Ulrich Pfeffer

Ulrich Pfeffer

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Ulrich Pfeffer

Ulrich Pfeffer

Publications by authors named "Ulrich Pfeffer"

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Targeted Therapy of Uveal Melanoma: Recent Failures and New Perspectives.

Cancers (Basel) 2019 Jun 18;11(6). Epub 2019 Jun 18.

IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.

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http://dx.doi.org/10.3390/cancers11060846DOI Listing
June 2019

miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A.

J Exp Clin Cancer Res 2019 Jun 21;38(1):272. Epub 2019 Jun 21.

Laboratory of Molecular Oncology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, Via dei Monti di Creta 104, 00167, Rome, Italy.

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http://dx.doi.org/10.1186/s13046-019-1238-4DOI Listing
June 2019

Circulating healing (CH) cells expressing BST2 are functionally activated by the injury-regulated systemic factor HGFA.

Stem Cell Res Ther 2018 11 8;9(1):300. Epub 2018 Nov 8.

Cellular Oncology Laboratory, Department of Experimental Medicine (DIMES), University of Genova, Largo Rosanna Benzi 10, 16132, Genova, Italy.

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http://dx.doi.org/10.1186/s13287-018-1056-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225669PMC
November 2018

Metastatic melanoma: how research can modify the course of a disease.

Cancer Metastasis Rev 2017 03;36(1):3-5

Department of Integrated Oncological Therapies, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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http://dx.doi.org/10.1007/s10555-017-9664-2DOI Listing
March 2017

The biology of uveal melanoma.

Cancer Metastasis Rev 2017 03;36(1):109-140

Laboratory of Molecular Pathology, Department of Integrated Oncology Therapies, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, L.go Rosanna Benzi 10, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s10555-017-9663-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385203PMC
March 2017

SNP variants at the MAP3K1/SETD9 locus 5q11.2 associate with somatic PIK3CA variants in breast cancers.

Eur J Hum Genet 2017 02 28;25(3):384-387. Epub 2016 Dec 28.

Integrated Oncology Therapies Department, Molecular Pathology, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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http://dx.doi.org/10.1038/ejhg.2016.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315515PMC
February 2017

Molecular evolution of colorectal cancer: from multistep carcinogenesis to the big bang.

Cancer Metastasis Rev 2016 Mar;35(1):63-74

Molecular Pathology, IRCCS AOU San Martino-IST-Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi 10, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s10555-016-9606-4DOI Listing
March 2016

Potential Role of Soluble c-Met as a New Candidate Biomarker of Metastatic Uveal Melanoma.

JAMA Ophthalmol 2015 Sep;133(9):1013-21

Department of Integrated Oncology Therapies, Istituto di Ricovero e Cura a Carattere Scientifico, Azienda Ospedaliera Universitaria San Martino-Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.

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http://dx.doi.org/10.1001/jamaophthalmol.2015.1766DOI Listing
September 2015

ADAM10 correlates with uveal melanoma metastasis and promotes in vitro invasion.

Pigment Cell Melanoma Res 2014 Nov 11;27(6):1138-48. Epub 2014 Sep 11.

IRCCS A.O.U. San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.

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http://dx.doi.org/10.1111/pcmr.12306DOI Listing
November 2014

Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel.

Cancer Metastasis Rev 2014 Sep;33(2-3):657-71

Functional Genomics, IRCCS A.O.U. San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.

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http://dx.doi.org/10.1007/s10555-013-9470-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113682PMC
September 2014

Paradoxic effects of metformin on endothelial cells and angiogenesis.

Carcinogenesis 2014 May 13;35(5):1055-66. Epub 2014 Jan 13.

Department of Research and Statistics Infrastructure, IRCCS "Tecnologie Avanzate e Modelli Assistenziali in Oncologia"Arcispedale S. Maria Nuova, 42123 Reggio Emilia, Italy.

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http://dx.doi.org/10.1093/carcin/bgu001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004203PMC
May 2014

Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2.

Carcinogenesis 2012 Dec 5;33(12):2507-19. Epub 2012 Oct 5.

Institute of Laboratory Medicine (former Dept. of Clin. Chemistry and Biochemistry), Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1093/carcin/bgs312DOI Listing
December 2012

Effects of bicalutamide and 4OH-tamoxifen on androgen-regulated gene expression in the LNCaP cell line.

Anticancer Res 2012 Dec;32(12):5323-9

Department of Medical Oncology, IRCCS SAN Martino Hospital - IST National Cancer Research Institute, Largo R. Benzi 10, 16132 Genoa, Italy.

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December 2012

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125.

Biochem Pharmacol 2012 Sep 13;84(5):598-611. Epub 2012 Jun 13.

Laboratory of Molecular Oncology, Istituto Dermopatico dell'Immacolata-IRCCS, Via dei Monti di Creta 104, 00167 Rome, Italy.

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http://dx.doi.org/10.1016/j.bcp.2012.06.004DOI Listing
September 2012

Interplay between histopathological alterations, cigarette smoke and chemopreventive agents in defining microRNA profiles in mouse lung.

Mutat Res 2011 Dec 23;717(1-2):17-24. Epub 2010 Oct 23.

Department of Health Sciences, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2010.10.003DOI Listing
December 2011

Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.

PLoS One 2011 26;6(5):e20550. Epub 2011 May 26.

Department of Clinical Chemistry and Clinical Biochemistry, Ludwig-Maximilians-University, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102747PMC
September 2011

Reference profile correlation reveals estrogen-like trancriptional activity of Curcumin.

Cell Physiol Biochem 2010 24;26(3):471-82. Epub 2010 Aug 24.

Department of Clinical Chemistry and Clinical Biochemistry, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1159/000320570DOI Listing
December 2010

International Society for Eye Research--XIXth Biennial Meeting.

Authors:
Ulrich Pfeffer

IDrugs 2010 Sep;13(9):619-21

National Cancer Research Institute, Largo Rosanna Benzi 10, Genoa, Italy.

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September 2010

Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs.

Clin Exp Metastasis 2010 Aug 10;27(6):419-39. Epub 2010 Apr 10.

MultiMedica Castellanza (VA) and Oncology Research, IRCCS MultiMedica, 20138 Milan, Italy.

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http://dx.doi.org/10.1007/s10585-010-9312-5DOI Listing
August 2010

In vivo growth inhibition of head and neck squamous cell carcinoma by the Interferon-inducible gene IFI16.

Cancer Lett 2010 Jan 23;287(1):33-43. Epub 2009 Jun 23.

Department of Public Health and Microbiology, Medical School of Turin, Via Santena 9, 10126 Turin, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.05.035DOI Listing
January 2010

Novel aspects for the application of Curcumin in chemoprevention of various cancers.

Front Biosci (Schol Ed) 2010 Jan 1;2:697-717. Epub 2010 Jan 1.

Department of Clinical Chemistry and Clinical Biochemistry, Ludwig-Maximilians University Munich, München, Germany.

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January 2010

Survival Online: a web-based service for the analysis of correlations between gene expression and clinical and follow-up data.

BMC Bioinformatics 2009 Oct 15;10 Suppl 12:S10. Epub 2009 Oct 15.

University of Genoa, Department of Communication, Computer and System Sciences, Viale Causa 13, Genoa, Italy.

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http://dx.doi.org/10.1186/1471-2105-10-S12-S10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762059PMC
October 2009

Prediction of breast cancer metastasis by genomic profiling: where do we stand?

Clin Exp Metastasis 2009 24;26(6):547-58. Epub 2009 Mar 24.

Functional Genomics, National Cancer Research Institute, Genoa, Italy.

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http://dx.doi.org/10.1007/s10585-009-9254-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717389PMC
August 2009

Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke.

Am J Physiol Lung Cell Mol Physiol 2009 Mar 31;296(3):L418-29. Epub 2008 Dec 31.

Dipartimento di Fisiopatologia, Medicina Sperimentale e Sanità Pubblica, Università di Siena, Siena, Italy.

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http://dx.doi.org/10.1152/ajplung.90382.2008DOI Listing
March 2009

Lineage infidelity and expression of melanocytic markers in human breast cancer.

Int J Oncol 2008 Nov;33(5):1011-5

Department of Clinical Chemistry and Clinical Biochemistry, Ludwig-Maximilians-University, Munich, Germany.

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November 2008

Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB.

Carcinogenesis 2008 Apr 13;29(4):779-89. Epub 2007 Nov 13.

Department of Clinical Chemistry and Clinical Biochemistry, Ludwig-Maximilians-University Munich, D-80336 München, Germany.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgm248DOI Listing
April 2008

Metastasis signatures: genes regulating tumor-microenvironment interactions predict metastatic behavior.

Cancer Metastasis Rev 2008 Mar;27(1):75-83

IRCCS MultiMedica, Scientific and Technological Pole, Via Fantoli 16/15, 20138, Milan, Italy.

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http://link.springer.com/10.1007/s10555-007-9111-x
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http://dx.doi.org/10.1007/s10555-007-9111-xDOI Listing
March 2008

Endothelial cell aging and apoptosis in prevention and disease: E-selectin expression and modulation as a model.

Curr Pharm Des 2008 ;14(3):221-5

Department of Clinical and Biological Sciences, Università degli studi Dell'Insubria, School of Medicine, Varese, Italy.

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February 2008

HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials.

J Natl Cancer Inst 2008 Jan 25;100(1):14-20. Epub 2007 Dec 25.

National Cancer Research Institute, Largo Rosanna Benzi, 10 16132 Genoa, Italy.

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djm252DOI Listing
January 2008

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice.

Cell Physiol Biochem 2007 ;19(1-4):137-52

Department of Clinical Chemistry and Clinical Biochemistry, Surgical Hospital, Ludwig-Maximilians-University Munich, Germany.

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http://dx.doi.org/10.1159/000099202DOI Listing
April 2007

Identification of genes selectively regulated by IFNs in endothelial cells.

J Immunol 2007 Jan;178(2):1122-35

Department of Oncology and Surgical Sciences, Istituto Oncologico Veneto, Via Gattemelata 64, I-35128 Padua, Italy.

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http://dx.doi.org/10.4049/jimmunol.178.2.1122DOI Listing
January 2007

Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: microarray gene expression analyses.

Mutat Res 2005 Dec 5;591(1-2):198-211. Epub 2005 Aug 5.

Functional Genomics Unit, National Cancer Research Institute, Genova, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.04.014DOI Listing
December 2005

Transcriptional control of cell density dependent regulation of matrix metalloproteinase and TIMP expression in breast cancer cell lines.

Thromb Haemost 2005 Apr;93(4):761-9

Dept. of Clinical Chemistry and Clinical Biochemistry, Surgical Hospital, Ludwig-Maximilians-University, Nussbaumstr. 20, D-80336 München, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH04-09-0601
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http://dx.doi.org/10.1160/TH04-09-0601DOI Listing
April 2005

Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate.

Biochem Pharmacol 2004 Dec;68(12):2359-66

Molecular Oncology, National Cancer Research Institute (IST), Largo Rosanna Benzi 10, 16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.bcp.2004.08.021DOI Listing
December 2004

Inhibition of Kaposi's sarcoma in vivo by fenretinide.

Clin Cancer Res 2003 Dec;9(16 Pt 1):6020-9

Molecular Oncology Laboratory, the National Institute for Cancer Research, Genova, Italy.

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December 2003

Alternative splicing of the human estrogen receptor alpha primary transcript: mechanisms of exon skipping.

Int J Mol Med 2003 Sep;12(3):355-63

Laboratory of Molecular Oncology, National Cancer Research Institute, I-16132 Genova, Italy.

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September 2003

Inhibition of tumor angiogenesis by angiostatin: from recombinant protein to gene therapy.

Endothelium 2002 ;9(1):3-10

Laboratory of Molecular Biology, National Cancer Research Institute, Genoa, Italy.

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August 2003

Re: Microarray studies challenge theories of metastasis.

J Natl Cancer Inst 2003 Jun;95(11):829

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http://dx.doi.org/10.1093/jnci/95.11.829DOI Listing
June 2003

Kaposi's sarcoma and human chorionic gonadotropin: mechanisms, moieties and mysteries.

Biol Chem 2002 Sep;383(9):1315-20

Laboratory of Molecular Biology, National Cancer Research Institute, Genova, Italy.

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http://dx.doi.org/10.1515/BC.2002.149DOI Listing
September 2002

Human chorionic gonadotropin inhibits Kaposi's sarcoma associated angiogenesis, matrix metalloprotease activity, and tumor growth.

Endocrinology 2002 Aug;143(8):3114-21

Laboratory of Molecular Biology, National Cancer Research Institute Genova, c/o Advanced Biotechnology Center Genova, Large Rosanna Benzi 10, Genoa 16132, Italy.

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http://dx.doi.org/10.1210/endo.143.8.8945DOI Listing
August 2002

The androgen receptor CAG repeat: a modifier of carcinogenesis?

Mol Cell Endocrinol 2002 Jul;193(1-2):109-20

Laboratory of Molecular Biology, National Cancer Research Institute, Largo R. Benzi 10, 16132 Genoa, Italy.

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July 2002