Ulrich Steidl

Ulrich Steidl

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Ulrich Steidl

Publications by authors named "Ulrich Steidl"

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Targeting Immunophenotypic Markers on Leukemic Stem Cells: How Lessons from Current Approaches and Advances in the Leukemia Stem Cell (LSC) Model Can Inform Better Strategies for Treating Acute Myeloid Leukemia (AML).

Cold Spring Harb Perspect Med 2020 Jan 2;10(1). Epub 2020 Jan 2.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1101/cshperspect.a036251DOI Listing
January 2020

Mechanisms and therapeutic prospects of thrombopoietin receptor agonists.

Semin Hematol 2019 10 19;56(4):262-278. Epub 2019 Oct 19.

Albert Einstein College of Medicine, New York, NY. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2019.09.001DOI Listing
October 2019

Runx1 promotes murine erythroid progenitor proliferation and inhibits differentiation by preventing Pu.1 downregulation.

Proc Natl Acad Sci U S A 2019 09 20;116(36):17841-17847. Epub 2019 Aug 20.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461;

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http://dx.doi.org/10.1073/pnas.1901122116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731665PMC
September 2019

Aurora Kinase A Inhibition: A Mega-Hit for Myelofibrosis Therapy?

Clin Cancer Res 2019 Aug 13;25(16):4868-4870. Epub 2019 Jun 13.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697558PMC
August 2019

Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells.

Exp Hematol 2019 05 13;73:38-49.e7. Epub 2019 Apr 13.

Department of Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2019.03.003DOI Listing
May 2019

Inhibition of HIF1α Signaling: A Grand Slam for MDS Therapy?

Cancer Discov 2018 11;8(11):1355-1357

Department of Cell Biology, and Department of Medicine (Oncology), Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-18-1061DOI Listing
November 2018

STAT3 inhibition as a therapeutic strategy for leukemia.

Leuk Lymphoma 2018 09 22;59(9):2068-2074. Epub 2017 Nov 22.

a Division of Hematologic Malignancies, Department of Oncology, Albert Einstein College of Medicine , Bronx , NY , USA.

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http://dx.doi.org/10.1080/10428194.2017.1397668DOI Listing
September 2018

Linking histone methylation, transcription rates, and stem cell robustness.

Haematologica 2018 07;103(7):1093

Department of Cell Biology, Albert Einstein College of Medicine - Montefiore Medical Center, Bronx, NY, USA.

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http://dx.doi.org/10.3324/haematol.2018.196089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029540PMC
July 2018

Metabolic strugGLS after FLT3 inhibition in AML.

Blood 2018 04;131(15):1631-1632

Albert Einstein College of Medicine.

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http://dx.doi.org/10.1182/blood-2018-03-836338DOI Listing
April 2018

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.

Cancer Cell 2017 10;32(4):490-505.e10

Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793879PMC
October 2017

Stem and progenitor cell alterations in myelodysplastic syndromes.

Blood 2017 03 3;129(12):1586-1594. Epub 2017 Feb 3.

Division of Hemato-Oncology, Department of Oncology, Albert Einstein College of Medicine, Bronx, NY; and.

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http://dx.doi.org/10.1182/blood-2016-10-696062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364336PMC
March 2017

ETO2-GLIS2: A Chimeric Transcription Factor Drives Leukemogenesis through a Neomorphic Transcription Network.

Cancer Cell 2017 03;31(3):307-308

Department of Cell Biology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA; Ruth L. and David S. Gottesman Institute for Stem Cell Research and Regenerative Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.02.015DOI Listing
March 2017

DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic Disorders.

Front Oncol 2016 22;6:187. Epub 2016 Aug 22.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA; Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA; Einstein Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.3389/fonc.2016.00187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992944PMC
September 2016

Eliminating Cancer Stem Cells in CML with Combination Transcriptional Therapy.

Cell Stem Cell 2016 07;19(1):6-8

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine (Oncology), Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, NY 10467, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Institute for Stem Cell Research and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.06.005DOI Listing
July 2016

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

Nat Cell Biol 2016 06 25;18(6):607-18. Epub 2016 Apr 25.

The Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Medicine, Division of Hematology/Oncology, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ncb3346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884136PMC
June 2016

Molecular Mechanism of Mutant CALR-Mediated Transformation.

Cancer Discov 2016 Apr;6(4):344-6

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York. Department of Medicine, Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, New York. Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, New York. Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832981PMC
April 2016

Ectopic DNMT3B expression delays leukemogenesis.

Blood 2016 Mar;127(12):1525-6

ALBERT EINSTEIN COLLEGE OF MEDICINE.

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http://dx.doi.org/10.1182/blood-2016-01-692137DOI Listing
March 2016

PAK1 is a therapeutic target in acute myeloid leukemia and myelodysplastic syndrome.

Blood 2015 Aug 13;126(9):1118-27. Epub 2015 Jul 13.

Departments of Cell Biology and of Medicine, Division of Hemato-Oncology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY;

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http://dx.doi.org/10.1182/blood-2014-12-618801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551362PMC
August 2015

Functionally relevant RNA helicase mutations in familial and sporadic myeloid malignancies.

Cancer Cell 2015 May;27(5):609-11

Department of Cell Biology and Department of Medicine (Oncology), Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.04.013DOI Listing
May 2015

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.

Cancer Cell 2015 Apr;27(4):502-15

Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518555PMC
April 2015

A synthetic lethal approach targeting mutant isocitrate dehydrogenase in acute myeloid leukemia.

Nat Med 2015 Feb;21(2):113-4

Department of Cell Biology; the Department of Medicine (Oncology), Division of Hemato-Oncology; the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research; and the Albert Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3796DOI Listing
February 2015

CDK6, a new target in MLL-driven leukemia.

Blood 2014 Jul;124(1):5-6

ALBERT EINSTEIN COLLEGE OF MEDICINE.

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http://dx.doi.org/10.1182/blood-2014-05-572917DOI Listing
July 2014

Combinatorial haplo-deficient tumor suppression in 7q-deficient myelodysplastic syndrome and acute myeloid leukemia.

Cancer Cell 2014 May;25(5):555-7

Department of Cell Biology, Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY 10461, USA; Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY 10461, USA; Division of Hematologic Malignancies, Department of Medicine (Oncology), Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY 10461, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.04.018DOI Listing
May 2014

Stem cell fate regulation by dynein motor protein Lis1.

Nat Genet 2014 Mar;46(3):217-8

Department of Cell Biology, the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, the Department of Medicine (Oncology) and the Albert Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/ng.2902DOI Listing
March 2014

Eltrombopag for the treatment of thrombocytopenia in patients with malignant and non-malignant hematologic disorders.

Expert Opin Drug Metab Toxicol 2013 Dec 12;9(12):1667-75. Epub 2013 Nov 12.

Albert Einstein College of Medicine, Division of Hematologic Malignancies, Department of Medicine (Oncology) , 1300 Morris Park Avenue, Bronx, NY , USA.

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http://dx.doi.org/10.1517/17425255.2013.858119DOI Listing
December 2013

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Nucleic Acids Res 2013 Sep 16;41(16):e157. Epub 2013 Jul 16.

Cancer Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA, Department of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA, Department of Pathology, Johns Hopkins School of Medicine, 1550 Orleans Street, Baltimore MD 21231, USA, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA and Department of Medicine, Hematology and Medical Oncology, Mount Sinai School of Medicine, 1470 Madison Avenue, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/nar/gkt601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763560PMC
September 2013

Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells.

Stem Cells Transl Med 2013 Feb 24;2(2):143-50. Epub 2013 Jan 24.

Department of Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.

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http://dx.doi.org/10.5966/sctm.2012-0109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659760PMC
February 2013

HLX in AML: novel prognostic and therapeutic target.

Oncotarget 2012 Oct 11;3(10):1059-60. Epub 2012 Oct 11.

Department of Cell Biology, Albert Einstein Cancer Center, and Ruth L. and David S. Gottesman Institute for Stem Cell Research and Regenerative MedicineBronx, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717949PMC
http://dx.doi.org/10.18632/oncotarget.705DOI Listing
October 2012

Multi-parameter fluorescence-activated cell sorting and analysis of stem and progenitor cells in myeloid malignancies.

Best Pract Res Clin Haematol 2010 Sep;23(3):391-401

Albert Einstein College of Medicine, Department of Cell Biology & Albert Einstein Cancer Center, Chanin Institute for Cancer Research, Rm. #606, 1300 Morris Park Avenue, NY 10461, USA.

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http://dx.doi.org/10.1016/j.beha.2010.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052971PMC
September 2010

Use of RNA interference to inhibit integrin subunit alphaV-mediated angiogenesis.

Angiogenesis 2005 7;8(4):361-72. Epub 2006 Jan 7.

Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Germany.

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http://dx.doi.org/10.1007/s10456-005-9026-5DOI Listing
March 2009

Coexpression of fragile histidine triad and c-kit is relevant for prediction of survival in patients with small cell lung cancer.

Cancer Epidemiol Biomarkers Prev 2006 Nov;15(11):2232-8

Klinik für Hämatologie, Onkologie und klinische Immunologie, Heinrich-Heine-Universität Düsseldorf, Dusseldorf, Germany.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-06-0342DOI Listing
November 2006