Troy A Markel

Troy A Markel

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Troy A Markel

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Sildenafil as a Rescue Agent Following Intestinal Ischemia and Reperfusion Injury.

J Surg Res 2020 02 17;246:512-518. Epub 2019 Oct 17.

The Indiana University School of Medicine, Indiana University Health, Indianapolis, Indiana; Department of Surgery, Section of Pediatric Surgery, Indiana University Health, Indianapolis, Indiana; Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2019.09.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917919PMC
February 2020

Are surgeons behind the scientific eight ball: Delayed acquisition of the NIH K08 mentored career development award.

Am J Surg 2020 Feb 31;219(2):366-371. Epub 2019 Dec 31.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.amjsurg.2019.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024027PMC
February 2020

Lung biopsy in children's interstitial and diffuse lung disease: Does it alter management?

Pediatr Pulmonol 2020 Feb 10. Epub 2020 Feb 10.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1002/ppul.24683DOI Listing
February 2020

Practice patterns in imaging guidance for ECMO cannulation: A survey of the American Pediatric Surgical Association.

J Pediatr Surg 2019 Nov 29. Epub 2019 Nov 29.

Department of Surgery, Indiana University School of Medicine, Emerson Hall 545 Barnhill Drive, Room 125, Indianapolis, IN 46202; Department of Surgery, Section of Pediatric Surgery, 705 Riley Hospital Dr. RI 2500, Indianapolis, IN 46202. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2019.11.010DOI Listing
November 2019

Analyzing ICU Patient Room Environmental Quality Through Unoccupied, Normal, and Emergency Procedure Modes: An EQI Evaluation.

HERD 2019 Oct 10;12(4):217-225. Epub 2019 Jun 10.

Geist Medical Consulting, LLC, Indianapolis, IN, USA.

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http://dx.doi.org/10.1177/1937586719854218DOI Listing
October 2019

Mesenchymal stem cells promote mesenteric vasodilation through hydrogen sulfide and endothelial nitric oxide.

Am J Physiol Gastrointest Liver Physiol 2019 Oct 25;317(4):G441-G446. Epub 2019 Jul 25.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1152/ajpgi.00132.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842994PMC
October 2019

Extended hypoxia-mediated H S production provides for long-term oxygen sensing.

Acta Physiol (Oxf) 2019 Aug 23:e13368. Epub 2019 Aug 23.

Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.

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http://dx.doi.org/10.1111/apha.13368DOI Listing
August 2019

Interleukin-6 Therapy Improves Intestinal Recovery Following Ischemia.

J Surg Res 2019 07 1;239:142-148. Epub 2019 Mar 1.

Department of Surgery, Section of Pediatric Surgery, Indianapolis, Indiana; The Indiana University School of Medicine, Indianapolis, Indiana; Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2019.02.001DOI Listing
July 2019

Inhibiting hydrogen sulfide production in umbilical stem cells reduces their protective effects during experimental necrotizing enterocolitis.

J Pediatr Surg 2019 Jun 1;54(6):1168-1173. Epub 2019 Mar 1.

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indianapolis, IN; The Indiana University School of Medicine, Indianapolis, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.jpedsurg.2019.02.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545254PMC
June 2019

Biobanking for necrotizing enterocolitis: Needs and standards.

J Pediatr Surg 2019 May 11. Epub 2019 May 11.

Department of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842670PMC
May 2019

Hydrogen Sulfide Donor GYY4137 Acts Through Endothelial Nitric Oxide to Protect Intestine in Murine Models of Necrotizing Enterocolitis and Intestinal Ischemia.

J Surg Res 2019 02 23;234:294-302. Epub 2018 Oct 23.

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana; Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2018.08.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291834PMC
February 2019

Comparison of operating room air distribution systems using the environmental quality indicator method of dynamic simulated surgical procedures.

Am J Infect Control 2019 01 18;47(1):e1-e6. Epub 2018 Sep 18.

Geist Medical Consulting LLC, Indiana University Health, Riley Hospital for Children, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.ajic.2018.07.020DOI Listing
January 2019

Accounting for early job turnover in recent pediatric surgery fellowship graduates: An American Pediatric Surgical Association Membership and Credentials Committee study.

J Pediatr Surg 2018 Nov 27;53(11):2273-2278. Epub 2018 Apr 27.

Department of Surgery, Indiana University Health, Indianapolis, IN; Section of Pediatric Surgery, Riley Hospital for Children, Indianapolis, IN. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2018.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186502PMC
November 2018

Covering the instrument table decreases bacterial bioburden: An evaluation of environmental quality indicators.

Am J Infect Control 2018 10 11;46(10):1127-1133. Epub 2018 May 11.

Onsite-LLC, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.ajic.2018.02.032DOI Listing
October 2018

Hydrogen sulfide provides intestinal protection during a murine model of experimental necrotizing enterocolitis.

J Pediatr Surg 2018 Sep 24;53(9):1692-1698. Epub 2017 Dec 24.

Department of Surgery, Section of Pediatric Surgery, Indianapolis, IN; Riley Hospital for Children at Indiana University Health, Indianapolis, IN; The Indiana University School of Medicine, Indianapolis, IN. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2017.12.003DOI Listing
September 2018

Loss of endothelial nitric oxide synthase exacerbates intestinal and lung injury in experimental necrotizing enterocolitis.

J Pediatr Surg 2018 Jun 8;53(6):1208-1214. Epub 2018 Mar 8.

Department of Surgery, Section of Pediatric Surgery, Indianapolis, IN; Riley Hospital for Children at Indiana University Health, Indianapolis, IN; The Indiana University School of Medicine, Indianapolis, IN. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994357PMC
June 2018

The route and timing of hydrogen sulfide therapy critically impacts intestinal recovery following ischemia and reperfusion injury.

J Pediatr Surg 2018 Jun 6;53(6):1111-1117. Epub 2018 Mar 6.

Department of Surgery, Section of Pediatric Surgery, Indianapolis, IN; Riley Hospital for Children at Indiana University Health, Indianapolis, IN; The Indiana University School of Medicine, Indianapolis, IN. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994359PMC
June 2018

Why wait: early enteral feeding after pediatric gastrostomy tube placement.

J Pediatr Surg 2018 Apr 27;53(4):656-660. Epub 2017 Jun 27.

Department of Surgery, Division of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indianapolis, IN. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2017.06.015DOI Listing
April 2018

Wearing long sleeves while prepping a patient in the operating room decreases airborne contaminants.

Am J Infect Control 2018 04 6;46(4):369-374. Epub 2017 Dec 6.

Prism Environmental Health and Safety, Discovery Bay, CA.

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http://dx.doi.org/10.1016/j.ajic.2017.10.016DOI Listing
April 2018

Umbilical mesenchymal stromal cells provide intestinal protection through nitric oxide dependent pathways.

J Surg Res 2018 04 28;224:148-155. Epub 2017 Dec 28.

Section of Pediatric Surgery, Department of Surgery, Indianapolis, Indiana; The Indiana University School of Medicine, Indianapolis, Indiana; Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2017.11.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128694PMC
April 2018

Preface: The NEC Society.

Semin Pediatr Surg 2018 Feb 7;27(1):1-2. Epub 2017 Nov 7.

Department of Pediatrics, Division of Neonatology, University of California Davis School of Medicine, Sacramento, California.

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http://dx.doi.org/10.1053/j.sempedsurg.2017.11.001DOI Listing
February 2018

Stem cell therapy in necrotizing enterocolitis: Current state and future directions.

Semin Pediatr Surg 2018 Feb 7;27(1):57-64. Epub 2017 Nov 7.

Department of Surgery, Section of Pediatric Surgery, Indiana University School of Medicine, Riley Hospital for Children at IU Health, 705 Riley Hospital Dr. RI 2500, Indianapolis, Indiana 46202. Electronic address:

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http://dx.doi.org/10.1053/j.sempedsurg.2017.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745058PMC
February 2018

Physical Examination is the Best Predictor of the Need for Abdominal Surgery in Children Following Motor Vehicle Collision.

J Emerg Med 2018 01 6;54(1):1-7. Epub 2017 Nov 6.

Indiana University School of Medicine, Section of Pediatric Surgery, Indianapolis, Indiana; Riley Hospital for Children, Indiana University Health, Section of Pediatric Surgery, Indianapolis, Indiana; Department of Surgery, Section of Pediatric Surgery, Indianapolis, Indiana.

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https://linkinghub.elsevier.com/retrieve/pii/S07364679173071
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http://dx.doi.org/10.1016/j.jemermed.2017.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865640PMC
January 2018

Management of Peritoneal Dialysis Catheters That Erode Into Bowel: Two Pediatric Case Reports and a Review of the Literature.

Perit Dial Int 2016 11-12;36(6):680-684

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health and The Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.3747/pdi.2016.00029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174877PMC
December 2017

Cost-benefit analysis of different air change rates in an operating room environment.

Am J Infect Control 2017 Dec 12;45(12):1318-1323. Epub 2017 Oct 12.

Prism Environmental Health and Safety, Discovery Bay, CA.

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http://dx.doi.org/10.1016/j.ajic.2017.07.024DOI Listing
December 2017

Hydrogen Sulfide: A Potential Novel Therapy for the Treatment of Ischemia.

Shock 2017 11;48(5):511-524

*Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana †Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana ‡Department of Pediatrics, Section of Neonatology, Indiana University School of Medicine, Indianapolis, Indiana §Department of Physiology, Indiana University School of Medicine, South Bend, Indiana.

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http://dx.doi.org/10.1097/SHK.0000000000000894DOI Listing
November 2017

Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications.

Transl Res 2017 11 22;189:1-12. Epub 2017 Jul 22.

Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Ind; Department of Cellular & Integrative Physiology, Indiana University School of Medicine, Indianapolis, Ind; Indianapolis Veterans Affairs Medical Center, Indianapolis, Ind. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2017.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659947PMC
November 2017

The utility of presacral drainage in penetrating rectal injuries in adult and pediatric patients.

J Surg Res 2017 11 7;219:279-287. Epub 2017 Jul 7.

Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2017.05.056DOI Listing
November 2017

Endangered academia: preserving the pediatric surgeon scientist.

J Pediatr Surg 2017 Jul 20;52(7):1079-1083. Epub 2016 Dec 20.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202.

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https://linkinghub.elsevier.com/retrieve/pii/S00223468163064
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http://dx.doi.org/10.1016/j.jpedsurg.2016.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059369PMC
July 2017

Direct peritoneal resuscitation improves mesenteric perfusion by nitric oxide dependent pathways.

J Surg Res 2017 06 4;213:274-280. Epub 2017 Mar 4.

Section of Pediatric Surgery, Department of Surgery, Indiana University School of Medicine, Riley Hospital for Children and Indiana University Health, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2017.02.060DOI Listing
June 2017

Hydrogen sulfide improves intestinal recovery following ischemia by endothelial nitric oxide-dependent mechanisms.

Am J Physiol Gastrointest Liver Physiol 2017 May 9;312(5):G450-G456. Epub 2017 Mar 9.

Section of Pediatric Surgery, Department of Surgery, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana;

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http://dx.doi.org/10.1152/ajpgi.00444.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451562PMC
May 2017

A randomized trial to assess advancement of enteral feedings following surgery for hypertrophic pyloric stenosis.

J Pediatr Surg 2017 Apr 14;52(4):534-539. Epub 2016 Oct 14.

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health and The Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.jpedsurg.2016.09.069DOI Listing
April 2017

Methodology for analyzing environmental quality indicators in a dynamic operating room environment.

Am J Infect Control 2017 Apr 21;45(4):354-359. Epub 2016 Dec 21.

ARTEC Environmental Monitoring, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.ajic.2016.11.001DOI Listing
April 2017

Mesenchymal stromal cell therapy for the treatment of intestinal ischemia: Defining the optimal cell isolate for maximum therapeutic benefit.

Cytotherapy 2016 12 10;18(12):1457-1470. Epub 2016 Oct 10.

Department of Surgery, Indiana University Health, Indianapolis, IN, USA; The Indiana University School of Medicine, Indianapolis, IN, USA; Section of Pediatric Surgery, Indiana University Health, Indianapolis, IN, USA; Riley Hospital for Children, Indiana University Health, Indianapolis, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2016.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111869PMC
December 2016

Harvest tissue source does not alter the protective power of stromal cell therapy after intestinal ischemia and reperfusion injury.

J Surg Res 2016 08 11;204(2):361-370. Epub 2016 May 11.

Department of Surgery, Section of Pediatric Surgery, Indianapolis, Indiana; Indiana University School of Medicine, Indianapolis, Indiana; Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2016.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002874PMC
August 2016

Human Adipose Stromal Cells Increase Survival and Mesenteric Perfusion Following Intestinal Ischemia and Reperfusion Injury.

Shock 2016 07;46(1):75-82

*Department of Surgery †Section of Pediatric Surgery ‡Department of Cellular and Integrative Physiology §Department of Medicine, Indiana Center for Vascular Biology and Medicine ¶Department of Pediatrics, Section of Neonatology ||Riley Hospital for Children at Indiana University Health #Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1097/SHK.0000000000000571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905779PMC
July 2016

Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation.

Case Rep Oncol Med 2016 26;2016:3179147. Epub 2016 Jun 26.

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1155/2016/3179147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939191PMC
July 2016

Direct peritoneal resuscitation improves survival and decreases inflammation after intestinal ischemia and reperfusion injury.

J Surg Res 2015 Dec 18;199(2):428-34. Epub 2015 Jun 18.

Section of Pediatric Surgery, Department of Surgery, Riley Hospital for Children at Indiana University Health and, The Indiana University School of Medicine, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2015.06.031DOI Listing
December 2015

Human mesenchymal stromal cells decrease mortality after intestinal ischemia and reperfusion injury.

J Surg Res 2015 Nov 2;199(1):56-66. Epub 2015 Jul 2.

Section of Neonatology, Department of Pediatrics, Riley Hospital for Children at Indiana University Health, The Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1016/j.jss.2015.06.060DOI Listing
November 2015

Environmental pesticides increase the risk of developing hypertrophic pyloric stenosis.

J Pediatr Surg 2015 Aug 17;50(8):1283-8. Epub 2014 Dec 17.

Neonatology, Indiana University School of Medicine/Riley Hospital, Indianapolis, IN, United States.

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http://dx.doi.org/10.1016/j.jpedsurg.2014.12.009DOI Listing
August 2015

A survey of the pediatric surgery program directors: optimizing resident research to make pediatric surgery training more efficient.

J Pediatr Surg 2015 Jun 14;50(6):1053-7. Epub 2015 Mar 14.

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.jpedsurg.2015.03.038DOI Listing
June 2015

Vascular endothelial growth factor: therapeutic possibilities and challenges for the treatment of ischemia.

Cytokine 2015 Feb 18;71(2):385-93. Epub 2014 Sep 18.

Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, Indianapolis, IN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2014.08.005DOI Listing
February 2015

Predicting disease severity of necrotizing enterocolitis: how to identify infants for future novel therapies.

J Clin Neonatol 2014 Jan;3(1):1-9

Department of Pediatrics, Section of Neonatology, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.4103/2249-4847.128717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982330PMC
January 2014

Bronchogenic/foregut cyst of the ileal mesentery in a child mimicking ovarian mass.

Fetal Pediatr Pathol 2013 Oct 25;32(5):357-61. Epub 2013 Feb 25.

Department of Pediatric Surgery, Indiana University School of Medicine and Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.

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http://www.tandfonline.com/doi/full/10.3109/15513815.2013.76
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http://dx.doi.org/10.3109/15513815.2013.768742DOI Listing
October 2013

A review of postoperative feeding regimens in infantile hypertrophic pyloric stenosis.

J Pediatr Surg 2013 Oct;48(10):2175-9

Indiana University School of Medicine, Indianapolis, IN, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00223468130039
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http://dx.doi.org/10.1016/j.jpedsurg.2013.04.023DOI Listing
October 2013

Gastric pneumatosis secondary to pyloric stenosis.

J Pediatr Surg 2013 Mar;48(3):655-7

Department of Pediatric Surgery, Indiana University School of Medicine and Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana.

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http://dx.doi.org/10.1016/j.jpedsurg.2012.12.018DOI Listing
March 2013

MEK, p38, and PI-3K mediate cross talk between EGFR and TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells.

Am J Physiol Cell Physiol 2009 Nov 19;297(5):C1284-93. Epub 2009 Aug 19.

Departments of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1152/ajpcell.00183.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777403PMC
November 2009

Proinflammatory stem cell signaling in cardiac ischemia.

Antioxid Redox Signal 2009 Aug;11(8):1883-96

Clarian Cardiovascular Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1089/ars.2009.2434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872207PMC
August 2009

Stem cells in sepsis.

Ann Surg 2009 Jul;250(1):19-27

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/SLA.0b013e3181a77b9cDOI Listing
July 2009

The utility of computed tomography as a screening tool for the evaluation of pediatric blunt chest trauma.

J Trauma 2009 Jul;67(1):23-8

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/TA.0b013e318184ba9aDOI Listing
July 2009

Estradiol-treated mesenchymal stem cells improve myocardial recovery after ischemia.

J Surg Res 2009 Apr 13;152(2):319-24. Epub 2008 Mar 13.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1016/j.jss.2008.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785180PMC
April 2009

Angiopoietin-1 in the treatment of ischemia and sepsis.

Shock 2009 Apr;31(4):335-41

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/SHK.0b013e3181862c63DOI Listing
April 2009

Are neonatal stem cells as effective as adult stem cells in providing ischemic protection?

J Surg Res 2009 Apr 28;152(2):325-30. Epub 2008 Apr 28.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1016/j.jss.2008.03.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929583PMC
April 2009

Role of tumor necrosis factor receptor 1 in sex differences of stem cell mediated cardioprotection.

Ann Thorac Surg 2009 Mar;87(3):812-9

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1016/j.athoracsur.2008.12.033DOI Listing
March 2009

beta-Blockers in sepsis: reexamining the evidence.

Shock 2009 Feb;31(2):113-9

Departments of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1097/SHK.0b013e318180ffb6DOI Listing
February 2009

Exogenous estrogen rapidly attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction.

Shock 2008 Dec;30(6):660-7

Division of Pulmonary, Allergy, Critical Care and Occupational Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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https://insights.ovid.com/crossref?an=00024382-200812000-000
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http://dx.doi.org/10.1097/SHK.0b013e31816f239fDOI Listing
December 2008

Vascular endothelial growth factor improves myocardial functional recovery following ischemia/reperfusion injury.

J Surg Res 2008 Dec 16;150(2):286-92. Epub 2008 Jan 16.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00224804070239
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http://dx.doi.org/10.1016/j.jss.2007.12.772DOI Listing
December 2008

Females exhibit relative resistance to depressive effects of tumor necrosis factor-alpha on the myocardium.

J Surg Res 2008 Nov 17;150(1):92-9. Epub 2008 Jan 17.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1016/j.jss.2007.12.777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586947PMC
November 2008

Selective estrogen receptor-alpha and estrogen receptor-beta agonists rapidly decrease pulmonary artery vasoconstriction by a nitric oxide-dependent mechanism.

Am J Physiol Regul Integr Comp Physiol 2008 Nov 1;295(5):R1486-93. Epub 2008 Oct 1.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1152/ajpregu.90667.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584849PMC
November 2008

TNFR1 signaling resistance associated with female stem cell cytokine production is independent of TNFR2-mediated pathways.

Am J Physiol Regul Integr Comp Physiol 2008 Oct 6;295(4):R1124-30. Epub 2008 Aug 6.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://www.physiology.org/doi/10.1152/ajpregu.90508.2008
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http://dx.doi.org/10.1152/ajpregu.90508.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576085PMC
October 2008

TGF-alpha increases human mesenchymal stem cell-secreted VEGF by MEK- and PI3-K- but not JNK- or ERK-dependent mechanisms.

Am J Physiol Regul Integr Comp Physiol 2008 Oct 6;295(4):R1115-23. Epub 2008 Aug 6.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576096PMC
October 2008

Steroids and poor nutrition are associated with infectious wound complications in children undergoing first stage procedures for ulcerative colitis.

Surgery 2008 Oct;144(4):540-5; discussion 545-7

Department of Surgery, J. W. Riley Hospital for Children, Indiana University, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1016/j.surg.2008.07.005DOI Listing
October 2008

Proestrus female rats are more resistant to right ventricular pressure overload.

Shock 2008 Sep;30(3):318-23

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1097/SHK.0b013e318164e981DOI Listing
September 2008

Stem cell therapy in myocardial repair and remodeling.

J Am Coll Surg 2008 Sep 19;207(3):423-34. Epub 2008 May 19.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.jamcollsurg.2008.04.013DOI Listing
September 2008

Mechanisms of sex differences in TNFR2-mediated cardioprotection.

Circulation 2008 Sep;118(14 Suppl):S38-45

Departments of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.756890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655136PMC
September 2008

Differential IL-6 and VEGF secretion in adult and neonatal mesenchymal stem cells: role of NFkB.

Cytokine 2008 Aug 14;43(2):215-9. Epub 2008 Jul 14.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.cyto.2008.05.015DOI Listing
August 2008

Interleukin 18 in the heart.

Shock 2008 Jul;30(1):3-10

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/SHK.0b013e318160f215DOI Listing
July 2008

Postischemic infusion of 17-beta-estradiol protects myocardial function and viability.

J Surg Res 2008 May 20;146(2):218-24. Epub 2007 Jul 20.

Department of Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 203, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.jss.2007.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390775PMC
May 2008

The right heart and its distinct mechanisms of development, function, and failure.

J Surg Res 2008 May 26;146(2):304-13. Epub 2007 Nov 26.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1016/j.jss.2007.04.003DOI Listing
May 2008

Deleterious effects of endogenous and exogenous testosterone on mesenchymal stem cell VEGF production.

Am J Physiol Regul Integr Comp Physiol 2008 May 12;294(5):R1498-503. Epub 2008 Mar 12.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1152/ajpregu.00897.2007DOI Listing
May 2008

Neonatal stem cells exhibit specific characteristics in function, proliferation, and cellular signaling that distinguish them from their adult counterparts.

Am J Physiol Regul Integr Comp Physiol 2008 May 2;294(5):R1491-7. Epub 2008 Apr 2.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1152/ajpregu.00031.2008DOI Listing
May 2008

Surgically relevant aspects of stem cell paracrine effects.

Surgery 2008 May 30;143(5):577-81. Epub 2008 Jan 30.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Ind, USA.

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http://dx.doi.org/10.1016/j.surg.2007.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387075PMC
May 2008

Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism.

Am J Physiol Cell Physiol 2008 Mar 30;294(3):C675-82. Epub 2008 Jan 30.

Departments of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1152/ajpcell.00437.2007DOI Listing
March 2008

Right ventricular TNF resistance during endotoxemia: the differential effects on ventricular function.

Am J Physiol Regul Integr Comp Physiol 2007 Nov 22;293(5):R1893-7. Epub 2007 Aug 22.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1152/ajpregu.00359.2007DOI Listing
November 2007

Stem cell mechanisms and paracrine effects: potential in cardiac surgery.

Shock 2007 Oct;28(4):375-83

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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October 2007

Activation of individual tumor necrosis factor receptors differentially affects stem cell growth factor and cytokine production.

Am J Physiol Gastrointest Liver Physiol 2007 Oct 19;293(4):G657-62. Epub 2007 Jul 19.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1152/ajpgi.00230.2007DOI Listing
October 2007

Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: the effects of sex and menstrual cycle.

Am J Physiol Endocrinol Metab 2007 Sep 26;293(3):E865-71. Epub 2007 Jun 26.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.00201.2007
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September 2007

In the adult mesenchymal stem cell population, source gender is a biologically relevant aspect of protective power.

Surgery 2007 Aug;142(2):215-21

Department of Surgery, Indiana University School of Medicine, Indianapolis, Ind, USA.

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August 2007

Management of gastrointestinal disorders in the bariatric patient.

Med Clin North Am 2007 May;91(3):443-50, xi

Department of Surgery, Indiana University School of Medicine, 545 Barnhill Drive, EH202, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1016/j.mcna.2007.01.004DOI Listing
May 2007

Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: the roles of p38, ERK, and JNK MAPK signaling.

Am J Physiol Gastrointest Liver Physiol 2007 Apr 4;292(4):G958-63. Epub 2007 Jan 4.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1152/ajpgi.00502.2006DOI Listing
April 2007

The struggle for iron: gastrointestinal microbes modulate the host immune response during infection.

J Leukoc Biol 2007 Feb;81(2):393-400

Department of Surgery, Indiana University School of Medicine, Emerson Hall 215, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1189/jlb.0906579DOI Listing
February 2007

Gender differences in injury induced mesenchymal stem cell apoptosis and VEGF, TNF, IL-6 expression: role of the 55 kDa TNF receptor (TNFR1).

J Mol Cell Cardiol 2007 Jan 30;42(1):142-9. Epub 2006 Oct 30.

Department of Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 215, Indianapolis, IN 46202, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002228280600923
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http://dx.doi.org/10.1016/j.yjmcc.2006.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779905PMC
January 2007

Therapeutic concepts for hypoxic pulmonary vasoconstriction involving ion regulation and the smooth muscle contractile apparatus.

J Mol Cell Cardiol 2006 Jun 11;40(6):751-60. Epub 2006 May 11.

Sections of General and Cardiothoracic Surgery, Department of Surgery, Indiana University Medical Center, Indianapolis, IN 46202, USA.

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June 2006

Cytokines in necrotizing enterocolitis.

Shock 2006 Apr;25(4):329-37

Department of Surgery, Indiana University School of Medicine, the Indiana Center for Vascular Biology and Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1097/01.shk.0000192126.33823.87DOI Listing
April 2006

Stem cell transplantation as a therapeutic approach to organ failure.

J Surg Res 2005 Nov 19;129(1):152-60. Epub 2005 Jul 19.

Section of Cardiothoracic Surgery, Department of Surgery, Indianapolis, Indiana 46202, USA.

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November 2005

Sex differences in the myocardial inflammatory response to acute injury.

Shock 2005 Jan;23(1):1-10

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 42602, USA.

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http://dx.doi.org/10.1097/01.shk.0000148055.12387.15DOI Listing
January 2005

Aging and the exercise pressor reflex in humans.

Circulation 2003 Feb;107(5):675-8

Cardiology Division, Penn State College of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1161/01.cir.0000055190.81716.abDOI Listing
February 2003