Publications by authors named "Toshihiro Oguma"

19Publications

Clinical safety, tolerability, pharmacokinetics and pharmacodynamics of the novel factor Xa inhibitor DY-807f in healthy volunteers.

Thromb Res 2015 Apr 4;135(4):594-601. Epub 2015 Jan 4.

Daiichi Sankyo RD Novare Co., Ltd., 1-16-13, Kitakasai, Edogawa-ku Tokyo 134-8630, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.thromres.2014.12.028DOI Listing
April 2015

Enzyme replacement therapy in newborn mucopolysaccharidosis IVA mice: early treatment rescues bone lesions?

Mol Genet Metab 2015 Feb 4;114(2):195-202. Epub 2014 Jun 4.

Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymgme.2014.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256128PMC
February 2015

Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans.

Drug Metab Dispos 2012 Dec 30;40(12):2250-5. Epub 2012 Aug 30.

Daiichi Sankyo Pharma Development, Edison, New Jersey, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.112.046888DOI Listing
December 2012

Enhancement of drug delivery: enzyme-replacement therapy for murine Morquio A syndrome.

Mol Ther 2010 Jun 23;18(6):1094-102. Epub 2010 Mar 23.

Department of Pediatrics, Saint Louis University, St Louis, Missouri 63104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mt.2010.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889747PMC
June 2010

Validation of keratan sulfate level in mucopolysaccharidosis type IVA by liquid chromatography-tandem mass spectrometry.

J Inherit Metab Dis 2010 Dec 27;33 Suppl 3:S35-42. Epub 2010 Jan 27.

Department of Pediatrics, Saint Louis University Doisy Research Center, 1100 South Grand Blvd, St Louis, MO 63104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10545-009-9013-xDOI Listing
December 2010

Sacral dimple: incidental findings from newborn evaluation. Mucopolysaccharidosis IVA disease.

Acta Paediatr 2009 May;98(5):768-9, 910-2

Department of Pediatrics, Saint Louis University, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1651-2227.2009.01134.xDOI Listing
May 2009

Enzyme replacement therapy in a murine model of Morquio A syndrome.

Hum Mol Genet 2008 Mar 3;17(6):815-24. Epub 2007 Dec 3.

Department of Pediatrics, St Louis University, Doisy Research Center, 1100 South Grand Blvd., Room 307, St Louis, MO 63104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddm353DOI Listing
March 2008

Analytical method for determination of disaccharides derived from keratan sulfates in human serum and plasma by high-performance liquid chromatography/turbo-ionspray ionization tandem mass spectrometry.

Biomed Chromatogr 2007 Apr;21(4):356-62

Drug Metabolism and Physicochemistry Research Laboratory, Daiichi Pharmaceutical Co. Ltd, 1-16-13 Kita-Kasai, Edogawa-ku, Tokyo 134-8630, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bmc.760DOI Listing
April 2007

Validation study of a method for assaying DE-310, a macromolecular carrier conjugate containing an anti-tumor camptothecin derivative, and the free drug in human plasma by HPLC and LC/MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Apr;818(2):249-56

Drug Metabolism and Physicochemical Property Research Laboratory, Daiichi Pharmaceutical Co. Ltd., 1-16-13 Kitakasai, Edogawa-ku, Tokyo 134-8630, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchromb.2005.01.005DOI Listing
April 2005

Validation study of assay method for DE-310, a novel polymer-bound camptothecin derivative, and the free drug in mouse plasma by liquid chromatography with fluorimetric detection.

J Chromatogr B Analyt Technol Biomed Life Sci 2004 Mar;801(2):157-64

Drug Metabolism and Physicochemical Property Research Laboratory, Daiichi Pharmaceutical Co. Ltd., 1-16-13 Kitakasai, Edogawa-ku, 134-8630 Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchromb.2003.10.067DOI Listing
March 2004