Publications by authors named "Tryfon Zarganes-Tzitzikas"

24 Publications

  • Page 1 of 1

Multicomponent reaction-derived covalent inhibitor space.

Sci Adv 2021 Feb 3;7(6). Epub 2021 Feb 3.

Department of Drug Design, University of Groningen, A. Deusinglaan 1, 9700 AD Groningen, The Netherlands.

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February 2021

Multicomponent Reactions: "Kinderleicht".

J Chem Educ 2020 Oct 31;97(10):3739-3745. Epub 2020 Aug 31.

Drug Design Group, Department of Pharmacy, University of Groningen, A. Deusinglaan 1, Groningen 9700 AV, The Netherlands.

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October 2020

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.

Immunology 2021 Jan 30;162(1):84-91. Epub 2020 Oct 30.

Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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January 2021

[F]Atorvastatin: synthesis of a potential molecular imaging tool for the assessment of statin-related mechanisms of action.

EJNMMI Res 2020 Apr 15;10(1):34. Epub 2020 Apr 15.

Department of Nuclear Medicine and Molecular Imaging - University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713, GZ, Groningen, The Netherlands.

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April 2020

Late-Stage Copper-Catalyzed Radiofluorination of an Arylboronic Ester Derivative of Atorvastatin.

Molecules 2019 Nov 20;24(23). Epub 2019 Nov 20.

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

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November 2019

MCR Scaffolds Get Hotter with F-Labeling.

Molecules 2019 Apr 4;24(7). Epub 2019 Apr 4.

Department of Drug Design, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV Groningen, The Netherlands.

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April 2019

Atorvastatin (Lipitor) by MCR.

ACS Med Chem Lett 2019 Mar 7;10(3):389-392. Epub 2019 Feb 7.

Department of Pharmacy, Drug Design group, University of Groningen, A. Deusinglaan 1, Groningen 9700 AV, The Netherlands.

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March 2019

Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists.

Beilstein J Org Chem 2019 20;15:513-520. Epub 2019 Feb 20.

Department of Drug Design, University of Groningen, Antonius Deusinglaan 1, 9700 AD Groningen, The Netherlands.

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February 2019

Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR.

ACS Comb Sci 2018 04 26;20(4):192-196. Epub 2018 Feb 26.

University of Groningen , Department of Drug Design , A. Deusinglaan 1 , 9713 AV Groningen , The Netherlands.

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April 2018

Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies?

Angew Chem Int Ed Engl 2018 04 23;57(18):4840-4848. Epub 2018 Feb 23.

Department of Drug Design, University of Groningen, A. Deusinglaan 1, 9713, AV, Groningen, The Netherlands.

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April 2018

Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.

Angew Chem Int Ed Engl 2017 10 26;56(44):13732-13735. Epub 2017 Sep 26.

Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland.

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October 2017

Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).

Expert Opin Ther Pat 2016 Sep 6;26(9):973-7. Epub 2016 Jul 6.

a Department of Drug Design , University of Groningen , Groningen , The Netherlands.

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September 2016

Multicomponent Reactions, Union of MCRs and Beyond.

Chem Rec 2015 Oct 11;15(5):981-96. Epub 2015 Sep 11.

Department of Drug Design, University of Groningen, The Netherlands.

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October 2015

Leuckart-Wallach Route Toward Isocyanides and Some Applications.

ACS Comb Sci 2015 Sep 10;17(9):493-9. Epub 2015 Aug 10.

Department of Drug Design, University of Gröningen , A. Deusinglaan 1, Gröningen 9700AV, The Netherlands.

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September 2015

Concise Synthesis of Tetrazole-keto-piperazines by Two Consecutive Ugi Reactions.

European J Org Chem 2015 Jan 17;2015(1):51-55. Epub 2014 Nov 17.

Department of Drug Design, University of Groningen, Antonius Deusinglaan 1, Postbus 196, 9700 AD Groningen, Netherlands, Homepage: www.drugdesign.nl.

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January 2015

One-pot five-component synthesis of spirocyclopenta[b]chromene derivatives and their acid-catalyzed rearrangement.

J Org Chem 2012 Oct 28;77(20):9018-28. Epub 2012 Sep 28.

Department of Chemistry, Laboratory of Organic Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.

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October 2012

One-pot synthesis of functionalized spirobenzofuranones via MCR involving 3-cyanochromones.

J Org Chem 2011 Nov 12;76(21):9008-14. Epub 2011 Oct 12.

Department of Chemistry, Laboratory of Organic Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.

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November 2011

Synthesis of 2-keto-imidazoles utilizing N-arylamino-substituted N-heterocyclic carbenes.

J Org Chem 2011 Mar 20;76(5):1468-71. Epub 2011 Jan 20.

Department of Chemistry, Laboratory of Organic Chemistry, University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.

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March 2011