Tony P George

Tony P George

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Tony P George

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Cannabis and Cannabinoids in Mood and Anxiety Disorders: Impact on Illness Onset and Course, and Assessment of Therapeutic Potential.

Am J Addict 2019 Oct 2. Epub 2019 Oct 2.

Department of Psychiatry, Addictions Division, Centre for Addiction and Mental Health (CAMH), University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/ajad.12963DOI Listing
October 2019

The neurobiology of impulsivity and substance use disorders: implications for treatment.

Ann N Y Acad Sci 2019 Sep 5;1451(1):71-91. Epub 2018 Oct 5.

Addictions Division, Centre for Addiction and Mental Health (CAMH), University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/nyas.13977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450787PMC
September 2019

Transcranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: A consensus paper on the present state of the science and the road ahead.

Neurosci Biobehav Rev 2019 09 2;104:118-140. Epub 2019 Jul 2.

Medical University of South Carolina (MUSC), USA.

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http://dx.doi.org/10.1016/j.neubiorev.2019.06.007DOI Listing
September 2019

Effects of Tobacco Smoking Status on Verbal Learning and Memory in Patients With Schizophrenia and Non-Psychiatric Controls.

Am J Addict 2019 Jul 10. Epub 2019 Jul 10.

Institute of Medical Sciences (IMS), University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1111/ajad.12903DOI Listing
July 2019

Exposure to attachment figure cue reduces cigarette craving.

Exp Clin Psychopharmacol 2019 May 9. Epub 2019 May 9.

Department of Psychiatry, Mount Sinai Hospital.

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http://dx.doi.org/10.1037/pha0000284DOI Listing
May 2019

Pharmacotherapies for co-occurring substance use and bipolar disorders: A systematic review.

Bipolar Disord 2019 May 11. Epub 2019 May 11.

Addictions Division, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12794
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http://dx.doi.org/10.1111/bdi.12794DOI Listing
May 2019

Cannabis and mental illness: a review.

Eur Arch Psychiatry Clin Neurosci 2019 Feb 19;269(1):107-120. Epub 2018 Dec 19.

Addictions Division, Centre for Addiction and Mental Health (CAMH), University of Toronto, 100 Stokes Street, BGB 3288, Toronto, ON, M6J 1H4, USA.

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http://dx.doi.org/10.1007/s00406-018-0970-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397076PMC
February 2019

Therapeutic cannabis use in 2018: where do we stand?

Lancet Psychiatry 2019 02;6(2):88-89

Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Addictions Division, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S22150366183041
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http://dx.doi.org/10.1016/S2215-0366(18)30417-6DOI Listing
February 2019

FAAH inhibition for treatment of problematic cannabis use.

Authors:
Tony P George

Lancet Psychiatry 2019 01 6;6(1):3-4. Epub 2018 Dec 6.

Department of Psychiatry, University of Toronto and Centre for Addiction and Mental Health (CAMH), Toronto, ON M6J 1H4, Canada. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(18)30462-0DOI Listing
January 2019

Cannabis legalisation in Canada: a crucial trial balloon.

Lancet Psychiatry 2019 01;6(1):5-6

Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Addictions Division, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S2215-0366(18)30460-7DOI Listing
January 2019

Neurobiological Determinants of Tobacco Smoking in Schizophrenia.

Front Psychiatry 2018 6;9:672. Epub 2018 Dec 6.

Addictions Division, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fpsyt.2018.00672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291492PMC
December 2018

Predicting smoking abstinence with biological and self-report measures of adherence to varenicline: Impact on pharmacogenetic trial outcomes.

Drug Alcohol Depend 2018 09 26;190:72-81. Epub 2018 Jun 26.

Department of Pharmacology and Toxicology, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada; Addictions Division, Centre for Addiction and Mental Health and Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, 100 Stokes Street BGB 3288, Toronto, ON, M6J 1H4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2018.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085881PMC
September 2018

Cannabis and Mood Disorders.

Curr Addict Rep 2018 Sep 10;5(3):336-345. Epub 2018 May 10.

Addictions Division, Centre for Addictions and Mental Health (CAMH), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA USA.

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http://dx.doi.org/10.1007/s40429-018-0214-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329464PMC
September 2018

A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine.

Cancer Epidemiol Biomarkers Prev 2018 08 31;27(8):882-891. Epub 2018 May 31.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072604PMC
August 2018

Effects of varenicline on cognitive function in non-smokers with schizophrenia.

Schizophr Res 2018 07 11;197:562-563. Epub 2017 Mar 11.

Institute of Medical Sciences (IMS), University of Toronto, Toronto, Ontario, Canada; Addictions Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.schres.2017.03.023DOI Listing
July 2018

Cannabis Legalization and Psychiatric Disorders: Caveat "Hemp-tor".

Can J Psychiatry 2018 07 26;63(7):447-450. Epub 2018 Feb 26.

4 Department of Psychology, University of Guelph, Guelph, Ontario.

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http://dx.doi.org/10.1177/0706743718762387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099771PMC
July 2018

Effects of short-term, high-frequency repetitive transcranial magnetic stimulation to bilateral dorsolateral prefrontal cortex on smoking behavior and cognition in patients with schizophrenia and non-psychiatric controls.

Schizophr Res 2018 07 24;197:441-443. Epub 2018 Feb 24.

Addictions Division, Centre for Addiction and Mental Health (CAMH), Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Canada; Institute of Medical Sciences, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2018.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108952PMC
July 2018

Using Mismatch Negativity to Investigate the Pathophysiology of Substance Use Disorders and Comorbid Psychosis.

Clin EEG Neurosci 2018 Jul 4;49(4):226-237. Epub 2018 Mar 4.

1 Temerty Centre for Therapeutic Brain Intervention, Division of Mood and Anxiety, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/1550059418760077DOI Listing
July 2018

Outcomes of an integrated care pathway for concurrent major depressive and alcohol use disorders: a multisite prospective cohort study.

BMC Psychiatry 2018 06 13;18(1):189. Epub 2018 Jun 13.

Addictions Division, Centre for Addiction and Mental Health (CAMH), 33 Russell Street, Office T519, Toronto, ON, M5S 2S1, Canada.

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http://dx.doi.org/10.1186/s12888-018-1770-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001012PMC
June 2018

Effects of extended cannabis abstinence on clinical symptoms in cannabis dependent schizophrenia patients versus non-psychiatric controls.

Schizophr Res 2018 04 9;194:55-61. Epub 2017 Mar 9.

The Institute of Medical Sciences (IMS), University of Toronto, Toronto, Ontario, Canada; Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.schres.2017.03.010DOI Listing
April 2018

A method to achieve extended cannabis abstinence in cannabis dependent patients with schizophrenia and non-psychiatric controls.

Schizophr Res 2018 04 12;194:47-54. Epub 2017 May 12.

The Institute of Medical Sciences (IMS), University of Toronto, Toronto, Ontario, Canada; Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S09209964173026
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http://dx.doi.org/10.1016/j.schres.2017.05.006DOI Listing
April 2018

Changes in tobacco consumption in cannabis dependent patients with schizophrenia versus non-psychiatric controls during 28-days of cannabis abstinence.

Drug Alcohol Depend 2018 04 12;185:181-188. Epub 2018 Feb 12.

Addictions Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; The Institute of Medical Sciences (IMS), University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.drugalcdep.2017.12.017DOI Listing
April 2018

A review of brain stimulation methods to treat substance use disorders.

Am J Addict 2018 03 19;27(2):71-91. Epub 2018 Feb 19.

Addictions Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/ajad.12674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034717PMC
March 2018

Measures and predictors of varenicline adherence in the treatment of nicotine dependence.

Addict Behav 2017 12 12;75:122-129. Epub 2017 Jul 12.

Department of Psychiatry, Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addbeh.2017.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581992PMC
December 2017

Impaired theta-gamma coupling during working memory performance in schizophrenia.

Schizophr Res 2017 11 29;189:104-110. Epub 2017 Jan 29.

Temerty Centre for Therapeutic Brain Intervention, Mood and Anxiety Division, Canada; Department of Psychiatry, Division of Brain and Therapeutics, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.01.044DOI Listing
November 2017

Differential effects of cannabis dependence on cortical inhibition in patients with schizophrenia and non-psychiatric controls.

Brain Stimul 2017 Mar - Apr;10(2):275-282. Epub 2016 Nov 14.

Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), 250 College Street, Toronto M5T 1R8, ON, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, 250 College Street, Toronto M5T 1R8, ON, Canada; Temerty Centre for Therapeutic Brain Intervention, CAMH, 1001 Queen Street West, Toronto M6J 1H4 ON, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, 1 King's College Circle Room 2374, Toronto M5S 1A8, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1935861X163030
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http://dx.doi.org/10.1016/j.brs.2016.11.004DOI Listing
September 2017

Integrated care pathway for co-occurring major depressive and alcohol use disorders: Outcomes of the first two years.

Am J Addict 2017 Sep 1;26(6):602-609. Epub 2017 Jun 1.

Addictions Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/ajad.12572DOI Listing
September 2017

Management of mood and anxiety disorders in patients receiving opioid agonist therapy: Review and meta-analysis.

Am J Addict 2017 Sep 4;26(6):551-563. Epub 2017 Jul 4.

Addictions Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/ajad.12581DOI Listing
September 2017

Sleep Disturbance During Smoking Cessation: Withdrawal or Side Effect of Treatment?

J Smok Cessat 2017 Jun 12;12(2):63-70. Epub 2016 Apr 12.

Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA, 19104.

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http://dx.doi.org/10.1017/jsc.2016.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443250PMC
June 2017

Sativex Associated With Behavioral-Relapse Prevention Strategy as Treatment for Cannabis Dependence: A Case Series.

J Addict Med 2016 Jul-Aug;10(4):274-9

Translational Addiction Research Laboratory, Campbell Family Mental Health, Research Institute (JMT, AS, GS, BLF); Clinical Research (LQ); Social and Epidemiological Research Department (BF, JR); Schizophrenia Division and Complex Mental Illness Program, Centre for Addiction and Mental Health (CAMH), Toronto, Canada (TPG); Addiction Policy, Dalla Lana School of Public Health (JR); Institute of Medical Science, University of Toronto, Faculty of Medicine (BF, JR); Department of Psychiatry, University of Toronto, Toronto, Canada (BF, TPG, JR, PS); Institute of Clinical Psychology and Psychotherapy & Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universität Dresden, Dresden, Germany (JR); Addictions Division, CAMH (PS, BLF); Department of Family and Community Medicine, University of Toronto, Toronto (PS); Centre for Applied Research in Mental Health & Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada (BF); and Chemistry and Drug Metabolism, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore, MD (AJB, MAH).

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http://dx.doi.org/10.1097/ADM.0000000000000229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586546PMC
April 2017

Corticotropin-releasing hormone and dopamine release in healthy individuals.

Psychoneuroendocrinology 2017 02 1;76:192-196. Epub 2016 Dec 1.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, 250 College St., Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2016.11.034DOI Listing
February 2017

Effects of varenicline on motor cortical plasticity in non-smokers with schizophrenia.

Schizophr Res 2016 12 6;178(1-3):50-55. Epub 2016 Sep 6.

Schizophrenia Division, Centre for Addiction and Mental Health, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.08.031DOI Listing
December 2016

Cannabis and psychosis: understanding the smoke signals.

Lancet Psychiatry 2016 10 23;3(10):909-910. Epub 2016 Aug 23.

Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, Ontario Canada.

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http://dx.doi.org/10.1016/S2215-0366(16)30230-9DOI Listing
October 2016

Integrated Care Pathways for Schizophrenia: A Scoping Review.

Adm Policy Ment Health 2016 09;43(5):760-767

Complex Mental Illness Program, Toronto Centre for Addiction and Mental Health, 1001 Queen St. W., Unit 2-1, #161, Toronto, ON, M6J 1H1, Canada.

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http://dx.doi.org/10.1007/s10488-015-0696-zDOI Listing
September 2016

Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking.

Pharmacol Biochem Behav 2016 09 11;148:1-7. Epub 2016 May 11.

Center for Tobacco Control Research and Education, University of California San Francisco, San Francisco, CA, USA; Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972680PMC
September 2016

Does cannabis use moderate smoking cessation outcomes in treatment-seeking tobacco smokers? Analysis from a large multi-center trial.

Am J Addict 2016 06 17;25(4):291-6. Epub 2016 May 17.

The Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/ajad.12382DOI Listing
June 2016

The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio.

Nicotine Tob Res 2016 Apr 11;18(4):491-5. Epub 2015 Jun 11.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1093/ntr/ntv125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220835PMC
April 2016

Deficits in GABAA receptor function and working memory in non-smokers with schizophrenia.

Schizophr Res 2016 Mar 18;171(1-3):125-30. Epub 2016 Jan 18.

Schizophrenia Division, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, 250 College Street, Toronto, ON M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.schres.2016.01.008DOI Listing
March 2016

Co-morbid tobacco use disorder and depression: A re-evaluation of smoking cessation therapy in depressed smokers.

Am J Addict 2015 Dec 10;24(8):687-94. Epub 2015 Sep 10.

Biobehavioural Addictions and Concurrent Disorders Research Laboratory (BACDRL), Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.

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http://dx.doi.org/10.1111/ajad.12277DOI Listing
December 2015

Training in Substance-Related and Addictive Disorders, Part 2: Updated Curriculum Guidelines.

Can J Psychiatry 2015 Dec;60(12):1-12

Professor and Head, Addiction Division, Department of Psychiatry, University of Calgary, Calgary, Alberta; Consultant, Addiction Centre, Foothills Medical Centre, Calgary, Alberta.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679171PMC
December 2015

Training in Substance-Related and Addictive Disorders, Part 1: Overview of Clinical Practice and General Recommendations.

Can J Psychiatry 2015 Dec;60(12):1-9

Professor and Head, Addiction Division, Department of Psychiatry, University of Calgary, Calgary, Alberta; Consultant, Addiction Centre, Foothills Medical Centre, Calgary, Alberta.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679170PMC
December 2015

Relationship between tobacco and cannabis use status in outpatients with schizophrenia.

Am J Addict 2014 Mar-Apr;23(2):170-5. Epub 2013 Aug 31.

The Institute of Medical Sciences (IMS), University of Toronto, Toronto, Ontario, Canada; Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1521-0391.2013.12084.xDOI Listing
October 2015

Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation.

Cancer Epidemiol Biomarkers Prev 2015 Aug 26;24(8):1239-46. Epub 2015 May 26.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada. Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-1381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526326PMC
August 2015

Measuring cigarette smoking-induced cortical dopamine release: A [¹¹C]FLB-457 PET study.

Neuropsychopharmacology 2015 May 15;40(6):1417-27. Epub 2014 Dec 15.

1] Research Imaging Centre (RIC), Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada [2] Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://www.nature.com/articles/npp2014327
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http://dx.doi.org/10.1038/npp.2014.327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397400PMC
May 2015

An association between the use of hypnotics and quit status in the treatment of nicotine dependence with varenicline in bipolar disorder.

J Clin Psychopharmacol 2015 Apr;35(2):199-200

Department of Psychiatry Western Psychiatric Institute and Clinic University of Pittsburgh Medical Center University of Pittsburgh School of Medicine Pittsburgh, PA Department of Psychiatry Centre for Addiction and Mental Health University of Toronto Toronto, Ontario, Canada Department of Psychiatry Western Psychiatric Institute and Clinic University of Pittsburgh School of Medicine Pittsburgh, PA Department of Psychiatry Western Psychiatric Institute and Clinic University of Pittsburgh Medical Center University of Pittsburgh School of Medicine Pittsburgh, PA

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http://dx.doi.org/10.1097/JCP.0000000000000272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344405PMC
April 2015

Minimal evidence that untreated psychosis damages brain structures: a systematic review.

Schizophr Res 2015 Mar 30;162(1-3):222-33. Epub 2015 Jan 30.

Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario M5T 1R8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.01.021DOI Listing
March 2015

Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial.

Lancet Respir Med 2015 Feb 12;3(2):131-138. Epub 2015 Jan 12.

Centre for Addiction and Mental Health and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/S2213-2600(14)70294-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480925PMC
February 2015

Circumspectives: the promise of ketamine.

Neuropsychopharmacology 2015 Jan;40(2):257-8

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/npp.2014.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443969PMC
January 2015

A review of drug policy in the Golden Crescent: towards the development of more effective solutions.

Asian J Psychiatr 2014 Dec 12;12:31-5. Epub 2014 Jul 12.

Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Department of Psychiatry, University of Toronto, Toronto, ON, Canada M5T 1R8. Electronic address:

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http://dx.doi.org/10.1016/j.ajp.2014.07.001DOI Listing
December 2014

Deep repetitive transcranial magnetic stimulation for smoking cessation: is going deeper better?

Biol Psychiatry 2014 Nov;76(9):678-80

Biobehavioural Addictions and Concurrent Disorders Laboratory, Schizophrenia Division, University of Toronto, Toronto, Canada.; Department of Psychiatry, Division of Brain and Therapeutics, University of Toronto, Toronto, Canada.. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.08.003DOI Listing
November 2014

The role of untreated psychosis in neurodegeneration: a review of hypothesized mechanisms of neurotoxicity in first-episode psychosis.

Can J Psychiatry 2014 Oct;59(10):513-7

Medical Director and Director of Health Equity, Centre for Addiction and Mental Health, Toronto, Ontario; Co-Director of Equity, Gender, and Population Psychiatry and Professor, Department of Psychiatry, University of Toronto, Toronto, Ontario.

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http://journals.sagepub.com/doi/10.1177/070674371405901003
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197784PMC
http://dx.doi.org/10.1177/070674371405901003DOI Listing
October 2014

Known and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokers.

Cancer Epidemiol Biomarkers Prev 2014 Sep 10;23(9):1773-82. Epub 2014 Jul 10.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada. Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154993PMC
September 2014

Cognitive remediation for individuals with psychosis in a supported education setting: a randomized controlled trial.

Schizophr Res 2014 Aug 2;157(1-3):90-8. Epub 2014 Jun 2.

Toronto Centre for Addiction and Mental Health, 1001 Queen St. W., Toronto, Ontario M6J 1H1 Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.05.007DOI Listing
August 2014

Neurocognitive endophenotypes in schizophrenia: modulation by nicotinic receptor systems.

Prog Neuropsychopharmacol Biol Psychiatry 2014 Jul 19;52:79-85. Epub 2013 Jul 19.

The Institute of Medical Sciences (IMS), University of Toronto, Toronto, Ontario Canada; Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), University of Toronto, Toronto, Ontario Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario Canada; Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, Ontario Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2013.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851927PMC
July 2014

Varenicline for smoking cessation in bipolar disorder: a randomized, double-blind, placebo-controlled study.

J Clin Psychiatry 2014 Jul;75(7):765-72

Comprehensive Recovery Services, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O'Hara St, Pittsburgh, PA 15213-2593

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http://dx.doi.org/10.4088/JCP.13m08756DOI Listing
July 2014

The relationship between the nicotine metabolite ratio and three self-report measures of nicotine dependence across sex and race.

Psychopharmacology (Berl) 2014 Jun 9;231(12):2515-23. Epub 2014 Jan 9.

Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, 4th Floor, Philadelphia, PA, 19104, USA,

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http://dx.doi.org/10.1007/s00213-013-3421-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040302PMC
June 2014

Testing a modification of cognitive adaptation training: streamlining the model for broader implementation.

Schizophr Res 2014 Jun 29;156(1):46-50. Epub 2014 Apr 29.

University of Texas, San Antonio, Department of Psychiatry, 7703 Floyd Curl Dr, San Antonio, TX 78229, United States.

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http://dx.doi.org/10.1016/j.schres.2014.03.026DOI Listing
June 2014

Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment.

Drug Alcohol Depend 2014 Mar 25;136:36-42. Epub 2013 Dec 25.

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine and Michael E. DeBakey VA Medical Center, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2013.12.007DOI Listing
March 2014

Heightened D3 dopamine receptor levels in cocaine dependence and contributions to the addiction behavioral phenotype: a positron emission tomography study with [11C]-+-PHNO.

Neuropsychopharmacology 2014 Jan 7;39(2):311-8. Epub 2013 Aug 7.

1] Addiction Imaging Research Group, Centre for Addiction and Mental Health, Toronto, ON, Canada [2] Research Imaging Centre and Vivian M Rakoff PET Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada [3] Human Brain Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada [4] Campbell Family Mental Health Research Institute, Toronto, ON, Canada [5] Division of Addictions, Centre for Addiction and Mental Health, Toronto, ON, Canada [6] Division of Schizophrenia, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/npp.2013.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870773PMC
January 2014

Elevation of dopamine induced by cigarette smoking: novel insights from a [11C]-+-PHNO PET study in humans.

Neuropsychopharmacology 2014 Jan 19;39(2):415-24. Epub 2013 Aug 19.

1] Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada [2] Department of Psychiatry, Division of Brain and Therapeutics, University of Toronto, Toronto, ON, Canada [3] Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada [4] Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada [5] Addiction Imaging Research Group, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/npp.2013.209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870776PMC
January 2014

Effect of COMT Val(158)Met genotype on nicotine withdrawal-related cognitive dysfunction in smokers with and without schizophrenia.

Schizophr Res 2013 Nov 29;150(2-3):602-3. Epub 2013 Sep 29.

Division of Brain and Therapeutics, Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Schizophrenia Division, Complex Mental Illness, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346073PMC
November 2013

Bipolar disorder and co-occurring cannabis use disorders: characteristics, co-morbidities and clinical correlates.

Psychiatry Res 2013 Oct 10;209(3):459-65. Epub 2013 Jan 10.

Social Aetiology of Mental Illness (SAMI) CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Addictions Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2012.12.014DOI Listing
October 2013

Cannabis use and cannabis use disorders among individuals with mental illness.

Compr Psychiatry 2013 Aug 31;54(6):589-98. Epub 2013 Jan 31.

Social Aetiology of Mental Illness CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.comppsych.2012.12.021DOI Listing
August 2013

Brain stimulation methods to treat tobacco addiction.

Brain Stimul 2013 May 9;6(3):221-30. Epub 2012 Jul 9.

Biobehavioural Addictions and Concurrent Disorders Research Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.brs.2012.06.008DOI Listing
May 2013

Effects of cannabis use status on cognitive function, in males with schizophrenia.

Psychiatry Res 2013 Apr 13;206(2-3):158-65. Epub 2012 Dec 13.

Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.psychres.2012.11.019DOI Listing
April 2013

Dopamine response to psychosocial stress in chronic cannabis users: a PET study with [11C]-+-PHNO.

Neuropsychopharmacology 2013 Mar 8;38(4):673-82. Epub 2012 Nov 8.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/npp.2012.232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572464PMC
March 2013

Effects of tobacco smoking on neuropsychological function in schizophrenia in comparison to other psychiatric disorders and non-psychiatric controls.

Am J Addict 2013 Jan;22(1):46-53

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1521-0391.2013.00313.xDOI Listing
January 2013

Treatment of tobacco dependence in people with mental health and addictive disorders.

Curr Psychiatry Rep 2012 Oct;14(5):478-85

Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s11920-012-0299-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722553PMC
October 2012

Reproducibility of the nicotine metabolite ratio in cigarette smokers.

Cancer Epidemiol Biomarkers Prev 2012 Jul 2;21(7):1105-14. Epub 2012 May 2.

Center for Tobacco Control Research and Education, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-12-0236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392523PMC
July 2012

Smoking cue reactivity in adult smokers with and without depression: a pilot study.

Am J Addict 2012 Mar-Apr;21(2):136-44

Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA.

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http://dx.doi.org/10.1111/j.1521-0391.2011.00203.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647350PMC
June 2012

A randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of varenicline for smoking cessation in patients with schizophrenia or schizoaffective disorder.

J Clin Psychiatry 2012 May;73(5):654-60

Division of Addiction Psychiatry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.

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http://dx.doi.org/10.4088/JCP.11m07522DOI Listing
May 2012

A Preliminary Feasibility Study of Varenicline for Smoking Cessation in Bipolar Disorder.

J Dual Diagn 2012 Apr 20;8(2):131-132. Epub 2012 Mar 20.

Schizophrenia Program, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1080/15504263.2012.671067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435104PMC
April 2012

A review of neurobiological vulnerability factors and treatment implications for comorbid tobacco dependence in schizophrenia.

Ann N Y Acad Sci 2012 Feb 30;1248:89-106. Epub 2011 Nov 30.

Addiction Psychiatry Program, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1111/j.1749-6632.2011.06261.x
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http://dx.doi.org/10.1111/j.1749-6632.2011.06261.xDOI Listing
February 2012

Effects of cigarette smoking status on delay discounting in schizophrenia and healthy controls.

Addict Behav 2012 Jan 8;37(1):67-72. Epub 2011 Sep 8.

Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.addbeh.2011.08.012DOI Listing
January 2012

A Review of Smoking Cessation in Bipolar Disorder: Implications for Future Research.

J Dual Diagn 2012 Jan 11;8(2):126-130. Epub 2012 May 11.

Schizophrenia Program, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1080/15504263.2012.671717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378056PMC
January 2012

Repetitive transcranial magnetic stimulation and drug addiction.

Int Rev Psychiatry 2011 Oct;23(5):454-66

Schizophrenia Program, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3109/09540261.2011.618827DOI Listing
October 2011

Neuropsychological performance in patients with schizophrenia and controls as a function of cigarette smoking status.

Psychiatry Res 2011 Aug 12;188(3):320-6. Epub 2011 Jun 12.

Centre for Addiction and Mental Health (CAMH), Schizophrenia Program; Division of Addiction Psychiatry, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.psychres.2011.05.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346074PMC
August 2011

Pharmacogenetics of alcohol, nicotine and drug addiction treatments.

Addict Biol 2011 Jul 1;16(3):357-76. Epub 2011 Mar 1.

Centre for Addiction and Mental Health, Pharmacogenetics Research Clinic, 250 College Street, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1111/j.1369-1600.2010.00287.x
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http://dx.doi.org/10.1111/j.1369-1600.2010.00287.xDOI Listing
July 2011

The effects of cannabis use on neurocognition in schizophrenia: a meta-analysis.

Schizophr Res 2011 May 21;128(1-3):111-6. Epub 2011 Mar 21.

The Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.schres.2011.02.017DOI Listing
May 2011

Impact of a smoke-free policy in a large psychiatric hospital on staff attitudes and patient behavior.

Gen Hosp Psychiatry 2010 Nov-Dec;32(6):623-30. Epub 2010 Oct 14.

Centre for Addiction and Mental Health, Toronto, Canada M5S 2S1.

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http://dx.doi.org/10.1016/j.genhosppsych.2010.08.005DOI Listing
April 2011

Differences in smoking expectancies in smokers with and without a history of major depression.

Addict Behav 2011 Apr 28;36(4):434-7. Epub 2010 Dec 28.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA.

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http://dx.doi.org/10.1016/j.addbeh.2010.12.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052745PMC
April 2011

Individualized smoking cessation treatment in an outpatient setting: Predictors of outcome in a sample with psychiatric and addictions co-morbidity.

Addict Behav 2010 Sep 10;35(9):811-7. Epub 2010 Apr 10.

Addictions Program and Nicotine Dependence Clinic, Centre for Addiction and Mental Health, Toronto, ON, Canada M5S 2S1.

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http://dx.doi.org/10.1016/j.addbeh.2010.03.020DOI Listing
September 2010

Changes in smoking expectancies in abstinent, reducing, and non-abstinent participants during a pharmacological trial for smoking cessation.

Nicotine Tob Res 2010 Sep 19;12(9):937-43. Epub 2010 Jul 19.

Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, 34 Park Street, SAC, Room S-211, New Haven, CT 06519, USA.

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http://dx.doi.org/10.1093/ntr/ntq120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928936PMC
September 2010