Tsutomu Tomita

Tsutomu Tomita

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Tsutomu Tomita

Tsutomu Tomita

Publications by authors named "Tsutomu Tomita"

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37Publications

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Effect of tofogliflozin on cardiac and vascular endothelial function in patients with type 2 diabetes and heart diseases: A pilot study.

J Diabetes Investig 2019 Jul 30. Epub 2019 Jul 30.

Division of Endocrinology and Metabolism, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

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http://dx.doi.org/10.1111/jdi.13122DOI Listing
July 2019

Novel angiogenesis therapeutics by redox injectable hydrogel - Regulation of local nitric oxide generation for effective cardiovascular therapy.

Biomaterials 2018 06 13;167:143-152. Epub 2018 Mar 13.

Department of Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8573, Japan; Master's School of Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan; Center for Research in Isotopes and Environmental Dynamics (CRiED), University of Tsukuba, Tennoudai 1-1-1, Tsukuba, Ibaraki 305-8573, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.03.023DOI Listing
June 2018

Effect of Keishibukuryogan, a Japanese Traditional Kampo Prescription, on Improvement of Microcirculation and Oketsu and Induction of Endothelial Nitric Oxide: A Live Imaging Study.

Evid Based Complement Alternat Med 2017 13;2017:3620130. Epub 2017 Jul 13.

Center for Integrative Medicine, Tsukuba University of Technology, 4-12-7 Kasuga, Tsukuba, Ibaraki 3058521, Japan.

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http://dx.doi.org/10.1155/2017/3620130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530408PMC
July 2017

Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells.

Calcif Tissue Int 2017 03 10;100(3):286-297. Epub 2016 Nov 10.

Internal Medicine 1, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.

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http://dx.doi.org/10.1007/s00223-016-0211-xDOI Listing
March 2017

Kangen-karyu raises surface body temperature through oxidative stress modification.

J Clin Biochem Nutr 2016 May 2;58(3):167-73. Epub 2016 Apr 2.

Center for Integrative Medicine, Tsukuba University of Technology, 4-12-7 Kasuga, Tsukuba 305-8521, Japan.

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http://dx.doi.org/10.3164/jcbn.15-135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865592PMC
May 2016

The G-Protein-Coupled Long-Chain Fatty Acid Receptor GPR40 and Glucose Metabolism.

Front Endocrinol (Lausanne) 2014 26;5:152. Epub 2014 Sep 26.

Medical Innovation Center, Kyoto University Graduate School of Medicine , Kyoto , Japan.

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http://dx.doi.org/10.3389/fendo.2014.00152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176464PMC
October 2014

Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion.

J Clin Biochem Nutr 2014 Jan 9;54(1):12-7. Epub 2013 Nov 9.

Faculty of Medicine, University of Tsukuba, 1-1-1 Ten-noudai, Tsukuba, Ibaraki 305-8573, Japan.

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http://dx.doi.org/10.3164/jcbn.13-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882482PMC
January 2014

Generation of leptin-deficient Lepmkyo/Lepmkyo rats and identification of leptin-responsive genes in the liver.

Physiol Genomics 2013 Sep 25;45(17):786-93. Epub 2013 Jun 25.

Department of Experimental Therapeutics, Translational Research Center, Kyoto University Hospital, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1152/physiolgenomics.00040.2013DOI Listing
September 2013

An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice.

Gastroenterology 2012 Oct 3;143(4):1027-36.e3. Epub 2012 Jul 3.

Department of Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1053/j.gastro.2012.06.043DOI Listing
October 2012

Glucocorticoid reamplification within cells intensifies NF-kappaB and MAPK signaling and reinforces inflammation in activated preadipocytes.

Am J Physiol Endocrinol Metab 2010 May 23;298(5):E930-40. Epub 2009 Sep 23.

Division of Endocrinology and Metabolism, Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54, Shogoin Kawaharacho, Sakyoku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1152/ajpendo.00320.2009DOI Listing
May 2010

Relevant use of Klotho in FGF19 subfamily signaling system in vivo.

Proc Natl Acad Sci U S A 2010 Jan 8;107(4):1666-71. Epub 2010 Jan 8.

Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Sakyo-Ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1073/pnas.0913986107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824417PMC
January 2010

Image analyses of conjunctival hyperemia in guinea pig allergic conjunctivitis.

Graefes Arch Clin Exp Ophthalmol 2009 Nov 21;247(11):1571-2. Epub 2009 Jun 21.

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http://dx.doi.org/10.1007/s00417-009-1123-5DOI Listing
November 2009

Image analyses of the kinetic changes of conjunctival hyperemia in histamine-induced conjunctivitis in Guinea pigs.

Cornea 2009 Jul;28(6):694-8

Department of Ophthalmology and Visual Science, Kochi Medical School, Nankoku, Japan; and daggerCine-Science Laboratory Co, Ltd, Tokyo, Japan. fukusima@ kochi-u.ac.jp

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ICO.0b013e3181a18acdDOI Listing
July 2009

Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis.

J Biol Chem 2007 Oct 6;282(40):29574-83. Epub 2007 Aug 6.

Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1074/jbc.M705972200DOI Listing
October 2007

Augmentation of 11beta-hydroxysteroid dehydrogenase type 1 in LPS-activated J774.1 macrophages--role of 11beta-HSD1 in pro-inflammatory properties in macrophages.

FEBS Lett 2007 Feb 27;581(3):349-54. Epub 2006 Nov 27.

Division of Endocrinology and Metabolism, Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawaharacho, Sakyoku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.febslet.2006.11.032DOI Listing
February 2007

Danaparoid sodium reduces ischemia/reperfusion-induced liver injury in rats by attenuating inflammatory responses.

Thromb Haemost 2007 Jan;97(1):81-7

Department of Biodefense Medicine, Nagoya City University Graduate School of Medical Sciences, Japan.

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January 2007

Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas.

Cell Metab 2006 Jan;3(1):59-65

Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.cmet.2005.12.005DOI Listing
January 2006

GPR40 gene expression in human pancreas and insulinoma.

Biochem Biophys Res Commun 2005 Dec 2;338(4):1788-90. Epub 2005 Nov 2.

Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.10.161DOI Listing
December 2005

CCAAT/enhancer binding protein alpha maintains the ability of insulin-stimulated GLUT4 translocation in 3T3-C2 fibroblastic cells.

Biochim Biophys Acta 2005 Aug 19;1745(1):38-47. Epub 2005 Jan 19.

Division of Endocrinology and Metabolism, Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1016/j.bbamcr.2004.12.007DOI Listing
August 2005

Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure.

Congest Heart Fail 2005 Jan-Feb;11(1):12-6

Third Department of Internal Medicine, Faculty of Medicine, Fukui, Shimoaituski 23, Yoshida-gun, Matsuoka-cho, Fukui 910-1193 Japan.

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May 2005

An angiotensin II AT1 receptor antagonist, telmisartan augments glucose uptake and GLUT4 protein expression in 3T3-L1 adipocytes.

FEBS Lett 2004 Oct;576(3):492-7

Division of Endocrinology and Metabolism, Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54, Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.febslet.2004.09.027DOI Listing
October 2004

[Transgenic mouse model of type 1 diabetes mellitus].

Nihon Rinsho 2002 Aug;60 Suppl 8:70-4

Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine.

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August 2002

[Transgenic mouse model of type 2 diabetes mellitus with insulin secretion insufficient].

Nihon Rinsho 2002 Aug;60 Suppl 8:75-8

Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine.

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August 2002