Ulrich Kintscher

Ulrich Kintscher

UNVERIFIED PROFILE

Are you Ulrich Kintscher?   Register this Author

Register author
Ulrich Kintscher

Ulrich Kintscher

Publications by authors named "Ulrich Kintscher"

Are you Ulrich Kintscher?   Register this Author

100Publications

1477Reads

41Profile Views

Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage.

Hypertension 2019 Aug 10;74(2):295-304. Epub 2019 Jul 10.

From the Charité-Universitätsmedizin Berlin, corporate member of Freie Universitaät Berlin, Humboldt-Universitaät zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany (N.B., A.F.-L., S.B., J.G., Arne Thiele, U.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.12956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635061PMC
August 2019

Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse.

Front Endocrinol (Lausanne) 2018 4;9:732. Epub 2018 Dec 4.

Department of Molecular Toxicology, German Institute of Human Nutrition Potsdam-Rehbruecke, Potsdam, Germany.

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fendo.2018.00732
Publisher Site
http://dx.doi.org/10.3389/fendo.2018.00732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289062PMC
December 2018

ATR (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat.

Hypertension 2018 09;72(3):e20-e29

From the Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Germany (C.L., M.S., U.K., E.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11168DOI Listing
September 2018

The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics.

Exp Neurol 2018 08 21;306:34-44. Epub 2018 Apr 21.

Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Klinik für Psychiatrie und Psychotherapie, 10117 Berlin, Germany; Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsmedizin Rostock, 18147 Rostock, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2018.04.004DOI Listing
August 2018

Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals.

Cardiovasc Ultrasound 2018 Jul 3;16(1):10. Epub 2018 Jul 3.

Institute of Pharmacology, Center for Cardiovascular Research, Charité -Universitaetsmedizin Berlin, Hessische Str. 3-4, 10115, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12947-018-0128-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029342PMC
July 2018

Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity.

Hypertension 2018 04 5;71(4):599-608. Epub 2018 Feb 5.

From the Department of Medicine/Cardiology, Deutsches Herzzentrum Berlin, Germany (J.G., P.S.); Institute of Pharmacology, Center for Cardiovascular Research, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (J.G., N.B., E.S., R.C., A.B., Z.B., S.B., I.R.B., M.S., A.F.-L., U.K.); DZHK (German Centre for Cardiovascular Research), partner site Berlin (J.G., N.B., E.S., A.B., S.B., I.R.B., A.F.-L., U.K.); Department of Veterinary Pathology, Freie Universität Berlin, Germany (R.K.); Pamgene International B.V., s-Hertogenbosch, The Netherlands (R.H.); and Cardiology Research, Bayer AG, Wuppertal, Germany (P.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10360DOI Listing
April 2018

Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.

Circ Res 2018 03 22;122(5):693-700. Epub 2018 Jan 22.

From the Cardiology and Angiology I, University Heart Center and Medical Center (N.A.M., C.C., B.D., N.H., K.P., T.M., F.W., P.S., I.H., T.H., C.v.z.M., C.B., A.Z., D.W.), Faculty of Biology (N.A.M.), Department of Radiology, Medical Physics, Medical Center (D.v.E.), Hematology and Oncology (D.P.), and Department of Urology (R.S.), University of Freiburg, Germany; Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (K.B., A.B.P., E.E., K.L., D.W.); Neurosurgery, University of Erlangen, Germany (B.S.); Center for Cardiovascular Research (U.K.) and Department of Endocrinology & Metabolism, Center for Cardiovascular Research (CCR), Germany (S.B.), Charité-Universitätsmedizin Berlin, Germany; and Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Berlin, Germany (S.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.117.312055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834385PMC
March 2018

Application of Speckle-Tracking Echocardiography in an Experimental Model of Isolated Subendocardial Damage.

J Am Soc Echocardiogr 2017 Dec 21;30(12):1239-1250.e2. Epub 2017 Oct 21.

Institute of Pharmacology, Center for Cardiovascular Research, Charité - Universitaetsmedizin Berlin, Berlin, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung (German Centre for Cardiovascular Research), Partner site Berlin, Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.echo.2017.08.006DOI Listing
December 2017

AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice.

Clin Sci (Lond) 2017 Aug 13;131(15):1989-2005. Epub 2017 Jul 13.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin; and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research (CCR), Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/CS20170131DOI Listing
August 2017

PCSK9 regulates the chemokine receptor CCR2 on monocytes.

Biochem Biophys Res Commun 2017 04 20;485(2):312-318. Epub 2017 Feb 20.

Department of Medicine/Cardiology, Deutsches Herzzentrum Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2017.02.085DOI Listing
April 2017

Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPARγ agonists.

Eur J Med Chem 2017 Jan 25;126:590-603. Epub 2016 Nov 25.

Department of Pharmaceutical Chemistry, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, CCB - Centrum for Chemistry and Biomedicine, Innrain 80-82, 6020 Innsbruck, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmech.2016.11.051DOI Listing
January 2017

New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile.

Eur J Med Chem 2016 Nov 15;124:138-152. Epub 2016 Aug 15.

Pharmaceutical Chemistry, Institute of Pharmacy, Universität Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmech.2016.08.027DOI Listing
November 2016

ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss.

Metabolism 2016 Jun 7;65(6):935-43. Epub 2016 Apr 7.

Department of Endocrinology & Metabolism, Charite - Universitätsmedizin, Berlin, Germany; Charité-Center for Cardiovascular Research (CCR), Berlin, Germany; Experimental and Clinical Research Center (ECRC), Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.metabol.2016.03.013DOI Listing
June 2016

Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists Cause Differential Cardiac Gene Expression in Pressure Overload-induced Cardiac Hypertrophy.

J Cardiovasc Pharmacol 2016 05;67(5):402-11

*Institute of Pharmacology, Center for Cardiovascular Research, Charité-Universitaetsmedizin Berlin, Berlin, Germany; †Department of Veterinary Pathology, College of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany; ‡DZHK (German Center for Cardiovascular Research), partner site Berlin, Berlin, Germany; and §Department of Cardiology Research, Bayer Health Care, Wuppertal, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FJC.0000000000000366DOI Listing
May 2016

Inhibition of Src homology 2 domain-containing phosphatase 1 increases insulin sensitivity in high-fat diet-induced insulin-resistant mice.

FEBS Open Bio 2016 Mar 4;6(3):179-89. Epub 2016 Jan 4.

Center for Cardiovascular Research/CCR Institute of Laboratory Medicine Clinical Chemistry and Pathobiochemistry Charité - Universitätsmedizin Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/2211-5463.12000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794785PMC
March 2016

Gender in cardiovascular diseases: impact on clinical manifestations, management, and outcomes.

Eur Heart J 2016 Jan 3;37(1):24-34. Epub 2015 Nov 3.

DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany Clinic for Cardiology and Angiology, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://eurheartj.oxfordjournals.org/content/ehj/early/2015/1
Web Search
http://eurheartj.oxfordjournals.org/lookup/doi/10.1093/eurhe
Publisher Site
http://dx.doi.org/10.1093/eurheartj/ehv598DOI Listing
January 2016

Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate.

J Biol Chem 2015 Sep 10;290(39):23603-15. Epub 2015 Aug 10.

From the Institute of Pharmacology, Center for Cardiovascular Research, Charité-Universitaetsmedizin Berlin, 10115 Berlin, Germany, the DZHK (German Center for Cardiovascular Research), 10115 Berlin, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M115.645341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583014PMC
September 2015

Benefit of Blood Pressure Control in Diabetic Patients.

Authors:
Ulrich Kintscher

Curr Hypertens Rep 2015 Jul;17(7):50

Center for Cardiovascular Research, CCR, Institute of Pharmacology, Charité - Universitaetsmedizin Berlin, Hessische Str.3-4, 10115, Berlin, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11906-015-0561-1DOI Listing
July 2015

[Therapy of hypertension--2015].

Dtsch Med Wochenschr 2015 May 28;140(11):835-42; quiz 843-4. Epub 2015 May 28.

Klinik für Innere Medizin III - Kardiologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum des Saarlandes.

View Article

Download full-text PDF

Source
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-102097
Publisher Site
http://dx.doi.org/10.1055/s-0041-102097DOI Listing
May 2015

Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice.

Mol Metab 2015 Apr 12;4(4):325-36. Epub 2015 Feb 12.

Center for Cardiovascular Research/CCR, Institute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Hessische Str. 3-4, 10115 Berlin, Charité - Universitätsmedizin Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2015.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354926PMC
April 2015

[Hypertension and diabetes: target blood pressure and blood pressure lowering by new antidiabetic drugs].

Dtsch Med Wochenschr 2014 Nov 19;139(48):2468-9. Epub 2014 Nov 19.

2Praxis für Prävention und Therapie, Villingen-Schwenningen.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0034-1387420DOI Listing
November 2014

The individualized obesity paradox.

Authors:
Ulrich Kintscher

J Am Coll Cardiol 2014 Mar 4;63(8):786-7. Epub 2013 Dec 4.

Pharmacology and Metabolic Research, Charité-Universitaetsmedizin Berlin, Center for Cardiovascular Research, Institute of Pharmacology, Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2013.10.069DOI Listing
March 2014

Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome.

J Mol Med (Berl) 2013 Jul 1;91(7):811-23. Epub 2013 May 1.

Center for Cardiovascular Research (CCR) and Institute of Pharmacology, Charité-Universitätsmedizin, Hessische Strasse 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-013-1034-0DOI Listing
July 2013

Sexual dimorphism in obesity-mediated left ventricular hypertrophy.

Am J Physiol Heart Circ Physiol 2013 Jul 10;305(2):H211-8. Epub 2013 May 10.

Center for Cardiovascular Research, Department of Pharmacology and Metabolic Research, Charité-Universitätsmedizin Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00593.2012DOI Listing
July 2013

Bezafibrate maintenance therapy in patients with advanced chronic hepatitis C.

Eur J Gastroenterol Hepatol 2013 May;25(5):594-600

University Hospital Charité, Campus Virchow-Klinikum, Department of Gastroenterology and Hepatology, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MEG.0b013e32835cc878DOI Listing
May 2013

Sex differences in exercise-induced cardiac hypertrophy.

Pflugers Arch 2013 May 17;465(5):731-7. Epub 2013 Feb 17.

Department of Translational Pharmacology, Center for Cardiovascular Research, Charité-Universitaetsmedizin Berlin, Hessische Str 3-4, 10115, Berlin, Germany.

View Article

Download full-text PDF

Source
http://search.proquest.com/openview/edc0184558f58eba52e3bcd1
Web Search
http://cardiovascres.oxfordjournals.org/content/cardiovascre
Web Search
http://link.springer.com/10.1007/s00424-013-1225-0
Publisher Site
http://dx.doi.org/10.1007/s00424-013-1225-0DOI Listing
May 2013

The burden of hypertension.

Authors:
Ulrich Kintscher

EuroIntervention 2013 May;9 Suppl R:R12-5

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4244/EIJV9SRA3DOI Listing
May 2013

Sex-specific mTOR signaling determines sexual dimorphism in myocardial adaptation in normotensive DOCA-salt model.

Hypertension 2013 Mar 21;61(3):730-6. Epub 2013 Jan 21.

Department of Nephrology and Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00276DOI Listing
March 2013

Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor.

J Biochem 2013 Feb 21;153(2):197-207. Epub 2012 Nov 21.

Department of Medicine/Cardiology, Deutsches Herzzentrum Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jb/mvs137DOI Listing
February 2013

Sex and sex hormone-dependent cardiovascular stress responses.

Hypertension 2013 Feb 26;61(2):270-7. Epub 2012 Nov 26.

Institute of Gender in Medicine, Charité Universitaetsmedizin, Hessische Strasse 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.189233DOI Listing
February 2013

Sex-specific differences in Type 2 Diabetes Mellitus and dyslipidemia therapy: PPAR agonists.

Handb Exp Pharmacol 2012 (214):387-410

Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-642-30726-3_18DOI Listing
January 2013

Characterization of telmisartan-derived PPARγ agonists: importance of moiety shift from position 6 to 5 on potency, efficacy and cofactor recruitment.

ChemMedChem 2012 Nov;7(11):1935-42

Institute of Pharmacology, Center for Cardiovascular Research, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin (Germany).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cmdc.201200337DOI Listing
November 2012

And in the end--Telmisartan directly binds to PPARγ.

Authors:
Ulrich Kintscher

Hypertens Res 2012 Jul 22;35(7):704-5. Epub 2012 Mar 22.

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/hr201235
Publisher Site
http://dx.doi.org/10.1038/hr.2012.35DOI Listing
July 2012

Reuptake inhibitors of dopamine, noradrenaline, and serotonin.

Authors:
Ulrich Kintscher

Handb Exp Pharmacol 2012 (209):339-47

Charité - Universitätsmedizin, Institute of Pharmacology, Berlin, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-3-642-24716-3_15
Publisher Site
http://dx.doi.org/10.1007/978-3-642-24716-3_15DOI Listing
April 2012

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis.

Diabetes 2012 Feb 30;61(2):513-23. Epub 2011 Dec 30.

Institute of Pharmacology, Department of Endocrinology, Diabetes and Nutrition, Charité Medical University, the Center for Cardiovascular Research, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db11-0313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266407PMC
February 2012

High-dose treatment with telmisartan induces monocytic peroxisome proliferator-activated receptor-γ target genes in patients with the metabolic syndrome.

Hypertension 2011 Oct 29;58(4):725-32. Epub 2011 Aug 29.

Center for Cardiovascular Research, Institute of Pharmacology, Outpatient Clinic, Charité Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.173542DOI Listing
October 2011

Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.

Am J Physiol Heart Circ Physiol 2011 Jul 8;301(1):H115-22. Epub 2011 Apr 8.

Center for Cardiovascular Research (CCR Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.01222.2010DOI Listing
July 2011

Estrogen receptor-beta signals left ventricular hypertrophy sex differences in normotensive deoxycorticosterone acetate-salt mice.

Hypertension 2011 Mar 7;57(3):648-54. Epub 2011 Feb 7.

Department of Nephrology and Intensive Care Medicine Campus Virchow-Klinikum, Center forCardiovascular Research Medical Faculty, Charite´ Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.166157DOI Listing
March 2011

Role of the adipocyte-specific NF-κB activity in the regulation of IP-10 and T cell migration.

Am J Physiol Endocrinol Metab 2011 Feb 9;300(2):E304-11. Epub 2010 Nov 9.

Else Kröner-Fresenius-Centre for Nutritional Medicine, Freising, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.00143.2010DOI Listing
February 2011

Metabolic impact of estrogen signalling through ERalpha and ERbeta.

J Steroid Biochem Mol Biol 2010 Oct 3;122(1-3):74-81. Epub 2010 Jul 3.

Center for Cardiovascular Research (CCR), Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsbmb.2010.06.012DOI Listing
October 2010

PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.

Cardiovasc Diabetol 2010 Oct 18;9:64. Epub 2010 Oct 18.

Center for Cardiovascular Research, Institute of Pharmacology Charité-Universitätsmedizin Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2840-9-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984486PMC
October 2010

Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension.

Diabetes Res Clin Pract 2010 Sep;89(3):209-15

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diabres.2010.04.018DOI Listing
September 2010

Impact of HDL on adipose tissue metabolism and adiponectin expression.

Atherosclerosis 2010 Jun 1;210(2):438-44. Epub 2010 Feb 1.

Charité, University-Medicine Berlin, Campus Benjamin Franklin, Department of Cardiology, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2010.01.001DOI Listing
June 2010

Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation.

Hypertension 2009 Oct 17;54(4):738-43. Epub 2009 Aug 17.

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Strasse 3-4, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.132886DOI Listing
October 2009

Estrogen receptor alpha supports cardiomyocytes indirectly through post-infarct cardiac c-kit+ cells.

J Mol Cell Cardiol 2009 Jul 31;47(1):66-75. Epub 2009 Mar 31.

Center for Cardiovascular Research (CCR) and Institute of Pharmacology, Charité - Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yjmcc.2009.03.014DOI Listing
July 2009

Characterization of new PPARgamma agonists: benzimidazole derivatives - the importance of position 2.

ChemMedChem 2009 Jul;4(7):1136-42

Institute of Pharmacy, Freie Universität Berlin, Koenigin-Luise Strasse 2+4, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cmdc.200900067
Publisher Site
http://dx.doi.org/10.1002/cmdc.200900067DOI Listing
July 2009

ONTARGET, TRANSCEND, and PRoFESS: new-onset diabetes, atrial fibrillation, and left ventricular hypertrophy.

Authors:
Ulrich Kintscher

J Hypertens Suppl 2009 Jun;27(2):S36-9

Center for Cardiovascular Research (CCR), Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
https://insights.ovid.com/crossref?an=00004872-200906002-000
Publisher Site
http://dx.doi.org/10.1097/01.hjh.0000354519.67451.96DOI Listing
June 2009

INT-131, a PPARgamma agonist for the treatment of type 2 diabetes.

Curr Opin Investig Drugs 2009 Apr;10(4):381-7

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin Hessische Strasse 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
April 2009

Characterization of new PPARgamma agonists: analysis of telmisartan's structural components.

ChemMedChem 2009 Mar;4(3):445-56

Institute of Pharmacy, Freie Universität of Berlin, Koenigin-Luise Strasse 2+4, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cmdc.200800285DOI Listing
March 2009

Inhibiting angiotensin type 1 receptors as a target for diabetes.

Expert Opin Ther Targets 2008 Oct;12(10):1257-63

Charité-Universitätsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Hessische Street, 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.12.10.1257 DOI Listing
October 2008

Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren.

J Hypertens 2008 Sep;26(9):1787-94

Center for Cardiovascular Research (CCR)/Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Strasse 3-4, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0b013e3283060f2eDOI Listing
September 2008

The cardiometabolic drug rimonabant: after 2 years of RIO-Europe and STRADIVARIUS.

Authors:
Ulrich Kintscher

Eur Heart J 2008 Jul 13;29(14):1709-10. Epub 2008 Jun 13.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/eurheartj/ehn255DOI Listing
July 2008

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.

Diabetes 2008 May 9;57(5):1405-13. Epub 2008 Jan 9.

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db07-0839DOI Listing
May 2008

Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain.

Brain Res 2008 May 4;1208:225-33. Epub 2008 Mar 4.

Center for Cardiovascular Research/Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2008.02.032DOI Listing
May 2008

Insulin facilitates monocyte migration: a possible link to tissue inflammation in insulin-resistance.

Biochem Biophys Res Commun 2008 Jan 20;365(3):503-8. Epub 2007 Nov 20.

Center for Cardiovascular Research, Institute of Pharmacology, Charité Campus Mitte, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, D-10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2007.11.006DOI Listing
January 2008

Does adiponectin resistance exist in chronic heart failure?

Authors:
Ulrich Kintscher

Eur Heart J 2007 Jul 25;28(14):1676-7. Epub 2007 Jun 25.

Center for Cardiovascular Research (CCR), Institute of Pharmacology, Charité - Universitätsmedizin Berlin, Hessische Str 3-4, Berlin, Germany.

View Article

Download full-text PDF

Source
https://academic.oup.com/eurheartj/article-lookup/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/eurheartj/ehm233DOI Listing
July 2007

The endothelium and vascular inflammation in diabetes.

Diab Vasc Dis Res 2007 Jun;4(2):84-8

Center for Cardiovascular Research, Charité-Universitaetsmedizin Berlin, Hessische Strasse 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3132/dvdr.2007.025DOI Listing
June 2007

Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.

Circulation 2007 Apr 2;115(15):1991-8. Epub 2007 Apr 2.

Department of Medicine, Outpatient Clinic, CCM, Charité-Universitätsmedizin Berlin, Luisenstrasse 11-13, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.106.625400DOI Listing
April 2007

Endothelial dysfunction and its role in diabetic vascular disease.

Endocrinol Metab Clin North Am 2006 Sep;35(3):551-60, viii-ix

Center for Cardiovascular Research, Institute for Pharmacology, Charité Berlin, Hessische Strasse 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S088985290600046
Publisher Site
http://dx.doi.org/10.1016/j.ecl.2006.06.006DOI Listing
September 2006

Cardiac PPARalpha expression in patients with dilated cardiomyopathy.

Eur J Heart Fail 2006 May 22;8(3):290-4. Epub 2005 Nov 22.

Center for Cardiovascular Research, CCR, Institute of Pharmacology and Toxicology, Charité-Universitätsmedizin Berlin, CCM, Hessischestr. 3-4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejheart.2005.09.003DOI Listing
May 2006

Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites.

Hypertension 2006 Mar 19;47(3):586-9. Epub 2005 Dec 19.

Center for Cardiovascular Research, Institute of Pharmacology and Toxicology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://hyper.ahajournals.org/content/47/3/586.full.pdf
Web Search
http://hyper.ahajournals.org/cgi/doi/10.1161/01.HYP.00001969
Publisher Site
http://dx.doi.org/10.1161/01.HYP.0000196946.79674.8bDOI Listing
March 2006

The metabolic syndrome: cluster with a self-fulfilling loop?

J Hypertens 2006 Feb;24(2):257-8

Center for Cardiovascular Research, Institute of Pharmacology and Toxicology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.hjh.0000202813.79964.4aDOI Listing
February 2006

[Olmesartan after experimental myocardial infarct compared with ramipril: organ protective effect].

Authors:
Ulrich Kintscher

Krankenpfl J 2005 ;43(4-6):112

Center for Cardiovascular Research, Institut für Pharmakologie und Toxikologie, Campus Charité Mitte, HessischeStrasse 3-4, 10115 Berlin.

View Article

Download full-text PDF

Source
January 2006

Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity.

Diabetes 2005 Dec;54(12):3442-52

Center for Cardiovascular Research, Institute of Pharmacology and Toxicology, Charité Campus Mitte Charité-Universitätsmedizin Berlin, Hessische Str., 3-4 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://diabetes.diabetesjournals.org/content/diabetes/54/12/
Web Search
http://dx.doi.org/10.2337/diabetes.54.12.3442DOI Listing
December 2005

Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.

J Neurochem 2005 Sep 30;94(5):1395-401. Epub 2005 Jun 30.

Institute of Pharmacology, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts-University of Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1471-4159.2005.03275.xDOI Listing
September 2005

Does the AT2-receptor mediate anti-atherosclerotic actions?

J Hypertens 2005 Aug;23(8):1469-70

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.hjh.0000174611.49274.1eDOI Listing
August 2005

PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin.

Hypertension 2005 Jul 6;46(1):137-43. Epub 2005 Jun 6.

Center for Cardiovascular Research, Institut für Pharmakologie und Toxikologie, Charité Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany. .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.HYP.0000168046.19884.6aDOI Listing
July 2005

PPARgamma-mediated insulin sensitization: the importance of fat versus muscle.

Am J Physiol Endocrinol Metab 2005 Feb;288(2):E287-91

Center for Cardiovascular Research, Institut für Pharmakologie und Toxikologie, Campus Charité-Mitte, Charité-Universitätsmedizin Berlin, Hessische Strasse 3/4, 10115 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.00440.2004DOI Listing
February 2005

Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.

Circulation 2004 May 26;109(17):2054-7. Epub 2004 Apr 26.

Center for Cardiovascular Research, Institut für Pharmakologie und Toxikologie, Campus Charité-Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.CIR.0000127955.36250.65DOI Listing
May 2004

Angiotensin II, PPAR-gamma and atherosclerosis.

Front Biosci 2004 Jan 1;9:359-69. Epub 2004 Jan 1.

Institute of Pharmacology and Toxicology, Charite Hospital, Humboldt-University Berlin, D-10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2741/1225DOI Listing
January 2004