Ulrike Luderer

Ulrike Luderer

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Ulrike Luderer

Ulrike Luderer

Publications by authors named "Ulrike Luderer"

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In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses That Deplete Ovarian Follicles in Mice.

Environ Mol Mutagen 2019 Jun 21;60(5):410-420. Epub 2018 Dec 21.

Environmental Health Science and Research Bureau, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1002/em.22261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615722PMC
June 2019

Glutathione deficiency sensitizes cultured embryonic mouse ovaries to benzo[a]pyrene-induced germ cell apoptosis.

Toxicol Appl Pharmacol 2018 08 22;352:38-45. Epub 2018 May 22.

Department of Medicine, University of California Irvine, Irvine, CA 92617, United States; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92617, United States; Program in Public Health, University of California Irvine, Irvine, CA 92617, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0041008X183023
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http://dx.doi.org/10.1016/j.taap.2018.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013410PMC
August 2018

Very low doses of heavy oxygen ion radiation induce premature ovarian failure.

Reproduction 2017 Aug 20;154(2):123-133. Epub 2017 May 20.

Department of MedicineUniversity of California Irvine, Irvine, California, USA

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http://dx.doi.org/10.1530/REP-17-0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598766PMC
August 2017

Ovarian effects of prenatal exposure to benzo[a]pyrene: Roles of embryonic and maternal glutathione status.

Reprod Toxicol 2017 04 6;69:187-195. Epub 2017 Mar 6.

U.S. Food, Drug Administration, Division of Genetic, Reproductive Toxicology, National Center for Toxicological Research, Jefferson, AR, United States.

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http://dx.doi.org/10.1016/j.reprotox.2017.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422106PMC
April 2017

Associations between urinary biomarkers of polycyclic aromatic hydrocarbon exposure and reproductive function during menstrual cycles in women.

Environ Int 2017 Mar 5;100:110-120. Epub 2017 Jan 5.

Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, 4676 Columbia Parkway, Cincinnati, OH 45226, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2016.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291797PMC
March 2017

Spatial Characterization of Bioenergetics and Metabolism of Primordial to Preovulatory Follicles in Whole Ex Vivo Murine Ovary.

Biol Reprod 2016 12 28;95(6):129. Epub 2016 Sep 28.

Department of Developmental and Cell Biology, University of California Irvine, Irvine, California

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http://dx.doi.org/10.1095/biolreprod.116.142141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315427PMC
December 2016

The Mouse Fetal Ovary Has Greater Sensitivity Than the Fetal Testis to Benzo[a]pyrene-Induced Germ Cell Death.

Toxicol Sci 2016 08 13;152(2):372-81. Epub 2016 May 13.

*Departments of Medicine Developmental and Cell Biology Program in Public Health, University of California, Irvine 92617

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http://dx.doi.org/10.1093/toxsci/kfw083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960906PMC
August 2016

Charged iron particles, components of space radiation, destroy ovarian follicles.

Hum Reprod 2016 08 31;31(8):1816-26. Epub 2016 May 31.

Department of Medicine, University of California Irvine, Irvine, CA 92617, USA Developmental and Cell Biology, University of California Irvine, Irvine, CA 92617, USA Program in Public Health, University of California Irvine, Irvine, CA 92617, USA

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https://academic.oup.com/humrep/article-lookup/doi/10.1093/h
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http://dx.doi.org/10.1093/humrep/dew126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974665PMC
August 2016

Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice.

Reprod Toxicol 2015 Dec 3;58:24-32. Epub 2015 Aug 3.

Department of Medicine, University of California Irvine, USA; Department of Developmental and Cell Biology, University of California Irvine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2015.07.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690751PMC
December 2015

Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian Failure.

Endocrinology 2015 Sep 17;156(9):3329-43. Epub 2015 Jun 17.

Departments of Medicine (J.L., B.N.N., U.L.) and Developmental and Cell Biology (U.L.), University of California Irvine, Irvine, California 92617; and Department of Environmental and Occupational Health Sciences (I.M., T.J.K.), University of Washington, Seattle, Washington 98195.

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http://dx.doi.org/10.1210/en.2015-1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541624PMC
September 2015

Reprint of "In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective".

Toxicol Lett 2014 Oct 28;230(2):314-21. Epub 2013 Nov 28.

Center for Occupational and Environmental Health, Department of Medicine, 100 Theory Drive, Suite 100, University of California Irvine, Irvine, CA 92617, USA; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92697-2300, USA; Program in Public Health, University of California Irvine, Irvine, CA 92697-3957, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2013.11.017DOI Listing
October 2014

Ovarian toxicity from reactive oxygen species.

Authors:
Ulrike Luderer

Vitam Horm 2014 ;94:99-127

Medicine, Developmental and Cell Biology, and Public Health, University of California Irvine, Irvine, California, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/B97801280009530
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http://dx.doi.org/10.1016/B978-0-12-800095-3.00004-3DOI Listing
August 2014

In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective.

Toxicol Lett 2013 Nov 6;223(2):260-7. Epub 2013 Oct 6.

Center for Occupational and Environmental Health, Department of Medicine, 100 Theory Drive, Suite 100, University of California Irvine, Irvine, CA 92617, USA.

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http://dx.doi.org/10.1016/j.toxlet.2013.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856224PMC
November 2013

Effects of gestational and lactational exposure to heptachlor epoxide on age at puberty and reproductive function in men and women.

Environ Res 2013 Feb 26;121:84-94. Epub 2012 Nov 26.

Center for Occupational and Environmental Health and Division of Occupational and Environmental Medicine, Department of Medicine, University of California Irvine, 100 Theory, Suite 100, Irvine, CA 92617, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001393511200313
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http://dx.doi.org/10.1016/j.envres.2012.11.001DOI Listing
February 2013

Roles of reactive oxygen species and antioxidants in ovarian toxicity.

Biol Reprod 2012 Feb 9;86(2):27. Epub 2012 Feb 9.

Novartis Institute for BioMedical Research, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1095/biolreprod.111.095224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290661PMC
February 2012

Oxidative damage increases and antioxidant gene expression decreases with aging in the mouse ovary.

Biol Reprod 2011 Apr 8;84(4):775-82. Epub 2010 Dec 8.

Department of Medicine, University of California, Irvine, CA, USA.

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http://dx.doi.org/10.1095/biolreprod.110.088583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062040PMC
April 2011

Follicle-stimulating hormone and estradiol interact to stimulate glutathione synthesis in rat ovarian follicles and granulosa cells.

Biol Reprod 2009 Oct 10;81(4):636-46. Epub 2009 Jun 10.

Departments of Medicine and Developmental and Cell Biology, University of California Irvine, Irvine, California, USA.

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http://dx.doi.org/10.1095/biolreprod.109.078378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754881PMC
October 2009

Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death.

Mutagenesis 2009 May 18;24(3):211-24. Epub 2009 Jan 18.

Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92617, USA.

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http://dx.doi.org/10.1093/mutage/gen073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674984PMC
May 2009

Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse.

J Biol Chem 2009 Feb 3;284(6):3488-95. Epub 2008 Dec 3.

Division of Endocrinology, Veterans Affairs Medical Center, Long Beach, California 90822, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M806249200
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http://dx.doi.org/10.1074/jbc.M806249200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635032PMC
February 2009

Induction of apoptosis by 9,10-dimethyl-1,2-benzanthracene in cultured preovulatory rat follicles is preceded by a rise in reactive oxygen species and is prevented by glutathione.

Biol Reprod 2007 Sep 6;77(3):442-51. Epub 2007 Jun 6.

Department of Community and Environmental Medicine, University of California Irvine, Irvine, California 92617, USA.

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http://dx.doi.org/10.1095/biolreprod.107.060368DOI Listing
September 2007

Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion.

Toxicol Sci 2007 Jul 13;98(1):216-30. Epub 2007 Apr 13.

Department of Community and Environmental Medicine, University of California, Irvine, California 92617, USA.

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http://dx.doi.org/10.1093/toxsci/kfm087DOI Listing
July 2007

Opposing effects of glutathione depletion and follicle-stimulating hormone on reactive oxygen species and apoptosis in cultured preovulatory rat follicles.

Endocrinology 2006 Mar 8;147(3):1224-36. Epub 2005 Dec 8.

Center for Occupational and Environmental Health, University of California Irvine, 5201 California Avenue, Suite 100, Irvine, California 92617, USA.

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http://dx.doi.org/10.1210/en.2005-1281DOI Listing
March 2006

Minimal ovarian upregulation of glutamate cysteine ligase expression in response to suppression of glutathione by buthionine sulfoximine.

Reprod Toxicol 2006 Feb 23;21(2):186-96. Epub 2005 Sep 23.

Division of Occupational and Environmental Medicine, Department of Medicine, University of California at Irvine, 5201 California Avenue, Suite 100, 92617, USA.

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http://dx.doi.org/10.1016/j.reprotox.2005.07.011DOI Listing
February 2006

Gonadotropin regulation of glutamate cysteine ligase catalytic and modifier subunit expression in rat ovary is subunit and follicle stage specific.

Am J Physiol Endocrinol Metab 2005 Sep 5;289(3):E391-402. Epub 2005 Apr 5.

Department of Community and Environmental Medicine, University of California at Irvine, Irvine, California 92617, USA.

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http://dx.doi.org/10.1152/ajpendo.00531.2004DOI Listing
September 2005

Effects of occupational solvent exposure on reproductive hormone concentrations and fecundability in men.

Am J Ind Med 2004 Dec;46(6):614-26

Division of Occupational and Environmental Medicine, Department of Medicine, University of California, Irvine, California 92617, USA.

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http://dx.doi.org/10.1002/ajim.20100DOI Listing
December 2004

Effects of cyclophosphamide and buthionine sulfoximine on ovarian glutathione and apoptosis.

Free Radic Biol Med 2004 Jun;36(11):1366-77

Division of Occupational and Environmental Medicine, Department of Medicine, University of California at Irvine, Irvine, CA 92612, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490400185
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http://dx.doi.org/10.1016/j.freeradbiomed.2004.02.067DOI Listing
June 2004

Gestational and lactational exposure to heptachlor does not alter reproductive system development in rats.

Vet Hum Toxicol 2004 Jun;46(3):113-8

Division of Laboratory Animal Medicine, University of California Los Angeles, Los Angeles, CA, USA.

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June 2004

Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis.

Mol Reprod Dev 2003 Jul;65(3):254-61

Department of Medicine, Division of Occupational and Environmental Medicine, University of California, Irvine, California 96212, USA.

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http://dx.doi.org/10.1002/mrd.10298DOI Listing
July 2003