Tsuyoshi Hamaguchi

Tsuyoshi Hamaguchi

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Tsuyoshi Hamaguchi

Tsuyoshi Hamaguchi

Publications by authors named "Tsuyoshi Hamaguchi"

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Specific amyloid-β42 deposition in the brain of a Gerstmann-Sträussler-Scheinker disease patient with a P105L mutation on the prion protein gene.

Prion 2018 13;12(5-6):315-319. Epub 2018 Nov 13.

a Department of Neurology and Neurological Science , Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences , Yushima Bunkyo-ku , Tokyo , Japan.

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https://www.tandfonline.com/doi/full/10.1080/19336896.2018.1
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http://dx.doi.org/10.1080/19336896.2018.1541689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277180PMC
July 2019

Age at onset in genetic prion disease and the design of preventive clinical trials.

Neurology 2019 Jul 6;93(2):e125-e134. Epub 2019 Jun 6.

From Broad Institute of MIT and Harvard (E.V.M., S.M.V.), Cambridge; Analytical and Translational Genetics Unit (E.V.M.), Massachusetts General Hospital; Program in Biological and Biomedical Sciences (E.V.M., S.M.V.), Harvard Medical School, Boston; Prion Alliance (E.V.M., S.M.V.), Cambridge; Harvard Business School (M.C.O.), Boston, MA; Institut du Cerveau et de la Moelle Épinière (J.-P.B., S.H.), ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université; Cellule Nationale de Référence des Maladies de Creutzfeldt-Jakob (J.-P.B., S.H., J.-L.P.), Assistance Publique-Hôpitaux de Paris, France; National Reference Center for TSE (I.Z., C.P., P.H., T.K.), Georg-August University, Göttingen, Germany; IRCCS-Istituto delle Scienze Neurologiche di Bologna (P.P., S.C.); Departments of Experimental, Diagnostic and Specialty Medicine (P.P.) and Biomedical and Neuromotor Sciences (S.C.), University of Bologna, Italy; National Prion Disease Pathology Surveillance Center (J.S.), Case Western Reserve University, Cleveland, OH; MRC Prion Unit at UCL (J.K., S.M.), Institute of Prion Diseases, University College London, UK; Memory and Aging Center (J.C.F., L.T.T., M.D.G.), University of California San Francisco; Australian National CJD Registry (C.S., S.J.C.), University of Melbourne, Parkville, Australia; Department of Neurological Science (T.K.), Tohoku University Graduate School of Medicine, Sendai; Department of Public Health (R.A., Y.N.), Jichi Medical University, Shimotsuke; Department of Neurology and Neurobiology of Aging (T.H., M.Y.), Kanazawa University Graduate School of Medical Sciences, Kanazawa; Department of Neurology and Neurological Science (N.S.), Tokyo Medical and Dental University; National Center of Neurology and Psychiatry (T.T., H.M.), Kodaira, Japan; Laboratory of Prion Neurobiology (R.C.), Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan; AULSS2 Ca' Foncello Hospital (I.R.), Treviso, Italy; Spanish National Reference Center for CJD (J.d.P.-C., M.C.), Instituto de Salud Carlos III and CIBERNED, Madrid, Spain; and NHS National Prion Clinic (S.M.), National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007745DOI Listing
July 2019

Rosmarinic acid suppresses Alzheimer's disease development by reducing amyloid β aggregation by increasing monoamine secretion.

Sci Rep 2019 Jun 18;9(1):8711. Epub 2019 Jun 18.

Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.

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http://dx.doi.org/10.1038/s41598-019-45168-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581955PMC
June 2019

Neuronal intranuclear inclusion disease showing blepharoptosis and positive serum anti-acetylcholine receptor antibody without myasthenia gravis.

J Neurol Sci 2019 May 16;400:119-121. Epub 2019 Mar 16.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.03.013DOI Listing
May 2019

Cerebral hemorrhagic stroke associated with cerebral amyloid angiopathy in young adults about 3 decades after neurosurgeries in their infancy.

J Neurol Sci 2019 Apr 1;399:3-5. Epub 2019 Feb 1.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.01.051DOI Listing
April 2019

The sulfation code for propagation of neurodegeneration.

J Biol Chem 2018 07;293(27):10841-10842

From the Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa 920-8640, Japan.

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http://dx.doi.org/10.1074/jbc.H118.003970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036190PMC
July 2018

Cerebral Amyloid Angiopathy-Related Microbleeds and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease.

J Alzheimers Dis 2017 ;55(3):905-913

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.

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http://dx.doi.org/10.3233/JAD-160651DOI Listing
February 2018

Biochemical features of genetic Creutzfeldt-Jakob disease with valine-to-isoleucine substitution at codon 180 on the prion protein gene.

Biochem Biophys Res Commun 2018 02 31;496(4):1055-1061. Epub 2018 Jan 31.

Department of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, 1-5-45 Yushima Bunkyo-ku, Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2018.01.119DOI Listing
February 2018

Demyelinating polyneuropathy after long-term treatment with infliximab.

Int J Rheum Dis 2017 Nov 14;20(11):1781-1782. Epub 2015 Jul 14.

Department of Neurology and Neurobiology of Ageing, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1111/1756-185X.12642DOI Listing
November 2017

Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis.

J Neurol Sci 2017 10 31;381:144-146. Epub 2017 Aug 31.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jns.2017.08.3240DOI Listing
October 2017

Granuloma formation in a patient with GNE myopathy: A case report.

Neuromuscul Disord 2017 Feb 18;27(2):183-184. Epub 2016 Nov 18.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.nmd.2016.11.007DOI Listing
February 2017

Significant association of cadaveric dura mater grafting with subpial Aβ deposition and meningeal amyloid angiopathy.

Acta Neuropathol 2016 08 17;132(2):313-5. Epub 2016 Jun 17.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.

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http://dx.doi.org/10.1007/s00401-016-1588-3DOI Listing
August 2016

Cerebral Amyloid Angiopathy-Related Microbleeds Correlate with Glucose Metabolism and Brain Volume in Alzheimer's Disease.

J Alzheimers Dis 2015 ;48(2):517-28

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.3233/JAD-150274DOI Listing
June 2016

Quantifying prion disease penetrance using large population control cohorts.

Sci Transl Med 2016 Jan;8(322):322ra9

Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA. Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad5169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774245PMC
January 2016

Progression of Seed-Induced Aβ Deposition within the Limbic Connectome.

Brain Pathol 2015 Nov 24;25(6):743-52. Epub 2015 Mar 24.

Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1111/bpa.12252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530099PMC
November 2015

Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.

Adv Exp Med Biol 2015 ;863:79-94

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1, Takara-machi, Kanazawa, 920-8640, Japan,

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http://dx.doi.org/10.1007/978-3-319-18365-7_4DOI Listing
October 2015

Creutzfeldt-Jakob disease associated with a V203I homozygous mutation in the prion protein gene.

Prion 2014 ;8(5):336-8

a Department of Neurology and Neurobiology of Aging ; Kanazawa University Graduate School of Medical Sciences ; Kanazawa , Japan.

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http://dx.doi.org/10.4161/19336896.2014.971569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601383PMC
September 2015

Evaluation of dysphagia at the initial diagnosis of amyotrophic lateral sclerosis.

Auris Nasus Larynx 2015 Jun 18;42(3):213-7. Epub 2014 Nov 18.

Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.anl.2014.10.012DOI Listing
June 2015

[Clinical manifestations and epidemiology of prion diseases in Japan].

Rinsho Shinkeigaku 2013 ;23(11):1246-8

Department of Neurology, Kanazawa University Hospital.

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April 2015

Neurolymphomatosis exhibiting repeated exacerbation and remission in both the peripheral and central nervous systems.

J Neurol Sci 2014 Oct 24;345(1-2):267-8. Epub 2014 Jul 24.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa 920-8640, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2014.07.038DOI Listing
October 2014

Multiple factors contribute to the peripheral induction of cerebral β-amyloidosis.

J Neurosci 2014 Jul;34(31):10264-73

Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, D-72076 Tübingen, Germany, German Center for Neurodegenerative Diseases, D-72076 Tübingen, Germany, and

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http://dx.doi.org/10.1523/JNEUROSCI.1608-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608275PMC
July 2014

Exogenous amyloidogenic proteins function as seeds in amyloid β-protein aggregation.

Biochim Biophys Acta 2014 Apr 14;1842(4):646-53. Epub 2014 Jan 14.

Department of Neurology and Neurobiology and Aging, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.01.002DOI Listing
April 2014

Myasthenia gravis: predictive factors associated with the synchronized elevation of anti-acetylcholine receptor antibody titer in Kanazawa, Japan.

J Neuroimmunol 2014 Feb 22;267(1-2):97-101. Epub 2013 Dec 22.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jneuroim.2013.12.011DOI Listing
February 2014

Insight into the frequent occurrence of dura mater graft-associated Creutzfeldt-Jakob disease in Japan.

J Neurol Neurosurg Psychiatry 2013 Oct 17;84(10):1171-5. Epub 2013 Apr 17.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1136/jnnp-2012-304850DOI Listing
October 2013

Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats.

J Neurochem 2012 Mar 18;120(5):660-6. Epub 2011 Nov 18.

Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07551.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293176PMC
March 2012

The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain.

Acta Neuropathol 2012 Jan 20;123(1):31-7. Epub 2011 Nov 20.

Department of Cellular Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00401-011-0912-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297471PMC
January 2012

Serum tau protein as a marker for the diagnosis of Creutzfeldt-Jakob disease.

J Neurol 2011 Aug 1;258(8):1464-8. Epub 2011 Mar 1.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8640, Japan.

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http://dx.doi.org/10.1007/s00415-011-5960-xDOI Listing
August 2011

Familial ALS with G298S mutation in TARDBP: a comparison of CSF tau protein levels with those in sporadic ALS.

Intern Med 2010 15;49(12):1209-12. Epub 2010 Jun 15.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.2169/internalmedicine.49.3300DOI Listing
March 2011

REVIEW: Curcumin and Alzheimer's disease.

CNS Neurosci Ther 2010 Oct;16(5):285-97

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Japan.

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http://dx.doi.org/10.1111/j.1755-5949.2010.00147.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493893PMC
October 2010

Multiple cranial nerve enhancement on MRI in primary Sjögren's syndrome.

Intern Med 2010 30;49(9):857-9. Epub 2010 Apr 30.

Department of Neurology, Noto General Hospital, Nanao.

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http://dx.doi.org/10.2169/internalmedicine.49.3236DOI Listing
August 2010

Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway.

Am J Pathol 2009 Dec 5;175(6):2557-65. Epub 2009 Nov 5.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Takara-machi, Kanazawa, Japan.

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http://dx.doi.org/10.2353/ajpath.2009.090417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789642PMC
December 2009

[Prion disease surveillance in Japan: analysis of 1,241 patients].

Rinsho Shinkeigaku 2009 Nov;49(11):939-42

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science.

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November 2009

Dura mater graft-associated Creutzfeldt-Jakob disease in Japan: clinicopathological and molecular characterization of the two distinct subtypes.

Neuropathology 2009 Oct 29;29(5):609-18. Epub 2009 Jul 29.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2008.00987.xDOI Listing
October 2009

The risk of iatrogenic Creutzfeldt-Jakob disease through medical and surgical procedures.

Neuropathology 2009 Oct 29;29(5):625-31. Epub 2009 Jul 29.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2009.01023.xDOI Listing
October 2009

Hereditary rimmed vacuole myopathy showing interstitial amyloid deposition in muscle tissue.

Muscle Nerve 2009 Sep;40(3):472-5

Department of Neurology, Ishikawa Prefectural Central Hospital, 2-1 Kuratsukihigashi, Kanazawa 920-8530, Japan.

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http://dx.doi.org/10.1002/mus.21373DOI Listing
September 2009

Basiparallel anatomic scanning-magnetic resonance imaging in vertebral artery dissection.

Arch Neurol 2009 Feb;66(2):276-7

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa 920-8640, Japan.

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http://dx.doi.org/10.1001/archneurol.2008.528DOI Listing
February 2009

[Genetic factors for cerebral amyloid angiopathy].

Brain Nerve 2008 Nov;60(11):1275-83

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13 1 Takara-machi, Kanazawa 920-8641, Japan.

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November 2008

Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult.

Emerg Infect Dis 2008 May;14(5):828-30

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa 920-8640, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600258PMC
http://dx.doi.org/10.3201/eid1405.071121DOI Listing
May 2008

[Epidemiology and surveillance system of prion disease in Japan].

Nihon Rinsho 2007 Aug;65(8):1379-83

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science.

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August 2007

Carotid duplex ultrasonography during head-up tilt in patients with orthostatic hypotension.

Eur Neurol 2007 20;57(4):219-22. Epub 2007 Feb 20.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1159/000100014DOI Listing
June 2007

Ophthalmic surgery in prion diseases.

Emerg Infect Dis 2007 Jan;13(1):162-4

Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725820PMC
http://dx.doi.org/10.3201/eid1301.061004DOI Listing
January 2007

Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease.

Biochim Biophys Acta 2006 Jun 7;1762(6):575-86. Epub 2006 Apr 7.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, Japan.

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http://dx.doi.org/10.1016/j.bbadis.2006.03.002DOI Listing
June 2006