Tony Yuen

Tony Yuen

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Tony Yuen

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FSH-metabolic circuitry and menopause.

J Mol Endocrinol 2019 Oct;63(3):R73-R80

The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1530/JME-19-0152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992500PMC
October 2019

Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages.

FASEB J 2019 Aug 7;33(8):9167-9181. Epub 2019 May 7.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1096/fj.201900010RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662975PMC
August 2019

Reply to Graham et al.: In silico atomistic coordinates and molecular dynamics simulation trajectories of the glucocerebrosidase-saposin C complex.

Proc Natl Acad Sci U S A 2019 Jun;116(23):11101-11102

Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, London WC1N 1AX, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1905744116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561302PMC
June 2019

FSH Beyond Fertility.

Front Endocrinol (Lausanne) 2019 19;10:136. Epub 2019 Mar 19.

The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.3389/fendo.2019.00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433784PMC
March 2019

FSIP1 regulates autophagy in breast cancer.

Proc Natl Acad Sci U S A 2018 12 3;115(51):13075-13080. Epub 2018 Dec 3.

Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

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http://dx.doi.org/10.1073/pnas.1809681115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304934PMC
December 2018

Emerging concepts in the epidemiology, pathophysiology, and clinical care of osteoporosis across the menopausal transition.

Matrix Biol 2018 10 5;71-72:70-81. Epub 2018 May 5.

The Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.05.001DOI Listing
October 2018

Regulation of Skeletal Homeostasis.

Endocr Rev 2018 10;39(5):701-718

Maine Medical Center Research Institute, Scarborough, Maine.

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http://dx.doi.org/10.1210/er.2018-00050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173473PMC
October 2018

FSH, Bone Mass, Body Fat, and Biological Aging.

Endocrinology 2018 10;159(10):3503-3514

The Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1210/en.2018-00601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134257PMC
October 2018

Actions of pituitary hormones beyond traditional targets.

J Endocrinol 2018 06 19;237(3):R83-R98. Epub 2018 Mar 19.

The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1530/JOE-17-0680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924585PMC
June 2018

Opening windows for bone remodeling through a SLIT.

J Clin Invest 2018 04 5;128(4):1255-1257. Epub 2018 Mar 5.

Mount Sinai Bone Program, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.

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http://dx.doi.org/10.1172/JCI120325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873855PMC
April 2018

FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.

Proc Natl Acad Sci U S A 2017 07 3;114(29):7683-7688. Epub 2017 Jul 3.

Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China;

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http://dx.doi.org/10.1073/pnas.1621486114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530656PMC
July 2017

New developments in prenatal diagnosis of congenital adrenal hyperplasia.

J Steroid Biochem Mol Biol 2017 01 1;165(Pt A):121-123. Epub 2016 Jul 1.

Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2016.06.016DOI Listing
January 2017

Pituitary-bone connection in skeletal regulation.

Horm Mol Biol Clin Investig 2016 Nov;28(2):85-94

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http://dx.doi.org/10.1515/hmbci-2016-0015DOI Listing
November 2016

A novel mutation in HSD11B2 causes apparent mineralocorticoid excess in an Omani kindred.

Ann N Y Acad Sci 2016 07 15;1376(1):65-71. Epub 2016 Aug 15.

Department of Pediatrics and Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1111/nyas.13162DOI Listing
July 2016

Anabolic actions of Notch on mature bone.

Proc Natl Acad Sci U S A 2016 Apr 28;113(15):E2152-61. Epub 2016 Mar 28.

The Mount Sinai Bone Program, Department of Medicine, Mount Sinai School of Medicine, NY 10029; Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, NY 10029;

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http://dx.doi.org/10.1073/pnas.1603399113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839423PMC
April 2016

A rare CYP21A2 mutation in a congenital adrenal hyperplasia kindred displaying genotype-phenotype nonconcordance.

Ann N Y Acad Sci 2016 Jan 20;1364:5-10. Epub 2015 Aug 20.

Division of Adrenal Steroid Disorders, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1111/nyas.12864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761329PMC
January 2016

Questioning the association between bisphosphonates and atypical femoral fractures.

Ann N Y Acad Sci 2015 Jan 7;1335:1-9. Epub 2014 Oct 7.

Oxford University Institute of Musculoskeletal Sciences, Oxford, United Kingdom.

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http://doi.wiley.com/10.1111/nyas.12551
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http://dx.doi.org/10.1111/nyas.12551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289441PMC
January 2015

Bisphosphonates inactivate human EGFRs to exert antitumor actions.

Proc Natl Acad Sci U S A 2014 Dec 1;111(50):17989-94. Epub 2014 Dec 1.

Departments of Medicine, Pediatrics, and Chemical and Structural Biology, and the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029;

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http://dx.doi.org/10.1073/pnas.1421410111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273397PMC
December 2014

Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor.

Proc Natl Acad Sci U S A 2014 Nov 5;111(46):16502-7. Epub 2014 Nov 5.

Mount Sinai Bone Program and Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029; Structural and Chemical Biology, Mount Sinai School of Medicine, New York, NY 10029

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http://www.pnas.org/lookup/doi/10.1073/pnas.1419349111
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http://dx.doi.org/10.1073/pnas.1419349111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246276PMC
November 2014

Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11 β -Hydroxylase Deficiency.

Int J Endocrinol 2014 2;2014:185974. Epub 2014 Jun 2.

Steroid Disorder Program, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.hindawi.com/journals/ije/2014/185974/
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http://dx.doi.org/10.1155/2014/185974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060432PMC
July 2014

Noninvasive prenatal diagnosis of congenital adrenal hyperplasia using cell-free fetal DNA in maternal plasma.

J Clin Endocrinol Metab 2014 Jun 28;99(6):E1022-30. Epub 2014 Feb 28.

Departments of Pediatrics and Medicine (M.I.N., T.Y., C.P., A.K., M.Y., S.-M.K., L.S., M.Z.), Mt Sinai School of Medicine, New York, New York 10029; Centre for Research into Circulating Fetal Nucleic Acids (Y.K.T., P.J., K.C.A.C., G.J.W.L., R.W.K.C., Y.M.D.L.), Li Ka Shing Institute of Health Sciences, Hong Kong; and Department of Chemical Pathology (Y.K.T., P.J., K.C.A.C., G.J.W.L., R.W.K.C., Y.M.D.L.), The Chinese University of Hong Kong, Hong Kong SAR, China.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-1118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037720PMC
June 2014

Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes.

Proc Natl Acad Sci U S A 2013 Jul 17;110(27):11115-20. Epub 2013 Jun 17.

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19147, USA.

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http://dx.doi.org/10.1073/pnas.1220919110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704019PMC
July 2013

Genetic confirmation for a central role for TNFα in the direct action of thyroid stimulating hormone on the skeleton.

Proc Natl Acad Sci U S A 2013 Jun 28;110(24):9891-6. Epub 2013 May 28.

The Mount Sinai Bone Program and Department of Medicine and Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.1308336110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683712PMC
June 2013

Genotype-phenotype correlation in 1,507 families with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency.

Proc Natl Acad Sci U S A 2013 Feb 28;110(7):2611-6. Epub 2013 Jan 28.

Departments of Pediatrics and Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.1300057110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574953PMC
February 2013

Structure-phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia.

Proc Natl Acad Sci U S A 2013 Feb 28;110(7):2605-10. Epub 2013 Jan 28.

Centre of Cancer Research and Cell Biology, Queen's University of Belfast, Belfast BT9 7BL, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1221133110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574933PMC
February 2013

Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling.

J Clin Invest 2012 Oct 17;122(10):3737-41. Epub 2012 Sep 17.

Thyroid Research Unit and The Mount Sinai Bone Program, Department of Medicine, Mount Sinai School of Medicine, and James J. Peters VA Medical Center, New York, New York 10029, USA.

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http://www.jci.org/articles/view/63948
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http://dx.doi.org/10.1172/JCI63948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461920PMC
October 2012

An update on prenatal diagnosis and treatment of congenital adrenal hyperplasia.

Semin Reprod Med 2012 Oct 8;30(5):396-9. Epub 2012 Oct 8.

Adrenal Steroid Disorders Group, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1055/s-0032-1324723DOI Listing
October 2012

Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis.

Proc Natl Acad Sci U S A 2012 Sep 20;109(36):14574-9. Epub 2012 Aug 20.

Mount Sinai Bone Program, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.1212806109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437842PMC
September 2012

Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice.

Biochem Biophys Res Commun 2012 Jun 12;422(4):573-7. Epub 2012 May 12.

The Mount Sinai Bone Program, Mount Sinai School of Medicine, NY, USA.

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http://dx.doi.org/10.1016/j.bbrc.2012.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377787PMC
June 2012

Gaucher disease gene GBA functions in immune regulation.

Proc Natl Acad Sci U S A 2012 Jun 4;109(25):10018-23. Epub 2012 Jun 4.

Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1073/pnas.1200941109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382552PMC
June 2012

Congenital lipoid adrenal hyperplasia (a rare form of adrenal insufficiency and ambiguous genitalia) caused by a novel mutation of the steroidogenic acute regulatory protein gene.

Eur J Pediatr 2012 May 15;171(5):787-93. Epub 2011 Nov 15.

Department of Pediatrics, Mount Sinai School of Medicine, Box 1198, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1007/s00431-011-1620-5DOI Listing
May 2012

Blocking FSH action attenuates osteoclastogenesis.

Biochem Biophys Res Commun 2012 May 27;422(1):54-8. Epub 2012 Apr 27.

School of Stomatology, Wuhan University, Wuhan, China.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X120078
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http://dx.doi.org/10.1016/j.bbrc.2012.04.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219240PMC
May 2012

Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes.

Mol Cell Endocrinol 2012 Mar 25;350(1):10-9. Epub 2011 Nov 25.

Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S03037207110068
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http://dx.doi.org/10.1016/j.mce.2011.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919063PMC
March 2012

Adrenergic stimulation decreases osteoblast oxytocin synthesis.

Ann N Y Acad Sci 2011 Nov;1237:53-7

Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy.

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http://doi.wiley.com/10.1111/j.1749-6632.2011.06235.x
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http://dx.doi.org/10.1111/j.1749-6632.2011.06235.xDOI Listing
November 2011

Indentation as a technique to assess the mechanical properties of fallback foods.

Am J Phys Anthropol 2009 Dec;140(4):643-52

Department of Anthropology, Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC 20052, USA.

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http://dx.doi.org/10.1002/ajpa.21026DOI Listing
December 2009

Microtranscriptome regulation by gonadotropin-releasing hormone.

Mol Cell Endocrinol 2009 Apr 20;302(1):12-7. Epub 2009 Jan 20.

Department of Neurology, Mount Sinai School of Medicine, New York, NY, United States.

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http://dx.doi.org/10.1016/j.mce.2008.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683625PMC
April 2009

Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone beta subunit transcription.

J Mol Endocrinol 2007 Feb;38(1-2):315-30

Department of Pharmacology and Therapeutics, McGill University, 3655 Promenade Sir William Osler, Montréal, Québec, Canada H3G 1Y6.

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https://jme.bioscientifica.com/view/journals/jme/38/2/038031
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http://dx.doi.org/10.1677/jme.1.02196DOI Listing
February 2007

Influenza virus evades innate and adaptive immunity via the NS1 protein.

J Virol 2006 Jul;80(13):6295-304

Department of Microbiology, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1128/JVI.02381-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488970PMC
July 2006

Method for multiplex cellular detection of mRNAs using quantum dot fluorescent in situ hybridization.

Nucleic Acids Res 2005 Oct 13;33(18):e161. Epub 2005 Oct 13.

Department of Neurology, Mount Sinai School of Medicine, One Gustave L. Levy Place, NY 10029, USA.

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http://dx.doi.org/10.1093/nar/gni162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258180PMC
October 2005

Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress.

J Biol Chem 2004 Jun 12;279(26):27494-501. Epub 2004 Apr 12.

Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1074/jbc.M312135200DOI Listing
June 2004

Focused microarray analysis.

Methods 2003 Dec;31(4):306-16

Department of Neurology, Mount Sinai School of Medicine, Box 1137, 1 Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/s1046-2023(03)00161-0DOI Listing
December 2003

Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption.

FASEB J 2003 Mar;17(3):369-75

Mount Sinai Bone Program and Department of Medicine and Geriatrics, Mount Sinai School of Medicine, and Division of Endocrinology and Geriatric Research Education and Clinical Center (GRECC), Veterans Affairs Medical Center, New York, New York 10029, USA.

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http://dx.doi.org/10.1096/fj.02-0205comDOI Listing
March 2003

Validated genomic approach to study differentially expressed genes in complex tissues.

Neurochem Res 2002 Oct;27(10):1027-33

Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1023/a:1020900720328DOI Listing
October 2002

Coupling of GnRH concentration and the GnRH receptor-activated gene program.

Mol Endocrinol 2002 Jun;16(6):1145-53

Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1210/mend.16.6.0853DOI Listing
June 2002

Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays.

Nucleic Acids Res 2002 May;30(10):e48

Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC115302PMC
http://dx.doi.org/10.1093/nar/30.10.e48DOI Listing
May 2002

Monitoring G-protein-coupled receptor signaling with DNA microarrays and real-time polymerase chain reaction.

Methods Enzymol 2002 ;345:556-69

Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)45047-1DOI Listing
April 2002