Torsten Witte

Torsten Witte

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Torsten Witte

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[JAK Inhibitors in Rheumatology].

Authors:
Torsten Witte

Dtsch Med Wochenschr 2019 Jun 4;144(11):748-752. Epub 2019 Jun 4.

Klinik für Immunologie und Rheumatologie der Medizinischen Hochschule Hannover.

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http://dx.doi.org/10.1055/a-0652-2731DOI Listing
June 2019

[Actual Treatment Options for Giant Cell Arteritis].

Dtsch Med Wochenschr 2019 May 26;144(9):595-600. Epub 2019 Apr 26.

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http://dx.doi.org/10.1055/a-0832-3563DOI Listing
May 2019

CD74 is a T cell antigen in spondyloarthritis.

Clin Exp Rheumatol 2019 May 22. Epub 2019 May 22.

Division of Immunology and Rheumatology, Hannover Medical University, Hannover, Germany.

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May 2019

[Sjögren's syndrome].

Authors:
Torsten Witte

Z Rheumatol 2019 Apr 1. Epub 2019 Apr 1.

Klinik für Immunologie und Rheumatologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

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http://dx.doi.org/10.1007/s00393-019-0625-8DOI Listing
April 2019

[What is certain in the treatment of rheumatoid arthritis?]

Authors:
Torsten Witte

Internist (Berl) 2018 Dec;59(12):1249-1254

Klinik für Immunologie und Rheumatologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

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http://dx.doi.org/10.1007/s00108-018-0510-6DOI Listing
December 2018

[Sjögren's Syndrome: Early diagnosis and effective treatment].

Authors:
Torsten Witte

Dtsch Med Wochenschr 2018 12 3;143(24):1778-1782. Epub 2018 Dec 3.

Klinik für Immunologie und Rheumatologie der Medizinischen Hochschule Hannover.

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http://dx.doi.org/10.1055/a-0547-1025DOI Listing
December 2018

Tuberculous coxitis with trochanteric bursitis manifesting a year after immigration to Germany: a case report.

J Med Case Rep 2018 Nov 7;12(1):332. Epub 2018 Nov 7.

Hannover Medical University, Clinic for Immunology and Rheumatology, Carl-Neubergstr. 1, 30625, Hannover, Germany.

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1867-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220512PMC
November 2018

Anti-CD74 antibodies have no diagnostic value in early axial spondyloarthritis: data from the spondyloarthritis caught early (SPACE) cohort.

Arthritis Res Ther 2018 03 1;20(1):38. Epub 2018 Mar 1.

Department of Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13075-018-1535-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831708PMC
March 2018

Histamine H2 receptor stimulation upregulates T2 chemokine CCL17 production in human M2a macrophages.

J Allergy Clin Immunol 2018 Feb 18;141(2):782-785.e5. Epub 2017 Jul 18.

Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.jaci.2017.06.023DOI Listing
February 2018

Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].

Clin Immunol 2018 02 7;187:137-138. Epub 2017 Dec 7.

Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.11.012DOI Listing
February 2018

Comment on: Rituximab therapy for Takayasu arteritis: a seven patients experience and a review of the literature.

Rheumatology (Oxford) 2018 Jan 29. Epub 2018 Jan 29.

Vasculitis and Lupus Clinic, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, UK.

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http://dx.doi.org/10.1093/rheumatology/kex493DOI Listing
January 2018

Autoantibodies binding to stathmin-4: new marker for polyneuropathy in primary Sjögren's syndrome.

Immunol Res 2017 12;65(6):1099-1102

Private Practice, Rheumatology, Schönsteinstr. 63, Cologne, Germany.

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http://dx.doi.org/10.1007/s12026-017-8970-7DOI Listing
December 2017

Autoimmunity and primary immunodeficiency: two sides of the same coin?

Nat Rev Rheumatol 2017 Dec;14(1):7-18

Klinik für Immunologie und Rheumatologie, Medizinische Hochschule Hannover (MHH), Carl-Neuberg Straße 1, D-30625 Hannover, Germany.

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http://dx.doi.org/10.1038/nrrheum.2017.198DOI Listing
December 2017

Comment on: New onset of lupus nephritis in two patients with SLE shortly after initiation of treatment with belimumab.

Authors:
Torsten Witte

Semin Arthritis Rheum 2017 10 19;47(2):e11. Epub 2017 Jul 19.

Klinik für Immunologie und Rheumatologie Medizinische Hochschule Hannover Carl-Neuberg-St 1, 30625 Hannover Germany. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.07.008DOI Listing
October 2017

Cerebrospinal Fluid Findings in Neurological Diseases Associated with Sjögren's Syndrome.

Eur Neurol 2017 21;77(1-2):91-102. Epub 2016 Dec 21.

Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1159/000454765DOI Listing
September 2017

Limited role of interferon-kappa (IFNK) truncating mutations in common variable immunodeficiency.

Cytokine 2017 08 19;96:71-74. Epub 2017 Mar 19.

Department for Clinical Immunology and Rheumatology, Hannover Medical School, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S10434666173007
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http://dx.doi.org/10.1016/j.cyto.2017.03.005DOI Listing
August 2017

Evaluation of RAG1 mutations in an adult with combined immunodeficiency and progressive multifocal leukoencephalopathy.

Clin Immunol 2017 06 20;179:1-7. Epub 2017 Feb 20.

Department for Clinical Immunology and Rheumatology, Hannover Medical School, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.12.013DOI Listing
June 2017

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.

PLoS Genet 2017 Jun 22;13(6):e1006820. Epub 2017 Jun 22.

Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501660PMC
June 2017

Limitation of Simultaneous Analysis of T-Cell Receptor and κ-Deleting Recombination Excision Circles Based on Multiplex Real-Time Polymerase Chain Reaction in Common Variable Immunodeficiency Patients.

Int Arch Allergy Immunol 2016 1;171(2):136-140. Epub 2016 Dec 1.

Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany.

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https://www.karger.com/Article/FullText/450950
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http://dx.doi.org/10.1159/000450950DOI Listing
February 2017

LILRA3 deficiency is not involved in the giant cell arteritis and systemic sclerosis predisposition.

Clin Exp Rheumatol 2016 Sep-Oct;34 Suppl 100(5):208-209. Epub 2016 Jul 22.

Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, PTS-Granada, Spain.

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January 2017

LILRA3 deletion is a genetic risk factor of HIV infection.

AIDS 2017 01;31(1):25-34

aClinic for Immunology and Rheumatology, Hannover Medical School (MHH), Hannover bDepartment of Infectious Diseases cDepartment of Infectious Diseases Epidemiology, Robert Koch-Institute, Berlin dAESKU Diagnostics, Wendelsheim eGerman Center for Infection Research (DZIF), Partner-site Hannover-Braunschweig, Hannover, Germany.

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http://dx.doi.org/10.1097/QAD.0000000000001304DOI Listing
January 2017

Two Subsets of Large Vessel Vasculitis Characterized by the Absence or Presence of Spondyloarthritis or its Associated Diseases.

Open Rheumatol J 2016 30;10:101-108. Epub 2016 Nov 30.

Department of Rheumatology & Immunology, Hannover Medical University, Hannover, Germany.

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http://dx.doi.org/10.2174/1874312901610010101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204068PMC
November 2016

CD4(+) T cells in patients with chronic inflammatory rheumatic disorders show distinct levels of exhaustion.

J Allergy Clin Immunol 2016 08 2;138(2):586-589.e10. Epub 2016 Jun 2.

Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.04.013DOI Listing
August 2016

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.

Clin Immunol 2016 07 22;168:25-29. Epub 2016 Apr 22.

Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940221PMC
July 2016

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Arthritis Rheumatol 2016 05;68(5):1290-1300

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1002/art.39560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019501PMC
May 2016

[Sjögren's syndrome].

Dtsch Med Wochenschr 2016 Apr 14;141(8):544-50. Epub 2016 Apr 14.

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http://dx.doi.org/10.1055/s-0041-111436DOI Listing
April 2016

Anti-IFN-γ autoantibodies are strongly associated with HLA-DR*15:02/16:02 and HLA-DQ*05:01/05:02 across Southeast Asia.

J Allergy Clin Immunol 2016 Mar 29;137(3):945-8.e8. Epub 2015 Oct 29.

Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.1016/j.jaci.2015.09.018DOI Listing
March 2016

Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells.

Sci Rep 2015 Dec 16;5:18308. Epub 2015 Dec 16.

Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School (MHH), Feodor-Lynen-Straße 7, D30625 Hannover.

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http://dx.doi.org/10.1038/srep18308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680940PMC
December 2015

IgG4-related sialadenitis: IgG4 is helpful, but biopsies are still crucial.

Arthritis Res Ther 2015 Dec 18;17:368. Epub 2015 Dec 18.

Sektion Rheumatologie und Klinische Immunologie, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Pettenkoferstraße 8a, 80336, München, Germany.

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http://dx.doi.org/10.1186/s13075-015-0888-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704542PMC
December 2015

Methotrexate as combination partner of TNF inhibitors and tocilizumab. What is reasonable from an immunological viewpoint?

Authors:
Torsten Witte

Clin Rheumatol 2015 Apr 22;34(4):629-34. Epub 2015 Jan 22.

Clinic for Immunology and Rheumatology, Medical University of Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Germany,

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http://dx.doi.org/10.1007/s10067-015-2861-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365184PMC
April 2015

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.

Am J Hum Genet 2015 Apr 26;96(4):565-80. Epub 2015 Mar 26.

Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain.

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http://dx.doi.org/10.1016/j.ajhg.2015.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385191PMC
April 2015

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Hum Mol Genet 2015 Jan 8;24(2):582-96. Epub 2014 Sep 8.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology and US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/hmg/ddu455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275071PMC
January 2015

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.

Am J Hum Genet 2014 Jan;94(1):47-61

Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, Granada 18016, Spain.

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http://eprints.gla.ac.uk/104672/1/104672.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971300571
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http://dx.doi.org/10.1016/j.ajhg.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882906PMC
January 2014

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

Nat Genet 2013 Nov 6;45(11):1284-92. Epub 2013 Oct 6.

1] Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA. [2] Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

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http://dx.doi.org/10.1038/ng.2792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867192PMC
November 2013

Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene.

PLoS One 2013 2;8(4):e60646. Epub 2013 Apr 2.

Cellular Biology and Immunology Department, Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (IPBLN- Consejo Superior de Investigaciones Científicas), Granada, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060646PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614928PMC
September 2013

Bamboo nodes associated with mixed connective tissue disease as a cause of hoarseness.

Rheumatol Int 2013 Mar 16;33(3):777-81. Epub 2011 Nov 16.

Department of Pedaudiology and Phoniatrics, Medical University Hannover, Hannover, Germany.

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http://dx.doi.org/10.1007/s00296-011-2214-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576552PMC
March 2013

Unilateral hypertrophic osteoarthropathy in a patient with a vascular graft infection.

J Clin Rheumatol 2012 Sep;18(6):307-9

Clinic for Immunology and Rheumatology, Hannover Medical School, Hannover, Germany.

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September 2012

NKG2C deletion is a risk factor of HIV infection.

AIDS Res Hum Retroviruses 2012 Aug 3;28(8):844-51. Epub 2012 May 3.

Department of Clinical Immunology and Rheumatology, Hannover Medical University, Hannover, Germany.

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http://dx.doi.org/10.1089/AID.2011.0253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399562PMC
August 2012

Treatment of refractory giant cell arteritis with cyclophosphamide:a retrospective analysis of 35 patients from three centres.

Clin Exp Rheumatol 2012 Jan-Feb;30(1 Suppl 70):S70-6. Epub 2012 May 14.

University of Lübeck, Department of Rheumatology, Vasculitis Center & Klinikum Bad Bramstedt, Germany.

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August 2012

Basophils from humans with systemic lupus erythematosus do not express MHC-II.

Nat Med 2012 Apr 5;18(4):488-9; author reply 489-90. Epub 2012 Apr 5.

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http://dx.doi.org/10.1038/nm.2663DOI Listing
April 2012

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.

PLoS Genet 2011 Jul 14;7(7):e1002178. Epub 2011 Jul 14.

Department of Epidemiology, M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1371/journal.pgen.1002178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136437PMC
July 2011

Aspects of innate immunity in Sjögren's syndrome.

Arthritis Res Ther 2011 May 27;13(3):218. Epub 2011 May 27.

Clinic for Immunology and Rheumatology, Medical School Hannover, Carl-Neuberg-Str, 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1186/ar3318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218872PMC
May 2011

Immunology: Prevention of infections in patients with autoimmune diseases.

Nat Rev Rheumatol 2011 Apr 8;7(4):198-200. Epub 2011 Feb 8.

Department of Clinical Immunology and Rheumatology, Medical University Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1038/nrrheum.2011.14DOI Listing
April 2011