Torsten Luksch

Torsten Luksch

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Torsten Luksch

Torsten Luksch

Publications by authors named "Torsten Luksch"

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16Publications

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Editorial.

Chimia (Aarau) 2019 Dec;73(12):969

ETH Zurich.

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December 2019

Screening a protein kinase inhibitor library against Plasmodium falciparum.

Malar J 2017 11 7;16(1):446. Epub 2017 Nov 7.

Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.

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http://dx.doi.org/10.1186/s12936-017-2085-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678585PMC
November 2017

The design and synthesis of potent and selective inhibitors of Trypanosoma brucei glycogen synthase kinase 3 for the treatment of human african trypanosomiasis.

J Med Chem 2014 Sep 8;57(18):7536-49. Epub 2014 Sep 8.

Drug Discovery Unit, College of Life Sciences, University of Dundee , Sir James Black Centre, Dow Street, Dundee DD1 5EH, U.K.

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http://dx.doi.org/10.1021/jm500239bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175002PMC
September 2014

Current challenges and trends in the discovery of agrochemicals.

Science 2013 Aug;341(6147):742-6

Syngenta Crop Protection AG, Research Chemistry, Stein, Switzerland.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1237227
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http://dx.doi.org/10.1126/science.1237227DOI Listing
August 2013

From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules.

ChemMedChem 2013 Jul 14;8(7):1127-37. Epub 2013 Jun 14.

Drug Discovery Unit (DDU), Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Sir James Black Centre, DD1 5EH, UK.

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http://dx.doi.org/10.1002/cmdc.201300072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728731PMC
July 2013

Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3.

ChemMedChem 2011 Dec 13;6(12):2214-24. Epub 2011 Sep 13.

Drug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee, DD1 5EH, UK.

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http://dx.doi.org/10.1002/cmdc.201100344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272345PMC
December 2011

Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry.

Nat Chem 2010 Jun 16;2(6):490-7. Epub 2010 May 16.

EastChem, School of Chemistry, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh EH9 3JJ, UK.

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http://dx.doi.org/10.1038/nchem.658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913121PMC
June 2010

Pyrrolidine derivatives as plasmepsin inhibitors: binding mode analysis assisted by molecular dynamics simulations of a highly flexible protein.

ChemMedChem 2010 Mar;5(3):443-54

Philipps-Universität Marburg, Institut für Pharmazeutische Chemie, Marbacher Weg 6, 35032 Marburg, Germany.

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http://doi.wiley.com/10.1002/cmdc.200900452
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http://dx.doi.org/10.1002/cmdc.200900452DOI Listing
March 2010

Computer-aided design and synthesis of nonpeptidic plasmepsin II and IV inhibitors.

ChemMedChem 2008 Sep;3(9):1323-36

Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Marbacher Weg 6, 35032 Marburg, Germany.

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http://doi.wiley.com/10.1002/cmdc.200700270
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http://dx.doi.org/10.1002/cmdc.200700270DOI Listing
September 2008

Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors.

Bioorg Med Chem 2008 Sep 7;16(18):8574-86. Epub 2008 Aug 7.

Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Marbacher Weg 6, 35032 Marburg, Germany.

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http://dx.doi.org/10.1016/j.bmc.2008.08.012DOI Listing
September 2008