Tsui-Chun Tsou

Tsui-Chun Tsou

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Tsui-Chun Tsou

Publications by authors named "Tsui-Chun Tsou"

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Fibroblast growth factor 21 secretion enhances glucose uptake in mono(2-ethylhexyl)phthalate-treated adipocytes.

Toxicol In Vitro 2019 Sep 19;59:246-254. Epub 2019 Apr 19.

National Institute of Environmental Health Sciences, National Health Research Institutes, Zhunan, Miaoli 350, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2019.04.021DOI Listing
September 2019

National surveillance of 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins/furans in soil in Taiwan.

Chemosphere 2018 Jul 29;203:239-252. Epub 2018 Mar 29.

Department of Environmental Engineering, National Cheng Kung University, Tainan City 710, Taiwan.

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http://dx.doi.org/10.1016/j.chemosphere.2018.03.191DOI Listing
July 2018

Comparative microarray analyses of mono(2-ethylhexyl)phthalate impacts on fat cell bioenergetics and adipokine network.

Cell Biol Toxicol 2017 12 12;33(6):511-526. Epub 2017 Jan 12.

National Institute of Environmental Health Sciences, National Health Research Institutes, 35 Keyan Road, Zhunan, Miaoli, 350, Taiwan.

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http://dx.doi.org/10.1007/s10565-016-9380-7DOI Listing
December 2017

Estrogenic chemicals at body burden levels attenuate energy metabolism in 3T3-L1 adipocytes.

J Appl Toxicol 2017 Dec 28;37(12):1537-1546. Epub 2017 Aug 28.

National Institute of Environmental Health Sciences, National Health Research Institutes, Zhunan, Miaoli, 350, Taiwan.

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http://dx.doi.org/10.1002/jat.3508DOI Listing
December 2017

Development of an in Vitro-Based Risk Assessment Framework for Predicting Ambient Particulate Matter-Bound Polycyclic Aromatic Hydrocarbon-Activated Toxicity Pathways.

Environ Sci Technol 2017 Dec 1;51(24):14262-14272. Epub 2017 Dec 1.

National Institute of Environmental Health Sciences, National Health Research Institutes , Zhunan, Taiwan 35053, ROC.

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http://dx.doi.org/10.1021/acs.est.7b02002DOI Listing
December 2017

Estrogenic effects in the influents and effluents of the drinking water treatment plants.

Environ Sci Pollut Res Int 2016 May 20;23(9):8518-28. Epub 2016 Jan 20.

Emerging Compounds Research Center, Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Neipu, Pingtung County, 912, Taiwan.

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http://dx.doi.org/10.1007/s11356-015-5946-9DOI Listing
May 2016

Mono(2-ethylhexyl)phthalate accumulation disturbs energy metabolism of fat cells.

Arch Toxicol 2016 Mar 28;90(3):589-601. Epub 2014 Dec 28.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan, Miaoli, 350, Taiwan.

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http://dx.doi.org/10.1007/s00204-014-1446-9DOI Listing
March 2016

O(6) -methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma.

Int J Cancer 2015 Sep 6;137(6):1291-305. Epub 2015 Mar 6.

Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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http://dx.doi.org/10.1002/ijc.29486DOI Listing
September 2015

Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo.

Biochem Pharmacol 2015 May 20;95(1):28-37. Epub 2015 Mar 20.

Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC; National Institute of Cancer Research, National Health Research Institutes, Tainan 704, Taiwan, ROC; Division of Hematology/Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.03.006DOI Listing
May 2015

Six-month follow-up study of health markers of nanomaterials among workers handling engineered nanomaterials.

Nanotoxicology 2014 Aug 3;8 Suppl 1:100-10. Epub 2013 Dec 3.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes , Miaoli , Taiwan .

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http://dx.doi.org/10.3109/17435390.2013.858793DOI Listing
August 2014

A recombinant PPRE-driven luciferase bioassay for identification of potential PPAR agonists.

Vitam Horm 2014 ;94:427-35

Laboratory of Molecular Toxicology, Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-800095-3.00015-8DOI Listing
August 2014

Combination of a fast cleanup procedure and a DR-CALUX® bioassay for dioxin surveillance in Taiwanese soils.

Int J Environ Res Public Health 2014 May 6;11(5):4886-904. Epub 2014 May 6.

Emerging Compounds Research Center, Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Neipu, Pingtung County 912, Taiwan.

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http://dx.doi.org/10.3390/ijerph110504886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053921PMC
May 2014

Effect of nanoparticles exposure on fractional exhaled nitric oxide (FENO) in workers exposed to nanomaterials.

Int J Mol Sci 2014 Jan 9;15(1):878-94. Epub 2014 Jan 9.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Miaoli 350, Taiwan.

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http://dx.doi.org/10.3390/ijms15010878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907844PMC
January 2014

Crucial role of Toll-like receptors in the zinc/nickel-induced inflammatory response in vascular endothelial cells.

Toxicol Appl Pharmacol 2013 Dec 29;273(3):492-9. Epub 2013 Sep 29.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli 350, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2013.09.014DOI Listing
December 2013

Pulmonary CYP2A13 levels are associated with early occurrence of lung cancer-Its implication in mutagenesis of non-small cell lung carcinoma.

Cancer Epidemiol 2013 Oct 7;37(5):653-9. Epub 2013 Jun 7.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.

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http://dx.doi.org/10.1016/j.canep.2013.04.010DOI Listing
October 2013

Use of a highly sensitive recombinant hepatoma cell method to determine dioxin concentrations in samples of fish and crab from a hotspot area.

Environ Sci Process Impacts 2013 Jun;15(6):1264-70

Emerging Compounds Research Center, Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, No. 1, Hseuh Fu Road, Neipu, Pingtung County 912, Taiwan.

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http://dx.doi.org/10.1039/c3em30935eDOI Listing
June 2013

Size distribution of airborne fungi in vehicles under various driving conditions.

Arch Environ Occup Health 2013 ;68(2):95-100

Department of Bioenvironmental Engineering, Chung Yuan Christian University, Chung-Li, Taiwan.

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http://dx.doi.org/10.1080/19338244.2011.650798DOI Listing
April 2013

Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.

Respiration 2012 11;84(4):319-26. Epub 2012 Aug 11.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1159/000339591DOI Listing
March 2013

An improved AhR reporter gene assay for analyzing dioxins in soil, sediment and fish.

Bull Environ Contam Toxicol 2012 Oct 12;89(4):739-43. Epub 2012 Aug 12.

Department of Environmental Science and Engineering, Emerging Compounds Research Center, National Pingtung University and Science and Technology, Neipu 912, Pingtung County, Taiwan.

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http://dx.doi.org/10.1007/s00128-012-0774-9DOI Listing
October 2012

Levels of breast milk PBDEs from southern Taiwan and their potential impact on neurodevelopment.

Pediatr Res 2011 Dec;70(6):596-600

Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Neipu, 912 Pingtung, Taiwan.

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http://dx.doi.org/10.1203/PDR.0b013e3182320b9bDOI Listing
December 2011

Neurodevelopment of infants with prenatal exposure to polybrominated diphenyl ethers.

Bull Environ Contam Toxicol 2011 Dec 28;87(6):643-8. Epub 2011 Sep 28.

Department of Pharmacy and Graduate Institute of Pharmaceutical Technology, Tajen University, Yanpu Pingtung County, 907, Taiwan.

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http://dx.doi.org/10.1007/s00128-011-0422-9DOI Listing
December 2011

Zinc induces chemokine and inflammatory cytokine release from human promonocytes.

J Hazard Mater 2011 Nov 19;196:335-41. Epub 2011 Sep 19.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli 350, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2011.09.035DOI Listing
November 2011

Zinc ions induce inflammatory responses in vascular endothelial cells.

Bull Environ Contam Toxicol 2011 Aug 26;87(2):113-6. Epub 2011 May 26.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan 350, Miaoli County, Taiwan.

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http://link.springer.com/content/pdf/10.1007/s00128-011-0317
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http://dx.doi.org/10.1007/s00128-011-0317-9DOI Listing
August 2011

Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach.

Toxicol Appl Pharmacol 2011 Jun 4;253(2):145-52. Epub 2011 Apr 4.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.

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http://dx.doi.org/10.1016/j.taap.2011.03.022DOI Listing
June 2011

Fast cleanup system combined with a dioxin-responsive element-driven luciferase bioassay for analysis of polychlorinated dibenzo-p-dioxins/furans in sediments and soils.

Bull Environ Contam Toxicol 2011 Mar 5;86(3):278-82. Epub 2011 Feb 5.

Department of Environmental Science and Engineering, Emerging Compounds Research Center, National Pingtung University and Science and Technology, Neipu 912, Pingtung County, Taiwan.

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http://dx.doi.org/10.1007/s00128-011-0205-3DOI Listing
March 2011

A recombinant peroxisome proliferator response element-driven luciferase assay for evaluation of potential environmental obesogens.

Biotechnol Lett 2010 Dec 28;32(12):1789-96. Epub 2010 Jul 28.

Department of Bioenvironmental Engineering, Chung Yuan Christian University, Chungli, 320, Taiwan.

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http://dx.doi.org/10.1007/s10529-010-0359-9DOI Listing
December 2010

Zinc oxide particles induce inflammatory responses in vascular endothelial cells via NF-κB signaling.

J Hazard Mater 2010 Nov 31;183(1-3):182-8. Epub 2010 Jul 31.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2010.07.010DOI Listing
November 2010

Impact of non-occupational exposure to polybrominated diphenyl ethers on menstruation characteristics of reproductive-age females.

Environ Int 2010 Oct 9;36(7):728-35. Epub 2010 Jun 9.

Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Neipu, 912 Pingtung County, Taiwan.

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http://dx.doi.org/10.1016/j.envint.2010.05.007DOI Listing
October 2010

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on adipogenic differentiation and insulin-induced glucose uptake in 3T3-L1 cells.

J Hazard Mater 2010 Oct 25;182(1-3):649-55. Epub 2010 Jun 25.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli County 35053, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2010.06.081DOI Listing
October 2010

Proliferation inhibition, DNA damage, and cell-cycle arrest of human astrocytoma cells after acrylamide exposure.

Chem Res Toxicol 2010 Sep;23(9):1449-58

Department of Veterinary Medicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 106, Taiwan.

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http://dx.doi.org/10.1021/tx1000893DOI Listing
September 2010

Effects of arecoline on adipogenesis, lipolysis, and glucose uptake of adipocytes-A possible role of betel-quid chewing in metabolic syndrome.

Toxicol Appl Pharmacol 2010 Jun 18;245(3):370-7. Epub 2010 Apr 18.

Laboratory of Molecular Toxicology, Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan.

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http://linkinghub.elsevier.com/retrieve/pii/S0041008X1000135
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http://dx.doi.org/10.1016/j.taap.2010.04.008DOI Listing
June 2010

The inhibition effect of 2,3,7,8-tetrachlorinated dibenzo-p-dioxin-induced aryl hydrocarbon receptor activation in human hepatoma cells with the treatment of cadmium chloride.

J Hazard Mater 2009 Oct 4;170(1):351-6. Epub 2009 May 4.

Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Neipu, Pingtung 912, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2009.04.090DOI Listing
October 2009

Acrylamide-induced astrogliotic and apoptotic responses in human astrocytoma cells.

Toxicol In Vitro 2009 Aug 6;23(5):855-61. Epub 2009 May 6.

Department of Veterinary Medicine, National Taiwan University, Taipei 106, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.tiv.2009.04.015DOI Listing
August 2009

Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.

Toxicol In Vitro 2009 Aug 24;23(5):897-905. Epub 2009 May 24.

Laboratory of Molecular Toxicology, Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli County 35053, Taiwan.

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http://dx.doi.org/10.1016/j.tiv.2009.05.009DOI Listing
August 2009

Emissions of polychlorinated dibenzo-p-dioxins and dibenzofurans from a heavy oil-fueled power plant in northern Taiwan.

J Hazard Mater 2009 Apr 6;163(1):266-72. Epub 2008 Jul 6.

Department of Bioenvironmental Engineering, Chung Yuan Christian University, Chung-Li 320, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2008.06.119DOI Listing
April 2009

Increased aquaglyceroporin 9 expression disrupts arsenic resistance in human lung cancer cells.

Toxicol In Vitro 2009 Mar 7;23(2):209-16. Epub 2008 Dec 7.

Laboratory of Molecular Toxicology, Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan, Miaoli County 35053, Taiwan.

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http://dx.doi.org/10.1016/j.tiv.2008.11.011DOI Listing
March 2009

Approach for energy saving and pollution reducing by fueling diesel engines with emulsified biosolution/ biodiesel/diesel blends.

Environ Sci Technol 2008 May;42(10):3849-55

Department of Chemical and Materials Engineering and Super Micro Mass Research & Technology Center, Cheng Shiu University, Kaohsiung County 833, Taiwan.

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http://dx.doi.org/10.1021/es702835nDOI Listing
May 2008

Arecoline inhibits the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cytochrome P450 1A1 activation in human hepatoma cells.

J Hazard Mater 2007 Jul 17;146(1-2):356-61. Epub 2006 Dec 17.

Laboratory of Molecular Toxicology, Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2006.12.035DOI Listing
July 2007

Glutathione regulation of redox-sensitive signals in tumor necrosis factor-alpha-induced vascular endothelial dysfunction.

Toxicol Appl Pharmacol 2007 Jun 23;221(2):168-78. Epub 2007 Mar 23.

Laboratory of Molecular Toxicology, Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan.

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http://dx.doi.org/10.1016/j.taap.2007.03.005DOI Listing
June 2007

ATM/ATR-related checkpoint signals mediate arsenite-induced G2/M arrest in primary aortic endothelial cells.

Arch Toxicol 2006 Dec;80(12):804-10

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan.

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http://link.springer.com/10.1007/s00204-006-0110-4
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http://dx.doi.org/10.1007/s00204-006-0110-4DOI Listing
December 2006

Arsenic inhibits induction of cytochrome P450 1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human hepatoma cells.

J Hazard Mater 2006 Sep 25;137(2):716-22. Epub 2006 Apr 25.

Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.

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http://dx.doi.org/10.1016/j.jhazmat.2006.03.053DOI Listing
September 2006

Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells.

Arch Toxicol 2006 Jun 19;80(6):310-8. Epub 2005 Nov 19.

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 35 Keyan Road, Miaoli County 350, Zhunan Town, Taiwan.

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http://dx.doi.org/10.1007/s00204-005-0045-1DOI Listing
June 2006

Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway.

Toxicol Sci 2006 Mar 7;90(1):73-86. Epub 2005 Dec 7.

Molecular Anticancer Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, Hualien, Taiwan.

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http://dx.doi.org/10.1093/toxsci/kfj070DOI Listing
March 2006

Arsenite induces endothelial cytotoxicity by down-regulation of vascular endothelial nitric oxide synthase.

Toxicol Appl Pharmacol 2005 Nov;208(3):277-84

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.taap.2005.03.001DOI Listing
November 2005

Arsenite enhances tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1.

Toxicol Appl Pharmacol 2005 Nov;209(1):10-8

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.taap.2005.03.006DOI Listing
November 2005

Inhibition of alpha7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells.

Toxicol Lett 2005 Oct;159(1):47-59

Molecular Toxicology Laboratory, Institute of Pharmacology and Toxicology, College of Life Sciences, Tzu Chi University, 701 Section 3, Hualien 970, Taiwan.

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http://dx.doi.org/10.1016/j.toxlet.2005.04.012DOI Listing
October 2005

The protective role of intracellular GSH status in the arsenite-induced vascular endothelial dysfunction.

Chem Res Toxicol 2004 Feb;17(2):208-17

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Kaohsiung, Taiwan, Republic of China.

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http://dx.doi.org/10.1021/tx034202vDOI Listing
February 2004

Stent implantation activates Akt in the vessel wall: role of mechanical stretch in vascular smooth muscle cells.

Arterioscler Thromb Vasc Biol 2003 Nov 11;23(11):2015-20. Epub 2003 Sep 11.

Division of Biomedical Sciences, University of California, Riverside, Riverside, Calif 92521-0121, USA.

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http://dx.doi.org/10.1161/01.ATV.0000095161.06906.EDDOI Listing
November 2003

The protective role of NF-kappaB and AP-1 in arsenite-induced apoptosis in aortic endothelial cells.

Toxicol Appl Pharmacol 2003 Sep;191(2):177-87

Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Medical Research Building/Room 108, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/s0041-008x(03)00239-4DOI Listing
September 2003

Roles of microtubule dynamics and small GTPase Rac in endothelial cell migration and lamellipodium formation under flow.

J Vasc Res 2002 Nov-Dec;39(6):465-76

Department of Bioengineering, Whitaker Institute of Biomedical Engineering, University of California-San Diego, La Jolla, CA 92093-0427, USA.

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http://dx.doi.org/10.1159/000067202DOI Listing
March 2003

Genomic analysis of smooth muscle cells in 3-dimensional collagen matrix.

FASEB J 2003 Jan 15;17(1):97-9. Epub 2002 Nov 15.

Department of Bioengineering and The Whitaker Institute of Biomedical Engineering University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1096/fj.02-0256fjeDOI Listing
January 2003

Induction of apoptosis in vascular smooth muscle cells by mechanical stretch.

Am J Physiol Heart Circ Physiol 2002 May;282(5):H1709-16

Department of Bioengineering and Whitaker Institute of Biomedical Engineering, Advanced Tissue Sciences, La Jolla, California 92093, USA.

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http://ajpheart.physiology.org/content/ajpheart/282/5/H1709.
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http://ajpheart.physiology.org/lookup/doi/10.1152/ajpheart.0
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http://dx.doi.org/10.1152/ajpheart.00744.2001DOI Listing
May 2002

Rate sensitivity of shear-induced changes in the lateral diffusion of endothelial cell membrane lipids: a role for membrane perturbation in shear-induced MAPK activation.

FASEB J 2002 Feb 14;16(2):216-8. Epub 2001 Dec 14.

Department of Bioengineering and The Whitaker Institute of Biomedical Engineering, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1096/fj.01-0434fjeDOI Listing
February 2002