Publications by authors named "Turgut Dogruluk"

8Publications

Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression.

Authors:
Yiu Huen Tsang Yumeng Wang Kathleen Kong Caitlin Grzeskowiak Oksana Zagorodna Turgut Dogruluk Hengyu Lu Nicole Villafane Venkata Hemanjani Bhavana Daniela Moreno Sarah H Elsea Han Liang Gordon B Mills Kenneth L Scott

Elife 2020 Apr 9;9. Epub 2020 Apr 9.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.

View Article and Find Full Text PDF
April 2020

Systematic Functional Annotation of Somatic Mutations in Cancer.

Authors:
Patrick Kwok-Shing Ng Jun Li Kang Jin Jeong Shan Shao Hu Chen Yiu Huen Tsang Sohini Sengupta Zixing Wang Venkata Hemanjani Bhavana Richard Tran Stephanie Soewito Darlan Conterno Minussi Daniela Moreno Kathleen Kong Turgut Dogruluk Hengyu Lu Jianjiong Gao Collin Tokheim Daniel Cui Zhou Amber M Johnson Jia Zeng Carman Ka Man Ip Zhenlin Ju Matthew Wester Shuangxing Yu Yongsheng Li Christopher P Vellano Nikolaus Schultz Rachel Karchin Li Ding Yiling Lu Lydia Wai Ting Cheung Ken Chen Kenna R Shaw Funda Meric-Bernstam Kenneth L Scott Song Yi Nidhi Sahni Han Liang Gordon B Mills

Cancer Cell 2018 03;33(3):450-462.e10

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

View Article and Find Full Text PDF
March 2018

Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer.

Authors:
Hengyu Lu Nicole Villafane Turgut Dogruluk Caitlin L Grzeskowiak Kathleen Kong Yiu Huen Tsang Oksana Zagorodna Angeliki Pantazi Lixing Yang Nicholas J Neill Young Won Kim Chad J Creighton Roel G Verhaak Gordon B Mills Peter J Park Raju Kucherlapati Kenneth L Scott

Cancer Res 2017 07 16;77(13):3502-3512. Epub 2017 May 16.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.

View Article and Find Full Text PDF
July 2017

Functional annotation of rare gene aberration drivers of pancreatic cancer.

Authors:
Yiu Huen Tsang Turgut Dogruluk Philip M Tedeschi Joanna Wardwell-Ozgo Hengyu Lu Maribel Espitia Nikitha Nair Rosalba Minelli Zechen Chong Fengju Chen Qing Edward Chang Jennifer B Dennison Armel Dogruluk Min Li Haoqiang Ying Joseph R Bertino Marie-Claude Gingras Michael Ittmann John Kerrigan Ken Chen Chad J Creighton Karina Eterovic Gordon B Mills Kenneth L Scott

Nat Commun 2016 Jan 25;7:10500. Epub 2016 Jan 25.

Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article and Find Full Text PDF
January 2016

Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.

Authors:
Turgut Dogruluk Yiu Huen Tsang Maribel Espitia Fengju Chen Tenghui Chen Zechen Chong Vivek Appadurai Armel Dogruluk Agna Karina Eterovic Penelope E Bonnen Chad J Creighton Ken Chen Gordon B Mills Kenneth L Scott

Cancer Res 2015 Dec 1;75(24):5341-54. Epub 2015 Dec 1.

Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas. Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas.

View Article and Find Full Text PDF
December 2015

Moesin is a glioma progression marker that induces proliferation and Wnt/β-catenin pathway activation via interaction with CD44.

Authors:
Xiaoping Zhu Fabiana C Morales Nitin Kumar Agarwal Turgut Dogruluk Mihai Gagea Maria-Magdalena Georgescu

Cancer Res 2013 Feb 5;73(3):1142-55. Epub 2012 Dec 5.

Department of Neuro-Oncology and Veterinary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 75390, USA.

View Article and Find Full Text PDF
February 2013

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.

Authors:
Han Liang Lydia W T Cheung Jie Li Zhenlin Ju Shuangxing Yu Katherine Stemke-Hale Turgut Dogruluk Yiling Lu Xiuping Liu Chao Gu Wei Guo Steven E Scherer Hannah Carter Shannon N Westin Mary D Dyer Roeland G W Verhaak Fan Zhang Rachel Karchin Chang-Gong Liu Karen H Lu Russell R Broaddus Kenneth L Scott Bryan T Hennessy Gordon B Mills

Genome Res 2012 Nov 1;22(11):2120-9. Epub 2012 Oct 1.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

View Article and Find Full Text PDF
November 2012

Characterization of cancer stem-like cells in chordoma.

Authors:
Esra Aydemir Omer Faruk Bayrak Fikrettin Sahin Basar Atalay Gamze Torun Kose Mustafa Ozen Serhat Sevli Altay Burak Dalan Mehmet Emir Yalvac Turgut Dogruluk Uğur Türe

J Neurosurg 2012 Apr 27;116(4):810-20. Epub 2012 Jan 27.

Department of Genetics and Bioengineering, Yeditepe University, Istanbul, Turkey.

View Article and Find Full Text PDF
April 2012