Publications by authors named "Tullia Lindsten"

40Publications

GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2.

Genes Dev 2015 Nov 5;29(22):2331-6. Epub 2015 Nov 5.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA;

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http://dx.doi.org/10.1101/gad.269324.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691887PMC
November 2015

Serine catabolism regulates mitochondrial redox control during hypoxia.

Cancer Discov 2014 Dec 3;4(12):1406-17. Epub 2014 Sep 3.

Cancer Biology and Genetics Program and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258153PMC
December 2014

Analysis of a lung defect in autophagy-deficient mouse strains.

Autophagy 2014 Jan 11;10(1):45-56. Epub 2013 Nov 11.

Immunology Program; Memorial Sloan-Kettering Cancer Center; New York, NY USA.

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http://dx.doi.org/10.4161/auto.26505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028323PMC
January 2014

Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia.

Cancer Biol Ther 2012 Sep 16;13(11):1102-11. Epub 2012 Aug 16.

Department of Radiation Oncology, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.

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http://www.tandfonline.com/doi/abs/10.4161/cbt.21144
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http://dx.doi.org/10.4161/cbt.21144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461816PMC
September 2012

Therapeutic targets in cancer cell metabolism and autophagy.

Nat Biotechnol 2012 Jul 10;30(7):671-8. Epub 2012 Jul 10.

Cancer Biology and Genetics Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nbt.2285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876738PMC
July 2012

Autophagy and ammonia.

Autophagy 2012 Jan 1;8(1):122-3. Epub 2012 Jan 1.

Cancer Biology and Genetics and Immunology Programs, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.4161/auto.8.1.18078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335992PMC
January 2012

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases.

Proc Natl Acad Sci U S A 2011 Jul 20;108(27):11121-6. Epub 2011 Jun 20.

Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.1107969108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131371PMC
July 2011

Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.

J Immunol 2010 Dec 12;185(12):7151-5. Epub 2010 Nov 12.

Abramson Family Cancer Research Institute, Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1003193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997140PMC
December 2010

Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK.

Eur J Neurosci 2009 Dec 25;30(11):2030-41. Epub 2009 Nov 25.

Department of Neurology, University of California, School of Medicine, Sacramento, CA, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2009.06988.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830116PMC
December 2009

Differing in vitro survival dependency of mouse and rat NG2+ oligodendroglial progenitor cells.

J Neurosci Res 2010 Apr;88(5):957-70

Department of Neurology, University of California, Davis, School of Medicine, Sacramento, California, USA.

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http://dx.doi.org/10.1002/jnr.22262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872551PMC
April 2010

Alpha4 is an essential regulator of PP2A phosphatase activity.

Mol Cell 2009 Oct;36(1):51-60

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650900685
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http://dx.doi.org/10.1016/j.molcel.2009.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761955PMC
October 2009

The role of cell death in sexually dimorphic muscle development: male-specific muscles are retained in female bax/bak knockout mice.

Dev Neurobiol 2008 Sep;68(11):1303-14

Department of Psychology, Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA.

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http://dx.doi.org/10.1002/dneu.20658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605847PMC
September 2008

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation.

Blood 2008 Aug 6;112(4):1493-502. Epub 2008 Jun 6.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.1182/blood-2008-02-137398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515143PMC
August 2008

The PP2A-associated protein alpha4 plays a critical role in the regulation of cell spreading and migration.

J Biol Chem 2007 Oct 10;282(40):29712-20. Epub 2007 Aug 10.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1074/jbc.M703159200DOI Listing
October 2007

Tumor necrosis factor receptor (TNFR)-associated factor 5 is a critical intermediate of costimulatory signaling pathways triggered by glucocorticoid-induced TNFR in T cells.

J Biol Chem 2006 Mar 1;281(13):8559-64. Epub 2006 Feb 1.

Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M512915200DOI Listing
March 2006

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.

Nat Immunol 2005 Dec 6;6(12):1236-44. Epub 2005 Nov 6.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ni1268DOI Listing
December 2005

Persistent fetal ocular vasculature in mice deficient in bax and bak.

Arch Ophthalmol 2005 Jun;123(6):797-802

Departments of Medicine, Pathology, and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.1001/archopht.123.6.797DOI Listing
June 2005

Growth factor regulation of autophagy and cell survival in the absence of apoptosis.

Cell 2005 Jan;120(2):237-48

Abramson Family Cancer Research Institute, Department of Cancer Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://biologia.i-learn.unito.it/pluginfile.php/3228/mod_res
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http://linkinghub.elsevier.com/retrieve/pii/S009286740401150
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http://dx.doi.org/10.1016/j.cell.2004.11.046DOI Listing
January 2005

Defining the role of the Bcl-2 family of proteins in the nervous system.

Neuroscientist 2005 Feb;11(1):10-5

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://journals.sagepub.com/doi/10.1177/1073858404269267
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http://dx.doi.org/10.1177/1073858404269267DOI Listing
February 2005

Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation.

Cancer Res 2004 Nov;64(22):8341-8

Department of Cancer Biology and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2284DOI Listing
November 2004

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis.

Science 2004 Oct;306(5696):695-8

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1100537DOI Listing
October 2004

The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool.

J Neurosci 2003 Dec;23(35):11112-9

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741039PMC
December 2003

Proapoptotic bcl-2 family members, Bax and Bak, are essential for developmental photoreceptor apoptosis.

Invest Ophthalmol Vis Sci 2003 Aug;44(8):3598-605

F. M. Kirby Center for Molecular Ophthalmology, Scheie Eye Institute, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1167/iovs.02-1113DOI Listing
August 2003

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.

J Cell Biol 2003 Jul;162(1):59-69

Department of Cancer Biology, Abramson Cancer Center, 421 Curie Blvd., BRB II/III, 445, Philadelphia, PA 19104-6160, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200302084
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http://dx.doi.org/10.1083/jcb.200302084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172724PMC
July 2003

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

Nat Immunol 2002 Oct 3;3(10):932-9. Epub 2002 Sep 3.

Abramson Family Cancer Research Institute, Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.nature.com/articles/ni834
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http://dx.doi.org/10.1038/ni834DOI Listing
October 2002

BAX and BAK mediate p53-independent suppression of tumorigenesis.

Cancer Cell 2002 Sep;2(3):193-203

Center for Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Rutgers University, 679 Hoes Lane, Room 140, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/s1535-6108(02)00126-5DOI Listing
September 2002

Bax and Bak independently promote cytochrome C release from mitochondria.

J Biol Chem 2002 Apr 8;277(16):14127-34. Epub 2002 Feb 8.

Department of Molecular Biology, the Cancer Institute of New Jersey, Rutgers University, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1074/jbc.M109939200DOI Listing
April 2002