Tomoyuki Furuyashiki

Tomoyuki Furuyashiki

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Tomoyuki Furuyashiki

Tomoyuki Furuyashiki

Publications by authors named "Tomoyuki Furuyashiki"

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The Lacto-Tetrapeptide Gly-Thr-Trp-Tyr, β-Lactolin, Improves Spatial Memory Functions via Dopamine Release and D1 Receptor Activation in the Hippocampus.

Nutrients 2019 Oct 15;11(10). Epub 2019 Oct 15.

Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

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http://dx.doi.org/10.3390/nu11102469DOI Listing
October 2019

Leucine-Histidine Dipeptide Attenuates Microglial Activation and Emotional Disturbances Induced by Brain Inflammation and Repeated Social Defeat Stress.

Nutrients 2019 Sep 9;11(9). Epub 2019 Sep 9.

Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

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http://dx.doi.org/10.3390/nu11092161DOI Listing
September 2019

Roles of multiple lipid mediators in stress and depression.

Int Immunol 2019 Aug;31(9):579-587

Division of Pharmacology, Kobe University Graduate School of Medicine, Kusunoki-cho, Kobe, Hyogo, Japan.

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http://dx.doi.org/10.1093/intimm/dxz023DOI Listing
August 2019

Improvement of PTSD-like behavior by the forgetting effect of hippocampal neurogenesis enhancer memantine in a social defeat stress paradigm.

Mol Brain 2019 Aug 2;12(1):68. Epub 2019 Aug 2.

Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo, 156-8502, Japan.

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http://dx.doi.org/10.1186/s13041-019-0488-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676601PMC
August 2019

Social defeat stress induces phosphorylation of extracellular signal-regulated kinase in the leptomeninges in mice.

Neuropsychopharmacol Rep 2019 Jun 14;39(2):134-139. Epub 2019 Feb 14.

Division of Pharmacology, Graduate School of Medicine, Kobe University, Kobe, Japan.

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http://dx.doi.org/10.1002/npr2.12051DOI Listing
June 2019

Neural mechanisms underlying adaptive and maladaptive consequences of stress: Roles of dopaminergic and inflammatory responses.

Psychiatry Clin Neurosci 2019 Jun 19. Epub 2019 Jun 19.

Division of Pharmacology, Graduate School of Medicine, Kobe University, Kobe, Japan.

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http://dx.doi.org/10.1111/pcn.12901DOI Listing
June 2019

Tryptophan-Tyrosine Dipeptide, the Core Sequence of β-Lactolin, Improves Memory by Modulating the Dopamine System.

Nutrients 2019 Feb 6;11(2). Epub 2019 Feb 6.

Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

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http://dx.doi.org/10.3390/nu11020348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412195PMC
February 2019

The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation.

Neuron 2018 08 19;99(3):464-479.e7. Epub 2018 Jul 19.

Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe, Hyogo 650-0017, Japan; AMED-CREST, Chiyoda-ku, Tokyo 100-0004, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.06.035DOI Listing
August 2018

mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety.

Cell Rep 2016 11;17(9):2405-2417

Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.088DOI Listing
November 2016

Genetic Interactions among AMPK Catalytic Subunit Ssp2 and Glycogen Synthase Kinases Gsk3 and Gsk31 in Schizosaccharomyces Pombe.

Kobe J Med Sci 2016 Aug 3;62(3):E70-8. Epub 2016 Aug 3.

Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425143PMC
August 2016

Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism.

Kobe J Med Sci 2015 Oct 9;61(2):E54-63. Epub 2015 Oct 9.

Division of Pharmacology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.

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October 2015

Azoles activate Atf1-mediated transcription through MAP kinase pathway for antifungal effects in fission yeast.

Genes Cells 2015 Sep 23;20(9):695-705. Epub 2015 Jun 23.

Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe, 650-0017, Japan.

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http://dx.doi.org/10.1111/gtc.12263DOI Listing
September 2015

CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease.

Neurobiol Aging 2015 Mar 4;36(3):1356-68. Epub 2014 Dec 4.

Institute of Bioinformatics and Biosignal Transduction, National Cheng Kung University, Tainan, Taiwan; Institute of Basic Medical Sciences, National Cheng Kung University, Tainan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan; Infectious Disease and Signaling Research Center, National Cheng Kung University, Tainan, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.11.020DOI Listing
March 2015

[Roles of inflammation-related molecules in emotional changes induced by repeated stress].

Nihon Shinkei Seishin Yakurigaku Zasshi 2014 Aug;34(4):109-15

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August 2014

EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination.

Genes Cells 2013 Oct 25;18(10):873-85. Epub 2013 Jul 25.

Department of Pharmacology, Kyoto University Graduate School of Medicine, Yoshida-konoe-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

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http://dx.doi.org/10.1111/gtc.12081DOI Listing
October 2013

Roles of dopamine and inflammation-related molecules in behavioral alterations caused by repeated stress.

J Pharmacol Sci 2012 15;120(2):63-9. Epub 2012 Sep 15.

Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1254/jphs.12r09cpDOI Listing
March 2013

Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells.

Blood 2013 Mar 11;121(11):1995-2007. Epub 2013 Jan 11.

Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, School of Medicine, Keio University, Tokyo, Japan.

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http://dx.doi.org/10.1182/blood-2012-06-437889DOI Listing
March 2013

Roles of dopamine and inflammation-related molecules in behavioral alterations caused by repeated stress.

J Pharmacol Sci 2012 15;120(2):63-9. Epub 2012 Sep 15.

Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1254/jphs.12r09cpDOI Listing
March 2013

Role of PGE-type receptor 4 in auditory function and noise-induced hearing loss in mice.

Neuropharmacology 2012 Mar 16;62(4):1841-7. Epub 2011 Dec 16.

Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kawaharacho 54, Shogoin, Sakyoku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.neuropharm.2011.12.007DOI Listing
March 2012

A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors.

Nat Neurosci 2012 Jan 15;15(3):373-80, S1-2. Epub 2012 Jan 15.

Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1038/nn.3020DOI Listing
January 2012

Central PGE2 exhibits anxiolytic-like activity via EP1 and EP4 receptors in a manner dependent on serotonin 5-HT1A, dopamine D1 and GABAA receptors.

FEBS Lett 2011 Jul 17;585(14):2357-62. Epub 2011 Jun 17.

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho Uji, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.febslet.2011.06.004DOI Listing
July 2011

Stress responses: the contribution of prostaglandin E(2) and its receptors.

Nat Rev Endocrinol 2011 Mar 30;7(3):163-75. Epub 2010 Nov 30.

Department of Pharmacology, Kyoto University Graduate School of Medicine, Yoshida-konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1038/nrendo.2010.194DOI Listing
March 2011

Fever, inflammation, pain and beyond: prostanoid receptor research during these 25 years.

FASEB J 2011 Mar;25(3):813-8

1 Department of Pharmacology, Kyoto University Graduate School of Medicine, Yoshida-konoe-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

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http://dx.doi.org/10.1096/fj.11-0302ufmDOI Listing
March 2011

Roles of prostaglandin E receptors in stress responses.

Curr Opin Pharmacol 2009 Feb 20;9(1):31-8. Epub 2009 Jan 20.

Department of Pharmacology, Kyoto University Graduate School of Medicine, Yoshida-konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.coph.2008.12.010DOI Listing
February 2009

Rat orbitofrontal cortex separately encodes response and outcome information during performance of goal-directed behavior.

J Neurosci 2008 May;28(19):5127-38

Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0319-08.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693204PMC
May 2008

Neural encoding in the orbitofrontal cortex related to goal-directed behavior.

Ann N Y Acad Sci 2007 Dec 13;1121:193-215. Epub 2007 Sep 13.

Johns Hopkins University, Department of Psychological and Brain Sciences, Baltimore, MD 21218, USA.

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http://dx.doi.org/10.1196/annals.1401.037DOI Listing
December 2007

Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1.

J Exp Med 2007 Nov 29;204(12):2865-74. Epub 2007 Oct 29.

Department of Pharmacology, Faculty of Medicine, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1084/jem.20070773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118516PMC
November 2007

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

Proc Natl Acad Sci U S A 2005 Nov 24;102(44):16066-71. Epub 2005 Oct 24.

Department of Pharmacology, Kyoto University Faculty of Medicine, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1073/pnas.0504908102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276058PMC
November 2005

Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice.

Proc Natl Acad Sci U S A 2005 Mar 7;102(11):4170-5. Epub 2005 Mar 7.

Department of Biological Sciences, Kyoto University Faculty of Medicine, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1073/pnas.0500914102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC554835PMC
March 2005

Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK).

J Biol Chem 2003 May 11;278(20):18597-605. Epub 2003 Mar 11.

Department of Pharmacology, Kyoto University Faculty of Medicine, PRESTO-Japan Science and Technology Corporation, Sakyo-ku, Kyoto 606-8315, Japan.

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http://dx.doi.org/10.1074/jbc.M300578200DOI Listing
May 2003

Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons.

J Cell Biol 2003 Apr 21;161(2):381-91. Epub 2003 Apr 21.

Dept. of Pharmacology, Kyoto University Faculty of Medicine, Yoshida, Sakyo-ku, Kyoto 606-8315, Japan.

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http://dx.doi.org/10.1083/jcb.200210149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172896PMC
April 2003

Multiple spatiotemporal modes of actin reorganization by NMDA receptors and voltage-gated Ca2+ channels.

Proc Natl Acad Sci U S A 2002 Oct 21;99(22):14458-63. Epub 2002 Oct 21.

Department of Pharmacology, Kyoto University Faculty of Medicine, Japan Science and Technology Corporation, Sakyo-ku, Kyoto 606-8315, Japan.

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http://dx.doi.org/10.1073/pnas.212148999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137905PMC
October 2002