Publications by authors named "Tycho Baumann"

51Publications

The interval between frontline treatment and the second relapse (PFS2) predicts survival from the second relapse in follicular lymphoma patients.

Authors:
Pablo Mozas Marc Sorigué Alfredo Rivas-Delgado Andrea Rivero Juan G Correa Carlos Castillo Ferran Nadeu Alex Bataller Eva Giné Tycho Baumann Julio Delgado Neus Villamor Elias Campo Laura Magnano Juan-Manuel Sancho Armando López-Guillermo

Eur J Haematol 2020 Nov 28. Epub 2020 Nov 28.

Hematology Department, Hospital Clínic, Barcelona, Spain.

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November 2020

IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics.

Authors:
Ferran Nadeu Romina Royo Guillem Clot Martí Duran-Ferrer Alba Navarro Silvia Martin Junyan Lu Thorsten Zenz Tycho Stephan Baumann Pedro Jares Xose S Puente Iñaki Martin-Subero Julio Delgado Elías Campo

Blood 2020 Nov 19. Epub 2020 Nov 19.

Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.

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November 2020

Prognostic models in chronic lymphocytic leukemia patients receiving ibrutinib therapy: Results of a comparative performance analysis.

Authors:
Stefano Molica Tycho Baumann Diana Giannarelli

Eur J Haematol 2020 Nov 15. Epub 2020 Nov 15.

Biostatistic Unit, IRCCS Regina Elena, Roma, Italy.

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November 2020

Serum monoclonal component in chronic lymphocytic leukemia: baseline correlations and prognostic impact.

Authors:
Pablo Mozas Juan A Pineyroa Ferran Nadeu Laura Magnano Andrea Rivero Alfredo Rivas-Delgado Alex Bataller Aleix Fabregat Eva Gine Tycho Baumann Neus Villamor Juan Ignacio Arostegui Marta Aymerich Armando Lopez-Guillermo Elias Campo Julio Delgado

Haematologica 2020 Nov 5;Online ahead of print. Epub 2020 Nov 5.

Department of Hematology, Hospital Clínic, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid.

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November 2020

Mutational Landscape and Tumor Burden Assessed by Cell-free DNA in Diffuse Large B-Cell Lymphoma in a Population-Based Study.

Authors:
Alfredo Rivas-Delgado Ferran Nadeu Anna Enjuanes Sebastián Casanueva-Eliceiry Pablo Mozas Laura Magnano Natalia Castrejón de Anta Jordina Rovira Ivan Dlouhy Silvia Martín Miguel Osuna Sonia Rodríguez Marc Simó Magda Pinyol Tycho Baumann Silvia Beà Olga Balagué Julio Delgado Neus Villamor Xavier Setoain Elías Campo Eva Giné Armando López-Guillermo

Clin Cancer Res 2020 Oct 29. Epub 2020 Oct 29.

Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain.

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October 2020

CART19-BE-01: A Multicenter Trial of ARI-0001 Cell Therapy in Patients with CD19 Relapsed/Refractory Malignancies.

Authors:
Valentín Ortíz-Maldonado Susana Rives Maria Castellà Anna Alonso-Saladrigues Daniel Benítez-Ribas Miguel Caballero-Baños Tycho Baumann Joan Cid Enric Garcia-Rey Cristina Llanos Montserrat Torrebadell Neus Villamor Eva Giné Marina Díaz-Beyá Laia Guardia Mercedes Montoro Albert Català Anna Faura E Azucena González Marta Español-Rego Nela Klein-González Laia Alsina Pedro Castro Iolanda Jordan Sara Fernández Federico Ramos Guillermo Suñé Unai Perpiñá Josep M Canals Miquel Lozano Esteve Trias Andrea Scalise Sara Varea Joaquín Sáez-Peñataro Ferran Torres Gonzalo Calvo Jordi Esteve Álvaro Urbano-Ispizua Manel Juan Julio Delgado

Mol Ther 2020 Sep 20. Epub 2020 Sep 20.

Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain; University of Barcelona, Barcelona, Spain. Electronic address:

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September 2020

A low lymphocyte-to-monocyte ratio is an independent predictor of poorer survival and higher risk of histological transformation in follicular lymphoma.

Authors:
Pablo Mozas Andrea Rivero Alfredo Rivas-Delgado Ferran Nadeu Guillem Clot Juan Gonzalo Correa Carlos Castillo Alex Bataller Tycho Baumann Eva Giné Julio Delgado Neus Villamor Elías Campo Patricia Pérez-Galán Laura Magnano Armando López-Guillermo

Leuk Lymphoma 2021 Jan 19;62(1):104-111. Epub 2020 Sep 19.

Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain.

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January 2021

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms.

Authors:
Ferran Nadeu Rut Mas-de-Les-Valls Alba Navarro Romina Royo Silvia Martín Neus Villamor Helena Suárez-Cisneros Rosó Mares Junyan Lu Anna Enjuanes Alfredo Rivas-Delgado Marta Aymerich Tycho Baumann Dolors Colomer Julio Delgado Ryan D Morin Thorsten Zenz Xose S Puente Peter J Campbell Sílvia Beà Francesco Maura Elías Campo

Nat Commun 2020 07 7;11(1):3390. Epub 2020 Jul 7.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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July 2020

The BALL prognostic score identifies relapsed/refractory CLL patients who benefit the most from single-agent ibrutinib therapy.

Authors:
Stefano Molica Tycho S Baumann Mirella Lentini Luciano Levato Julio Delgado Emili Montserrat

Leuk Res 2020 08 10;95:106401. Epub 2020 Jun 10.

Department of Hematology, Institute of Hematology and Oncology, Hospital Clínic, University of Barcelona, Barcelona, Spain.

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August 2020

Point-Of-Care CAR T-Cell Production (ARI-0001) Using a Closed Semi-automatic Bioreactor: Experience From an Academic Phase I Clinical Trial.

Authors:
Maria Castella Miguel Caballero-Baños Valentín Ortiz-Maldonado Europa Azucena González-Navarro Guillermo Suñé Asier Antoñana-Vidósola Anna Boronat Berta Marzal Lucía Millán Beatriz Martín-Antonio Joan Cid Miquel Lozano Enric García Jaime Tabera Esteve Trias Unai Perpiña Josep Ma Canals Tycho Baumann Daniel Benítez-Ribas Elías Campo Jordi Yagüe Álvaro Urbano-Ispizua Susana Rives Julio Delgado Manel Juan

Front Immunol 2020 20;11:482. Epub 2020 Mar 20.

Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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March 2020

High serum levels of IL-2R, IL-6, and TNF-α are associated with higher tumor burden and poorer outcome of follicular lymphoma patients in the rituximab era.

Authors:
Pablo Mozas Alfredo Rivas-Delgado Andrea Rivero Iván Dlouhy Ferran Nadeu Olga Balagué Blanca González-Farré Tycho Baumann Eva Giné Julio Delgado Neus Villamor Elías Campo Patricia Pérez-Galán Xavier Filella Laura Magnano Armando López-Guillermo

Leuk Res 2020 07 19;94:106371. Epub 2020 May 19.

Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain; Universitat de Barcelona, Barcelona, Spain. Electronic address:

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July 2020

CLL and COVID-19 at the Hospital Clinic of Barcelona: an interim report.

Authors:
Tycho Baumann Julio Delgado Emili Montserrat

Leukemia 2020 07 19;34(7):1954-1956. Epub 2020 May 19.

Department of Hematology, Hospital Clinic University of Barcelona, Barcelona, Spain.

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July 2020

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.

Authors:
Adalgisa Condoluci Lodovico Terzi di Bergamo Petra Langerbeins Manuela A Hoechstetter Carmen D Herling Lorenzo De Paoli Julio Delgado Kari G Rabe Massimo Gentile Michael Doubek Francesca R Mauro Giorgia Chiodin Mattias Mattsson Jasmin Bahlo Giovanna Cutrona Jana Kotaskova Clara Deambrogi Karin E Smedby Valeria Spina Alessio Bruscaggin Wei Wu Riccardo Moia Elena Bianchi Bernhard Gerber Emanuele Zucca Silke Gillessen Michele Ghielmini Franco Cavalli Georg Stussi Mark A Hess Tycho S Baumann Antonino Neri Manlio Ferrarini Richard Rosenquist Francesco Forconi Robin Foà Sarka Pospisilova Fortunato Morabito Stephan Stilgenbauer Hartmut Döhner Sameer A Parikh William G Wierda Emili Montserrat Gianluca Gaidano Michael Hallek Davide Rossi

Blood 2020 May;135(21):1859-1869

Institute of Oncology Research, Università della Svizzera Italiana, Bellinzona, Switzerland.

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May 2020

Patterns of change in treatment, response, and outcome in patients with follicular lymphoma over the last four decades: a single-center experience.

Authors:
Pablo Mozas Ferran Nadeu Alfredo Rivas-Delgado Andrea Rivero Marta Garrote Olga Balagué Blanca González-Farré Luis Veloza Tycho Baumann Eva Giné Julio Delgado Neus Villamor Elías Campo Laura Magnano Armando López-Guillermo

Blood Cancer J 2020 03 5;10(3):31. Epub 2020 Mar 5.

Department of Hematology, Hospital Clínic, Barcelona, Spain.

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March 2020

Ibrutinib as initial therapy in chronic lymphocytic leukemia: A systematic review and meta-analysis.

Authors:
Stefano Molica Diana Giannarelli Tycho Baumann Emili Montserrat

Eur J Haematol 2020 May 22;104(5):512-515. Epub 2020 Feb 22.

Department of Hematology, Hospital Clinic, University of Barcelona, Barcelona, Spain.

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May 2020

The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome.

Authors:
Christian Brieghel Caspar da Cunha-Bang Christina Westmose Yde Ane Yde Schmidt Savvas Kinalis Ferran Nadeu Michael Asger Andersen Line Offenbach Jacobsen Mette Klarskov Andersen Lone Bredo Pedersen Julio Delgado Tycho Baumann Mattias Mattsson Larry Mansouri Richard Rosenquist Elias Campo Finn Cilius Nielsen Carsten Utoft Niemann

Clin Cancer Res 2020 03 9;26(6):1507-1515. Epub 2020 Jan 9.

Department of Hematology, Rigshospitalet, Copenhagen, Denmark.

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March 2020

Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions.

Authors:
Maria Castella Anna Boronat Raquel Martín-Ibáñez Vanina Rodríguez Guillermo Suñé Miguel Caballero Berta Marzal Lorena Pérez-Amill Beatriz Martín-Antonio Julio Castaño Clara Bueno Olga Balagué Europa Azucena González-Navarro Carles Serra-Pages Pablo Engel Ramon Vilella Daniel Benitez-Ribas Valentín Ortiz-Maldonado Joan Cid Jaime Tabera Josep M Canals Miquel Lozano Tycho Baumann Anna Vilarrodona Esteve Trias Elías Campo Pablo Menendez Álvaro Urbano-Ispizua Jordi Yagüe Patricia Pérez-Galán Susana Rives Julio Delgado Manel Juan

Mol Ther Methods Clin Dev 2019 Mar 6;12:134-144. Epub 2018 Dec 6.

Department of Immunology, CDB, Hospital Clínic de Barcelona, Villarroel 170, 08036 Barcelona, Spain.

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March 2019

Response duration and survival shorten after each relapse in patients with follicular lymphoma treated in the rituximab era.

Authors:
Alfredo Rivas-Delgado Laura Magnano Miriam Moreno-Velázquez Olga García Ferran Nadeu Pablo Mozas Ivan Dlouhy Tycho Baumann Jordina Rovira Blanca González-Farre Antonio Martínez Olga Balague Julio Delgado Neus Villamor Eva Giné Elías Campo Juan M Sancho-Cia Armando López-Guillermo

Br J Haematol 2019 03 4;184(5):753-759. Epub 2018 Dec 4.

Department of Haematology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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March 2019

Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia.

Authors:
Neus Giménez Alejandra Martínez-Trillos Arnau Montraveta Mónica Lopez-Guerra Laia Rosich Ferran Nadeu Juan G Valero Marta Aymerich Laura Magnano Maria Rozman Estella Matutes Julio Delgado Tycho Baumann Eva Gine Marcos González Miguel Alcoceba M José Terol Blanca Navarro Enrique Colado Angel R Payer Xose S Puente Carlos López-Otín Armando Lopez-Guillermo Elias Campo Dolors Colomer Neus Villamor

Haematologica 2019 03 27;104(3):576-586. Epub 2018 Sep 27.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBERONC, Barcelona.

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March 2019

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia.

Authors:
Renée Beekman Vicente Chapaprieta Núria Russiñol Roser Vilarrasa-Blasi Núria Verdaguer-Dot Joost H A Martens Martí Duran-Ferrer Marta Kulis François Serra Biola M Javierre Steven W Wingett Guillem Clot Ana C Queirós Giancarlo Castellano Julie Blanc Marta Gut Angelika Merkel Simon Heath Anna Vlasova Sebastian Ullrich Emilio Palumbo Anna Enjuanes David Martín-García Sílvia Beà Magda Pinyol Marta Aymerich Romina Royo Montserrat Puiggros David Torrents Avik Datta Ernesto Lowy Myrto Kostadima Maša Roller Laura Clarke Paul Flicek Xabier Agirre Felipe Prosper Tycho Baumann Julio Delgado Armando López-Guillermo Peter Fraser Marie-Laure Yaspo Roderic Guigó Reiner Siebert Marc A Martí-Renom Xose S Puente Carlos López-Otín Ivo Gut Hendrik G Stunnenberg Elias Campo Jose I Martin-Subero

Nat Med 2018 06 21;24(6):868-880. Epub 2018 May 21.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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June 2018

Expression of the transcribed ultraconserved region 70 and the related long non-coding RNA AC092652.2-202 has prognostic value in Chronic Lymphocytic Leukaemia.

Authors:
Riccardo Bomben Alejandro Roisman Tiziana D'Agaro Giancarlo Castellano Tycho Baumann Julio Delgado Armando López-Guillermo Antonella Zucchetto Michele Dal-Bo Vanessa Bravin Irma Slavutsky Anna Vlasova Roderic Guigó Jose I Martin-Subero Vicente Chapaprieta Renee Beekman David Martin-García Sílvia Beà Itziar Salaverria Marta Aymerich Elias Campo Valter Gattei Luis Hernández

Br J Haematol 2019 03 24;184(6):1045-1050. Epub 2018 Apr 24.

Lymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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March 2019

Analysis of criteria for treatment initiation in patients with progressive chronic lymphocytic leukemia.

Authors:
Pablo Mozas Alfredo Rivas-Delgado Tycho Baumann Neus Villamor Valentín Ortiz-Maldonado Marta Aymerich Dolors Costa Alba Navarro Eva Giné Armando López-Guillermo Emili Montserrat Julio Delgado

Blood Cancer J 2018 01 16;8(1):10. Epub 2018 Jan 16.

Department of Hematology, Institute of Hematology and Oncology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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January 2018

The mutational landscape of small lymphocytic lymphoma compared to non-early stage chronic lymphocytic leukemia.

Authors:
Alejandra Martínez-Trillos Magda Pinyol Julio Delgado Marta Aymerich Maria Rozman Tycho Baumann Marcos González-Díaz Jesus M Hernández Miguel Alcoceba Anna Muntañola Maria José Terol Blanca Navarro Eva Giné Pedro Jares Sílvia Beà Alba Navarro Dolors Colomer Ferran Nadeu Enrique Colado Angel R Payer Tomás García-Cerecedo Xosé S Puente Carlos López-Otin Elias Campo Armando López-Guillermo Neus Villamor

Leuk Lymphoma 2018 10 8;59(10):2318-2326. Epub 2017 Nov 8.

c Unitat d'Hematopatologia, Hospital Clínic de Barcelona, IDIBAPS, CIBERONC , Barcelona , Spain.

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October 2018

Is there a role for minimal residual disease monitoring in the management of patients with hairy-cell leukaemia?

Authors:
Valentín Ortiz-Maldonado Neus Villamor Tycho Baumann Marta Aymerich Laura Magnano Pablo Mozas Alfredo Rivas-Delgado Alejandra Martínez-Trillos Eva Giné Elías Campo Armando López-Guillermo Julio Delgado

Br J Haematol 2018 10 18;183(1):127-129. Epub 2017 Aug 18.

Department of Haematology, Hospital Clínic, IDIBAPS, Barcelona, Spain.

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October 2018

High serum levels of soluble interleukin-2 receptor (sIL2-R), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF) are associated with adverse clinical features and predict poor outcome in diffuse large B-cell lymphoma.

Authors:
Ivan Dlouhy Xavier Filella Jordina Rovira Laura Magnano Alfredo Rivas-Delgado Tycho Baumann Alejandra Martínez-Trillos Olga Balagué Antonio Martínez Blanca González-Farre Kennosuke Karube Eva Gine Julio Delgado Elías Campo Armando López-Guillermo

Leuk Res 2017 08 17;59:20-25. Epub 2017 May 17.

Department of Hematology, Hospital Clinic, Villarroel St. 170, 08036 Barcelona, Spain.

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August 2017

Massive erythrophagocytosis by peripheral monocytes and neutrophils in parvovirus-B19 autoimmune hemolytic anemia.

Authors:
Laura Puigví Tycho Baumann Sara Fernández Pedro Castro Arturo Pereira Anna Merino

Ann Hematol 2017 May 21;96(5):881-882. Epub 2017 Feb 21.

Biomedical Diagnostic Center, Hospital Clínic of Barcelona, Villarroel, 170, 08036, Barcelona, Spain.

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May 2017

Chronic lymphocytic leukemia: A prognostic model comprising only two biomarkers (IGHV mutational status and FISH cytogenetics) separates patients with different outcome and simplifies the CLL-IPI.

Authors:
Julio Delgado Michael Doubek Tycho Baumann Jana Kotaskova Stefano Molica Pablo Mozas Alfredo Rivas-Delgado Fortunato Morabito Sarka Pospisilova Emili Montserrat

Am J Hematol 2017 Apr 13;92(4):375-380. Epub 2017 Feb 13.

Department of Hematology, Institute of Hematology and Oncology, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

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April 2017

T-cell subsets in lymph nodes identify a subgroup of follicular lymphoma patients with favorable outcome.

Authors:
Laura Magnano Antonio Martínez Joaquim Carreras Alejandra Martínez-Trillos Eva Giné Jordina Rovira Ivan Dlouhy Tycho Baumann Olga Balagué Elías Campo Armando López-Guillermo Neus Villamor

Leuk Lymphoma 2017 04 11;58(4):842-850. Epub 2016 Aug 11.

b Hematopathology Unit, Department of Pathology , Hospital Clínic, IDIBAPS , Barcelona , Spain.

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April 2017

Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia.

Authors:
Tatjana Pandzic Jimmy Larsson Liqun He Snehangshu Kundu Kenneth Ban Muhammad Akhtar-Ali Anders R Hellström Anna Schuh Ruth Clifford Stuart J Blakemore Jonathan C Strefford Tycho Baumann Armando Lopez-Guillermo Elias Campo Viktor Ljungström Larry Mansouri Richard Rosenquist Tobias Sjöblom Mats Hellström

Clin Cancer Res 2016 Dec 8;22(24):6217-6227. Epub 2016 Mar 8.

Department of Immunology, Genetics and Pathology, Science for Life laboratory, Uppsala University, Uppsala, Sweden.

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December 2016

Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia.

Authors:
Cristina López Anke K Bergmann Ulrike Paul Eva M Murga Penas Inga Nagel Matthew J Betts Patricia Johansson Matthias Ritgen Tycho Baumann Marta Aymerich Sandrine Jayne Robert B Russell Elias Campo Martin J S Dyer Jan Dürig Reiner Siebert

Br J Haematol 2016 Apr 25;173(2):265-73. Epub 2016 Feb 25.

Institute for Human Genetics, Christian-Albrechts-University Kiel & University Hospital Schleswig Holstein, Kiel, Germany.

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April 2016

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

Authors:
Ferran Nadeu Julio Delgado Cristina Royo Tycho Baumann Tatjana Stankovic Magda Pinyol Pedro Jares Alba Navarro David Martín-García Sílvia Beà Itziar Salaverria Ceri Oldreive Marta Aymerich Helena Suárez-Cisneros Maria Rozman Neus Villamor Dolors Colomer Armando López-Guillermo Marcos González Miguel Alcoceba Maria José Terol Enrique Colado Xose S Puente Carlos López-Otín Anna Enjuanes Elías Campo

Blood 2016 04 2;127(17):2122-30. Epub 2016 Feb 2.

Lymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Hematology Department, Hospital Clínic, Barcelona, Spain; Departament d'Anatomia Patològica, Universitat de Barcelona, Barcelona, Spain.

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April 2016

CD49d (ITGA4) expression is a predictor of time to first treatment in patients with chronic lymphocytic leukaemia and mutated IGHV status.

Authors:
Tycho Baumann Julio Delgado Rodrigo Santacruz Alejandra Martínez-Trillos María Rozman Marta Aymerich Cristina López Dolors Costa Anna Carrió Neus Villamor Emili Montserrat

Br J Haematol 2016 Jan 12;172(1):48-55. Epub 2015 Nov 12.

Department of Haematology, Institute of Haematology and Oncology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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January 2016

Detection of chromothripsis-like patterns with a custom array platform for chronic lymphocytic leukemia.

Authors:
Itziar Salaverria David Martín-Garcia Cristina López Guillem Clot Manel García-Aragonés Alba Navarro Julio Delgado Tycho Baumann Magda Pinyol Idoia Martin-Guerrero Ana Carrió Dolors Costa Ana C Queirós Sandrine Jayne Marta Aymerich Neus Villamor Dolors Colomer Marcos González Armando López-Guillermo Elías Campo Martin J S Dyer Reiner Siebert Lluís Armengol Sílvia Beà

Genes Chromosomes Cancer 2015 Nov 25;54(11):668-80. Epub 2015 Aug 25.

Hematopathology Unit, Hospital Clínic Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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November 2015

Non-coding recurrent mutations in chronic lymphocytic leukaemia.

Authors:
Xose S Puente Silvia Beà Rafael Valdés-Mas Neus Villamor Jesús Gutiérrez-Abril José I Martín-Subero Marta Munar Carlota Rubio-Pérez Pedro Jares Marta Aymerich Tycho Baumann Renée Beekman Laura Belver Anna Carrio Giancarlo Castellano Guillem Clot Enrique Colado Dolors Colomer Dolors Costa Julio Delgado Anna Enjuanes Xavier Estivill Adolfo A Ferrando Josep L Gelpí Blanca González Santiago González Marcos González Marta Gut Jesús M Hernández-Rivas Mónica López-Guerra David Martín-García Alba Navarro Pilar Nicolás Modesto Orozco Ángel R Payer Magda Pinyol David G Pisano Diana A Puente Ana C Queirós Víctor Quesada Carlos M Romeo-Casabona Cristina Royo Romina Royo María Rozman Nuria Russiñol Itziar Salaverría Kostas Stamatopoulos Hendrik G Stunnenberg David Tamborero María J Terol Alfonso Valencia Nuria López-Bigas David Torrents Ivo Gut Armando López-Guillermo Carlos López-Otín Elías Campo

Nature 2015 Oct 22;526(7574):519-24. Epub 2015 Jul 22.

Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, 08036 Barcelona, Spain.

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October 2015

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia.

Authors:
David Rodríguez Gabriel Bretones Víctor Quesada Neus Villamor Javier R Arango Armando López-Guillermo Andrew J Ramsay Tycho Baumann Pedro M Quirós Alba Navarro Cristina Royo José I Martín-Subero Elías Campo Carlos López-Otín

Blood 2015 Jul 1;126(2):195-202. Epub 2015 Jun 1.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain;

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July 2015

Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption.

Authors:
Julio Delgado Itziar Salaverria Tycho Baumann Alejandra Martínez-Trillos Eriong Lee Laura Jiménez Alba Navarro Cristina Royo Rodrigo Santacruz Cristina López Angel R Payer Enrique Colado Marcos González Lluís Armengol Dolors Colomer Magda Pinyol Neus Villamor Marta Aymerich Ana Carrió Dolors Costa Guillem Clot Eva Giné Armando López-Guillermo Elías Campo Sílvia Beà

Haematologica 2014 Nov 4;99(11):e231-4. Epub 2014 Jul 4.

Hematopathology Unit, Hospital Clínic, IDIBAPS, Barcelona.

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November 2014

Chronic lymphocytic leukemia in the elderly: clinico-biological features, outcomes, and proposal of a prognostic model.

Authors:
Tycho Baumann Julio Delgado Rodrigo Santacruz Alejandra Martínez-Trillos Cristina Royo Alba Navarro Magda Pinyol María Rozman Arturo Pereira Neus Villamor Marta Aymerich Cristina López Anna Carrió Emili Montserrat

Haematologica 2014 Oct 27;99(10):1599-604. Epub 2014 Jun 27.

Institute of Hematology and Oncology, Department of Hematology, University of Barcelona, Barcelona, Spain

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October 2014

New treatment options for chronic lymphocytic leukemia.

Authors:
Julio Delgado Tycho Baumann Rodrigo Santacruz Emili Montserrat

Expert Opin Pharmacother 2014 Apr 22;15(6):823-32. Epub 2014 Feb 22.

University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institute of Hematology and Oncology, Hospital Clínic, Department of Hematology , Villaroel 170, 08036 Barcelona , Spain +34 93 227 54 75 ; +34 93 227 98 11 ;

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April 2014

Rituximab-based chemoimmunotherapy prolongs survival of patients with chronic lymphocytic leukemia independently of the time of administration.

Authors:
Julio Delgado Gabriela Ghita Tycho Baumann Rodrigo Santacruz Ivan Dlouhy Marta Aymerich Maria Rozman Natalia Creus Arturo Pereira Emili Montserrat

Clin Lymphoma Myeloma Leuk 2014 Feb 12;14(1):73-9. Epub 2013 Oct 12.

Institute of Hematology and Oncology, Department of Hematology, Hospital Clinic, IDIBAPS, Barcelona, Spain. Electronic address:

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February 2014

Clonal evolution in chronic lymphocytic leukemia: analysis of correlations with IGHV mutational status, NOTCH1 mutations and clinical significance.

Authors:
Cristina López Julio Delgado Dolors Costa Neus Villamor Alba Navarro Maite Cazorla Cándida Gómez Amparo Arias Concha Muñoz Sandra Cabezas Tycho Baumann María Rozman Marta Aymerich Dolors Colomer Arturo Pereira Francesc Cobo Armando López-Guillermo Elías Campo Ana Carrió

Genes Chromosomes Cancer 2013 Oct 26;52(10):920-7. Epub 2013 Jul 26.

Hematopathology Unit, Department of Pathology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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October 2013

MicroRNA expression in chronic lymphocytic leukemia developing autoimmune hemolytic anemia.

Authors:
Gerardo Ferrer Alfons Navarro Kate Hodgson Marta Aymerich Arturo Pereira Tycho Baumann Mariano Monzo Carol Moreno Emili Montserrat

Leuk Lymphoma 2013 Sep 29;54(9):2016-22. Epub 2013 Jan 29.

Institute of Hematology and Oncology, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

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September 2013

Retreatment with purine analogs in patients with chronic lymphocytic leukemia.

Authors:
Ivan Dlouhy Gabriela Ghita Tycho Baumann Eva Gine Neus Villamor Maria Rozman Alejandra Martinez-Trillos Armando Lopez-Guillermo Julio Delgado

Leuk Res 2012 Dec 28;36(12):1521-5. Epub 2012 Aug 28.

Institute of Hematology and Oncology, Department of Hematology, Hospital Clinic, Barcelona, Spain.

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December 2012

Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations.

Authors:
Cristina López Julio Delgado Dolors Costa Laura Conde Gabriela Ghita Neus Villamor Alba Navarro Maite Cazorla Cándida Gómez Amparo Arias Concha Muñoz Tycho Baumann María Rozman Marta Aymerich Dolors Colomer Francesc Cobo Elías Campo Armando López-Guillermo Emili Montserrat Ana Carrió

Genes Chromosomes Cancer 2012 Sep 23;51(9):881-9. Epub 2012 May 23.

Hematopathology Unit, Pathology Department, Hospital Clínic, Institut d'Investigacions Biomédiques Agustí Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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September 2012

Chronic lymphocytic leukemia therapy: beyond chemoimmunotherapy.

Authors:
Julio Delgado Tycho Baumann Gabriela Ghita Emili Montserrat

Curr Pharm Des 2012 ;18(23):3356-62

Institute of Hematology and Oncology, Department of Hematology, Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Spain.

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December 2012

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia.

Authors:
Víctor Quesada Laura Conde Neus Villamor Gonzalo R Ordóñez Pedro Jares Laia Bassaganyas Andrew J Ramsay Sílvia Beà Magda Pinyol Alejandra Martínez-Trillos Mónica López-Guerra Dolors Colomer Alba Navarro Tycho Baumann Marta Aymerich María Rozman Julio Delgado Eva Giné Jesús M Hernández Marcos González-Díaz Diana A Puente Gloria Velasco José M P Freije José M C Tubío Romina Royo Josep L Gelpí Modesto Orozco David G Pisano Jorge Zamora Miguel Vázquez Alfonso Valencia Heinz Himmelbauer Mónica Bayés Simon Heath Marta Gut Ivo Gut Xavier Estivill Armando López-Guillermo Xose S Puente Elías Campo Carlos López-Otín

Nat Genet 2011 Dec 11;44(1):47-52. Epub 2011 Dec 11.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.

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December 2011

A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia.

Authors:
Cristina López Tycho Baumann Dolors Costa Mónica López-Guerra Alba Navarro Cándida Gómez Amparo Arias Concha Muñoz María Rozman Neus Villamor Dolors Colomer Emili Montserrat Elías Campo Ana Carrió

Br J Haematol 2012 Mar 9;156(5):612-8. Epub 2011 Dec 9.

Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain.

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March 2012

Efficacy of lenalidomide in a patient with myelodysplastic syndrome with isolated del(5q) and JAK2V617F mutation.

Authors:
Meritxell Nomdedeu Margherita Maffioli Xavier Calvo Alejandra Martínez-Trillos Tycho Baumann Marina Díaz-Beyá Josep-Lluís Aguilar María Rozman Dolors Costa Jordi Esteve Francisco Cervantes Dolors Colomer Benet Nomdedeu

Leuk Res 2011 Sep 20;35(9):1276-8. Epub 2011 Jul 20.

Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain.

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September 2011

Combined analysis of levels of serum B-cell activating factor and a proliferation-inducing ligand as predictor of disease progression in patients with chronic lymphocytic leukemia.

Authors:
Gerardo Ferrer Kate Hodgson Arturo Pereira Manel Juan Montse Elena Dolors Colomer Gael Roué Marta Aymerich Tycho Baumann Emili Montserrat Carol Moreno

Leuk Lymphoma 2011 Nov 27;52(11):2064-8. Epub 2011 Jun 27.

Institute of Hematology and Oncology, Department of Hematology, University of Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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November 2011

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.

Authors:
Xose S Puente Magda Pinyol Víctor Quesada Laura Conde Gonzalo R Ordóñez Neus Villamor Georgia Escaramis Pedro Jares Sílvia Beà Marcos González-Díaz Laia Bassaganyas Tycho Baumann Manel Juan Mónica López-Guerra Dolors Colomer José M C Tubío Cristina López Alba Navarro Cristian Tornador Marta Aymerich María Rozman Jesús M Hernández Diana A Puente José M P Freije Gloria Velasco Ana Gutiérrez-Fernández Dolors Costa Anna Carrió Sara Guijarro Anna Enjuanes Lluís Hernández Jordi Yagüe Pilar Nicolás Carlos M Romeo-Casabona Heinz Himmelbauer Ester Castillo Juliane C Dohm Silvia de Sanjosé Miguel A Piris Enrique de Alava Jesús San Miguel Romina Royo Josep L Gelpí David Torrents Modesto Orozco David G Pisano Alfonso Valencia Roderic Guigó Mónica Bayés Simon Heath Marta Gut Peter Klatt John Marshall Keiran Raine Lucy A Stebbings P Andrew Futreal Michael R Stratton Peter J Campbell Ivo Gut Armando López-Guillermo Xavier Estivill Emili Montserrat Carlos López-Otín Elías Campo

Nature 2011 Jun 5;475(7354):101-5. Epub 2011 Jun 5.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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June 2011

Autoimmune cytopenia in chronic lymphocytic leukemia: prevalence, clinical associations, and prognostic significance.

Authors:
Carol Moreno Kate Hodgson Gerardo Ferrer Montse Elena Xavier Filella Arturo Pereira Tycho Baumann Emili Montserrat

Blood 2010 Dec 24;116(23):4771-6. Epub 2010 Aug 24.

Institute of Hematology and Oncology, Hematology Department, Hospital Clínic University of Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.

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December 2010

Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.

Authors:
Christian Meisel Joerg C Schefold Rene Pschowski Tycho Baumann Katrin Hetzger Jan Gregor Steffen Weber-Carstens Dietrich Hasper Didier Keh Heidrun Zuckermann Petra Reinke Hans-Dieter Volk

Am J Respir Crit Care Med 2009 Oct 9;180(7):640-8. Epub 2009 Jul 9.

Department of Medical Immunology, Charité Campus Mitte, Berlin, Germany.

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October 2009