Toni-Kim Clarke

Toni-Kim Clarke

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Toni-Kim Clarke

Toni-Kim Clarke

Publications by authors named "Toni-Kim Clarke"

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Insulin resistance: Genetic associations with depression and cognition in population based cohorts.

Exp Neurol 2019 Jun 6;316:20-26. Epub 2019 Apr 6.

Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK; Department of Psychology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.expneurol.2019.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503941PMC
June 2019

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Authors:
Eli A Stahl Gerome Breen Andreas J Forstner Andrew McQuillin Stephan Ripke Vassily Trubetskoy Manuel Mattheisen Yunpeng Wang Jonathan R I Coleman Héléna A Gaspar Christiaan A de Leeuw Stacy Steinberg Jennifer M Whitehead Pavlides Maciej Trzaskowski Enda M Byrne Tune H Pers Peter A Holmans Alexander L Richards Liam Abbott Esben Agerbo Huda Akil Diego Albani Ney Alliey-Rodriguez Thomas D Als Adebayo Anjorin Verneri Antilla Swapnil Awasthi Judith A Badner Marie Bækvad-Hansen Jack D Barchas Nicholas Bass Michael Bauer Richard Belliveau Sarah E Bergen Carsten Bøcker Pedersen Erlend Bøen Marco P Boks James Boocock Monika Budde William Bunney Margit Burmeister Jonas Bybjerg-Grauholm William Byerley Miquel Casas Felecia Cerrato Pablo Cervantes Kimberly Chambert Alexander W Charney Danfeng Chen Claire Churchhouse Toni-Kim Clarke William Coryell David W Craig Cristiana Cruceanu David Curtis Piotr M Czerski Anders M Dale Simone de Jong Franziska Degenhardt Jurgen Del-Favero J Raymond DePaulo Srdjan Djurovic Amanda L Dobbyn Ashley Dumont Torbjørn Elvsåshagen Valentina Escott-Price Chun Chieh Fan Sascha B Fischer Matthew Flickinger Tatiana M Foroud Liz Forty Josef Frank Christine Fraser Nelson B Freimer Louise Frisén Katrin Gade Diane Gage Julie Garnham Claudia Giambartolomei Marianne Giørtz Pedersen Jaqueline Goldstein Scott D Gordon Katherine Gordon-Smith Elaine K Green Melissa J Green Tiffany A Greenwood Jakob Grove Weihua Guan José Guzman-Parra Marian L Hamshere Martin Hautzinger Urs Heilbronner Stefan Herms Maria Hipolito Per Hoffmann Dominic Holland Laura Huckins Stéphane Jamain Jessica S Johnson Anders Juréus Radhika Kandaswamy Robert Karlsson James L Kennedy Sarah Kittel-Schneider James A Knowles Manolis Kogevinas Anna C Koller Ralph Kupka Catharina Lavebratt Jacob Lawrence William B Lawson Markus Leber Phil H Lee Shawn E Levy Jun Z Li Chunyu Liu Susanne Lucae Anna Maaser Donald J MacIntyre Pamela B Mahon Wolfgang Maier Lina Martinsson Steve McCarroll Peter McGuffin Melvin G McInnis James D McKay Helena Medeiros Sarah E Medland Fan Meng Lili Milani Grant W Montgomery Derek W Morris Thomas W Mühleisen Niamh Mullins Hoang Nguyen Caroline M Nievergelt Annelie Nordin Adolfsson Evaristus A Nwulia Claire O'Donovan Loes M Olde Loohuis Anil P S Ori Lilijana Oruc Urban Ösby Roy H Perlis Amy Perry Andrea Pfennig James B Potash Shaun M Purcell Eline J Regeer Andreas Reif Céline S Reinbold John P Rice Fabio Rivas Margarita Rivera Panos Roussos Douglas M Ruderfer Euijung Ryu Cristina Sánchez-Mora Alan F Schatzberg William A Scheftner Nicholas J Schork Cynthia Shannon Weickert Tatyana Shehktman Paul D Shilling Engilbert Sigurdsson Claire Slaney Olav B Smeland Janet L Sobell Christine Søholm Hansen Anne T Spijker David St Clair Michael Steffens John S Strauss Fabian Streit Jana Strohmaier Szabolcs Szelinger Robert C Thompson Thorgeir E Thorgeirsson Jens Treutlein Helmut Vedder Weiqing Wang Stanley J Watson Thomas W Weickert Stephanie H Witt Simon Xi Wei Xu Allan H Young Peter Zandi Peng Zhang Sebastian Zöllner Rolf Adolfsson Ingrid Agartz Martin Alda Lena Backlund Bernhard T Baune Frank Bellivier Wade H Berrettini Joanna M Biernacka Douglas H R Blackwood Michael Boehnke Anders D Børglum Aiden Corvin Nicholas Craddock Mark J Daly Udo Dannlowski Tõnu Esko Bruno Etain Mark Frye Janice M Fullerton Elliot S Gershon Michael Gill Fernando Goes Maria Grigoroiu-Serbanescu Joanna Hauser David M Hougaard Christina M Hultman Ian Jones Lisa A Jones René S Kahn George Kirov Mikael Landén Marion Leboyer Cathryn M Lewis Qingqin S Li Jolanta Lissowska Nicholas G Martin Fermin Mayoral Susan L McElroy Andrew M McIntosh Francis J McMahon Ingrid Melle Andres Metspalu Philip B Mitchell Gunnar Morken Ole Mors Preben Bo Mortensen Bertram Müller-Myhsok Richard M Myers Benjamin M Neale Vishwajit Nimgaonkar Merete Nordentoft Markus M Nöthen Michael C O'Donovan Ketil J Oedegaard Michael J Owen Sara A Paciga Carlos Pato Michele T Pato Danielle Posthuma Josep Antoni Ramos-Quiroga Marta Ribasés Marcella Rietschel Guy A Rouleau Martin Schalling Peter R Schofield Thomas G Schulze Alessandro Serretti Jordan W Smoller Hreinn Stefansson Kari Stefansson Eystein Stordal Patrick F Sullivan Gustavo Turecki Arne E Vaaler Eduard Vieta John B Vincent Thomas Werge John I Nurnberger Naomi R Wray Arianna Di Florio Howard J Edenberg Sven Cichon Roel A Ophoff Laura J Scott Ole A Andreassen John Kelsoe Pamela Sklar

Nat Genet 2019 05 1;51(5):793-803. Epub 2019 May 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://www.nature.com/articles/s41588-019-0397-8
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http://dx.doi.org/10.1038/s41588-019-0397-8DOI Listing
May 2019

Pharmaco-epidemiology of antidepressant exposure in a UK cohort record-linkage study.

J Psychopharmacol 2019 Apr 27;33(4):482-493. Epub 2019 Feb 27.

1 Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1177/0269881119827888DOI Listing
April 2019

Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank.

Biol Psychiatry 2019 Apr 22. Epub 2019 Apr 22.

Division of Psychiatry, Royal Edinburgh Hospital, Edinburgh, UK; The Patrick Wild Centre, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.biopsych.2019.04.013DOI Listing
April 2019

Author Correction: Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

Nat Genet 2019 03;51(3):577

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41588-019-0357-3DOI Listing
March 2019

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.

Am J Psychiatry 2019 Feb 19;176(2):107-118. Epub 2018 Oct 19.

From the Department of Psychiatry and the Institute for Genomic Medicine, University of California San Diego, La Jolla; 23andMe, Inc., Mountain View, Calif.; the Division of Psychiatry, the Department of Psychology, and the Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, U.K.; the Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis; and the Translational Research Laboratories, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1176/appi.ajp.2018.18040369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365681PMC
February 2019

Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

Transl Psychiatry 2019 02 4;9(1):14. Epub 2019 Feb 4.

Medical Genetics Section, University of Edinburgh, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41398-018-0360-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361928PMC
February 2019

OPRD1 Genetic Variation and Human Disease.

Handb Exp Pharmacol 2018;247:131-145

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1007/164_2016_112DOI Listing
January 2019

A validation of the diathesis-stress model for depression in Generation Scotland.

Transl Psychiatry 2019 01 18;9(1):25. Epub 2019 Jan 18.

Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41398-018-0356-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338746PMC
January 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Epigenetic signatures of starting and stopping smoking.

EBioMedicine 2018 Nov 30;37:214-220. Epub 2018 Oct 30.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.10.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286188PMC
November 2018

Pharmacogenetics of Opioid Use Disorder Treatment.

CNS Drugs 2018 04;32(4):305-320

Translational Research Laboratories, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 South 31st Street, Room 2207, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s40263-018-0513-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935553PMC
April 2018

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

Nat Genet 2018 01 18;50(1):6-11. Epub 2017 Dec 18.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41588-017-0013-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985926PMC
January 2018

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.

Authors:
Nese Direk Stephanie Williams Jennifer A Smith Stephan Ripke Tracy Air Azmeraw T Amare Najaf Amin Bernhard T Baune David A Bennett Douglas H R Blackwood Dorret Boomsma Gerome Breen Henriette N Buttenschøn Enda M Byrne Anders D Børglum Enrique Castelao Sven Cichon Toni-Kim Clarke Marilyn C Cornelis Udo Dannlowski Philip L De Jager Ayse Demirkan Enrico Domenici Cornelia M van Duijn Erin C Dunn Johan G Eriksson Tonu Esko Jessica D Faul Luigi Ferrucci Myriam Fornage Eco de Geus Michael Gill Scott D Gordon Hans Jörgen Grabe Gerard van Grootheest Steven P Hamilton Catharina A Hartman Andrew C Heath Karin Hek Albert Hofman Georg Homuth Carsten Horn Jouke Jan Hottenga Sharon L R Kardia Stefan Kloiber Karestan Koenen Zoltán Kutalik Karl-Heinz Ladwig Jari Lahti Douglas F Levinson Cathryn M Lewis Glyn Lewis Qingqin S Li David J Llewellyn Susanne Lucae Kathryn L Lunetta Donald J MacIntyre Pamela Madden Nicholas G Martin Andrew M McIntosh Andres Metspalu Yuri Milaneschi Grant W Montgomery Ole Mors Thomas H Mosley Joanne M Murabito Bertram Müller-Myhsok Markus M Nöthen Dale R Nyholt Michael C O'Donovan Brenda W Penninx Michele L Pergadia Roy Perlis James B Potash Martin Preisig Shaun M Purcell Jorge A Quiroz Katri Räikkönen John P Rice Marcella Rietschel Margarita Rivera Thomas G Schulze Jianxin Shi Stanley Shyn Grant C Sinnamon Johannes H Smit Jordan W Smoller Harold Snieder Toshiko Tanaka Katherine E Tansey Alexander Teumer Rudolf Uher Daniel Umbricht Sandra Van der Auwera Erin B Ware David R Weir Myrna M Weissman Gonneke Willemsen Jingyun Yang Wei Zhao Henning Tiemeier Patrick F Sullivan

Biol Psychiatry 2017 09 8;82(5):322-329. Epub 2016 Dec 8.

Department of Psychiatry, Genomic Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Center for Psychiatric Genomics, Genomic Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1016/j.biopsych.2016.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462867PMC
September 2017

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 2;174(3):227-234. Epub 2016 Aug 2.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.32478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363226PMC
April 2017

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder.

Biol Psychiatry 2017 02 2;81(4):336-346. Epub 2016 May 2.

Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom; Generation Scotland, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2016.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262437PMC
February 2017

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

EBioMedicine 2016 Dec 4;14:161-167. Epub 2016 Nov 4.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.ebiom.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161419PMC
December 2016

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.

Authors:
Gunter Schumann Chunyu Liu Paul O'Reilly He Gao Parkyong Song Bing Xu Barbara Ruggeri Najaf Amin Tianye Jia Sarah Preis Marcelo Segura Lepe Shizuo Akira Caterina Barbieri Sebastian Baumeister Stephane Cauchi Toni-Kim Clarke Stefan Enroth Krista Fischer Jenni Hällfors Sarah E Harris Saskia Hieber Edith Hofer Jouke-Jan Hottenga Åsa Johansson Peter K Joshi Niina Kaartinen Jaana Laitinen Rozenn Lemaitre Anu Loukola Jian'an Luan Leo-Pekka Lyytikäinen Massimo Mangino Ani Manichaikul Hamdi Mbarek Yuri Milaneschi Alireza Moayyeri Kenneth Mukamal Christopher Nelson Jennifer Nettleton Eemil Partinen Rajesh Rawal Antonietta Robino Lynda Rose Cinzia Sala Takashi Satoh Reinhold Schmidt Katharina Schraut Robert Scott Albert Vernon Smith John M Starr Alexander Teumer Stella Trompet André G Uitterlinden Cristina Venturini Anne-Claire Vergnaud Niek Verweij Veronique Vitart Dragana Vuckovic Juho Wedenoja Loic Yengo Bing Yu Weihua Zhang Jing Hua Zhao Dorret I Boomsma John Chambers Daniel I Chasman Toniolo Daniela Eco de Geus Ian Deary Johan G Eriksson Tõnu Esko Volker Eulenburg Oscar H Franco Philippe Froguel Christian Gieger Hans J Grabe Vilmundur Gudnason Ulf Gyllensten Tamara B Harris Anna-Liisa Hartikainen Andrew C Heath Lynne Hocking Albert Hofman Cornelia Huth Marjo-Riitta Jarvelin J Wouter Jukema Jaakko Kaprio Jaspal S Kooner Zoltan Kutalik Jari Lahti Claudia Langenberg Terho Lehtimäki Yongmei Liu Pamela A F Madden Nicholas Martin Alanna Morrison Brenda Penninx Nicola Pirastu Bruce Psaty Olli Raitakari Paul Ridker Richard Rose Jerome I Rotter Nilesh J Samani Helena Schmidt Tim D Spector David Stott David Strachan Ioanna Tzoulaki Pim van der Harst Cornelia M van Duijn Pedro Marques-Vidal Peter Vollenweider Nicholas J Wareham John B Whitfield James Wilson Bruce Wolffenbuttel Georgy Bakalkin Evangelos Evangelou Yun Liu Kenneth M Rice Sylvane Desrivières Steven A Kliewer David J Mangelsdorf Christian P Müller Daniel Levy Paul Elliott

Proc Natl Acad Sci U S A 2016 12 28;113(50):14372-14377. Epub 2016 Nov 28.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London W2 1PG, United Kingdom;

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http://www.pnas.org/content/113/50/14372.full.pdf
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http://dx.doi.org/10.1073/pnas.1611243113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167198PMC
December 2016

Polygenic risk for coronary artery disease is associated with cognitive ability in older adults.

Int J Epidemiol 2016 Jan 28. Epub 2016 Jan 28.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK Department of Psychology, University of Edinburgh, Edinburgh, UK,

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http://dx.doi.org/10.1093/ije/dyv354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864876PMC
January 2016

Characterization of genetic variation in the VGLL4 gene in anorexia nervosa.

Psychiatr Genet 2014 Aug;24(4):183-4

aDepartment of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia bDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania cDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland dDepartment of Psychiatry, University of Minnesota, Minneapolis, Minnesota eNew York Presbyterian Hospital-Westchester Division, Weill Medical College of Cornell, University, White Plains, New York fEating Recovery Center, Denver, Colorado gDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina hNeuropsychiatric Research Institute, Fargo iDepartment of Clinical Neuroscience, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota jDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles kCenter for Health Sciences, SRI International, Menlo Park lDepartment of Psychiatry, University of California at San Diego, San Diego mScripps Genomic Medicine, The Scripps Research Institute, La Jolla, California nDepartment of Psychology, Florida State University, Tallahassee, Florida oDepartment of Psychology, Michigan State University, East Lansing, Michigan pClinical Psychology Program, American School of Professional Psychology at Argosy University, Washington, District of Columbia, USA qRoseneck Hospital for Behavioral Medicine, Prien rDepartment of Psychiatry, University of Munich (LMU), Munich, Germany sCenter for Addiction and Mental Health tDepartment of Psychiatry, Toronto General Hospital, University Health Network uDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada vDepartment of Psychiatry, Neurobiology, Pharmacology, and Biotechnology, University of Pisa, Pisa, Italy wDepartment of Academic Psychiatry, Bermondsey Wing Guys Hospital, University of London, London, UK xBrain Mind Institute EPFL - Lausanne and Center for Psyc

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http://dx.doi.org/10.1097/YPG.0000000000000040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104366PMC
August 2014

The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction.

Ann Hum Genet 2014 Jan 25;78(1):33-9. Epub 2013 Nov 25.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.

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http://doi.wiley.com/10.1111/ahg.12046
Publisher Site
http://dx.doi.org/10.1111/ahg.12046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013426PMC
January 2014

An intronic variant in OPRD1 predicts treatment outcome for opioid dependence in African-Americans.

Neuropsychopharmacology 2013 Sep 23;38(10):2003-10. Epub 2013 Apr 23.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2013.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746708PMC
September 2013

Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.

Addict Biol 2013 Jul 25;18(4):702-8. Epub 2011 Jul 25.

Psychiatric Pharmacogenetics Laboratory Center for Neurobiology and Behavior Treatment Research Center Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00346.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223560PMC
July 2013

Genetic and environmental determinants of stress responding.

Alcohol Res 2012 ;34(4):484-94

Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860390PMC
July 2013

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

Neurosci Lett 2013 May 20;542:71-5. Epub 2013 Feb 20.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2013.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640707PMC
May 2013

Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.

Neurosci Lett 2012 Nov 20;531(1):46-51. Epub 2012 Sep 20.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2012.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895491PMC
November 2012

Association study of the β-arrestin 2 gene (ARRB2) with opioid and cocaine dependence in a European-American population.

Psychiatr Genet 2012 Jun;22(3):141-5

Translational Research Laboratory, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, 125 S. 31st St, School of Medicine, Rm. 2109, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/YPG.0b013e3283539528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920286PMC
June 2012

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.

Authors:
Gunter Schumann Lachlan J Coin Anbarasu Lourdusamy Pimphen Charoen Karen H Berger David Stacey Sylvane Desrivières Fazil A Aliev Anokhi A Khan Najaf Amin Yurii S Aulchenko Georgy Bakalkin Stephan J Bakker Beverley Balkau Joline W Beulens Ainhoa Bilbao Rudolf A de Boer Delphine Beury Michiel L Bots Elemi J Breetvelt Stéphane Cauchi Christine Cavalcanti-Proença John C Chambers Toni-Kim Clarke Norbert Dahmen Eco J de Geus Danielle Dick Francesca Ducci Alanna Easton Howard J Edenberg Tõnu Esko Tõnu Esk Alberto Fernández-Medarde Tatiana Foroud Nelson B Freimer Jean-Antoine Girault Diederick E Grobbee Simonetta Guarrera Daniel F Gudbjartsson Anna-Liisa Hartikainen Andrew C Heath Victor Hesselbrock Albert Hofman Jouke-Jan Hottenga Matti K Isohanni Jaakko Kaprio Kay-Tee Khaw Brigitte Kuehnel Jaana Laitinen Stéphane Lobbens Jian'an Luan Massimo Mangino Matthieu Maroteaux Giuseppe Matullo Mark I McCarthy Christian Mueller Gerjan Navis Mattijs E Numans Alejandro Núñez Dale R Nyholt Charlotte N Onland-Moret Ben A Oostra Paul F O'Reilly Miklos Palkovits Brenda W Penninx Silvia Polidoro Anneli Pouta Inga Prokopenko Fulvio Ricceri Eugenio Santos Johannes H Smit Nicole Soranzo Kijoung Song Ulla Sovio Michael Stumvoll Ida Surakk Thorgeir E Thorgeirsson Unnur Thorsteinsdottir Claire Troakes Thorarinn Tyrfingsson Anke Tönjes Cuno S Uiterwaal Andre G Uitterlinden Pim van der Harst Yvonne T van der Schouw Oliver Staehlin Nicole Vogelzangs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth John B Whitfield Erich H Wichmann Gonneke Willemsen Jacqueline C Witteman Xin Yuan Guangju Zhai Jing H Zhao Weihua Zhang Nicholas G Martin Andres Metspalu Angela Doering James Scott Tim D Spector Ruth J Loos Dorret I Boomsma Vincent Mooser Leena Peltonen Kari Stefansson Cornelia M van Duijn Paolo Vineis Wolfgang H Sommer Jaspal S Kooner Rainer Spanagel Ulrike A Heberlein Marjo-Riitta Jarvelin Paul Elliott

Proc Natl Acad Sci U S A 2011 Apr 6;108(17):7119-24. Epub 2011 Apr 6.

Medical Research Council-Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, London SE5 8AF, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1017288108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084048PMC
April 2011

The genetics of alcoholism.

Curr Psychiatry Rep 2009 Oct;11(5):364-9

MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College, P. O. Box 80, London SE58AF, England.

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October 2009

Gene-environment interactions resulting in risk alcohol drinking behaviour are mediated by CRF and CRF1.

Pharmacol Biochem Behav 2009 Sep 3;93(3):230-6. Epub 2009 May 3.

Interdisciplinary Research Group Addiction and MRC SGDP Centre, Institute of Psychiatry at King's College London, UK.

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http://dx.doi.org/10.1016/j.pbb.2009.04.014DOI Listing
September 2009

An association of prodynorphin polymorphisms and opioid dependence in females in a Chinese population.

Addict Biol 2009 Jul 5;14(3):366-70. Epub 2009 Mar 5.

Section of Addiction Biology, Institute of Psychiatry, King's College, London, UK.

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http://dx.doi.org/10.1111/j.1369-1600.2009.00151.xDOI Listing
July 2009

HPA-axis activity in alcoholism: examples for a gene-environment interaction.

Addict Biol 2008 Mar 2;13(1):1-14. Epub 2007 Oct 2.

Section of Addiction Biology, Institute of Psychiatry, King's College, London, UK.

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http://dx.doi.org/10.1111/j.1369-1600.2007.00084.xDOI Listing
March 2008

The evolution of the vertebrate metzincins; insights from Ciona intestinalis and Danio rerio.

BMC Evol Biol 2007 Apr 17;7:63. Epub 2007 Apr 17.

Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1186/1471-2148-7-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867822PMC
April 2007