Publications by authors named "Torsten Haferlach"

100Publications

A 19-year-old patient with atypical chronic myeloid leukemia.

Ann Hematol 2020 May 19;99(5):1145-1148. Epub 2020 Mar 19.

Abteilung Hämatologie und Internistische Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Am Klinikum 1, 07740, Jena, Germany.

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http://dx.doi.org/10.1007/s00277-020-03992-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196939PMC
May 2020

Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics.

iScience 2020 Jan 18;23(1):100780. Epub 2019 Dec 18.

LIMES-Institute, Department for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, Venusberg-Campus 1, Building 99, 53127 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.100780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992905PMC
January 2020

The power and potential of integrated diagnostics in acute myeloid leukaemia.

Br J Haematol 2020 01 6;188(1):36-48. Epub 2019 Dec 6.

MLL Munich Leukemia Laboratory, Munich, Germany.

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http://dx.doi.org/10.1111/bjh.16360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973013PMC
January 2020

Distinct and convergent consequences of splice factor mutations in myelodysplastic syndromes.

Am J Hematol 2020 02 18;95(2):133-143. Epub 2019 Nov 18.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1002/ajh.25673DOI Listing
February 2020

A decade with whole exome sequencing in haematology.

Br J Haematol 2020 02 10;188(3):367-382. Epub 2019 Oct 10.

Hematology Pathology Research Laboratory, Research Unit for Hematology and Research Unit for Pathology, Odense University Hospital, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1111/bjh.16249DOI Listing
February 2020

Differences in treatment and monitoring of chronic myeloid leukemia with regard to age, but not sex: Results from a population-based study.

Eur J Haematol 2019 Oct 28;103(4):362-369. Epub 2019 Aug 28.

Institute for Medical Information Sciences, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.

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http://dx.doi.org/10.1111/ejh.13293DOI Listing
October 2019

Myeloid malignancies with isolated 7q deletion can be further characterized by their accompanying molecular mutations.

Genes Chromosomes Cancer 2019 10 1;58(10):698-704. Epub 2019 May 1.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, Munich, 81377, Germany.

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http://dx.doi.org/10.1002/gcc.22761DOI Listing
October 2019

Impact of 9q deletions on the classification of patients with acute myeloid leukemia.

J Cancer Res Clin Oncol 2019 Nov 29;145(11):2871-2874. Epub 2019 Mar 29.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00432-019-02908-0DOI Listing
November 2019

Impact of assay procedures on detection of MR status in chronic myeloid leukemia: Optimization of cDNA synthesis.

Int J Lab Hematol 2019 10 12;41(5):e109-e112. Epub 2019 Mar 12.

MLL Munich Leukemia Laboratory, Munich, Germany.

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http://dx.doi.org/10.1111/ijlh.13004DOI Listing
October 2019

More than a fusion gene: the - AML.

Blood 2019 03;133(10):1006-1007

MLL Munich Leukemia Laboratory.

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http://dx.doi.org/10.1182/blood-2019-01-896076DOI Listing
March 2019

Comprehensive molecular characterization of myeloid malignancies with 9q deletion.

Leuk Lymphoma 2019 10 7;60(10):2591-2593. Epub 2019 Mar 7.

MLL Munich Leukemia Laboratory , Munich , Germany.

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https://www.tandfonline.com/doi/full/10.1080/10428194.2019.1
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http://dx.doi.org/10.1080/10428194.2019.1585840DOI Listing
October 2019

Evidence of clonality in cases of hypereosinophilia of undetermined significance.

Leuk Lymphoma 2019 08 18;60(8):2071-2074. Epub 2019 Jan 18.

a MLL Munich Leukemia Laboratory , Munich , Germany.

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http://dx.doi.org/10.1080/10428194.2018.1564825DOI Listing
August 2019

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing.

Haematologica 2019 02 6;104(2):277-287. Epub 2018 Sep 6.

Department of Hematology, Oncology and Immunology, Philipps-University Marburg, and University Hospital Gießen and Marburg, Marburg, Germany

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.194258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355503PMC
February 2019

The Molecular Pathology of Myelodysplastic Syndrome.

Pathobiology 2019 23;86(1):24-29. Epub 2018 May 23.

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http://dx.doi.org/10.1159/000488712DOI Listing
January 2019

Molecular patterns in cytopenia patients with or without evidence of myeloid neoplasm-a comparison of 756 cases.

Leukemia 2018 10 30;32(10):2295-2298. Epub 2018 Mar 30.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, 81377, Munich, Germany.

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http://dx.doi.org/10.1038/s41375-018-0119-8DOI Listing
October 2018

Detection of recurrent and of novel fusion transcripts in myeloid malignancies by targeted RNA sequencing.

Leukemia 2018 05 26;32(5):1229-1238. Epub 2018 Feb 26.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, 81377, Munich, Germany.

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http://dx.doi.org/10.1038/s41375-017-0002-zDOI Listing
May 2018

The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.

Biochim Biophys Acta Mol Cell Res 2018 Jan 20;1865(1):105-116. Epub 2017 Sep 20.

Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK.

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http://dx.doi.org/10.1016/j.bbamcr.2017.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701546PMC
January 2018

Cord-Blood Transplantation in Patients with Minimal Residual Disease.

N Engl J Med 2016 12;375(22):2204

Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1056/NEJMc1612872DOI Listing
December 2016

MYC rearranged B-cell neoplasms: Impact of genetics on classification.

Cancer Genet 2016 Oct 14;209(10):431-439. Epub 2016 Sep 14.

MLL Munich Leukemia Laboratory, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2016.08.007DOI Listing
October 2016

Disease-modifying activity of ruxolitinib in a patient with JAK2-negative CMML-2.

Leuk Lymphoma 2017 05 23;58(5):1271-1272. Epub 2016 Sep 23.

a Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl-Gustav-Carus, Technische Universität , Dresden , Germany.

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http://dx.doi.org/10.1080/10428194.2016.1225209DOI Listing
May 2017

The 5q deletion size in myeloid malignancies is correlated to additional chromosomal aberrations and to TP53 mutations.

Genes Chromosomes Cancer 2016 10 4;55(10):777-85. Epub 2016 Jul 4.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, Munich, 81377, Germany.

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http://dx.doi.org/10.1002/gcc.22377DOI Listing
October 2016

BCR-ABL1-positive and JAK2 V617F-positive clones in 23 patients with both aberrations reveal biologic and clinical importance.

Br J Haematol 2017 01 5;176(1):135-139. Epub 2016 Feb 5.

Munich Leukaemia Laboratory GmbH, Munich, Germany.

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http://dx.doi.org/10.1111/bjh.13932DOI Listing
January 2017

Why germline variations in ALL can matter.

Lancet Oncol 2015 Dec 28;16(16):1577-8. Epub 2015 Oct 28.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, 81377 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00440-4DOI Listing
December 2015

Integration of innate into adaptive immune responses in ZAP-70-positive chronic lymphocytic leukemia.

Blood 2016 Jan 27;127(4):436-48. Epub 2015 Oct 27.

3rd Department of Medicine, Technical University Munich, Munich, Germany; Department of Haematology, University of Cambridge, Cambridge, United Kingdom;

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http://dx.doi.org/10.1182/blood-2015-05-646935DOI Listing
January 2016

Genetic characterization of T-PLL reveals two major biologic subgroups and JAK3 mutations as prognostic marker.

Genes Chromosomes Cancer 2016 Jan 23;55(1):82-94. Epub 2015 Oct 23.

MLL Munich Leukemia Laboratory, Max-Lebsche-Platz 31, Munich, 81377, Germany.

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http://dx.doi.org/10.1002/gcc.22313DOI Listing
January 2016