Publications by authors named "Ulrich Göbel"

73Publications

Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury.

Authors:
Ulrich Goebel Stefanie Scheid Sashko Spassov Nils Schallner Jakob Wollborn Hartmut Buerkle Felix Ulbrich

Neural Regen Res 2021 Jan;16(1):192-198

Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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January 2021

Early Postoperative Use of Diuretics After Kidney Transplantation Showed Increase in Delayed Graft Function.

Authors:
Wolfgang Baar Kai Kaufmann Kai Silbach Bernd Jaenigen Przemyslaw Pisarski Ulrich Goebel Johannes Kalbhenn Sebastian Heinrich Julian Knoerlein

Prog Transplant 2020 06 3;30(2):95-102. Epub 2020 Apr 3.

Faculty of Medicine, Department of Anesthesiology and Critical Care, Medical Center, University of Freiburg, Breisgau, Germany.

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June 2020

Carbon Monoxide Exerts Functional Neuroprotection After Cardiac Arrest Using Extracorporeal Resuscitation in Pigs.

Authors:
Jakob Wollborn Christoph Steiger Soroush Doostkam Nils Schallner Nils Schroeter Fabian A Kari Lorenz Meinel Hartmut Buerkle Martin A Schick Ulrich Goebel

Crit Care Med 2020 Apr;48(4):e299-e307

Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Freiburg, Germany.

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April 2020

LMA Gastro™ airway is feasible during upper gastrointestinal interventional endoscopic procedures in high risk patients: a single-center observational study.

Authors:
Axel Schmutz Thomas Loeffler Arthur Schmidt Ulrich Goebel

BMC Anesthesiol 2020 02 8;20(1):40. Epub 2020 Feb 8.

Department of Anesthesiology and Critical Care, Faculty of Medicine, Medical Center - University of Freiburg, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg im Breisgau, Germany.

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February 2020

Carbon monoxide in intensive care medicine-time to start the therapeutic application?!

Authors:
Ulrich Goebel Jakob Wollborn

Intensive Care Med Exp 2020 Jan 9;8(1). Epub 2020 Jan 9.

Department of Anaesthesiology and Critical Care, Medical Centre - University of Freiburg, Faculty of Medicine, Freiburg im Breisgau, Germany.

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January 2020

The Reproducibility of the Point of Care Microcirculation (POEM) Score When Used to Assess Critically Ill Patients: A Multicenter Prospective Observational Study.

Authors:
James C Watchorn Hithem Fargaly Muhammad Gilani Jordan Assadi Andrew R Deitchman David N Naumann Jakob Wollborn Ulrich Goebel Michael T McCurdy Sam D Hutchings

Shock 2020 07;54(1):15-20

Critical Care, King's College Hospital, London, UK.

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July 2020

Extracorporeal resuscitation with carbon monoxide improves renal function by targeting inflammatory pathways in cardiac arrest in pigs.

Authors:
Jakob Wollborn Bjoern Schlueter Christoph Steiger Cornelius Hermann Christian Wunder Johannes Schmidt Patric Diel Lorenz Meinel Hartmut Buerkle Ulrich Goebel Martin A Schick

Am J Physiol Renal Physiol 2019 12 4;317(6):F1572-F1581. Epub 2019 Sep 4.

Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, Freiburg, Germany.

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December 2019

Epidural analgesia and avoidance of blood transfusion are associated with reduced mortality in patients with postoperative pulmonary complications following thoracotomic esophagectomy: a retrospective cohort study of 335 patients.

Authors:
Kai B Kaufmann Wolfgang Baar Torben Glatz Jens Hoeppner Hartmut Buerkle Ulrich Goebel Sebastian Heinrich

BMC Anesthesiol 2019 08 22;19(1):162. Epub 2019 Aug 22.

Department of Anesthesiology and Critical Care Medicine, University of Freiburg, - University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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August 2019

Lower rate of delayed graft function is observed when epidural analgesia for living donor nephrectomy is administered.

Authors:
Wolfgang Baar Ulrich Goebel Hartmut Buerkle Bernd Jaenigen Kai Kaufmann Sebastian Heinrich

BMC Anesthesiol 2019 03 18;19(1):38. Epub 2019 Mar 18.

Department of Anesthesiology and Critical Care, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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March 2019

Carbon monoxide improves haemodynamics during extracorporeal resuscitation in pigs.

Authors:
Jakob Wollborn Christoph Steiger Eva Ruetten Christoph Benk Fabian A Kari Christian Wunder Lorenz Meinel Hartmut Buerkle Martin A Schick Ulrich Goebel

Cardiovasc Res 2020 01;116(1):158-170

Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.

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January 2020

Phosphodiesterase-4 inhibition reduces ECLS-induced vascular permeability and improves microcirculation in a rodent model of extracorporeal resuscitation.

Authors:
Jakob Wollborn Svenja Siemering Christoph Steiger Hartmut Buerkle Ulrich Goebel Martin A Schick

Am J Physiol Heart Circ Physiol 2019 03 25;316(3):H751-H761. Epub 2019 Jan 25.

Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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March 2019

Peak airway pressure is lower during pressure-controlled than during manual facemask ventilation for induction of anesthesia in pediatric patients-a randomized, clinical crossover trial.

Authors:
Ulrich Goebel Stefan Schumann Steffen Wirth

J Anesth 2019 02 12;33(1):33-39. Epub 2018 Nov 12.

Department of Anesthesiology and Critical Care, Medical Center, University of Freiburg, Freiburg, Germany.

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February 2019

Somatosensory and transcranial motor evoked potential monitoring in a porcine model for experimental procedures.

Authors:
Sven Maier Ulrich Goebel Sonja Krause Christoph Benk Martin A Schick Hartmut Buerkle Friedhelm Beyersdorf Fabian A Kari Jakob Wollborn

PLoS One 2018 8;13(10):e0205410. Epub 2018 Oct 8.

Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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March 2019

Dorsal recruitment with flow-controlled expiration (FLEX): an experimental study in mechanically ventilated lung-healthy and lung-injured pigs.

Authors:
Silke Borgmann Johannes Schmidt Ulrich Goebel Joerg Haberstroh Josef Guttmann Stefan Schumann

Crit Care 2018 09 29;22(1):245. Epub 2018 Sep 29.

Department of Anesthesiology and Critical Care, Medical Center, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

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September 2018

Perioperative cytokine profile during lung surgery predicts patients at risk for postoperative complications-A prospective, clinical study.

Authors:
Kai B Kaufmann Sebastian Heinrich Hans Felix Staehle Lioudmila Bogatyreva Hartmut Buerkle Ulrich Goebel

PLoS One 2018 3;13(7):e0199807. Epub 2018 Jul 3.

Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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January 2019

Evaluation of hemodynamic goal-directed therapy to reduce the incidence of bone cement implantation syndrome in patients undergoing cemented hip arthroplasty - a randomized parallel-arm trial.

Authors:
Kai B Kaufmann Wolfgang Baar Judith Rexer Thomas Loeffler Sebastian Heinrich Lukas Konstantinidis Hartmut Buerkle Ulrich Goebel

BMC Anesthesiol 2018 06 6;18(1):63. Epub 2018 Jun 6.

Department of Anaesthesiology and Critical Care, Medical Center - University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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June 2018

Overcoming safety challenges in CO therapy - Extracorporeal CO delivery under precise feedback control of systemic carboxyhemoglobin levels.

Authors:
Jakob Wollborn Cornelius Hermann Ulrich Goebel Benjamin Merget Christian Wunder Sven Maier Thomas Schäfer Dominik Heuler Klaus Müller-Buschbaum Hartmut Buerkle Lorenz Meinel Martin A Schick Christoph Steiger

J Control Release 2018 06 12;279:336-344. Epub 2018 Apr 12.

Institute for Pharmacy and Food Chemistry, University of Würzburg, Germany. Electronic address:

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June 2018

Standardized model of porcine resuscitation using a custom-made resuscitation board results in optimal hemodynamic management.

Authors:
Jakob Wollborn Eva Ruetten Bjoern Schlueter Joerg Haberstroh Ulrich Goebel Martin A Schick

Am J Emerg Med 2018 10 31;36(10):1738-1744. Epub 2018 Jan 31.

Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Germany; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

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October 2018

Neuroprotection and neuroregeneration of retinal ganglion cells after intravitreal carbon monoxide release.

Authors:
Julia Stifter Felix Ulbrich Ulrich Goebel Daniel Böhringer Wolf Alexander Lagrèze Julia Biermann

PLoS One 2017 27;12(11):e0188444. Epub 2017 Nov 27.

Eye Center, Medical Center-University of Freiburg, Killianstrasse 5, Freiburg, Germany.

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December 2017

The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats' retinal ganglion cells after ischemia and reperfusion injury.

Authors:
Felix Ulbrich Claus Hagmann Hartmut Buerkle Carlos C Romao Nils Schallner Ulrich Goebel Julia Biermann

J Neuroinflammation 2017 06 27;14(1):130. Epub 2017 Jun 27.

Eye Center, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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June 2017

Application of the Novel Ventilation Mode FLow-Controlled EXpiration (FLEX): A Crossover Proof-of-Principle Study in Lung-Healthy Patients.

Authors:
Steffen Wirth Sebastian Springer Johannes Spaeth Silke Borgmann Ulrich Goebel Stefan Schumann

Anesth Analg 2017 10;125(4):1246-1252

From the Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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October 2017

Sedation vs Intubation for Patients With Acute Stroke Undergoing Thrombectomy.

Authors:
Hartmut Buerkle Ulrich Goebel

JAMA 2017 03;317(11):1177

Department of Anesthesiology and Critical Care, Medical Center, University of Freiburg, Freiburg, Germany.

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March 2017

An easy-to-build, low-budget point-of-care ultrasound simulator: from Linux to a web-based solution.

Authors:
Domagoj Damjanovic Ulrich Goebel Benedikt Fischer Martin Huth Hartmut Breger Hartmut Buerkle Axel Schmutz

Crit Ultrasound J 2017 Dec 16;9(1). Epub 2017 Feb 16.

Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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December 2017

The Molecular Pathway of Argon-Mediated Neuroprotection.

Authors:
Felix Ulbrich Ulrich Goebel

Int J Mol Sci 2016 Oct 31;17(11). Epub 2016 Oct 31.

Medical Center, Department of Anesthesiology and Critical Care, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106 Freiburg im Breisgau, Germany.

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October 2016

The CORM ALF-186 Mediates Anti-Apoptotic Signaling via an Activation of the p38 MAPK after Ischemia and Reperfusion Injury in Retinal Ganglion Cells.

Authors:
Felix Ulbrich Kai B Kaufmann Alexander Meske Wolf A Lagrèze Michael Augustynik Hartmut Buerkle Carlos C Ramao Julia Biermann Ulrich Goebel

PLoS One 2016 20;11(10):e0165182. Epub 2016 Oct 20.

Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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June 2017

Carbon monoxide treatment reduces microglial activation in the ischemic rat retina.

Authors:
Felix Ulbrich Ulrich Goebel Daniel Böhringer Petar Charalambous Wolf Alexander Lagrèze Julia Biermann

Graefes Arch Clin Exp Ophthalmol 2016 Oct 21;254(10):1967-1976. Epub 2016 Jul 21.

Eye Center, Medical Center, University of Freiburg, Killianstrasse 5, Freiburg im Breisgau, 79106, Germany.

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October 2016

Argon mediates protection by interleukin-8 suppression via a TLR2/TLR4/STAT3/NF-κB pathway in a model of apoptosis in neuroblastoma cells in vitro and following ischemia-reperfusion injury in rat retina in vivo.

Authors:
Felix Ulbrich Teresa Lerach Julia Biermann Kai B Kaufmann Wolf A Lagreze Hartmut Buerkle Torsten Loop Ulrich Goebel

J Neurochem 2016 09 30;138(6):859-73. Epub 2016 May 30.

Department of Anesthesiology and Critical Care, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.

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September 2016

The anti-inflammatory effects of E-α-(p-methoxyphenyl)-2',3,4,4'-tetramethoxychalcone are mediated via HO-1 induction.

Authors:
Kai B Kaufmann Monika Gothwal Nils Schallner Felix Ulbrich Hannelore Rücker Sabine Amslinger Ulrich Goebel

Int Immunopharmacol 2016 Jun 16;35:99-110. Epub 2016 Apr 16.

Department of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, Germany. Electronic address:

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June 2016

Propofol, but not ketamine or midazolam, exerts neuroprotection after ischaemic injury by inhibition of Toll-like receptor 4 and nuclear factor kappa-light-chain-enhancer of activated B-cell signalling: A combined in vitro and animal study.

Authors:
Felix Ulbrich Leonardo Eisert Hartmut Buerkle Ulrich Goebel Nils Schallner

Eur J Anaesthesiol 2016 Sep;33(9):670-80

From the Department of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, Freiburg, Germany.

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September 2016

Bacterial Contamination of the Anesthesia Workplace and Efficiency of Routine Cleaning Procedures: A Prospective Cohort Study.

Authors:
Ulrich Goebel Nicole Gebele Winfried Ebner Markus Dettenkofer Hartmut Bürkle Dieter Hauschke Sebastian Schulz-Stübner

Anesth Analg 2016 May;122(5):1444-7

From the *Department of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, Freiburg, Germany; †Institut für Umweltmedizin und Krankenhaushygiene am Universitätsklinikum Freiburg, Freiburg, Germany; ‡Institut für Krankenhaushygiene & Infektionsprävention, Gesundheitsverbund Landkreis Konstanz, Konstanz, Germany; §Institute of Medical Biometry and Medical Informatics, University of Freiburg, Freiburg, Germany; and ‖Deutsches Beratungszentrum für Hygiene (BZH GmbH), Freiburg, Germany.

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May 2016

Argon Mediates Anti-Apoptotic Signaling and Neuroprotection via Inhibition of Toll-Like Receptor 2 and 4.

Authors:
Felix Ulbrich Kai Kaufmann Martin Roesslein Franziska Wellner Volker Auwärter Jürgen Kempf Torsten Loop Hartmut Buerkle Ulrich Goebel

PLoS One 2015 1;10(12):e0143887. Epub 2015 Dec 1.

Department of Anesthesiology and Intensive Care Medicine, University Medical Center, Freiburg, Germany.

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June 2016

The Cytoprotective Effects of E-α-(4-Methoxyphenyl)-2',3,4,4'-Tetramethoxychalcone (E-α-p-OMe-C6H4-TMC)--A Novel and Non-Cytotoxic HO-1 Inducer.

Authors:
Kai B Kaufmann Nafisah Al-Rifai Felix Ulbrich Nils Schallner Hannelore Rücker Monika Enzinger Hermina Petkes Sebastian Pitzl Ulrich Goebel Sabine Amslinger

PLoS One 2015 13;10(11):e0142932. Epub 2015 Nov 13.

Institute of Organic Chemistry, University of Regensburg, Regensburg, Germany.

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June 2016

Argon: a novel therapeutic option to treat neuronal ischemia and reperfusion injuries?

Authors:
Felix Ulbrich Ulrich Goebel

Neural Regen Res 2015 Jul;10(7):1043-4

Department of Anesthesiology and Intensive Care Medicine, University Medical Center, Freiburg, Germany.

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July 2015

Thiopental protects human neuroblastoma cells from apoptotic cell death - Potential role of heat shock protein 70.

Authors:
Martin Roesslein Christian Froehlich Verena Miltenberger Felix Ulbrich Ulrich Goebel Torsten Loop

Life Sci 2015 Oct 18;139:40-5. Epub 2015 Aug 18.

Department of Anaesthesiology and Critical Care Medicine, University Medical Center, Freiburg, Germany.

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October 2015

Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial.

Authors:
Alexander Zarbock Christoph Schmidt Hugo Van Aken Carola Wempe Sven Martens Peter K Zahn Britta Wolf Ulrich Goebel Christian I Schwer Peter Rosenberger Helene Haeberle Dennis Görlich John A Kellum Melanie Meersch

JAMA 2015 Jun;313(21):2133-41

Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine, University Hospital Münster, Münster, Germany.

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June 2015

Neuroprotective effects of Argon are mediated via an ERK-1/2 dependent regulation of heme-oxygenase-1 in retinal ganglion cells.

Authors:
Felix Ulbrich Kai B Kaufmann Mark Coburn Wolf Alexander Lagrèze Martin Roesslein Julia Biermann Hartmut Buerkle Torsten Loop Ulrich Goebel

J Neurochem 2015 Aug 27;134(4):717-27. Epub 2015 Apr 27.

Department of Anesthesiology and Intensive Care Medicine, University Medical Center, Freiburg, Germany.

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August 2015

Comparison of airway management techniques for different access in a simulated motor vehicle entrapment scenario.

Authors:
Daniel Steinmann Thomas Ahne Christian Heringhaus Ulrich Goebel

Eur J Emerg Med 2016 Aug;23(4):279-285

aOccupational Medical ServicebDepartment of Anaesthesiology, University Medical Center Freiburg, Freiburg, GermanycDepartment of Emergency Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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August 2016

Argon inhalation attenuates retinal apoptosis after ischemia/reperfusion injury in a time- and dose-dependent manner in rats.

Authors:
Felix Ulbrich Nils Schallner Mark Coburn Torsten Loop Wolf Alexander Lagrèze Julia Biermann Ulrich Goebel

PLoS One 2014 23;9(12):e115984. Epub 2014 Dec 23.

Department of Anesthesiology and Intensive Care Medicine, University Medical Center, Freiburg, Germany.

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December 2015

Isoflurane but not sevoflurane or desflurane aggravates injury to neurons in vitro and in vivo via p75NTR-NF-ĸB activation.

Authors:
Nils Schallner Felix Ulbrich Helen Engelstaedter Julia Biermann Volker Auwaerter Torsten Loop Ulrich Goebel

Anesth Analg 2014 Dec;119(6):1429-41

From the *Department of Anesthesiology and Intensive Care Medicine, University Medical Center Freiburg, Freiburg, Germany; †Eye Center, Albert-Ludwigs-University of Freiburg, Freiburg, Germany; and ‡Institute of Forensic Medicine, University Medical Center, Freiburg, Germany.

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December 2014

Dobutamine mediates cytoprotection by induction of heat shock protein 70 in vitro.

Authors:
Martin Roesslein Christian Froehlich Frank Jans Tobias Piegeler Ulrich Goebel Torsten Loop

Life Sci 2014 Mar 18;98(2):88-95. Epub 2014 Jan 18.

Dept. of Anaesthesiology and Critical Care Medicine, University Medical Center, Freiburg, Germany.

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March 2014

Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway.

Authors:
Nils Schallner Carlos C Romão Julia Biermann Wolf A Lagrèze Leo E Otterbein Hartmut Buerkle Torsten Loop Ulrich Goebel

PLoS One 2013 8;8(4):e60672. Epub 2013 Apr 8.

Department of Anesthesiology, Division for Experimental Anesthesiology, University Medical Center Freiburg, Germany.

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November 2013

The perioperative use of nitrous oxide: renaissance of an old gas or funeral of an ancient relict?

Authors:
Nils Schallner Ulrich Goebel

Curr Opin Anaesthesiol 2013 Jun;26(3):354-60

Department of Anesthesiology and Critical Care Medicine, University Medical Center, Freiburg, Germany.

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June 2013

Postconditioning with inhaled carbon monoxide counteracts apoptosis and neuroinflammation in the ischemic rat retina.

Authors:
Nils Schallner Matthias Fuchs Christian I Schwer Torsten Loop Hartmut Buerkle Wolf Alexander Lagrèze Christian van Oterendorp Julia Biermann Ulrich Goebel

PLoS One 2012 28;7(9):e46479. Epub 2012 Sep 28.

Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany.

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February 2013

Cytoprotection by inhaled carbon monoxide before cardiopulmonary bypass in preclinical models.

Authors:
Torsten Loop Christian Schlensak Ulrich Goebel

Curr Pharm Biotechnol 2012 May;13(6):797-802

Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg, Germany.

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May 2012

Hepatic steatosis prevents heme oxygenase-1 induction by isoflurane in the rat liver.

Authors:
Patrick Stoll Christian I Schwer Ulrich Goebel Hartmut Buerkle Alexander Hoetzel Rene Schmidt

World J Gastroenterol 2011 Oct;17(37):4184-90

Department of Anesthesiology and Critical Care Medicine, Freiburg University Medical Center, D-79106 Freiburg, Germany.

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October 2011

Effects of hydrogen sulfide on rat pancreatic stellate cells.

Authors:
Christian I Schwer Patrick Stoll Ulrich Goebel Hartmut Buerkle Alexander Hoetzel Rene Schmidt

Pancreas 2012 Jan;41(1):74-83

Department of Anesthesiology and Critical Care Medicine, University Medical Center, Freiburg, Germany.

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January 2012

p38β-regulated induction of the heat shock response by carbon monoxide releasing molecule CORM-2 mediates cytoprotection in lung cells in vitro.

Authors:
Nils Schallner Sven Schwemmers Christian I Schwer Christian Froehlich Patrick Stoll Matjaz Humar Heike L Pahl Alexander Hoetzel Torsten Loop Ulrich Goebel

Eur J Pharmacol 2011 Nov 8;670(1):58-66. Epub 2011 Sep 8.

Department of Anesthesiology and Critical Care Medicine, University Medical Center, Freiburg, Germany.

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November 2011

Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury.

Authors:
Julia Biermann Wolf A Lagrèze Nils Schallner Christian I Schwer Ulrich Goebel

Mol Vis 2011 7;17:1275-86. Epub 2011 May 7.

University Eye Hospital Freiburg, Freiburg, Germany.

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September 2011

Postconditioning of the lungs with inhaled carbon monoxide after cardiopulmonary bypass in pigs.

Authors:
Ulrich Goebel Matthias Siepe Christian I Schwer David Schibilsky Kerstin Brehm Hans-Joachim Priebe Christian Schlensak Torsten Loop

Anesth Analg 2011 Feb 14;112(2):282-91. Epub 2010 Dec 14.

Department of Anesthesiology, University Medical Centre, Hugstetterstrasse 55, D-79106 Freiburg im Breisgau, Germany.

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February 2011

Re: Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.

Authors:
David Schibilsky Friedhelm Beyersdorf Ulrich Goebel

J Heart Lung Transplant 2010 Dec 19;29(12):1442; discussion 1442-3. Epub 2010 Sep 19.

Department of Cardiovascular Surgery, University Medical Center, Freiburg, Germany.

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December 2010

Up-regulation of heme oxygenase-1 by sevoflurane is not dependent on Kupffer cells and associates with ERK1/2 and AP-1 activation in the rat liver.

Authors:
Christian Ingo Schwer Patrick Stoll Urs Pietsch Philipp Stein Jessica Laqua Ulrich Goebel Alexander Hoetzel Rene Schmidt

Int J Biochem Cell Biol 2010 Nov 18;42(11):1876-83. Epub 2010 Aug 18.

Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg, Freiburg, Germany.

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November 2010

Inhaled carbon monoxide prevents acute kidney injury in pigs after cardiopulmonary bypass by inducing a heat shock response.

Authors:
Ulrich Goebel Matthias Siepe Christian I Schwer David Schibilsky Katharina Foerster Jens Neumann Thorsten Wiech Hans-Joachim Priebe Christian Schlensak Torsten Loop

Anesth Analg 2010 Jul 2;111(1):29-37. Epub 2010 Jun 2.

Department of Anesthesiology and Critical Care Medicine, University Medical Centre, Hugstetterstrasse 55, D-79106 Freiburg im Breisgau, Germany.

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July 2010

Preconditioning with inhalative carbon monoxide protects rat retinal ganglion cells from ischemia/reperfusion injury.

Authors:
Julia Biermann Wolf A Lagrèze Cornelia Dimitriu Christian Stoykow Ulrich Goebel

Invest Ophthalmol Vis Sci 2010 Jul 24;51(7):3784-91. Epub 2010 Feb 24.

University Eye Hospital Freiburg, University Medical Center, Killianstrasse 5, 79106 Freiburg, Germany.

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July 2010

Low pulmonary artery flush perfusion pressure combined with high positive end-expiratory pressure reduces oedema formation in isolated porcine lungs.

Authors:
Stefan Schumann Andreas Kirschbaum Stephan J Schliessmann Giskard Wagner Ulrich Goebel Hans-Joachim Priebe Josef Guttmann

Physiol Meas 2010 Feb 20;31(2):261-72. Epub 2010 Jan 20.

Department of Anaesthesiology, Division of Experimental Anaesthesiology, University Medical Centre Freiburg, Germany.

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February 2010

Carbon monoxide releasing molecule-2 inhibits pancreatic stellate cell proliferation by activating p38 mitogen-activated protein kinase/heme oxygenase-1 signaling.

Authors:
Christian I Schwer Manuel Mutschler Patrick Stoll Ulrich Goebel Matjaz Humar Alexander Hoetzel Rene Schmidt

Mol Pharmacol 2010 Apr 6;77(4):660-9. Epub 2010 Jan 6.

Department of Anesthesiology, University Medical Center, Hugstetter Strasse 55, D-79106 Freiburg, Germany.

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April 2010

Krüppel-like factor 15 regulates BMPER in endothelial cells.

Authors:
Thomas Helbing Franziska Volkmar Ulrich Goebel Jennifer Heinke Philipp Diehl Heike L Pahl Christoph Bode Cam Patterson Martin Moser

Cardiovasc Res 2010 Feb 17;85(3):551-9. Epub 2009 Sep 17.

Department of Cardiology, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.

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February 2010

Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells.

Authors:
Julia Biermann Philippe Grieshaber Ulrich Goebel Gottfried Martin Solon Thanos Simone Di Giovanni Wolf Alexander Lagrèze

Invest Ophthalmol Vis Sci 2010 Jan 23;51(1):526-34. Epub 2009 Jul 23.

University Eye Hospital Freiburg, Freiburg im Breisgau, Germany.

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January 2010

Carbon monoxide prevents ventilator-induced lung injury via caveolin-1.

Authors:
Alexander Hoetzel Rene Schmidt Simone Vallbracht Ulrich Goebel Tamas Dolinay Hong Pyo Kim Emeka Ifedigbo Stefan W Ryter Augustine M K Choi

Crit Care Med 2009 May;37(5):1708-15

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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May 2009

The CD70/CD27 pathway is critical for stimulation of an effective cytotoxic T cell response against B cell precursor acute lymphoblastic leukemia.

Authors:
Ludmila Glouchkova Birgit Ackermann Andree Zibert Roland Meisel Meinolf Siepermann Gritta E Janka-Schaub Ulrich Goebel Anja Troeger Dagmar Dilloo

J Immunol 2009 Jan;182(1):718-25

Clinic for Pediatric Oncology, Hematology, and Clinical Immunology, Heinrich Heine University of Duesseldorf, Duesseldorf, Germany.

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January 2009

Heterocyclic thioureylenes protect from calcium-dependent neuronal cell death.

Authors:
Matjaz Humar Christine Graetz Martin Roesslein Ulrich Goebel Klaus K Geiger Bernd Heimrich Benedikt H J Pannen

Mol Pharmacol 2009 Mar 22;75(3):667-76. Epub 2008 Dec 22.

Department of Anesthesiology and Critical Care Medicine, Center for Clinical Research, University Hospital Freiburg, Freiburg, Germany.

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March 2009

eComment: Carbon monoxide and its vasodilatative properties: another good reason for clinical implication.

Authors:
Ulrich Goebel Matthias Siepe

Interact Cardiovasc Thorac Surg 2008 Dec;7(6):962-3

Department of Anesthesiology and Critical Care Medicine, Freiburg, Germany.

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December 2008

Reduced pulmonary inflammatory response during cardiopulmonary bypass: effects of combined pulmonary perfusion and carbon monoxide inhalation.

Authors:
Ulrich Goebel Matthias Siepe Anne Mecklenburg Torsten Doenst Friedhelm Beyersdorf Torsten Loop Christian Schlensak

Eur J Cardiothorac Surg 2008 Dec 1;34(6):1165-72. Epub 2008 Oct 1.

Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg, Freiburg, Germany.

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December 2008

Heme oxygenase-1 inhibits the proliferation of pancreatic stellate cells by repression of the extracellular signal-regulated kinase1/2 pathway.

Authors:
Christian I Schwer Aida M Guerrero Matjaz Humar Martin Roesslein Ulrich Goebel Patrick Stoll Klaus K Geiger Benedikt H J Pannen Alexander Hoetzel Rene Schmidt

J Pharmacol Exp Ther 2008 Dec 10;327(3):863-71. Epub 2008 Sep 10.

Department of Anesthesiology, University Medical Center, Freiburg, Germany.

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December 2008

Pulsatile pulmonary perfusion during cardiopulmonary bypass reduces the pulmonary inflammatory response.

Authors:
Matthias Siepe Ulrich Goebel Anne Mecklenburg Torsten Doenst Christoph Benk Philipp Stein Friedhelm Beyersdorf Torsten Loop Christian Schlensak

Ann Thorac Surg 2008 Jul;86(1):115-22

Department of Cardiovascular Surgery, University Medical Center, Freiburg, Germany.

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July 2008

High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95.

Authors:
Anja Troeger Ludmila Glouchkova Birgit Ackermann Gabriele Escherich Roland Meisel Helmut Hanenberg Monique L den Boer Rob Pieters Gritta E Janka-Schaub Ulrich Goebel Hans-Juergen Laws Dagmar Dilloo

Blood 2008 Aug 13;112(4):1028-34. Epub 2008 Jun 13.

Clinic for Pediatric Oncology, Heinrich Heine University of Duesseldorf, Duesseldorf, Germany.

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August 2008

Carbon monoxide inhalation reduces pulmonary inflammatory response during cardiopulmonary bypass in pigs.

Authors:
Ulrich Goebel Matthias Siepe Anne Mecklenburg Phillip Stein Martin Roesslein Christian I Schwer Rene Schmidt Torsten Doenst Klaus K Geiger Heike L Pahl Christian Schlensak Torsten Loop

Anesthesiology 2008 Jun;108(6):1025-36

Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg, Germany.

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June 2008

Sevoflurane-mediated activation of p38-mitogen-activated stresskinase is independent of apoptosis in Jurkat T-cells.

Authors:
Martin Roesslein Michael Frick Volker Auwaerter Matjaz Humar Ulrich Goebel Christian Schwer Klaus K Geiger Heike L Pahl Benedikt H J Pannen Torsten Loop

Anesth Analg 2008 Apr;106(4):1150-60, table of contents

Department of Anesthesiology and Critical Care Medicine, University Hospital, Freiburg, Germany.

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April 2008

Thiopental protects human T lymphocytes from apoptosis in vitro via the expression of heat shock protein 70.

Authors:
Martin Roesslein David Schibilsky Laurent Muller Ulrich Goebel Christian Schwer Matjaz Humar Rene Schmidt Klaus K Geiger Heike L Pahl Benedikt H J Pannen Torsten Loop

J Pharmacol Exp Ther 2008 Apr 24;325(1):217-25. Epub 2008 Jan 24.

Anaesthesiologische Universitaetsklinik, Hugstetterstrasse 55, D-79106 Freiburg, Germany.

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April 2008

Thionamides inhibit the transcription factor nuclear factor-kappaB by suppression of Rac1 and inhibitor of kappaB kinase alpha.

Authors:
Matjaz Humar Hannah Dohrmann Philipp Stein Nikolaos Andriopoulos Ulrich Goebel Martin Roesslein Rene Schmidt Christian I Schwer Torsten Loop Klaus K Geiger Heike L Pahl Benedikt H J Pannen

J Pharmacol Exp Ther 2008 Mar 30;324(3):1037-44. Epub 2007 Nov 30.

Center for Clinical Research, Breisacher Strasse 66, D-79106 Freiburg, Germany.

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March 2008

High nerve growth factor receptor (p75NTR) expression is a favourable prognostic factor in paediatric B cell precursor-acute lymphoblastic leukaemia.

Authors:
Anja Troeger Sonja Gudowius Gabriele Escherich Monique L den Boer Ludmila Glouchkova Birgit Ackermann Roland Meisel Hans-Juergen Laws Marketa Groeger Ruediger Wessalowski Reinhart Willers Jochen Harbott Rob Pieters Ulrich Goebel Gritta E Janka-Schaub Helmut Hanenberg Dagmar Dilloo

Br J Haematol 2007 Nov;139(3):450-7

Clinic for Paediatric Haematology, Oncology and Immunology, Heinrich Heine University, Duesseldorf, Germany.

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November 2007

Repression of T-cell function by thionamides is mediated by inhibition of the activator protein-1/nuclear factor of activated T-cells pathway and is associated with a common structure.

Authors:
Matjaz Humar Hannah Dohrmann Philipp Stein Nikolaos Andriopoulos Ulrich Goebel Bernd Heimrich Martin Roesslein Rene Schmidt Christian I Schwer Alexander Hoetzel Torsten Loop Heike L Pahl Klaus K Geiger Benedikt H J Pannen

Mol Pharmacol 2007 Dec 18;72(6):1647-56. Epub 2007 Sep 18.

Center for Clinical Research, Breisacher Strasse 66, D-79106 Freiburg, Germany.

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December 2007

Survivin and its prognostic significance in pediatric acute B-cell precursor lymphoblastic leukemia.

Authors:
Anja Troeger Meinolf Siepermann Gabriele Escherich Roland Meisel Reinhardt Willers Sonja Gudowius Thomas Moritz Hans-Juergen Laws Helmut Hanenberg Ulrich Goebel Gritta E Janka-Schaub Csaba Mahotka Dagmar Dilloo

Haematologica 2007 Aug 20;92(8):1043-50. Epub 2007 Jul 20.

Clinic for Pediatric Oncology, Hematology and Immunology, University of Duesseldorf, Duesseldorf, Germany.

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August 2007

Mesoblastic nephroma--a report from the Gesellschaft fur Pädiatrische Onkologie und Hämatologie (GPOH).

Authors:
Rhoikos Furtwaengler Harald Reinhard Ivo Leuschner Jens P Schenk Ulrich Goebel Alexander Claviez Andreas Kulozik Andreas Zoubek Dietrich von Schweinitz Norbert Graf

Cancer 2006 May;106(10):2275-83

Department of Pediatric Hematology and Oncology, Saarland University Hospital, Homburg/Saar, Germany.

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May 2006