Ulrike Köhl

Ulrike Köhl

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Ulrike Köhl

Ulrike Köhl

Publications by authors named "Ulrike Köhl"

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Editorial: Tailoring NK Cell Receptor-Ligand Interactions: An Art in Evolution.

Front Immunol 2018 27;9:351. Epub 2018 Feb 27.

Department of Medical Oncology, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar.

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http://dx.doi.org/10.3389/fimmu.2018.00351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835124PMC
March 2019

CAR-Expressing Natural Killer Cells for Cancer Retargeting.

Transfus Med Hemother 2019 Feb 5;46(1):4-13. Epub 2019 Feb 5.

Fraunhofer Institute for Cell Therapy and Immunology (IZI), Leipzig, Germany.

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http://dx.doi.org/10.1159/000495771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558329PMC
February 2019

High-dose vitamin D in Addison's disease regulates T-cells and monocytes: A pilot trial.

Nutrition 2018 05 2;49:66-73. Epub 2017 Dec 2.

Department of Internal Medicine I, Division of Endocrinology, Diabetes and Metabolism, University Hospital, Goethe University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.nut.2017.10.021DOI Listing
May 2018

Possible Impact of Cytomegalovirus-Specific CD8 T Cells on Immune Reconstitution and Conversion to Complete Donor Chimerism after Allogeneic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2017 Jul 23;23(7):1046-1053. Epub 2017 Mar 23.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.03.027DOI Listing
July 2017

Natural Killer Cell-Based Cancer Immunotherapies: From Immune Evasion to Promising Targeted Cellular Therapies.

Front Immunol 2017 12;8:745. Epub 2017 Jul 12.

Institute of Cellular Therapeutics, IFB-Tx, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.3389/fimmu.2017.00745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506076PMC
July 2017

Generation and flow cytometric quality control of clinical-scale TCRαβ/CD19-depleted grafts.

Cytometry B Clin Cytom 2017 03 14;92(2):126-135. Epub 2015 Dec 14.

Clinic for Pediatric and Adolescent Medicine, University Hospital, Frankfurt, Germany.

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http://doi.wiley.com/10.1002/cyto.b.21328
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http://dx.doi.org/10.1002/cyto.b.21328DOI Listing
March 2017

Specific phenotype and function of CD56-expressing innate immune cell subsets in human thymus.

J Leukoc Biol 2016 12 28;100(6):1297-1310. Epub 2016 Jun 28.

Department of Internal Medicine 5, Hematology and Oncology, Friedrich-Alexander Universität Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany;

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http://dx.doi.org/10.1189/jlb.1A0116-038RDOI Listing
December 2016

Optimization of individualized graft composition: CD3/CD19 depletion combined with CD34 selection for haploidentical transplantation.

Transfusion 2016 09 27;56(9):2336-45. Epub 2016 Jun 27.

Clinic for Pediatric and Adolescent Medicine, University Hospital, Frankfurt, Germany.

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http://dx.doi.org/10.1111/trf.13694DOI Listing
September 2016

Efficient generation of gene-modified human natural killer cells via alpharetroviral vectors.

J Mol Med (Berl) 2016 Jan 25;94(1):83-93. Epub 2015 Aug 25.

Institute of Experimental Hematology, Hannover Medical School, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00109-015-1327-6DOI Listing
January 2016

Advantages and applications of CAR-expressing natural killer cells.

Front Pharmacol 2015 12;6:21. Epub 2015 Feb 12.

Institute of Cellular Therapeutics Integrated Research and Treatment Center Transplantation, Hannover Medical School Hannover, Germany.

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http://dx.doi.org/10.3389/fphar.2015.00021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325659PMC
March 2015

5-lipoxygenase is a direct target of miR-19a-3p and miR-125b-5p.

J Immunol 2015 Feb 14;194(4):1646-53. Epub 2015 Jan 14.

Institute of Pharmaceutical Chemistry, Goethe University, 60438 Frankfurt/Main, Germany;

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http://dx.doi.org/10.4049/jimmunol.1402163DOI Listing
February 2015

Interleukin-2-stimulated natural killer cells are less susceptible to mycophenolate mofetil than non-activated NK cells: possible consequences for immunotherapy.

Cancer Immunol Immunother 2014 Aug 8;63(8):821-33. Epub 2014 May 8.

Clinic for Pediatric and Adolescent Medicine, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany,

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http://dx.doi.org/10.1007/s00262-014-1556-5DOI Listing
August 2014

Regulation of advanced therapy medicinal products in Europe and the role of academia.

Cytotherapy 2014 Mar 8;16(3):289-97. Epub 2013 Oct 8.

Department of Haematology, Royal Free Hospital & University College London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2013.08.003DOI Listing
March 2014

Multimer monitoring of CMV-specific T cells in research and in clinical applications.

Diagn Microbiol Infect Dis 2014 Mar 15;78(3):201-12. Epub 2013 Nov 15.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany; Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover, Germany; German Centre for Infection Research (DZIF), Partnerside Hannover-Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.diagmicrobio.2013.11.007DOI Listing
March 2014

Natural ligands and antibody-based fusion proteins: harnessing the immune system against cancer.

Trends Mol Med 2014 Feb 19;20(2):72-82. Epub 2013 Nov 19.

University of Cologne, Clinic 1 for Internal Medicine, 50924 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2013.10.006DOI Listing
February 2014

Treatment of patients with advanced cancer with the natural killer cell line NK-92.

Cytotherapy 2013 Dec 1;15(12):1563-70. Epub 2013 Oct 1.

Institute for Transfusion Medicine and Immunohematology, Goethe University Hospital, Frankfurt am Main, Germany; German Red Cross Blood Donation Service, Baden-Württemberg-Hessen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2013.06.017DOI Listing
December 2013

Immunosenescence-associated microRNAs in age and heart failure.

Eur J Heart Fail 2013 Apr 20;15(4):385-93. Epub 2012 Dec 20.

Institute for Cardiovascular Regeneration, Center of Molecular Medicine, Theodor Stern Kai 7, D-60590 Frankfurt, Germany.

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http://dx.doi.org/10.1093/eurjhf/hfs184DOI Listing
April 2013

Natural killer cells and antifungal host response.

Clin Vaccine Immunol 2013 Apr 30;20(4):452-8. Epub 2013 Jan 30.

Pediatric Hematology and Oncology, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://cvi.asm.org/content/20/4/452.full.pdf
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http://cvi.asm.org/cgi/doi/10.1128/CVI.00606-12
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http://dx.doi.org/10.1128/CVI.00606-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623417PMC
April 2013

Immunotherapy against invasive fungal diseases in stem cell transplant recipients.

Immunol Invest 2011 31;40(7-8):839-52. Epub 2011 May 31.

Pediatric Hematology and Oncology, Children's Hospital III, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.3109/08820139.2011.581732DOI Listing
February 2012

The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells.

Cytotherapy 2012 Jan 6;14(1):91-103. Epub 2011 Oct 6.

University Children's Hospital of Frankfurt/Main and Department of Pediatric Hematology, Oncology and Hemostaseology, Goethe-University Frankfurt/Main, Frankfurt/Main, Germany.

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http://dx.doi.org/10.3109/14653249.2011.613931DOI Listing
January 2012

Mechanisms of tumor and viral immune escape from natural killer cell-mediated surveillance.

J Innate Immun 2011 11;3(4):344-54. Epub 2011 May 11.

Institute of Biomedical Research, Georg-Speyer-Haus, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1159/000327014DOI Listing
October 2011

Rapid immune recovery and low TRM in haploidentical stem cell transplantation in children and adolescence using CD3/CD19-depleted stem cells.

Best Pract Res Clin Haematol 2011 Sep 25;24(3):331-7. Epub 2011 Jun 25.

Hospital for Children and Adolescents II/III, University Hospital Frankfurt, Theodor Stern Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.beha.2011.04.005DOI Listing
September 2011

Mesenchymal stromal cells for treatment of steroid-refractory GvHD: a review of the literature and two pediatric cases.

Int Arch Med 2011 Aug 15;4(1):27. Epub 2011 Aug 15.

Children's Cancer Research and Roman Herzog Comprehensive Cancer Center, Department of Pediatrics, Klinikum rechts der Isar, Technische Universität München, Kölner Platz 1, 80804 Munich, Germany.

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http://dx.doi.org/10.1186/1755-7682-4-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169455PMC
August 2011

Adoptive antifungal T cell immunotherapy--into the clinic?

Med Mycol 2011 Apr 30;49 Suppl 1:S164-9. Epub 2010 Jun 30.

Pediatric Hematology and Oncology, Children's Hospital III, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.3109/13693786.2010.497953DOI Listing
April 2011

Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia.

J Infect Dis 2011 Feb 14;203(3):430-5. Epub 2010 Dec 14.

Pediatric Hematology and Oncology, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1093/infdis/jiq062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071101PMC
February 2011

IL-2-activated haploidentical NK cells restore NKG2D-mediated NK-cell cytotoxicity in neuroblastoma patients by scavenging of plasma MICA.

Eur J Immunol 2010 Nov 27;40(11):3255-67. Epub 2010 Oct 27.

Pediatric Hematology and Oncology Laboratory for Stem Cell Transplantation and Immunotherapy, Hospital of Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1002/eji.201040568DOI Listing
November 2010

Challenges and prospects of adoptive immunotherapy in prevention and treatment of opportunistic mycoses in hematologic transplant recipients.

Curr Infect Dis Rep 2010 Nov;12(6):444-9

Pediatric Hematology and Oncology, Children´s Hospital III, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://link.springer.com/10.1007/s11908-010-0130-3
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http://dx.doi.org/10.1007/s11908-010-0130-3DOI Listing
November 2010

Impaired pneumococcal immunity in children after treatment for acute lymphoblastic leukaemia.

Br J Haematol 2009 Dec 18;147(5):700-5. Epub 2009 Sep 18.

Paediatric Haematology and Oncology, University of Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07903.xDOI Listing
December 2009

Cultivated anti-Aspergillus T(H)1 cells.

Med Mycol 2009 10;47 Suppl 1:S170-4. Epub 2008 Jun 10.

Pediatric Hematology and Oncology, Children's Hospital III, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1080/13693780802169120DOI Listing
July 2009

Cytotoxic effects of treosulfan and busulfan against leukemic cells of pediatric patients.

Cancer Chemother Pharmacol 2008 Oct 2;62(5):821-30. Epub 2008 Feb 2.

Pediatric Hematology and Oncology, University Hospital, 60596, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00280-007-0669-3DOI Listing
October 2008

Enumeration of functionally active anti-Aspergillus T-cells in human peripheral blood.

J Immunol Methods 2008 Jun 20;335(1-2):41-5. Epub 2008 Mar 20.

Pediatric Hematology and Oncology, Children's Hospital III, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.jim.2008.02.014DOI Listing
June 2008

Activation of Epac stimulates integrin-dependent homing of progenitor cells.

Blood 2008 Mar 21;111(5):2640-6. Epub 2007 Nov 21.

Molecular Cardiology, Department of Internal Medicine III, J. W. Goethe University of Frankfurt, Theodor Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.1182/blood-2007-04-086231DOI Listing
March 2008

A novel five-colour flow cytometric assay to determine NK cell cytotoxicity against neuroblastoma and other adherent tumour cells.

J Immunol Methods 2007 Aug 16;325(1-2):140-7. Epub 2007 Jul 16.

Paediatric Haematology and Oncology of Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.jim.2007.06.013DOI Listing
August 2007

Natural-killer-cell-based treatment in haematopoietic stem-cell transplantation.

Best Pract Res Clin Haematol 2006 ;19(4):811-24

Service d'Hématologie, Departement Medecine Interne, Hôpitaux Universitaires de Genève, Genève, Switzerland.

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http://dx.doi.org/10.1016/j.beha.2006.06.004DOI Listing
December 2006

Fatal neonatal-onset mitochondrial respiratory chain disease with T cell immunodeficiency.

Pediatr Res 2006 Sep 20;60(3):321-6. Epub 2006 Jul 20.

Department of General Paediatrics, JW Goethe University Frankfurt, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1203/01.pdr.0000233252.60457.cfDOI Listing
September 2006

Generation of highly purified and functionally active human TH1 cells against Aspergillus fumigatus.

Blood 2006 Mar 1;107(6):2562-9. Epub 2005 Dec 1.

Pediatric Hematology and Oncology, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany.

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http://dx.doi.org/10.1182/blood-2005-04-1660DOI Listing
March 2006

IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):261-6

University Hospital Frankfurt, Paediatric Haematology and Oncology, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.bcmd.2004.08.013DOI Listing
April 2005

Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia.

Pathol Biol (Paris) 2005 Apr;53(3):159-61

Klinik für Kinderheilkunde III (Pediatric Hematology, Oncology and Haemostaselogy), Theodor Stern Kai 7, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.patbio.2004.03.010DOI Listing
April 2005

A novel four-colour flow cytometric assay to determine natural killer cell or T-cell-mediated cellular cytotoxicity against leukaemic cells in peripheral or bone marrow specimens containing greater than 20% of normal cells.

J Immunol Methods 2005 Jan 19;296(1-2):63-76. Epub 2004 Dec 19.

Laboratory for Stem Cell Transplantation and Immunotherapy, Paediatric Haematology, Oncology and Haemostaseology, Johann Wolfgang Goethe-Universität, Theodor-Stern-Kai 7, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.jim.2004.10.014DOI Listing
January 2005