Publications

Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn's disease is a risk factor for disease relapse in Japanese patients.
J Gastroenterol 2017 Dec 22;52(12):1230-1239. Epub 2017 Feb 22.
Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba, Sendai, 980-8574, Japan.




The slow progressive nature of duodenal neuroendocrine tumor: a case report of long-term observation over 14 years.
Clin J Gastroenterol 2017 Oct 29;10(5):469-473. Epub 2017 Jun 29.
Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.






Nationwide epidemiological survey of early chronic pancreatitis in Japan.
J Gastroenterol 2017 Aug 27;52(8):992-1000. Epub 2017 Jan 27.
Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.

Factors Associated With Metachronous Gastric Cancer Development After Endoscopic Submucosal Dissection for Early Gastric Cancer.
J Clin Gastroenterol 2017 Jul;51(6):494-499
*Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai †Department of Gastroenterology, Akita University Graduate School of Medicine, Akita, Japan.




Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.
Gastroenterology 2017 May 11;152(6):1521-1535.e8. Epub 2017 Jan 11.
Department of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan; Japan Agency for Medical Research and Development, Core Research for Evolutional Science and Technology (CREST), Tokyo, Japan.


Clinical Practice Guidelines for Pancreatic Cancer 2016 From the Japan Pancreas Society: A Synopsis.
Pancreas 2017 May/Jun;46(5):595-604
From the *Clinic of Fukuoka Government Building, Hamanomachi Hospital, Fukuoka; †Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital; ‡Department of Gastroenterology, Tokyo Women's Medical University; §Department of Medical Oncology, Faculty of Medicine, Kyorin University; ∥Department of Radiation Oncology, National Cancer Center Hospital, Tokyo; ¶Department of Gastroenterology, JA Onomichi General Hospital, Onomichi; #Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai; and **Department of Gastroenterology and Hepatology, Kansai Medical University, Hirakata, Japan.


Evidence-based clinical practice guidelines for cholelithiasis 2016.
J Gastroenterol 2017 Mar 10;52(3):276-300. Epub 2016 Dec 10.
, Guidelines Committee for the Japanese Society of Gastroenterology ''Evidence-based clinical practice guidelines for cholelithiasis'', Hiroshima, Japan.




Clinicopathological Characteristics of Young Patients With Pancreatic Cancer: An Analysis of Data From Pancreatic Cancer Registry of Japan Pancreas Society.
Pancreas 2016 Nov;45(10):1411-1417
From the *Japan Pancreas Society, Sendai; †Department of Surgery, Graduate School of Medicine, Osaka University, Osaka; ‡Second Department of Surgery, Wakayama Medical University, Wakayama; §Department of Surgery and ∥Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai; ¶Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka; #Department of Surgery, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki; **Department of Surgery, Kansai Medical University, Osaka; ††Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya; ‡‡Department of Surgery, Shiga University of Medical Science, Otsu; §§Department of Gastroenterology, IMS Sapporo Digestive Center General Hospital, Sapporo; ∥∥Department of Endoscopy, Nagoya University Hospital; and ¶¶Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya; ##Kyushu University Hospital Cancer Center, Fukuoka; ***Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo; †††Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto; and ‡‡‡Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.



Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015.
J Gastroenterol 2016 Aug 21;51(8):751-67. Epub 2016 Jun 21.
Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, Japan.


Evidence-based clinical practice guidelines for liver cirrhosis 2015.
J Gastroenterol 2016 Jul 31;51(7):629-50. Epub 2016 May 31.
Guidelines Committee for creating and evaluating the ''Evidence-based clinical practice guidelines for liver cirrhosis'', Japanese Society of Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, Japan.

MicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6.
World J Gastrointest Oncol 2016 Jul;8(7):532-42
Toshihiro Tadano, Yoichi Kakuta, Shin Hamada, Yosuke Shimodaira, Masatake Kuroha, Yoko Kawakami, Tomoya Kimura, Hisashi Shiga, Katsuya Endo, Atsushi Masamune, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

No Association Between CEL-HYB Hybrid Allele and Chronic Pancreatitis in Asian Populations.
Gastroenterology 2016 Jun 3;150(7):1558-1560.e5. Epub 2016 Mar 3.
Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai, China; Shanghai Institute of Pancreatic Diseases, Shanghai, China. Electronic address:


Reactivation of resolved hepatitis B virus infection with immune escape mutations after long-term corticosteroid therapy.
Clin J Gastroenterol 2016 Apr 26;9(2):93-8. Epub 2016 Feb 26.
Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba-ku, Sendai, 980-8574, Japan.

A case of a ruptured submucosal aneurysm of the small intestine identified using double-balloon enteroscopy.
Clin J Gastroenterol 2016 Apr 18;9(2):49-54. Epub 2016 Mar 18.
Division of Gastroenterology, Department of Internal Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba-ku, Sendai, 980-8574, Japan.


Evidence-based clinical practice guidelines for peptic ulcer disease 2015.
J Gastroenterol 2016 Mar 15;51(3):177-94. Epub 2016 Feb 15.
Guidelines Committee for creating and evaluating the "Evidence-based clinical practice guidelines for peptic ulcer", the Japanese Society of Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, Japan.

Evidence-based clinical practice guidelines for chronic pancreatitis 2015.
J Gastroenterol 2016 Feb 4;51(2):85-92. Epub 2016 Jan 4.
Guidelines Committee for creating and evaluating the "Evidence-based clinical practice guidelines for chronic pancreatitis", The Japanese Society of Gastroenterology (JSGE), K-18 Building 8F, 8-9-13. Ginza, Chuo, Tokyo, 104-0061, Japan.

Characteristics of symptomatic reflux episodes in Japanese proton pump inhibitor-refractory non-erosive reflux disease patients.
World J Gastroenterol 2015 Dec;21(47):13352-9
Kenichiro Nakagawa, Tomoyuki Koike, Katsunori Iijima, Masahiro Saito, Hiroki Kikuchi, Waku Hatta, Nobuyuki Ara, Kaname Uno, Naoki Asano, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai Miyagi 980-8574, Japan.

Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium.
Pancreas 2015 Nov;44(8):1195-210
From the *Division of Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, CA; †Division of Gastroenterology, Tohoku University Hospital, Sendai, Japan; ‡National Institute for Health Research Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom; §Division of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA; ||Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN; ¶Section of Digestive Diseases, Department of Internal Medicine, Yale University, New Haven, CT; #Department of Surgery, University of Auckland, New Zealand; **Division of Gastroenterology, University of Minnesota, Minneapolis, MN; ††Department of Medicine, University Medicine Greifswald, Greifswald, Germany; ‡‡Division of Gastroenterology, Kyoto University Hospital, Kyoto, Japan; and §§Division of Gastroenterology, University of Massachusetts, Worcester, MA.

Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis.
Am J Physiol Gastrointest Liver Physiol 2015 Oct 27;309(8):G688-94. Epub 2015 Aug 27.
Pediatric Nutritional Medicine, Klinikum rechts der Isar; Else Kröner-Fresenius-Zentrum für Ernährungsmedizin & Zentralinstitut für Ernährungs-und Lebensmittelforschung, Technische Universität München, Munich, Germany; and.

Clinicopathological Features of Type 2 Autoimmune Pancreatitis in Japan: Results of a Multicenter Survey.
Pancreas 2015 Oct;44(7):1072-7
From the *Department of Anatomic Pathology, Kurashiki Central Hospital, Kurashiki; †Nishimori Clinic, Sakawa, Kochi; ‡Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya; §Department of Gastroenterology and Hepatology, Kansai Medical University, Hirakata, Osaka; ∥Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka; ¶Center for Health, Safety, and Environmental Management, Shinshu University, Matsumoto; #Division of Hepato-Biliary-Pancreatic Surgery, Tohoku University Graduate School of Medicine, Sendai; **Department of Gastroenterology, Kitakyushu General Hospital, Kitakyushu; and †† Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Japanese Clinical Guidelines for Endoscopic Treatment of Pancreatolithiasis.
Pancreas 2015 Oct;44(7):1053-64
From the *Department of Gastroenterology, Second Teaching Hospital, Fujita Health University, Nagoya, †Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, Tokyo, ‡Department of Internal Medicine, Aizu Medical Center, Fukushima Medical University, Fukushima, §Department of Community-based Medical Education, Nagoya City University Graduate School of Medical Sciences, Nagoya, ∥Department of General Medicine, Hiroshima University Graduate School of Medical Science, Programs of Applied Medicine, Clinical Pharmacotherapy, Hiroshima, ¶Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, #Department of Gastroenterology, Sendai City Medical Center, Sendai, *Division of Biliopancreatology, Sapporo Kosei General Hospital, Sapporo, ††Department of Surgery, Jichi Medical University, Shimotsuke, ‡‡Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, §§Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, ∥∥Department of Gastroenterology, Tokyo Women's Medical University, Tokyo, ¶¶Department of Surgery, Kyorin University School of Medicine, Mitaka, and ##Department of Surgery, Kinki University School of Medicine, Osakasayama, Japan.


IgG4-unrelated type 1 autoimmune pancreatitis.
World J Gastroenterol 2015 Sep;21(33):9808-16
Eriko Nakano, Atsushi Kanno, Atsushi Masamune, Naoki Yoshida, Seiji Hongo, Shin Miura, Tetsuya Takikawa, Shin Hamada, Kiyoshi Kume, Kazuhiro Kikuta, Morihisa Hirota, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

A Comparison of Short- and Long-Term Therapeutic Outcomes of Infliximab- versus Tacrolimus-Based Strategies for Steroid-Refractory Ulcerative Colitis.
Gastroenterol Res Pract 2016 20;2016:3162595. Epub 2016 Jan 20.
Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba-ku, Sendai 980-8574, Japan.

Plasma Kallikrein-Dependent Transforming Growth Factor-β Activation in Patients With Chronic Pancreatitis and Pancreatic Cancer.
Pancreas 2017 03;46(3):e20-e22
Micro-Signaling Regulation Technology Unit, RIKEN Center for Life Science Technologies, Wako, Japan; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Endoscopy, Nagoya University Hospital, Nagoya, Japan; Micro-Signaling Regulation Technology Unit, RIKEN Center for Life Science Technologies, Wako, Japan; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan; Micro-Signaling Regulation Technology Unit, RIKEN Center for Life Science Technologies, Wako, Japan

American Pancreatic Association and Japan Pancreas Society: Sisterhood Memorandum of Understanding.
Pancreas 2017 04;46(4):453-454
From the *UCLA Agi Hirshberg Center for Pancreatic Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA; †Japan Pancreas Society, Tohoku University Graduate School of Medicine, Sendai, Japan; ‡American Pancreatic Association, University of Miami, Miami, FL; §Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA; and ∥Pancreas Research Foundation of Japan, Tokyo, Japan.


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