Ulrich Specks

Ulrich Specks

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Ulrich Specks

Ulrich Specks

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Subclassifying ANCA-associated vasculitis: a unifying view of disease spectrum.

Rheumatology (Oxford) 2019 Oct;58(10):1707-1709

Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/rheumatology/kez148DOI Listing
October 2019

The Incidence of Arterial and Venous Thrombosis in Antineutrophil Cytoplasmic Antibody-associated Vasculitis.

J Rheumatol 2019 Sep 1;46(9):1243. Epub 2019 Jul 1.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, and INSERM UMR1227, Lymphocytes B et Autoimmunité, Université de Bretagne Occidentale, CHU de Brest, Brest, France.

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http://dx.doi.org/10.3899/jrheum.181351DOI Listing
September 2019

Update on the Management of Respiratory Manifestations of the Antineutrophil Cytoplasmic Antibodies-Associated Vasculitides.

Clin Chest Med 2019 Sep;40(3):573-582

Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccm.2019.05.012DOI Listing
September 2019

Evaluation of Potential Serum Biomarkers of Disease Activity in Diverse Forms of Vasculitis.

J Rheumatol 2019 Sep 1. Epub 2019 Sep 1.

From Boston University, Boston, MA, USA; University of Arizona, Tucson, AZ, USA; University of Michigan, Ann Arbor, MI, USA; University of South Florida, Tampa, FL, USA; Mount Sinai Hospital, Toronto, Ontario, Canada; McMaster University, Hamilton, Ontario, Canada; University of Utah, Salt Lake City, UT, USA; Cleveland Clinic, Cleveland, OH, USA; University of Pennsylvania, Philadelphia, PA, USA; University of Pittsburgh, Pittsburgh, PA, USA; Johns Hopkins University, Baltimore, MD, USA; Mayo Clinic, Rochester, MN, USA; VA Boston Healthcare System, Boston, MA, USA. This work was sponsored by the Vasculitis Clinical Research Consortium. The Vasculitis Clinical Research Consortium (VCRC) is part of the Rare Diseases Clinical Research Network (RDCRN), an initiative of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Science (NCATS). The VCRC is funded through collaboration between NCATS, and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), U54 AR057319), and has received funding from the National Center for Research Resources (U54 RR019497). Additional funding for this project included RC1 AR 058303 and P60 AR047785. Dr. Merkel reports receiving funds for the following activities: Consulting: AbbVie, AstraZeneca, Biogen, Boeringher-Ingelheim, Bristol-Myers Squibb, Celgene, ChemoCentryx, Genentech/Roche, Genzyme/Sanofi, GlaxoSmithKline, InflaRx, Insmed, Jannsen, Kiniksa; Research Support: AstraZeneca, Boeringher- Ingelheim, Bristol-Myers Squibb, Celgene, ChemoCentryx, Genentech/Roche, GlaxoSmithKline, Kypha, TerumoBCT; Royalties: UpToDate. Dr. Monach reports receiving funds for the following activities: Consulting: Celgene, ChemoCentryx. Address correspondence to Paul Monach, MD, PhD Rheumatology Section VA Boston Healthcare System 150 South Huntington Ave Boston, MA 02130. Email:

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http://dx.doi.org/10.3899/jrheum.190093DOI Listing
September 2019

Rituximab Versus Cyclophosphamide for Central Nervous System Involvement of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Case Series.

J Clin Rheumatol 2019 Sep 13. Epub 2019 Sep 13.

From the Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/RHU.0000000000001169DOI Listing
September 2019

Feasibility and Construct Validation of the Patient Reported Outcomes Measurement Information System in Systemic Vasculitis.

J Rheumatol 2019 Aug 1;46(8):928-934. Epub 2019 Mar 1.

From the Department of Epidemiology and Biostatistics, Faculty of Medicine, University of Iceland; Department of Rheumatology, and Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland; Department of Biostatistics, Epidemiology, and Informatics, and Division of Rheumatology, and Department of Family Medicine and Community Health, and Division of General Internal Medicine, University of Pennsylvania, Philadelphia; Division of Rheumatology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, Florida; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Department of Rheumatology, Cleveland Clinic, Cleveland; Ohio State University Wexner Medical Center, Columbus, Ohio; Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, and Division of Pulmonology and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Nuffield Department of Population Health, Health Services Research Unit (HSRU), and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford; Faculty of Health and Applied Sciences, University of the West of England, Bristol and School of Clinical Sciences, University of Bristol, Bristol, UK; Department of Rheumatology, University of Ottawa, Ottawa; Division of Rheumatology, Mount Sinai Hospital, Toronto; Division of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.171405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726391PMC
August 2019

Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.

J Am Soc Nephrol 2019 Jun 6;30(6):1123-1136. Epub 2019 May 6.

Sorbonne Université, Université Pierre et Marie Curie Paris 06, and Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche S1155, Paris, France; and.

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http://dx.doi.org/10.1681/ASN.2018080852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551791PMC
June 2019

Severe/uncontrolled asthma and overall survival in atopic patients with eosinophilic granulomatosis with polyangiitis.

Respir Med 2018 09 24;142:66-72. Epub 2018 Jul 24.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2018.07.017DOI Listing
September 2018

Risk of Cardiovascular Disease and Venous Thromboembolism Among Patients With Incident ANCA-Associated Vasculitis: A 20-Year Population-Based Cohort Study.

Mayo Clin Proc 2018 05 24;93(5):597-606. Epub 2018 Mar 24.

Division of Pulmonary and Critical Care Medicine, Rochester, MN; INSERM UMR1227, Lymphocytes B et Autoimmunité, Université de Bretagne Occidentale, CHU de Brest, Brest, France.

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http://dx.doi.org/10.1016/j.mayocp.2018.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057792PMC
May 2018

Reply.

Arthritis Rheumatol 2017 11;69(11):2247-2248

Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1002/art.40220DOI Listing
November 2017

Identification and phenotyping of circulating autoreactive proteinase 3-specific B cells in patients with PR3-ANCA associated vasculitis and healthy controls.

J Autoimmun 2017 Nov 1;84:122-131. Epub 2017 Sep 1.

Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.08.006DOI Listing
November 2017

Reply.

Arthritis Rheumatol 2017 07 31;69(7):1507-1508. Epub 2017 May 31.

Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1002/art.40121DOI Listing
July 2017

Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.

N Engl J Med 2017 05;376(20):1921-1932

From the Department of Medicine, National Jewish Health, Denver (M.E.W.); the Division of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego, La Jolla (P.A.); Beth Israel Deaconess Medical Center, Boston (P.A., P.F.W.); the Department of Medicine, University of Cambridge, Cambridge (D.J.), the Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford (R.L.), Research and Development, Immuno-Inflammation Therapy Area Unit (J.B.), and Research and Development, Statistics, Programming, and Data Standards (S.M.), GlaxoSmithKline, Uxbridge, and Trizell, Oxford (R.P.) - all in the United Kingdom; the Human Eosinophil Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (P.K., A.K.); the Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland (C.A.L.); the Division of Rheumatology and the Department of Biostatistics and Clinical Epidemiology, University of Pennsylvania (P.A.M.), and the Respiratory Therapy Area Unit and Flexible Discovery Unit, GlaxoSmithKline (J.S.), Philadelphia; Rheumazentrum, Schleswig-Holstein Mitte, Neumünster, Germany (F.M.); the Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN (U.S.); the Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clinic University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona (M.C.C.); the Respiratory Therapeutic Area, GlaxoSmithKline, Research Triangle Park, NC (S.W.Y.); and the Departments of Dermatology and Medicine, University of Utah School of Medicine, Salt Lake City (G.J.G.).

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http://dx.doi.org/10.1056/NEJMoa1702079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548295PMC
May 2017

Clinical trials in antineutrophil cytoplasmic antibody-associated vasculitis: what we have learnt so far, and what we still have to learn.

Nephrol Dial Transplant 2017 Jan;32(suppl_1):i37-i47

Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic Rochester, MN, USA.

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http://dx.doi.org/10.1093/ndt/gfw384DOI Listing
January 2017

Complement activation in pauci-immune necrotizing and crescentic glomerulonephritis: results of a proteomic analysis.

Nephrol Dial Transplant 2017 Jan;32(suppl_1):i139-i145

Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://academic.oup.com/ndt/article/32/suppl_1/i139/2930785
Publisher Site
http://dx.doi.org/10.1093/ndt/gfw299DOI Listing
January 2017

Reply.

Arthritis Rheumatol 2016 11;68(11):2828-2829

Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1002/art.39825DOI Listing
November 2016

Non-ischemic cardiomyopathy after rituximab treatment for membranous nephropathy.

J Renal Inj Prev 2017 2;6(1):18-25. Epub 2016 Nov 2.

Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://journalrip.com/Abstract/JRIP_20161105104524
Publisher Site
http://dx.doi.org/10.15171/jrip.2017.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414514PMC
November 2016

ANCA-associated vasculitis - clinical utility of using ANCA specificity to classify patients.

Nat Rev Rheumatol 2016 10 28;12(10):570-9. Epub 2016 Jul 28.

Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1038/nrrheum.2016.123DOI Listing
October 2016

Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.

Pharmacol Rev 2016 07;68(3):603-30

INSERM U-1100, Centre d'Etude des Pathologies Respiratoires and Université François Rabelais, Tours, France (B.K., C.G., F.G.); Faculty of Chemistry, University of Gdansk, Gdansk, Poland (A.L., M.W.); Architecture et Fonction des Macromolécules Biologiques, Unité Mixte de Recherche 7257, Marseille, France (C.K.); Génétique, Immunothérapie, Chimie et Cancer, Unité Mixte de Recherche 7292, Université François Rabelais, Tours, France (H.W.); Thoracic Diseases Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, Rochester, Minnesota (U.S.); Comprehensive Pneumology Center, Institute of Lung Biology and Disease, German Center for Lung Research, Munich, Germany (D.E.J.); and Max Planck Institute of Neurobiology, Planegg-Martinsried, Germany (D.E.J.).

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http://dx.doi.org/10.1124/pr.115.012104DOI Listing
July 2016

Biopsy-proven pulmonary capillaritis: A retrospective study of aetiologies including an in-depth look at isolated pulmonary capillaritis.

Respirology 2016 May 26;21(4):734-8. Epub 2016 Jan 26.

Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1111/resp.12738DOI Listing
May 2016

Serum biomarkers in patients with relapsing eosinophilic granulomatosis with polyangiitis (Churg-Strauss).

PLoS One 2015 26;10(3):e0121737. Epub 2015 Mar 26.

1st Medical Department and Ludwig Boltzmann Institute of Osteology, Hanusch Hospital, Vienna, Austria; Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121737PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374913PMC
March 2016

Vasculitis in patients with inflammatory bowel diseases: A study of 32 patients and systematic review of the literature.

Semin Arthritis Rheum 2016 Feb 26;45(4):475-82. Epub 2015 Jul 26.

Division of Rheumatology, Mount Sinai Hospital, University of Toronto, The Joseph and Wolf Lebovic Building, 60 Murray St, Ste 2-220, Toronto, Ontario, Canada M5T 3L9. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2015.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982464PMC
February 2016

Characterization of F-18 Fluorodeoxyglucose PET/CT in Granulomatosis with Polyangiitis.

Sarcoidosis Vasc Diffuse Lung Dis 2016 Jan 18;32(4):342-52. Epub 2016 Jan 18.

Mayo Clinic.

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January 2016

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management.

Eur J Intern Med 2015 Sep 9;26(7):545-53. Epub 2015 May 9.

Department of Internal Medicine, National Referral Center for Rare Autoimmune and Systemic Diseases (Vasculitis, Scleroderma), INSERM U1016, Hôpital Cochin, APHP, Université Paris Descartes, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2015.04.022DOI Listing
September 2015

Reply: Further Progress in Understanding Fibrosing Mediastinitis.

Am J Respir Crit Care Med 2015 Sep;192(6):768

1 Mayo Clinic Rochester, Minnesota.

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http://dx.doi.org/10.1164/rccm.201506-1183LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595682PMC
September 2015

Cardiac Involvement in Granulomatosis with Polyangiitis.

J Rheumatol 2015 Jul 1;42(7):1209-12. Epub 2015 May 1.

From the Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario, Canada; Health Informatics Institute, University of South Florida, Tampa, Florida; Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio, USA; Division of Rheumatology, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology, University of Pennsylvania, Philadelphia; Division of Rheumatology, University of Pittsburgh, Pennsylvania; The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; Division of Pulmonary and Critical Care Medicine, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.L. McGeoch, MD; S. Carette, MD, Division of Rheumatology, Mount Sinai Hospital; D. Cuthbertson, MS, Health Informatics Institute, University of South Florida; G.S. Hoffman, MD, Center for Vasculitis Care and Research, Cleveland Clinic; N. Khalidi, MD, Division of Rheumatology, McMaster University; C.L. Koening, MD, Division of Rheumatology, University of Utah; C.A. Langford, MD, Center for Vasculitis Care and Research, Cleveland Clinic; C.A. McAlear, MA, Division of Rheumatology, University of Pennsylvania; L. Moreland, MD, Division of Rheumatology, University of Pittsburgh; P.A. Monach, MD, PhD, The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine; P. Seo, MD, Division of Rheumatology, Johns Hopkins University; U. Specks, MD, Division of Pulmonary and Critical Care Medicine; S.R. Ytterberg, MD, Division of Rheumatology, Mayo Clinic College of Medicine; P.A. Merkel, MD, MPH, Division of Rheumatology, University of Pennsylvania; C. Pagnoux, MD, MSc, MPH, Division of Rheumatology, Mount Sinai Hospital.

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http://dx.doi.org/10.3899/jrheum.141513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505809PMC
July 2015

Pro: Should all patients with anti-neutrophil cytoplasmic antibody-associated vasculitis be primarily treated with rituximab?

Authors:
Ulrich Specks

Nephrol Dial Transplant 2015 Jul 21;30(7):1083-7. Epub 2015 May 21.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1093/ndt/gfv217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479669PMC
July 2015

Opponent's comments.

Authors:
Ulrich Specks

Nephrol Dial Transplant 2015 Jul;30(7):1081-2

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1093/ndt/gfv216aDOI Listing
July 2015

Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis.

J Autoimmun 2015 May 3;59:43-52. Epub 2015 Mar 3.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease (iLBD), University Hospital, Ludwig Maximilians University and Helmholtz Zentrum München, Member of the German Center of Lung Research, Max-Lebsche-Platz 31, 81377 Munich, Germany; Max Planck Institute of Neurobiology, Planegg-Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.02.002DOI Listing
May 2015

Can antineutrophil cytoplasmic antibody levels be used to inform treatment of pauci-immune vasculitis?

Curr Opin Rheumatol 2015 May;27(3):231-40

Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000170DOI Listing
May 2015

Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement.

J Am Soc Nephrol 2015 Apr 7;26(4):976-85. Epub 2014 Nov 7.

Division of Pulmonary and Critical Care Medicine and Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota;

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http://dx.doi.org/10.1681/ASN.2014010046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378104PMC
April 2015

Isolated pauciimmune pulmonary capillaritis successfully treated with rituximab.

Chest 2015 Apr;147(4):e134-e136

Mayo Clinic, Rochester, MN; Department of Medicine and Division of Pulmonary and Critical Care Medicine Rochester, MN. Electronic address:

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http://dx.doi.org/10.1378/chest.14-1884DOI Listing
April 2015

Accurate relapse prediction in ANCA-associated vasculitis-the search for the Holy Grail.

Authors:
Ulrich Specks

J Am Soc Nephrol 2015 Mar 16;26(3):505-7. Epub 2014 Oct 16.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1681/ASN.2014080817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341490PMC
March 2015

Pituitary dysfunction in granulomatosis with polyangiitis: the Mayo Clinic experience.

J Clin Endocrinol Metab 2014 Nov 31;99(11):3988-94. Epub 2014 Jul 31.

Divisions of General Internal Medicine (E.K.), Pulmonary and Critical Care Medicine (R.C.-C., U.S.) Ophthalmology (J.L.), Radiology (B.E.), and Endocrinology (D.E.), Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/jc.2014-1962DOI Listing
November 2014

Experience with rituximab in the treatment of antineutrophil cytoplasmic antibody associated vasculitis.

Ther Adv Musculoskelet Dis 2014 Apr;6(2):58-74

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1177/1759720X13516239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956138PMC
April 2014

Coexistent pulmonary granulomatosis with polyangiitis (Wegener granulomatosis) and Crohn disease.

Am J Surg Pathol 2014 Mar;38(3):354-9

*Division of Thoracic Medicine #Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ †Section of Rheumatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH Divisions of ‡Thoracic Medicine §Rheumatology ∥Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN ¶Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000135DOI Listing
March 2014

Treatment of ANCA-associated vasculitis: new therapies and a look at old entities.

Adv Chronic Kidney Dis 2014 Mar;21(2):182-93

Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; and Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1053/j.ackd.2014.01.009DOI Listing
March 2014

Primary antiphospholipid syndrome-associated diffuse alveolar hemorrhage.

Arthritis Care Res (Hoboken) 2014 Feb;66(2):301-10

Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/acr.22109DOI Listing
February 2014

New features of disease after diagnosis in 6 forms of systemic vasculitis.

J Rheumatol 2013 Nov 1;40(11):1905-12. Epub 2013 Aug 1.

From The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts; Department of Biostatistics, University of South Florida, Tampa, Florida; Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario; and the Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio; Division of Rheumatology, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology, University of Pittsburgh; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester; Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota; and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.3899/jrheum.121473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292850PMC
November 2013

A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.

J Biol Chem 2013 Sep 31;288(37):26635-48. Epub 2013 Jul 31.

From the Comprehensive Pneumology Center, Institute of Lung Biology and Disease (iLBD), University Hospital, Ludwig Maximilians University and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Max-Lebsche-Platz 31, 81377 Munich, Germany.

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http://dx.doi.org/10.1074/jbc.M113.495770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772210PMC
September 2013

Pneumocystis pneumonia in patients treated with rituximab.

Chest 2013 Jul;144(1):258-265

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1378/chest.12-0477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694106PMC
July 2013

S1. Rituximab for ANCA-associated vasculitis: the experience in the United States.

Presse Med 2013 Apr 7;42(4 Pt 2):530-2. Epub 2013 Mar 7.

Mayo Clinic, Division of Pulmonary and Critical Care Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.lpm.2013.01.048DOI Listing
April 2013

Otorhinolaryngological manifestations in granulomatosis with polyangiitis (Wegener's).

Autoimmun Rev 2013 Feb 23;12(4):501-5. Epub 2012 Aug 23.

Department of Otorhinolaryngology, San Raffaele Scientific Institute, Milan, Italy, IRCCS.

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http://dx.doi.org/10.1016/j.autrev.2012.08.010DOI Listing
February 2013

Vasculitis: Refining phenotypes in ANCA-associated vasculitis.

Nat Rev Nephrol 2013 Jan 20;9(1):6-8. Epub 2012 Nov 20.

Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55901, USA.

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http://dx.doi.org/10.1038/nrneph.2012.261DOI Listing
January 2013

Pathogenesis of ANCA-associated vasculitis.

Curr Rheumatol Rep 2012 Dec;14(6):481-93

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1007/s11926-012-0286-yDOI Listing
December 2012

TNF-α blocker therapy and solid malignancy risk in ANCA-associated vasculitis.

Curr Rheumatol Rep 2012 Dec;14(6):501-8

Departamento de Inmunología Clínica y Reumatología, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 352, Santiago, Chile.

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http://link.springer.com/content/pdf/10.1007%2Fs11926-012-02
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http://link.springer.com/10.1007/s11926-012-0290-2
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http://dx.doi.org/10.1007/s11926-012-0290-2DOI Listing
December 2012

Update on diffuse alveolar hemorrhage and pulmonary vasculitis.

Immunol Allergy Clin North Am 2012 Nov 28;32(4):587-600. Epub 2012 Sep 28.

Department of Internal Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.iac.2012.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483562PMC
November 2012

Biologic agents in the treatment of granulomatosis with polyangiitis.

Authors:
Ulrich Specks

Cleve Clin J Med 2012 Nov;79 Suppl 3:S50-3

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 45905, USA.

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http://dx.doi.org/10.3949/ccjm.79.s3.11DOI Listing
November 2012

Controversies in ANCA testing.

Authors:
Ulrich Specks

Cleve Clin J Med 2012 Nov;79 Suppl 3:S7-11

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 45905, USA.

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http://dx.doi.org/10.3949/ccjm.79.s3.02DOI Listing
November 2012

Histopathologic Overlap between Fibrosing Mediastinitis and IgG4-Related Disease.

Int J Rheumatol 2012 10;2012:207056. Epub 2012 May 10.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1155/2012/207056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357960PMC
August 2012

Vasculitis: Will LAMP enlighten us about ANCA-associated vasculitis?

Nat Rev Nephrol 2012 Apr 24;8(6):318-20. Epub 2012 Apr 24.

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http://dx.doi.org/10.1038/nrneph.2012.85DOI Listing
April 2012