute of Virology, Faculty of Medicine, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1186/s12985-019-1212-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688233PMC
August 2019

Evaluation of a Fully Human, Hepatitis B Virus-Specific Chimeric Antigen Receptor in an Immunocompetent Mouse Model.

Mol Ther 2019 05 10;27(5):947-959. Epub 2019 Feb 10.

Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, 81675 Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, 81675 Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016193004
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http://dx.doi.org/10.1016/j.ymthe.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520494PMC
May 2019

Targeting Innate and Adaptive Immune Responses to Cure Chronic HBV Infection.

Gastroenterology 2019 01 24;156(2):325-337. Epub 2018 Oct 24.

Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183516
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http://dx.doi.org/10.1053/j.gastro.2018.10.032DOI Listing
January 2019

PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice.

Antiviral Res 2019 01 12;161:134-143. Epub 2018 Nov 12.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675, Munich, Germany; German Center for Infection Research (DZIF), Munich Partner Site, 81675, Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542183045
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http://dx.doi.org/10.1016/j.antiviral.2018.11.003DOI Listing
January 2019

Towards curative therapy of chronic viral hepatitis.

Z Gastroenterol 2019 Jan 14;57(1):61-73. Epub 2019 Jan 14.

Institut für Virologie, Technische Universität München.

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http://dx.doi.org/10.1055/a-0824-1576DOI Listing
January 2019

Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes.

Hepatology 2018 12 27;68(6):2089-2105. Epub 2018 Sep 27.

Institute of Molecular Immunology and Experimental Oncology, Klinikum Rechts der Isar, Technical University of Munich, Germany.

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http://dx.doi.org/10.1002/hep.30080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585666PMC
December 2018

Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels.

J Hepatol 2018 12 22;69(6):1231-1241. Epub 2018 Aug 22.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; Technische Universität München, Institute for Advanced Study, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.08.012DOI Listing
December 2018

The Global Hepatitis B Virus Genotype Distribution Approximated from Available Genotyping Data.

Genes (Basel) 2018 Oct 15;9(10). Epub 2018 Oct 15.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstrasse 30, D-81675 München, Germany.

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http://www.mdpi.com/2073-4425/9/10/495
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http://dx.doi.org/10.3390/genes9100495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210291PMC
October 2018

The hepatitis B epidemic and the urgent need for cure preparedness.

Nat Rev Gastroenterol Hepatol 2018 09;15(9):517-518

WHO Collaborating Centre for Viral Hepatitis, Doherty Institute, Melbourne, Australia.

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http://dx.doi.org/10.1038/s41575-018-0041-6DOI Listing
September 2018

One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors.

Mol Ther Nucleic Acids 2018 Sep 7;12:242-253. Epub 2018 Jun 7.

Center of Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023846PMC
September 2018

Overcoming immune tolerance in chronic hepatitis B by therapeutic vaccination.

Curr Opin Virol 2018 06 8;30:58-67. Epub 2018 May 8.

Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Trogerstrasse 30, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2018.04.003DOI Listing
June 2018

Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle.

Antiviral Res 2018 03 5;151:4-7. Epub 2018 Jan 5.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstrasse 30, 81675 Munich, Germany; German Center for Infection Research (DZIF), Munich site, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2018.01.001DOI Listing
March 2018

Analyses of HBV cccDNA Quantification and Modification.

Methods Mol Biol 2017 ;1540:59-72

Institute of Virology, Technische Universität München/Helmholtz Zentrum, Munich, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6700-1_6DOI Listing
January 2018

Viral hepatitis and liver cancer.

Philos Trans R Soc Lond B Biol Sci 2017 10;372(1732)

Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Trogerstrasse 30, 81675 Muenchen, Germany

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http://dx.doi.org/10.1098/rstb.2016.0274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597741PMC
October 2017

IFN-α-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection.

Sci Rep 2017 10 5;7(1):12715. Epub 2017 Oct 5.

Department and Institute of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

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http://dx.doi.org/10.1038/s41598-017-13082-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629255PMC
October 2017

Visualizing HEV infection in human liver tissue.

Authors:
Ulrike Protzer

J Hepatol 2017 09 24;67(3):443-445. Epub 2017 Jun 24.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstr. 30, 81675 München, Germany; German Center for Infection Research, Munich Partner Site, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.06.016DOI Listing
September 2017

PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation.

Hepatology 2017 08 19;66(2):398-415. Epub 2017 Jun 19.

Key Laboratory of Medical Molecular Virology, Ministry of Education and Health, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/hep.29133DOI Listing
August 2017

Applicability of Metal Nanoparticles in the Detection and Monitoring of Hepatitis B Virus Infection.

Viruses 2017 07 21;9(7). Epub 2017 Jul 21.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München-German Center for Environmental Health, Trogerstr. 30, 81675 Munich, Germany.

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http://dx.doi.org/10.3390/v9070193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537685PMC
July 2017

Viral hepatitis: The bumpy road to animal models for HBV infection.

Authors:
Ulrike Protzer

Nat Rev Gastroenterol Hepatol 2017 06 12;14(6):327-328. Epub 2017 Apr 12.

Institute of Virology, Technische Universität München and Helmholtz Zentrum München, Trogerstrasse 30, 81675 Munich, Germany.

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http://dx.doi.org/10.1038/nrgastro.2017.44DOI Listing
June 2017

Novel viral and host targets to cure hepatitis B.

Curr Opin Virol 2017 06 20;24:38-45. Epub 2017 Apr 20.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstrasse 30, 81675 Munich, Germany; German Center for Infection Research (DZIF), Munich Partner Site, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2017.03.019DOI Listing
June 2017

Immune Reconstitution After HCV Clearance With Direct Antiviral Agents: Potential Consequences for Patients With HCC?

Transplantation 2017 05;101(5):904-909

1 Department of Surgery, University Hospital Regensburg, Regensburg, Germany. 2 Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany, German Center for Infection Research (DZIF), Munich, Germany.

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http://dx.doi.org/10.1097/TP.0000000000001606DOI Listing
May 2017

Secreted Interferon-Inducible Factors Restrict Hepatitis B and C Virus Entry In Vitro.

J Immunol Res 2017 6;2017:4828936. Epub 2017 Mar 6.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675 Munich, Germany; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.

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http://dx.doi.org/10.1155/2017/4828936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358466PMC
May 2017

Therapeutic vaccination for chronic hepatitis B.

Curr Opin Virol 2017 04 25;23:75-81. Epub 2017 Apr 25.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection research (DZIF), Munich Partner Site, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2017.03.011DOI Listing
April 2017

Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions.

J Hepatol 2017 03 14;66(3):494-503. Epub 2016 Oct 14.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316493PMC
March 2017

Control of Hepatitis B Virus by Cytokines.

Viruses 2017 01 20;9(1). Epub 2017 Jan 20.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich 81675, Germany.

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http://dx.doi.org/10.3390/v9010018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294987PMC
January 2017

Serious outbreak of human metapneumovirus in patients with hematologic malignancies.

Leuk Lymphoma 2016 30;57(3):623-7. Epub 2015 Jun 30.

a III. Medical Department, Technische Universität München , Munich , Germany.

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http://dx.doi.org/10.3109/10428194.2015.1067699DOI Listing
December 2016

Entecavir allows an unexpectedly high residual replication of HBV mutants resistant to lamivudine.

Antivir Ther 2015 5;20(8):779-87. Epub 2015 Jan 5.

Institute of Medical Virology, Justus Liebig University Giessen, National Reference Center for Hepatitis B and D Viruses, Biomedical Research Center Seltersberg, Giessen, Germany.

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http://dx.doi.org/10.3851/IMP2928DOI Listing
November 2016

"To Be or Not to Be": Immune Tolerance in Chronic Hepatitis B.

Gastroenterology 2016 11 1;151(5):805-806. Epub 2016 Oct 1.

Institute of Molecular Immunology and Experimental Oncology, University Hospital München rechts der Isar, Technische Universität München and German Center for Infection Research (DZIF), Munich site, München, Germany.

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http://dx.doi.org/10.1053/j.gastro.2016.09.038DOI Listing
November 2016

Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA.

EMBO Mol Med 2016 09 1;8(9):1082-98. Epub 2016 Sep 1.

Department of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, Heidelberg University Hospital, Heidelberg, Germany BioQuant, University of Heidelberg, Heidelberg, Germany

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http://dx.doi.org/10.15252/emmm.201506172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009812PMC
September 2016

Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring.

J Transl Med 2016 06 14;14(1):175. Epub 2016 Jun 14.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Schneckenburgerstr. 8, 81675, Munich, Germany.

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http://dx.doi.org/10.1186/s12967-016-0932-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906590PMC
June 2016

Herpes simplex virus in bronchoalveolar lavage fluid of medical intensive care unit patients: Association with lung injury and outcome.

J Crit Care 2016 Apr 8;32:138-44. Epub 2015 Dec 8.

II. Medizinische Klinik und Poliklinik. Klinikum rechts der Isar der Technischen Universität München, 81675 München, Germany.

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http://dx.doi.org/10.1016/j.jcrc.2015.11.019DOI Listing
April 2016

Attacking hepatitis B virus cccDNA--The holy grail to hepatitis B cure.

J Hepatol 2016 Apr;64(1 Suppl):S41-S48

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstrasse 30, 81675 Munich, Germany; German Center for Infection Research (DZIF), Munich Site, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.02.009DOI Listing
April 2016

Protein-prime/modified vaccinia virus Ankara vector-boost vaccination overcomes tolerance in high-antigenemic HBV-transgenic mice.

Vaccine 2016 Feb 15;34(7):923-32. Epub 2016 Jan 15.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany; German Center for Infection Research (DZIF), Munich Site, 81675 Munich, Germany; Clinical Cooperation Group Antigen Specific Immunotherapy and Immune Monitoring, Helmholtz Zentrum München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.12.060DOI Listing
February 2016

Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis.

Gastroenterology 2016 Jan 28;150(1):194-205. Epub 2015 Sep 28.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research, Munich and Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.09.026DOI Listing
January 2016

T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice.

Gastroenterology 2015 Oct 5;149(4):1042-52. Epub 2015 Jun 5.

Institute of Virology, Technische Universität München, Helmholtz Zentrum München, München, Germany; German Center for Infection Research (DZIF), Munich Site, Germany; Clinical Cooperation Groups Antigen Specific Immunotherapy and Immune Monitoring, Technische Universität München, Helmholtz Zentrum München, München, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085150078
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http://dx.doi.org/10.1053/j.gastro.2015.05.055DOI Listing
October 2015

Hepatitis: Epigenetic control of HBV by HBx protein--releasing the break?

Authors:
Ulrike Protzer

Nat Rev Gastroenterol Hepatol 2015 Oct 1;12(10):558-9. Epub 2015 Sep 1.

Institute of Virology, Technische Universität München and the Helmholtz Zentrum München, Trogerstrasse 30, D-81675 München, Germany.

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http://dx.doi.org/10.1038/nrgastro.2015.152DOI Listing
October 2015

Oncogenic potential of hepatitis B virus encoded proteins.

Curr Opin Virol 2015 Oct 29;14:109-15. Epub 2015 Sep 29.

Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2015.08.015DOI Listing
October 2015

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

Cell 2015 Apr 16;161(3):486-500. Epub 2015 Apr 16.

Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy; Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.03.005DOI Listing
April 2015

Mouse models for therapeutic vaccination against hepatitis B virus.

Med Microbiol Immunol 2015 Feb 19;204(1):95-102. Epub 2014 Dec 19.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstr. 30, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00430-014-0378-6DOI Listing
February 2015

The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets.

J Pathol 2015 Jan;235(2):355-67

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; Second Medical Department, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; German Centre for Infection research (DZIF), Munich Partner Site, Germany.

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http://dx.doi.org/10.1002/path.4434DOI Listing
January 2015

[Specific degradation of nuclear hepatitis B virus covalently closed circular DNA].

Med Sci (Paris) 2014 Aug-Sep;30(8-9):724-6. Epub 2014 Sep 1.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Allemagne - German Center for Infection Research (DZIF), Allemagne.

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http://dx.doi.org/10.1051/medsci/20143008003DOI Listing
November 2014

New pharmacological strategies to fight enveloped viruses.

Trends Pharmacol Sci 2014 Sep 6;35(9):470-8. Epub 2014 Aug 6.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstrasse 30, 81675 Munich, Germany; German Center for Infection Research (DZIF), Munich site, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2014.06.004DOI Listing
September 2014

Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo.

Hepatology 2014 Jun 30;59(6):2110-20. Epub 2014 Apr 30.

Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany; German Center for Infection Research, Partner sites Bonn-Cologne and Munich, Germany; Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/hep.26990DOI Listing
June 2014

Virology. Response to Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA".

Science 2014 Jun;344(6189):1237

Institute of Virology, Technische Universität München, Helmholtz Zentrum München, Munich, Germany.

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http://dx.doi.org/10.1126/science.1254083DOI Listing
June 2014

HCV-induced immune responses influence the development of operational tolerance after liver transplantation in humans.

Sci Transl Med 2014 Jun;6(242):242ra81

Liver Unit, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of Barcelona, Barcelona 08036, Spain. Institute of Liver Studies, MRC Centre for Transplantation, King's College London, London SE5 9RS, UK.

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http://dx.doi.org/10.1126/scitranslmed.3008793DOI Listing
June 2014

LINE(1)s of evidence in HBV-driven liver cancer.

Cell Host Microbe 2014 Mar;15(3):249-50

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2014.02.015DOI Listing
March 2014

Direct effects of hepatitis B virus-encoded proteins and chronic infection in liver cancer development.

Dig Dis 2013 17;31(1):138-51. Epub 2013 Jun 17.

Institute of Virology, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1159/000347209DOI Listing
October 2013

New norovirus classified as a recombinant GII.g/GII.1 causes an extended foodborne outbreak at a university hospital in Munich.

J Clin Virol 2013 Sep 9;58(1):24-30. Epub 2013 Jul 9.

Institute of Virology, Technische Universität München and Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.

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http://dx.doi.org/10.1016/j.jcv.2013.06.018DOI Listing
September 2013

Ezetimibe blocks hepatitis B virus infection after virus uptake into hepatocytes.

Antiviral Res 2013 Feb 21;97(2):195-7. Epub 2012 Dec 21.

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.

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http://dx.doi.org/10.1016/j.antiviral.2012.12.008DOI Listing
February 2013

Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment.

BMC Microbiol 2012 Dec 28;12:307. Epub 2012 Dec 28.

Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.

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http://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-
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http://dx.doi.org/10.1186/1471-2180-12-307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549285PMC
December 2012

Longitudinal changes in HIV-1-specific T-cell quality associated with viral load dynamic.

J Clin Virol 2012 Oct 13;55(2):114-20. Epub 2012 Jul 13.

Institute of Virology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.jcv.2012.06.017DOI Listing
October 2012

Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.

Hepatology 2012 Sep 8;56(3):873-83. Epub 2012 Aug 8.

Institutes of Virology, Immunology, and Hygiene, Technische Universität München / Helmholtz Zentrum München, München, Germany.

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http://doi.wiley.com/10.1002/hep.25765
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September 2012

Immune tolerance against HBV can be overcome in HBV transgenic mice by immunization with dendritic cells pulsed by HBVsvp.

Vaccine 2012 Sep 3;30(42):6034-9. Epub 2012 Aug 3.

Department of Gastroenterology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2012.07.057DOI Listing
September 2012