Ulrik Lassen

Ulrik Lassen

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Ulrik Lassen

Ulrik Lassen

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Combining PARP inhibition with PD-1 inhibitors.

Authors:
Ulrik Lassen

Lancet Oncol 2019 Sep 1;20(9):1196-1198. Epub 2019 Aug 1.

Department of Oncology, Rigshospitalet, 2100 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30509-1DOI Listing
September 2019

Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein.

Cells 2019 Aug 28;8(9). Epub 2019 Aug 28.

Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.3390/cells8090998DOI Listing
August 2019

Outcome of Bevacizumab Therapy in Patients with Recurrent Glioblastoma Treated with Angiotensin System Inhibitors.

Cancer Invest 2018 ;36(9-10):512-519

a Department of Radiation Biology, Department of Oncology , The Finsen Center , Rigshospitalet, Copenhagen , Denmark.

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http://dx.doi.org/10.1080/07357907.2018.1544639DOI Listing
February 2019

Extracranial metastases in glioblastoma-Two case stories.

Clin Case Rep 2019 Feb 27;7(2):289-294. Epub 2018 Dec 27.

Department of Oncology Rigshospitalet Copenhagen Denmark.

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http://dx.doi.org/10.1002/ccr3.1980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389476PMC
February 2019

TRK Inhibition: A New Tumor-Agnostic Treatment Strategy.

Target Oncol 2018 10;13(5):545-556

Department of Oncology, Rigshospitalet, DK-2100, Copenhagen Ø, Denmark.

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http://dx.doi.org/10.1007/s11523-018-0590-1DOI Listing
October 2018

Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival.

J Neurooncol 2018 May 5;137(3):533-542. Epub 2018 Jan 5.

Department of Radiation Biology, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s11060-017-2739-7DOI Listing
May 2018

Patient information in phase 1 trials: A systematic review.

Psychooncology 2018 03 26;27(3):768-780. Epub 2017 Oct 26.

Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/pon.4559DOI Listing
March 2018

A systematic review of targeted agents for non-small cell lung cancer.

Acta Oncol 2018 Feb 25;57(2):176-186. Epub 2017 Nov 25.

b Department of Oncology , Rigshospitalet , Copenhagen , Denmark.

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https://www.tandfonline.com/doi/full/10.1080/0284186X.2017.1
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http://dx.doi.org/10.1080/0284186X.2017.1404634DOI Listing
February 2018

Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.

Cancer Invest 2018 Feb 2;36(2):165-174. Epub 2018 Feb 2.

a Department of Radiation Biology , The Finsen Center, Rigshospitalet , Copenhagen , Denmark.

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http://dx.doi.org/10.1080/07357907.2018.1430818DOI Listing
February 2018

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

N Engl J Med 2018 02;378(8):731-739

From Memorial Sloan Kettering Cancer Center (A. Drilon, J.F.H., R.B., M.L., D.M.H.) and Weill Cornell Medical College (A. Drilon, D.M.H.), New York; University of Texas Southwestern Medical Center-Children's Health, Dallas (T.W.L.); Stanford Cancer Center, Stanford University, Palo Alto (S.K.), Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California (L.M.), and UCLA David Geffen School of Medicine (N.F.), Los Angeles, and Loxo Oncology, South San Francisco (B.B.T., K.E., S.C., N.C.K., M.C.C.) - all in California; Dana-Farber-Boston Children's Cancer and Blood Disorders Center (S.G.D.), Dana-Farber Cancer Institute (G.D.D., M.N.), Ludwig Center at Harvard (G.D.D.), and Massachusetts General Hospital (A.F.F.) - all in Boston; the Finsen Center, Rigshospitalet, Copenhagen (U.N.L.); University of Colorado, Aurora (R.C.D.); St. Jude Children's Research Hospital, Memphis (A.S.P.), and Vanderbilt University, Nashville (J.B.) - both in Tennessee; Cincinnati Children's Hospital Medical Center, Cincinnati (B.T.); University Hospitals of Cleveland Medical Center (A. Dowlati) and Taussig Cancer Institute, Cleveland Clinic (D.P.S.S.), Cleveland; University of Pennsylvania Perelman School of Medicine, Department of Otorhinolaryngology and Head and Neck Surgery, and the Abramson Cancer Center (M.S.B.), and Fox Chase Cancer Center (W.S.E.-D.), Philadelphia; University of Washington-Seattle Cancer Care Alliance (C.B.), Seattle Children's Hospital (E.R.R.), and Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center (D.S. Hawkins), Seattle; University of Texas M.D. Anderson Cancer Center, Houston (F.M.-B., D.S. Hong); Inova Schar Cancer Institute, Falls Church, VA (J.D.); START Madrid, Centro Integral Oncológico Clara Campal, Madrid (V.B.); Nemours Children's Hospital, Orlando (R.N.), and Memorial Cancer Institute-Florida International University, Miami (L.E.R.) - both in Florida; Oregon Health and Science University, Portland (M.T.); and WVU Cancer Institute, West Virginia University, Morgantown (P.C.M.).

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http://dx.doi.org/10.1056/NEJMoa1714448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857389PMC
February 2018

Detection of copy number alterations in cell-free tumor DNA from plasma.

BBA Clin 2017 Jun 4;7:120-126. Epub 2017 Apr 4.

Center for Genomic Medicine, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark.

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http://dx.doi.org/10.1016/j.bbacli.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390666PMC
June 2017

Clinical trial allocation in multinational pharmaceutical companies - a qualitative study on influential factors.

Pharmacol Res Perspect 2017 06 19;5(3):e00317. Epub 2017 May 19.

Department of Dermatology Copenhagen University Hospital Bispebjerg Bispebjerg Bakke 23, entrance 9DK-2400 Copenhagen NV Denmark.

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http://dx.doi.org/10.1002/prp2.317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464345PMC
June 2017

Hallmarks of glioblastoma: a systematic review.

ESMO Open 2016 22;1(6):e000144. Epub 2017 Feb 22.

Department of Radiation Biology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1136/esmoopen-2016-000144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419216PMC
February 2017

First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors.

J Clin Oncol 2016 12 31;34(34):4142-4150. Epub 2016 Oct 31.

Albiruni R. Abdul Razak and Lee-Anne Stayner, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Morten Mau-Soerensen and Ulrik Lassen, Rigshospitalet, Copenhagen, Denmark; Nashat Y. Gabrail, Gabrail Cancer Institute, Canton, OH; John F. Gerecitano, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College, New York, NY; Anthony F. Shields, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Thaddeus J. Unger, Jean R. Saint-Martin, Robert Carlson, Yosef Landesman, Dilara McCauley, Tami Rashal, Mansoor R. Mirza, Michael Kauffman, and Sharon Shacham, Karyopharm Therapeutics, Newton, MA; and Richard Kim and Amit Mahipal, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

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http://dx.doi.org/10.1200/JCO.2015.65.3949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562433PMC
December 2016

Effect of bevacizumab on intracranial meningiomas in patients with neurofibromatosis type 2 - a retrospective case series.

Int J Neurosci 2016 Nov 6;126(11):1002-6. Epub 2015 Oct 6.

d Department of Oncology and Radiotherapy , Copenhagen University Hospital , Copenhagen , Denmark.

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http://dx.doi.org/10.3109/00207454.2015.1092443DOI Listing
November 2016

Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients.

Mol Oncol 2016 10 26;10(8):1160-8. Epub 2016 May 26.

Department of Radiation Biology, The Finsen Center, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark; Department of Oncology, The Finsen Center, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark; Phase I Unit, Finsencenter, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.molonc.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423207PMC
October 2016

Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma.

Nucl Med Biol 2016 Mar 22;43(3):198-205. Epub 2015 Dec 22.

Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.nucmedbio.2015.12.002DOI Listing
March 2016

Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma.

J Nucl Med 2016 Feb 1;57(2):272-8. Epub 2015 Oct 1.

Department of Clinical Physiology, Nuclear Medicine, and PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark

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http://jnm.snmjournals.org/content/57/2/272.full.pdf
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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.115.161703
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http://dx.doi.org/10.2967/jnumed.115.161703DOI Listing
February 2016

The effect of bevacizumab on vestibular schwannoma tumour size and hearing in patients with neurofibromatosis type 2.

Eur Arch Otorhinolaryngol 2015 Dec 25;272(12):3627-33. Epub 2014 Nov 25.

Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00405-014-3398-3DOI Listing
December 2015

The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts.

PLoS One 2014 11;9(2):e100009. Epub 2014 Jun 11.

Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100009PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053391PMC
October 2015

Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma.

N Engl J Med 2015 Sep 26;373(13):1207-19. Epub 2015 Aug 26.

From the Department of Hematology, University Medical Center Utrecht, Utrecht (H.M.L., M.C.M., N.W.C.J.D.), and the Department of Hematology, VU University Medical Center, Amsterdam (H.M.L., N.W.C.J.D.) - both in the Netherlands; Vejle Hospital and University of Southern Denmark, Vejle (T.P., J.K.), and Rigshospitalet and University of Copenhagen (P.G., U.L.) and Genmab (N.L., S.L., L.B., N.B.), Copenhagen - all in Denmark; Dana-Farber Cancer Institute, Harvard Medical School, Boston (J.P.L., P.G.R.); Karolinska Institute and the Department of Medicine, Division of Hematology, Karolinska University Hospital at Huddinge, Stockholm (H.N.), and Skåne University Hospital and Lund University, Lund (M.H.) - all in Sweden; Myeloma Unit, Division of Hematology, University of Turin, Turin, Italy (A.P.); Janssen Research and Development, Spring House, PA (T.A., C.M.U., A.K.S.); and Janssen Research and Development, Raritan, NJ (I.K., J.W.).

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http://dx.doi.org/10.1056/NEJMoa1506348DOI Listing
September 2015

Phase 1 dose-escalation study of the antiplacental growth factor monoclonal antibody RO5323441 combined with bevacizumab in patients with recurrent glioblastoma.

Neuro Oncol 2015 Jul 9;17(7):1007-15. Epub 2015 Feb 9.

Department of Oncology, Rigshospitalet, Copenhagen, Denmark (U.L., M.M.-S.); Department of Radiology, Rigshospitalet, Copenhagen, Denmark (V.A.L.); Aix-Marseille University A.P.-H.M., Department of Neuro-Oncology, University Hospital Timone, Marseille, France (O.L.C., M.B.); Department of Clinical Oncology, The Christie Hospital N.H.S Foundation Trust, Manchester, England (C.M.); Department of Neurology, University Hospital Zurich, Zurich, Switzerland (P.R., M.W.); Roche Diagnostics GmbH, Penzberg, Germany (O.K., K.H., A.L.); Hoffmann La Roche Pharmaceuticals, Nutley, NewJersey (K.W.); F. Hoffmann-La Roche Ltd, Basel, Switzerland (J.T.).

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http://dx.doi.org/10.1093/neuonc/nov019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654352PMC
July 2015

A phase I trial of intravenous catumaxomab: a bispecific monoclonal antibody targeting EpCAM and the T cell coreceptor CD3.

Cancer Chemother Pharmacol 2015 May 27;75(5):1065-73. Epub 2015 Mar 27.

Department of Oncology, The Finsen Centre, Rigshospitalet, Copenhagen, Denmark,

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http://dx.doi.org/10.1007/s00280-015-2728-5DOI Listing
May 2015

[The genome and cancer treatment].

Ugeskr Laeger 2014 Nov;176(46)

Klinisk Biokemi, Righospitalet, Blegdamsvej 9, 2100 København Ø.

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November 2014

The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients.

Cancer Manag Res 2014 26;6:373-87. Epub 2014 Sep 26.

Department of Radiation Biology, Copenhagen University Hospital, Copenhagen, Denmark ; Department of Oncology, Copenhagen University Hospital, Copenhagen, Denmark ; Phase I Unit, The Finsencenter, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.2147/CMAR.S39306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186574PMC
October 2014

Personalized oncology: genomic screening in phase 1.

APMIS 2014 Aug;122(8):723-33

Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/apm.12293DOI Listing
August 2014

Sorafenib in advanced hepatocellular carcinoma: a nationwide retrospective study of efficacy and tolerability.

ScientificWorldJournal 2013 29;2013:931972. Epub 2013 Jan 29.

Department of Oncology, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus, Denmark.

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https://www.hindawi.com/journals/tswj/2013/931972/
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http://dx.doi.org/10.1155/2013/931972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569916PMC
September 2013

Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme.

Anticancer Res 2013 Apr;33(4):1657-60

Department of Oncology, Rigshospitalet, Copenhagen, Denmark.

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April 2013

The optimality of different strategies for supplemental staging of non-small-cell lung cancer: a health economic decision analysis.

Value Health 2013 Jan-Feb;16(1):57-65

Centre for Health Services Research and Technology Assessment, Institute for Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1016/j.jval.2012.09.007DOI Listing
March 2013

Phase II open-label study of nintedanib in patients with recurrent glioblastoma multiforme.

J Neurooncol 2013 Jan 27;111(2):205-12. Epub 2012 Nov 27.

Department of Oncology 5073, Section for Neuro-oncology and Phase I Unit, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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http://link.springer.com/10.1007/s11060-012-1009-y
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http://dx.doi.org/10.1007/s11060-012-1009-yDOI Listing
January 2013

A phase I study of concurrent chemoradiotherapy and cetuximab for locally advanced esophageal cancer.

Anticancer Res 2012 Sep;32(9):4019-23

Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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September 2012

Phase II activity of belinostat (PXD-101), carboplatin, and paclitaxel in women with previously treated ovarian cancer.

Int J Gynecol Cancer 2012 Jul;22(6):979-86

Program in Women's Oncology, Women & Infants' Hospital/Alpert Medical School of Brown University, Providence, RI 02905, USA.

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http://dx.doi.org/10.1097/IGC.0b013e31825736fdDOI Listing
July 2012

Phase II trial of erlotinib and bevacizumab in patients with advanced upper gastrointestinal cancers.

Acta Oncol 2012 Feb 21;51(2):234-42. Epub 2011 Oct 21.

Department of Oncology, The Finsen Centre, Copenhagen University Hospital Rigshospitalet, Denmark.

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http://dx.doi.org/10.3109/0284186X.2011.619568DOI Listing
February 2012

Preoperative staging of lung cancer with PET/CT: cost-effectiveness evaluation alongside a randomized controlled trial.

Eur J Nucl Med Mol Imaging 2011 May 6;38(5):802-9. Epub 2011 Jan 6.

Centre for Health Service Research and Technology Assessment, University of Southern Denmark, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00259-010-1703-yDOI Listing
May 2011

A Phase I-II dose escalation study of fixed-dose rate gemcitabine, oxaliplatin and capecitabine every two weeks in advanced cholangiocarcinomas.

Acta Oncol 2011 Apr 29;50(3):448-54. Epub 2010 Jul 29.

Department of Oncology, The Finsen Centre, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.3109/0284186X.2010.500300DOI Listing
April 2011

Biomarkers in tissue from patients with upper gastrointestinal cancers treated with erlotinib and bevacizumab.

Cancer Biol Ther 2011 Apr 15;11(8):732-9. Epub 2011 Apr 15.

Department of Oncology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.4161/cbt.11.8.14889DOI Listing
April 2011

Irinotecan and bevacizumab in recurrent glioblastoma multiforme.

Expert Opin Pharmacother 2011 Apr 9;12(5):825-33. Epub 2011 Mar 9.

Copenhagen University Hospital, The Finsencenter, Department of Oncology, Blegdamsvej 9, DK 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1517/14656566.2011.566558DOI Listing
April 2011

PET-CT in preoperative staging of lung cancer.

N Engl J Med 2011 Mar;364(10):980-1

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http://dx.doi.org/10.1056/NEJMc1012974DOI Listing
March 2011

Cetuximab insufficiently inhibits glioma cell growth due to persistent EGFR downstream signaling.

Cancer Invest 2010 Oct;28(8):775-87

Department of Radiation Biology, The Finsen Center, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.3109/07357907.2010.483506DOI Listing
October 2010

PET/CT imaging in response evaluation of patients with small cell lung cancer.

Lung Cancer 2006 Oct 17;54(1):41-9. Epub 2006 Aug 17.

Department of Nuclear Medicine and PET, Centre of Diagnostic Imaging, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.lungcan.2006.06.012DOI Listing
October 2006

Natriuretic peptides in the monitoring of anthracycline induced reduction in left ventricular ejection fraction.

Eur J Heart Fail 2005 Jan;7(1):87-93

Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen Ø, Denmark.

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http://dx.doi.org/10.1016/j.ejheart.2004.03.009DOI Listing
January 2005

FDG-PET imaging in small cell lung cancer: any value?

Authors:
Ulrik Lassen

Lung Cancer 2002 Jul;37(1)

Department of Medical Oncology, Hillerød Hospital, DK-3400, Hillerød, Denmark.

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http://dx.doi.org/10.1016/s0169-5002(02)00019-3DOI Listing
July 2002