Publications by authors named "Tychele N Turner"

23Publications

Precise breakpoint detection in a patient with 9p- syndrome.

Cold Spring Harb Mol Case Stud 2020 06 12;6(3). Epub 2020 Jun 12.

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1101/mcs.a005348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304358PMC
June 2020

Sex-Based Analysis of De Novo Variants in Neurodevelopmental Disorders.

Am J Hum Genet 2019 12 27;105(6):1274-1285. Epub 2019 Nov 27.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904808PMC
December 2019

Large-Scale Population-Based Assessment of Psychiatric Comorbidities in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder.

Authors:
Tychele N Turner

Biol Psychiatry 2019 10;86(8):e25-e27

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.08.012DOI Listing
October 2019

Clinical Phenotypes of Carriers of Mutations in CHD8 or Its Conserved Target Genes.

Biol Psychiatry 2020 01 30;87(2):123-131. Epub 2019 Jul 30.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington; Center for Child Health, Behavior, and Disabilities, Seattle Children's Autism Center, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925323PMC
January 2020

Molecular Genetic Anatomy and Risk Profile of Hirschsprung's Disease.

N Engl J Med 2019 Apr;380(15):1421-1432

From the Center for Complex Disease Genomics, Johns Hopkins University School of Medicine, Baltimore (J.M.T., A.Y.L., T.N.T., M.X.S., S.C., A.K., K.-D.H.N., C.B., A.C.); the Department of Genome Sciences, University of Washington School of Medicine (T.N.T., N.K., A.K., B.P.C., E.E.E.), and the Howard Hughes Medical Institute, University of Washington (E.E.E.) - both in Seattle; and Broad Institute of Harvard and MIT, Cambridge, MA (K.-D.H.N., N.G., S.G.).

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http://dx.doi.org/10.1056/NEJMoa1706594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596298PMC
April 2019

The Role of De Novo Noncoding Regulatory Mutations in Neurodevelopmental Disorders.

Trends Neurosci 2019 02 15;42(2):115-127. Epub 2018 Dec 15.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382467PMC
February 2019

The autism spectrum phenotype in ADNP syndrome.

Autism Res 2018 09 14;11(9):1300-1310. Epub 2018 Aug 14.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1002/aur.1980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203613PMC
September 2018

Recurrent de novo mutations in neurodevelopmental disorders: properties and clinical implications.

Genome Med 2017 11 27;9(1):101. Epub 2017 Nov 27.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA.

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https://genomemedicine.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s13073-017-0498-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704398PMC
November 2017

Clinical phenotype of ASD-associated haploinsufficiency.

Mol Autism 2017 5;8:54. Epub 2017 Oct 5.

Department of Psychiatry and Behavioral Sciences, University of Washington, CHDD Box 357920, Seattle, WA 98195 USA.

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http://dx.doi.org/10.1186/s13229-017-0173-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629761PMC
February 2018

Genomic Patterns of De Novo Mutation in Simplex Autism.

Cell 2017 Oct 28;171(3):710-722.e12. Epub 2017 Sep 28.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.08.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679715PMC
October 2017

Comorbid symptoms of inattention, autism, and executive cognition in youth with putative genetic risk.

J Child Psychol Psychiatry 2018 03 18;59(3):268-276. Epub 2017 Sep 18.

Department of Psychiatry, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1111/jcpp.12815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812799PMC
March 2018

denovo-db: a compendium of human de novo variants.

Nucleic Acids Res 2017 01 5;45(D1):D804-D811. Epub 2016 Oct 5.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1093/nar/gkw865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210614PMC
January 2017

Revealing rate-limiting steps in complex disease biology: The crucial importance of studying rare, extreme-phenotype families.

Bioessays 2016 06 8;38(6):578-86. Epub 2016 Apr 8.

Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/bies.201500203DOI Listing
June 2016

Molecular subtyping and improved treatment of neurodevelopmental disease.

Genome Med 2016 Feb 25;8(1):22. Epub 2016 Feb 25.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1186/s13073-016-0278-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766622PMC
February 2016

Proteins linked to autosomal dominant and autosomal recessive disorders harbor characteristic rare missense mutation distribution patterns.

Hum Mol Genet 2015 Nov 5;24(21):5995-6002. Epub 2015 Aug 5.

Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21210, USA and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA,

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http://dx.doi.org/10.1093/hmg/ddv309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354780PMC
November 2015

Excess of rare, inherited truncating mutations in autism.

Nat Genet 2015 Jun 11;47(6):582-8. Epub 2015 May 11.

1] Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA. [2] Howard Hughes Medical Institute, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/ng.3303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449286PMC
June 2015

Loss of δ-catenin function in severe autism.

Nature 2015 Apr 25;520(7545):51-6. Epub 2015 Mar 25.

1] Center for Complex Disease Genomics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] National Institute of Mental Health (NIMH) Autism Centers of Excellence (ACE) Genetics Consortium at the University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature14186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383723PMC
April 2015