Ulrich Beuers

Ulrich Beuers

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Ulrich Beuers

Publications by authors named "Ulrich Beuers"

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Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial.

Lancet Gastroenterol Hepatol 2019 Oct 10. Epub 2019 Oct 10.

Institut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEReHD), Barcelona, Spain; Liver Unit, Hospital Clínic De Barcelona, School of Medicine and Health Sciences University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(19)30320-6DOI Listing
October 2019

Fatigue in Primary Biliary Cholangitis: no Place for Rituximab.

Hepatology 2019 Aug 23. Epub 2019 Aug 23.

Department of Medicine II, University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1002/hep.30906DOI Listing
August 2019

Ursodeoxycholic acid in pregnancy ?

J Hepatol 2019 Aug 31. Epub 2019 Aug 31.

Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.08.020DOI Listing
August 2019

Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice.

J Hepatol 2019 Jul 29;71(1):153-162. Epub 2019 Mar 29.

Amsterdam University Medical Centers, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.03.021DOI Listing
July 2019

Effect of Plasmapheresis on Cholestatic Pruritus and Autotaxin Activity During Pregnancy.

Hepatology 2019 Jun 14;69(6):2707-2710. Epub 2019 Feb 14.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.1002/hep.30496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593664PMC
June 2019

Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis.

Sci Rep 2019 Jun 11;9(1):8450. Epub 2019 Jun 11.

Norwegian PSC Research Center, Department of transplantation medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1038/s41598-019-44762-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559994PMC
June 2019

Primary biliary cholangitis: A tale of epigenetically-induced secretory failure?

J Hepatol 2018 12 5;69(6):1371-1383. Epub 2018 Sep 5.

Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), Spain; Ikerbasque, Basque Foundation for Science, Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.08.020DOI Listing
December 2018

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Gut 2018 08 4;67(8):1517-1524. Epub 2017 Aug 4.

Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/gutjnl-2016-313598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797498PMC
August 2018

[The different forms of IgG4-related disease].

Ned Tijdschr Geneeskd 2018 08 16;162. Epub 2018 Aug 16.

Amsterdam UMC, locatie AMC, afd. Maag-, Darm- en Leverziekten.

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August 2018

Role of Bile Acids and the Biliary HCO Umbrella in the Pathogenesis of Primary Biliary Cholangitis.

Clin Liver Dis 2018 08 19;22(3):457-479. Epub 2018 May 19.

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2018.03.013DOI Listing
August 2018

Primary sclerosing cholangitis.

Lancet 2018 06 13;391(10139):2547-2559. Epub 2018 Feb 13.

Department of Hepatology, Newcastle upon Tyne Hospitals NHS Foundation Trust and Institute of Cellular Medicine, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1016/S0140-6736(18)30300-3DOI Listing
June 2018

Bioengineered bile ducts recapitulate key cholangiocyte functions.

Biofabrication 2018 06 12;10(3):034103. Epub 2018 Jun 12.

Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.

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http://stacks.iop.org/1758-5090/10/i=3/a=034103?key=crossref
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http://dx.doi.org/10.1088/1758-5090/aac8fdDOI Listing
June 2018

IgG4-Associated Cholangitis in Patients Resected for Presumed Perihilar Cholangiocarcinoma: a 30-Year Tertiary Care Experience.

Am J Gastroenterol 2018 05 16;113(5):765-772. Epub 2018 Mar 16.

Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands. Department of Gastroenterology & Hepatology and Tytgat institute for Liver and intestinal Research, Academic Medical Center, Amsterdam, The Netherlands. Department of Clinical immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, & Laboratory of Experimental Medicine, Academic Medical Center, Amsterdam, The Netherlands. Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands. These authors contributed equally: Eva Roos, Lowiek M. Hubers.

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http://dx.doi.org/10.1038/s41395-018-0036-5DOI Listing
May 2018

Clinical Reasoning: Accumulating endocrinopathies in a car salesman.

Neurology 2018 05;90(19):e1720-e1723

From the Departments of Neurology (L.W., M.C.B.) and Gastroenterology and Hepatology (U.B.), Academic Medical Center, University of Amsterdam; and Centre of Infection and Immunity Amsterdam (CINIMA) (M.C.B.), the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000005478DOI Listing
May 2018

Annexin A11 is targeted by IgG4 and IgG1 autoantibodies in IgG4-related disease.

Gut 2018 04 1;67(4):728-735. Epub 2017 Aug 1.

Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/gutjnl-2017-314548DOI Listing
April 2018

On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease.

Biochim Biophys Acta Mol Basis Dis 2018 04 4;1864(4 Pt B):1401-1409. Epub 2017 Aug 4.

Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.07.038DOI Listing
April 2018

Role of the bicarbonate-responsive soluble adenylyl cyclase in cholangiocyte apoptosis in primary biliary cholangitis; a new hypothesis.

Biochim Biophys Acta Mol Basis Dis 2018 04 28;1864(4 Pt B):1232-1239. Epub 2017 Sep 28.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.09.022DOI Listing
April 2018

Na -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice.

Hepatology 2018 Mar 24. Epub 2018 Mar 24.

Tytgat Institute for Liver and Intestinal Research and Department of Gastroenterology & Hepatology, Amsterdam Gastroenterology and Metabolism, AMC, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/hep.29888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175374PMC
March 2018

MR Spectroscopy-derived Proton Density Fat Fraction Is Superior to Controlled Attenuation Parameter for Detecting and Grading Hepatic Steatosis.

Radiology 2018 02 15;286(2):547-556. Epub 2017 Sep 15.

From the Departments of Radiology and Nuclear Medicine (J.H.R., A.J.N., J.S.), Vascular Medicine (L.P.S.), Pathology (J.V.), and Gastroenterology and Hepatology (U.B.), Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Slotervaartziekenhuis, Amsterdam, the Netherlands (A.D.); and Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands (S.D.K., B.C.B.); and King's College London, Division of Imaging Sciences & Biomedical Engineering, London, England (J.H.R.).

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http://dx.doi.org/10.1148/radiol.2017162931DOI Listing
February 2018

Knockout of the primary sclerosing cholangitis-risk gene Fut2 causes liver disease in mice.

Hepatology 2017 08 19;66(2):542-554. Epub 2017 Jun 19.

Department of Gastroenterology & Hepatology and Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/hep.29029
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http://dx.doi.org/10.1002/hep.29029DOI Listing
August 2017

IgG4-related disease of the biliary tract and pancreas: clinical and experimental advances.

Curr Opin Gastroenterol 2017 Jul;33(4):310-314

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/MOG.0000000000000362DOI Listing
July 2017

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.

Gastroenterology 2017 06 6;152(8):1975-1984.e8. Epub 2017 Mar 6.

Norwegian PSC Research Center and Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546611PMC
June 2017

The Emerging Role of Soluble Adenylyl Cyclase in Primary Biliary Cholangitis.

Dig Dis 2017 1;35(3):217-223. Epub 2017 Mar 1.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000450914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516404PMC
May 2017

Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo.

Sci Rep 2017 05 10;7(1):1646. Epub 2017 May 10.

Tytgat Institute for Liver and Intestinal Research & Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-01602-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431759PMC
May 2017

Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial.

Trials 2017 05 23;18(1):230. Epub 2017 May 23.

Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://trialsjournal.biomedcentral.com/articles/10.1186/s130
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http://dx.doi.org/10.1186/s13063-017-1966-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442649PMC
May 2017

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

Management of cholestatic disease in 2017.

Liver Int 2017 01;37 Suppl 1:123-129

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/liv.13306DOI Listing
January 2017

Alkaline phosphatase at diagnosis of primary sclerosing cholangitis and 1 year later: evaluation of prognostic value.

Liver Int 2016 12 4;36(12):1867-1875. Epub 2016 Apr 4.

Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/liv.13110DOI Listing
December 2016

Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion.

Cell Metab 2016 12 3;24(6):783-794. Epub 2016 Nov 3.

Department of Vascular Medicine, Academic Medical Center, Amsterdam 1105AZ, the Netherlands; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen 9713ZG, the Netherlands; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen 9713ZG, the Netherlands; Amsterdam Diabetes Research Center, Academic Medical Center, Amsterdam 1105AZ, the Netherlands; Groningen Center of Systems Biology, University Medical Center Groningen, Groningen 9713ZG, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.001DOI Listing
December 2016

Comparison of clinical MRI liver iron content measurements using signal intensity ratios, R and R .

Abdom Radiol (NY) 2016 11;41(11):2123-2131

Department of Radiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00261-016-0831-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059419PMC
November 2016

Ursodeoxycholic acid in advanced polycystic liver disease: A phase 2 multicenter randomized controlled trial.

J Hepatol 2016 09 17;65(3):601-7. Epub 2016 May 17.

Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.05.009DOI Listing
September 2016

Soluble Adenylyl Cyclase Regulates Bile Salt-Induced Apoptosis in Human Cholangiocytes.

Hepatology 2016 08 15;64(2):522-34. Epub 2016 Apr 15.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.28550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111777PMC
August 2016

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.

N Engl J Med 2016 Aug;375(7):631-43

From University Hospitals KU Leuven, Leuven, Belgium (F.N.); University of Bologna, Bologna (P.A., G.M.), Program for Autoimmune Liver Disease, International Center for Digestive Health, Department of Medicine and Surgery, University of Milan-Bicocca, Milan (P.I.), Humanitas Clinical and Research Center, Rozzano (P.I.), and University of Padua, Padua (A.F.) - all in Italy; Royal Prince Alfred Hospital, Camperdown, NSW, Australia (S.I.S.); University of California Davis Medical Center, Sacramento (C.B.), Scripps Clinic, La Jolla (P.J.P.), and Intercept Pharmaceuticals, San Diego (R.H.-R., T.M., S.S., R.P., L.M., M.P., D.S.) - all in California; Radboud University Nijmegen Medical Center, Nijmegen (J.P.H.D.), University of Amsterdam, Amsterdam (U.B.), University Medical Center Utrecht, Utrecht (K.J.E.), and University Medical Center Rotterdam, Rotterdam (B.H.) - all in the Netherlands; Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland (J.R.); Medical University of Vienna, Vienna (M.T.); Newcastle University Medical School, Newcastle upon Tyne (D.E.J.), and the Centre for Liver Research, NIHR Biomedical Research Unit, University of Birmingham, Birmingham (G.M.H.) - both in the United Kingdom; Liver Center Munich, Department of Medicine II, University of Munich, Munich, Germany (S.H.); Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond (V.L.), and the Liver Institute of Virginia, Newport News (M.S.) - all in Virginia; the Liver Unit, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas del Instituto de Salud Carlos III, Barcelona (V.V.); Centre Hospitalier de l'Université de Montréal-St. Luc, Montreal (C.V.); University Health Network Toronto Western Hospital, Toronto (H.S.); Arizona State University, Tempe (K.D.L.); Sahlgrenska Academy, University of Gothenburg,

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http://dx.doi.org/10.1056/NEJMoa1509840DOI Listing
August 2016

Preface.

Dig Dis 2015 7;33 Suppl 2. Epub 2015 Dec 7.

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http://dx.doi.org/10.1159/000441135DOI Listing
July 2016

A systematic approach to the management of cholestatic pruritus in primary biliary cirrhosis.

Frontline Gastroenterol 2016 Jul 26;7(3):158-166. Epub 2015 Aug 26.

Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1136/flgastro-2015-100618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369477PMC
July 2016

Serum Autotaxin Activity Correlates With Pruritus in Pediatric Cholestatic Disorders.

J Pediatr Gastroenterol Nutr 2016 Apr;62(4):530-5

*Department of Medicine I, Friedrich-Alexander-University of Erlangen, Erlangen, Germany †Tytgat Institute for Liver and Intestinal Research and Department of Hepatology & Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands ‡Pediatric Hepatology Unit and National Reference Centre for Biliary Atresia, DHU Hepatinov, CHU Bicêtre, Assistance Publique-Hôpitaux de Paris, University Paris-Sud, Paris, and Inserm UMR-S1174, Orsay, France §Department of Surgery, University of Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/MPG.0000000000001044DOI Listing
April 2016

A de novo mutation in KCNN3 associated with autosomal dominant idiopathic non-cirrhotic portal hypertension.

J Hepatol 2016 Apr 30;64(4):974-7. Epub 2015 Nov 30.

Department of Pediatric Genetics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.11.027DOI Listing
April 2016

Enteroendocrine cells are a potential source of serum autotaxin in men.

Biochim Biophys Acta 2016 04 14;1862(4):696-704. Epub 2016 Jan 14.

Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.01.012DOI Listing
April 2016

The Cholangiocyte Glycocalyx Stabilizes the 'Biliary HCO3 Umbrella': An Integrated Line of Defense against Toxic Bile Acids.

Dig Dis 2015 27;33(3):397-407. Epub 2015 May 27.

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000371864DOI Listing
March 2016

Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept Study.

Radiology 2016 Mar 7;278(3):782-91. Epub 2015 Sep 7.

From the Departments of Vascular Medicine (L.P.S., M.D.P., W.H.N., M.N., E.S.S.), Radiology (B.F.C., J.H.R., J.S., A.J.N.), Pathology (J.V.), and Gastroenterology & Hepatology (U.H.B.), Academic Medical Center, Meijbergdreef 9, Room F4-140, 1105 AZ Amsterdam, the Netherlands.

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http://dx.doi.org/10.1148/radiol.2015150952DOI Listing
March 2016

Chronic diarrhea because of villous atrophy unrelated to celiac disease.

Endoscopy 2015 17;47 Suppl 1 UCTN:E71-2. Epub 2015 Feb 17.

Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1055/s-0034-1391247DOI Listing
January 2016

Risk factors for primary sclerosing cholangitis.

Liver Int 2016 Jan 28;36(1):84-91. Epub 2015 Aug 28.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/liv.12894DOI Listing
January 2016

Disruption of HNF1α binding site causes inherited severe unconjugated hyperbilirubinemia.

J Hepatol 2015 Dec 26;63(6):1525-9. Epub 2015 Jul 26.

Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.07.027DOI Listing
December 2015

Applicability and prognostic value of histologic scoring systems in primary sclerosing cholangitis.

J Hepatol 2015 Nov 18;63(5):1212-9. Epub 2015 Jun 18.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.06.008DOI Listing
November 2015

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'.

Hepatology 2015 Nov 15;62(5):1620-2. Epub 2015 Sep 15.

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1002/hep.28140DOI Listing
November 2015

Changing nomenclature for PBC: from 'cirrhosis' to 'cholangitis'.

Gut 2015 Nov 14;64(11):1671-2. Epub 2015 Sep 14.

Service d'Hépatologie, Reference Center for Inflammatory Biliary Diseases, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1136/gutjnl-2015-310593DOI Listing
November 2015

Changing nomenclature for PBC: from 'cirrhosis' to 'cholangitis'.

Gastroenterology 2015 Nov 15;149(6):1627-9. Epub 2015 Sep 15.

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1053/j.gastro.2015.08.031DOI Listing
November 2015

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'.

J Hepatol 2015 Nov 15;63(5):1285-7. Epub 2015 Sep 15.

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2015.06.031DOI Listing
November 2015

Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'.

Clin Gastroenterol Hepatol 2015 Nov 18;13(11):1867-9. Epub 2015 Sep 18.

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1016/j.cgh.2015.08.025DOI Listing
November 2015

Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'.

Am J Gastroenterol 2015 Nov 29;110(11):1536-8. Epub 2015 Sep 29.

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1038/ajg.2015.312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679751PMC
November 2015

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'.

Dig Liver Dis 2015 Nov 26;47(11):924-6. Epub 2015 Sep 26.

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1016/j.dld.2015.08.007DOI Listing
November 2015

Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease.

J Hepatol 2015 Oct 1;63(4):952-61. Epub 2015 Jun 1.

Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastián, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, Instituto de Salud Carlos III), Spain; IKERBASQUE, Basque Foundation for Science, Spain; Division of Gene Therapy and Hepatology, CIMA of the University of Navarra, Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575914PMC
October 2015

The Long-Term Impact of Autoimmune Pancreatitis on Pancreatic Function, Quality of Life, and Life Expectancy.

Pancreas 2015 Oct;44(7):1065-71

From the*Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam; †Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, Amsterdam; Departments of ‡Public Health and §Pathology, Erasmus University Medical Center, Rotterdam; ∥Department of Pathology, Academic Medical Center Amsterdam, Amsterdam; ¶Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht; and #Department of Gastroenterology, Meander Medical Center, Amersfoort, The Netherlands.

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http://dx.doi.org/10.1097/MPA.0000000000000451DOI Listing
October 2015

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'.

Clin Res Hepatol Gastroenterol 2015 Oct;39(5):e57-9

Reference Center for Inflammatory Biliary Diseases, Service d'Hépatologie, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1016/j.clinre.2015.08.001DOI Listing
October 2015

A study of the relationship between serum bile acids and propranolol pharmacokinetics and pharmacodynamics in patients with liver cirrhosis and in healthy controls.

PLoS One 2014 6;9(6):e97885. Epub 2014 Jun 6.

Division of Clinical Pharmacology & Toxicology, University and University Hospital Basel, Basel, Switzerland; Department of Biomedicine, University of Basel, Basel, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097885PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048194PMC
August 2015

[A child with primary sclerosing cholangitis].

Ned Tijdschr Geneeskd 2015 ;159:A8312

Tergooi, afd. Kindergeneeskunde, Blaricum/Hilversum.

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August 2015

IgG4-associated cholangitis: a comprehensive review.

Clin Rev Allergy Immunol 2015 Jun;48(2-3):198-206

Department of Gastroenterology and Hepatology and Tytgat Institute of Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Meibergdreef 9, room G4-216, 1105 AZ, Amsterdam, The Netherlands.

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http://link.springer.com/10.1007/s12016-014-8430-2
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http://dx.doi.org/10.1007/s12016-014-8430-2DOI Listing
June 2015

Kinetics of primary bile acids in patients after proctocolectomy and ileal pouch-anal anastomosis.

Digestion 2014 13;90(1):27-32. Epub 2014 Aug 13.

Department of Gastroenterology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000362403DOI Listing
June 2015

Gene replacement therapy for genetic hepatocellular jaundice.

Clin Rev Allergy Immunol 2015 Jun;48(2-3):243-53

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, S1-172, University of Amsterdam, Meibergdreef 69, 1105BK, Amsterdam, The Netherlands,

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http://dx.doi.org/10.1007/s12016-014-8454-7DOI Listing
June 2015

Reply: To PMID 24807046.

Hepatology 2015 Jun 18;61(6):2115. Epub 2015 Apr 18.

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.27579DOI Listing
June 2015

Unmet challenges in immune-mediated hepatobiliary diseases.

Clin Rev Allergy Immunol 2015 Jun;48(2-3):127-31

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, P.O. Box 22600, 1100 DD, Amsterdam, The Netherlands,

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http://dx.doi.org/10.1007/s12016-015-8484-9DOI Listing
June 2015

How to Diagnose Immunoglobulin G4-Associated Cholangitis: The Jack-of-All-Trades in the Biliary Tract.

Viszeralmedizin 2015 Jun 9;31(3):185-8. Epub 2015 Jun 9.

Department of Gastroenterology & Hepatology and Tytgat Institute of Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000431028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569201PMC
June 2015

Biomarkers for disease progression of primary sclerosing cholangitis.

Curr Opin Gastroenterol 2015 May;31(3):239-46

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/MOG.0000000000000163DOI Listing
May 2015

Immunoglobulin G4-related cholangiopathy: clinical and experimental insights.

Curr Opin Gastroenterol 2015 May;31(3):252-7

aDepartment of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam bDepartment of Ophthalmology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOG.0000000000000170DOI Listing
May 2015

Characterization and treatment of persistent hepatocellular secretory failure.

Liver Int 2015 Apr 4;35(4):1478-88. Epub 2014 Jul 4.

Department of Gastroenterology & Hepatology and Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/liv.12603DOI Listing
April 2015

Analysis of aberrant pre-messenger RNA splicing resulting from mutations in ATP8B1 and efficient in vitro rescue by adapted U1 small nuclear RNA.

Hepatology 2015 Apr 23;61(4):1382-91. Epub 2015 Feb 23.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands; Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/hep.27620DOI Listing
April 2015

Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy.

J Hepatol 2015 Apr 5;62(4):897-904. Epub 2014 Nov 5.

Tytgat Institute for Liver and Intestinal Research and Department of Hepatology & Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.10.041DOI Listing
April 2015

New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond.

J Hepatol 2015 Apr;62(1 Suppl):S25-37

UPMC Université Paris 06, INSERM, UMR_S 938, Centre de Recherche Saint-Antoine, AP-HP, Hôpital Saint-Antoine, Service d'Hépatologie, F-75012 Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2015.02.023DOI Listing
April 2015

IgG4-associated cholangitis.

Dig Dis 2014 14;32(5):605-8. Epub 2014 Jul 14.

Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000360513DOI Listing
March 2015

Advances in pathogenesis and management of pruritus in cholestasis.

Dig Dis 2014 14;32(5):637-45. Epub 2014 Jul 14.

Department of Medicine 1, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1159/000360518DOI Listing
March 2015

[Risks of intrahepatic cholestasis of pregnancy].

Ned Tijdschr Geneeskd 2014 ;158:A7713

Academisch Medisch Centrum, Amsterdam.

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March 2015

Novel therapeutic targets in primary biliary cirrhosis.

Nat Rev Gastroenterol Hepatol 2015 Mar 3;12(3):147-58. Epub 2015 Feb 3.

Institute of Cellular Medicine, 3rd Floor William Leech Building, Medical School, Framlington Place, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1038/nrgastro.2015.12DOI Listing
March 2015

Lysophosphatidic acid and signaling in sensory neurons.

Biochim Biophys Acta 2015 Jan 16;1851(1):61-5. Epub 2014 Sep 16.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bbalip.2014.09.004DOI Listing
January 2015

Unmet clinical need in autoimmune liver diseases.

J Hepatol 2015 Jan 16;62(1):208-18. Epub 2014 Sep 16.

Liver Unit, Freeman Hospital, Newcastle-upon-Tyne, UK; UK-PBC Research Consortium, UK; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.09.010DOI Listing
January 2015