Dr. Tursonjan Tokay, MD, PhD - Nazarbayev University - professor

Dr. Tursonjan Tokay

MD, PhD

Nazarbayev University

professor

Astana, Akmola | Kazakhstan

Main Specialties: Neuropathology

Additional Specialties: Neuroscience

Dr. Tursonjan Tokay, MD, PhD - Nazarbayev University - professor

Dr. Tursonjan Tokay

MD, PhD

Introduction

After graduation from Xinjiang Medical University, P.R. China in 1987, I was appointed for an academic position in the same University. I participated in Anatomy teaching and several research projects of the University. In 1999, I was honoured a Scholarship from “Chinese National Scholarship Council” and sent to France to complete his PhD program.
In 2005, after obtaining his PhD degree in Neurobiology with outstanding remarks (summa cum Laude), I was invited by University of Rostock / Germany to participate a national research project granted by Federal Ministry for Education and Research of Germany. In 2009, I was appointed for a permanent academic position at the University of Rostock.
Since July 2014, I’ve been working at Nazarbayev University. I teach Human Anatomy, Physiology, and Neuroscience for undergraduate/graduate students.
In brief, I have 31 years of academic, research, and administration experiences in the fields of biomedical sciences at 4 Universities in 4 different countries.

Primary Affiliation: Nazarbayev University - Astana, Akmola , Kazakhstan

Specialties:

Additional Specialties:

Research Interests:


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Publications

24Publications

571Reads

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82PubMed Central Citations

Mitochondrial complex IV mutation increases reactive oxygen species production and reduces lifespan in aged mice.

Acta Physiol (Oxf) 2019 04 20;225(4):e13214. Epub 2018 Nov 20.

Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany.

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http://doi.wiley.com/10.1111/apha.13214
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http://dx.doi.org/10.1111/apha.13214DOI Listing
April 2019
27 Reads
4.382 Impact Factor

nMET, A New Target in Recurrent Cancer.

Curr Cancer Drug Targets 2016 ;16(7):572-8

Department of Biology, Nazarbayev University, School of Science and Technology, 53 Kabanbay Batyr Ave., Astana, 010000, Republic of Kazakhstan.

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http://dx.doi.org/10.2174/1568009616666160105105250DOI Listing
October 2017
41 Reads
3.522 Impact Factor

Status Epilepticus Enhances Depotentiation after Fully Established LTP in an NMDAR-Dependent but GluN2B-Independent Manner.

Neural Plast 2016 3;2016:6592038. Epub 2016 Jan 3.

Oscar Langendorff Institute of Physiology, University of Rostock, Gertrudenstraße 9, 18057 Rostock, Germany.

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http://dx.doi.org/10.1155/2016/6592038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735914PMC
November 2016
18 Reads

Power of PTEN/AKT: Molecular switch between tumor suppressors and oncogenes.

Oncol Lett 2016 Jul 26;12(1):375-378. Epub 2016 May 26.

Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Republic of Kazakhstan.

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http://dx.doi.org/10.3892/ol.2016.4636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906924PMC
July 2016
10 Reads
0.987 Impact Factor

Long-range and short-range tumor-stroma networks synergistically contribute to tumor-associated epilepsy.

Oncotarget 2016 May;7(22):33451-60

Institute of Nano Biomedicine and Engineering, Department of Instrument Science and Engineering, Key Laboratory for Thin Film and Microfabrication Technology of Ministry of Education, School of Electronic Information and Electronic Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China.

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http://dx.doi.org/10.18632/oncotarget.7962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078109PMC
May 2016
13 Reads
6.359 Impact Factor

Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants.

PLoS One 2015 8;10(4):e0123863. Epub 2015 Apr 8.

Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Rostock, Germany; Interdisciplinary Faculty, University of Rostock, Rostock, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123863PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390344PMC
March 2016
32 Reads
3.234 Impact Factor

Pim-1 kinase as cancer drug target: An update.

Biomed Rep 2016 Feb 24;4(2):140-146. Epub 2015 Dec 24.

Department of Biology, Nazarbayev University School of Science and Technology, Astana 010000, Republic of Kazakhstan.

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http://dx.doi.org/10.3892/br.2015.561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734217PMC
February 2016
22 Reads

Stereotactic injection of cerebrospinal fluid from anti-NMDA receptor encephalitis into rat dentate gyrus impairs NMDA receptor function.

Brain Res 2016 Feb 23;1633:10-18. Epub 2015 Dec 23.

Oscar Langendorff Institute of Physiology, University of Rostock, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.12.027DOI Listing
February 2016
14 Reads
2.843 Impact Factor

NMDA receptor-dependent metaplasticity by high-frequency magnetic stimulation.

Neural Plast 2014 28;2014:684238. Epub 2014 Oct 28.

Oscar Langendorff Institute of Physiology, University of Rostock, Gertrudenstraße 9, 18057 Rostock, Germany.

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http://dx.doi.org/10.1155/2014/684238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227354PMC
May 2015
7 Reads
2 Citations

Effects of oxygen insufflation during pilocarpine-induced status epilepticus on mortality, tissue damage and seizures.

Epilepsy Res 2014 Jan 12;108(1):90-7. Epub 2013 Nov 12.

Oscar Langendorff Institute of Physiology, University of Rostock, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.eplepsyres.2013.10.017DOI Listing
January 2014
13 Reads
1 Citation
2.020 Impact Factor

Impaired D-serine-mediated cotransmission mediates cognitive dysfunction in epilepsy.

J Neurosci 2013 Aug;33(32):13066-80

Laboratory of Experimental Epileptology, Department of Epileptology and Institute of Molecular Psychiatry, University of Bonn, D-53127 Bonn, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.5423-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619718PMC
August 2013
33 Reads
9 Citations
6.344 Impact Factor

Enhanced NMDA receptor-dependent LTP in the epileptic CA1 area via upregulation of NR2B.

Neurobiol Dis 2013 Jun 8;54:183-93. Epub 2013 Jan 8.

Oscar Langendorff Institute of Physiology, University of Rostock, Gertrudenstrasse 9, 18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.nbd.2012.12.011DOI Listing
June 2013
28 Reads
14 Citations
5.080 Impact Factor

ZD7288 enhances long-term depression at early postnatal medial perforant path-granule cell synapses.

Neural Plast 2012 26;2012:237913. Epub 2012 Jun 26.

Oscar Langendorff Institute of Physiology, University of Rostock, 18057 Rostock, Germany.

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http://dx.doi.org/10.1155/2012/237913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390110PMC
November 2012
8 Reads
1 Citation

Upregulation of presynaptic mGluR2, but not mGluR3 in the epileptic medial perforant path.

Neuropharmacology 2012 Mar 17;62(4):1867-73. Epub 2011 Dec 17.

Oscar Langendorff Institute of Physiology, University of Rostock, Gertrudenstrasse 9, 18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.neuropharm.2011.12.012DOI Listing
March 2012
8 Reads
3 Citations
5.110 Impact Factor

The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation.

Biochem J 2010 Apr 28;428(1):113-24. Epub 2010 Apr 28.

EA4310, Inserm U982, DC2N, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Astrocyte and Vascular Niche, European Institute for Peptide Research (IFRMP 23), University of Rouen, Mont-Saint-Aignan, Normandy, France.

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http://dx.doi.org/10.1042/BJ20090867DOI Listing
April 2010
23 Reads
11 Citations
4.400 Impact Factor

HCN1 channels constrain DHPG-induced LTD at hippocampal Schaffer collateral-CA1 synapses.

Learn Mem 2009 Dec 25;16(12):769-76. Epub 2009 Nov 25.

Institute of Physiology, University of Rostock, 18055 Rostock, Germany.

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http://dx.doi.org/10.1101/lm.1556009DOI Listing
December 2009
15 Reads
4 Citations
3.660 Impact Factor

GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses.

Neurosci Lett 2009 Dec 1;467(1):20-5. Epub 2009 Oct 1.

Institute of Physiology, University of Rostock, Gertrudenstrasse 9, 18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.neulet.2009.09.053DOI Listing
December 2009
21 Reads
4 Citations
2.060 Impact Factor

Dopamine induces contraction in the proximal, but relaxation in the distal rat isolated small intestine.

Neurosci Lett 2009 Nov 3;465(1):21-6. Epub 2009 Sep 3.

Institute of Physiology, University of Rostock, Gertrudenstrasse 9, 18057 Rostock, Germany.

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http://dx.doi.org/10.1016/j.neulet.2009.08.080DOI Listing
November 2009
13 Reads
1 Citation
2.060 Impact Factor

High-frequency magnetic stimulation induces long-term potentiation in rat hippocampal slices.

Neurosci Lett 2009 Sep 17;461(2):150-4. Epub 2009 Jun 17.

Institute of Physiology, University of Rostock, Gertrudenstrasse 9, 18055 Rostock, Germany.

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http://dx.doi.org/10.1016/j.neulet.2009.06.032DOI Listing
September 2009
15 Reads
11 Citations
2.060 Impact Factor

High K+-induced contraction requires depolarization-induced Ca2+ release from internal stores in rat gut smooth muscle.

Acta Pharmacol Sin 2009 Aug 6;30(8):1123-31. Epub 2009 Jul 6.

Institute of Physiology, University of Rostock, Gertrudenstrasse 9, 18055 Rostock, Germany.

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http://dx.doi.org/10.1038/aps.2009.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006678PMC
August 2009
84 Reads
8 Citations
2.500 Impact Factor

Beta-amyloid peptide stimulates endozepine release in cultured rat astrocytes through activation of N-formyl peptide receptors.

Glia 2008 Oct;56(13):1380-9

INSERM U413, Laboratory of Cellular and Molecular Neuroendocrinology, University of Rouen, Mont-Saint-Aignan, France.

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http://dx.doi.org/10.1002/glia.20705DOI Listing
October 2008
79 Reads
4 Citations
6.031 Impact Factor

Beta-amyloid peptides stimulate endozepine biosynthesis in cultured rat astrocytes.

J Neurochem 2005 Aug;94(3):607-16

INSERM U413, European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology, UA CNRS, University of Rouen, Mont-Saint-Aignan, France.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03102.xDOI Listing
August 2005
27 Reads
2 Citations
4.281 Impact Factor

Somatostatin down-regulates the expression and release of endozepines from cultured rat astrocytes via distinct receptor subtypes.

J Neurochem 2005 Aug;94(3):561-71

European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology, INSERM U413, UA CNRS, University of Rouen, Mont-Saint-Aignan, France.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03076.xDOI Listing
August 2005
12 Reads
7 Citations
4.281 Impact Factor