Tomomitsu Hirota

Tomomitsu Hirota

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Tomomitsu Hirota

Publications by authors named "Tomomitsu Hirota"

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A genetic variant near TSLP is associated with chronic rhinosinusitis with nasal polyps and aspirin-exacerbated respiratory disease in Japanese populations.

Allergol Int 2019 Jul 17. Epub 2019 Jul 17.

Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan; Division of Molecular Genetics, Research Center for Medical Science, The Jikei University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2019.06.007DOI Listing
July 2019

[GENETIC FACTORS FOR THE DEVELOPMENT OF ALLERGIC DISORDERS].

Arerugi 2018;67(8):1006-1010

General Medical Laboratory, The Jikei University School of Medicine.

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https://www.jstage.jst.go.jp/article/arerugi/67/8/67_1006/_a
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http://dx.doi.org/10.15036/arerugi.67.1006DOI Listing
May 2019

How important is allergic sensitization as a cause of atopic asthma?

Allergol Int 2018 Apr 2;67(2):292-294. Epub 2017 Nov 2.

Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S13238930173015
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http://dx.doi.org/10.1016/j.alit.2017.10.005DOI Listing
April 2018

Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.

J Invest Dermatol 2018 03 12;138(3):542-548. Epub 2017 Oct 12.

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.10.001DOI Listing
March 2018

Association study of childhood food allergy with genome-wide association studies-discovered loci of atopic dermatitis and eosinophilic esophagitis.

J Allergy Clin Immunol 2017 12 16;140(6):1713-1716. Epub 2017 Jun 16.

Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan; Research Center for Medical Science, The Jikei University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.05.034DOI Listing
December 2017

Association of interleukin 1 receptor-like 1 gene polymorphisms with eosinophilic phenotype in Japanese adults with asthma.

Respir Investig 2017 Nov 22;55(6):338-347. Epub 2017 Sep 22.

Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2017.08.006DOI Listing
November 2017

[GWAS FOR ALLERGIC DISEASES].

Arerugi 2016 Feb;65(1):25-31

Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, RIKEN.

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https://www.jstage.jst.go.jp/article/arerugi/65/1/65_25/_art
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http://dx.doi.org/10.15036/arerugi.65.25DOI Listing
February 2016

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Genome-wide association study of recalcitrant atopic dermatitis in Korean children.

J Allergy Clin Immunol 2015 Sep 30;136(3):678-684.e4. Epub 2015 Apr 30.

Department of Pediatrics, Severance Hospital, Institute of Allergy, Brain Korea 21 PLUS project for Medical Science, Yonsei University College of Medicine, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.03.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562879PMC
September 2015

GENETIC FACTORS OF ALLERGIC DISEASES IN THE JAPANESE POPULATION.

Arerugi 2015 07;64(7):933-41

Laboratory for Respiratory and Allergic Diseases, Core for Genomic Medicine, Center for Integrative Medical Sciences, RIKEN.

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http://dx.doi.org/10.15036/arerugi.64.933DOI Listing
July 2015

Heritability of pulmonary function estimated from genome-wide SNPs in healthy Japanese adults.

Respir Investig 2015 Mar 14;53(2):60-7. Epub 2014 Nov 14.

Department of Pulmonology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8577, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2014.10.004DOI Listing
March 2015

Genome-Wide Association Studies of Allergic Diseases.

Allergol Int 2013 27;62(1):21-28. Epub 2015 Feb 27.

Laboratory for Respiratory Diseases, Center for Genomic Medicine, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.

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http://dx.doi.org/10.2332/allergolint.13-RAI-0539DOI Listing
February 2015

Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate.

J Dermatol Sci 2014 Oct 2;76(1):10-5. Epub 2014 Jul 2.

Laboratory of Gene Medicine, Keio University School of Medicine, Tokyo, Japan; Advanced Research Center for Genome Super Power, Keio University, Tsukuba, Ibaraki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2014.06.004DOI Listing
October 2014

[Clinical relevance of biomarkers in allergic rhinitis].

Arerugi 2014 Jun;63(6):767-74

Department of Otolaryngology Head and Neck Surgery, University of Fukui, Fukui, Japan.

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June 2014

Lung functions of Japanese patients with chronic rhinosinusitis who underwent endoscopic sinus surgery.

Allergol Int 2014 Mar 25;63(1):27-35. Epub 2013 Nov 25.

Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, The Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S132389301530005
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http://dx.doi.org/10.2332/allergolint.13-OA-0579DOI Listing
March 2014

Genome-wide association studies of atopic dermatitis.

J Dermatol 2014 Mar;41(3):213-20

Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, The Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.

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http://dx.doi.org/10.1111/1346-8138.12321DOI Listing
March 2014

[Genomic biomarker].

Arerugi 2013 May;62(5):532-9

Center for Integrative Medical Sciences, RIKEN, Japan.

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May 2013

Genome-wide association studies of allergic diseases.

Allergol Int 2013 Mar;62(1):21-8

Laboratory for Respiratory Diseases, Center for Genomic Medicine, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.

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http://dx.doi.org/10.2332/allergolint.13-RAI-0539DOI Listing
March 2013

Genomic screening for Chlamydophila pneumoniae-specific antigens using serum samples from patients with primary infection.

FEMS Microbiol Lett 2012 Apr 24;329(2):168-76. Epub 2012 Feb 24.

Department of Molecular Genetics, Kawasaki Medical School, Kurashiki, Japan.

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http://dx.doi.org/10.1111/j.1574-6968.2012.02520.xDOI Listing
April 2012

Genome-wide association studies of asthma.

Allergol Int 2011 Sep;60(3):247-52

Laboratory for Respiratory Diseases, Center for Genomic Medicine, The Institute of Physical and Chemical Research, Kanagawa, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S132389301530524
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http://dx.doi.org/10.2332/allergolint.11-RAI-0320DOI Listing
September 2011

Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes.

Int J Chron Obstruct Pulmon Dis 2011 2;6:181-9. Epub 2011 Mar 2.

Division of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.2147/COPD.S16383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064418PMC
July 2011

Replication of genetic association studies in asthma and related phenotypes.

J Hum Genet 2010 Jun 16;55(6):342-9. Epub 2010 Apr 16.

Department of Public Health, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://www.nature.com/articles/jhg201032
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http://dx.doi.org/10.1038/jhg.2010.32DOI Listing
June 2010

A functional polymorphism (-603A --> G) in the tissue factor gene promoter is associated with adult-onset asthma.

J Hum Genet 2010 Mar 12;55(3):167-74. Epub 2010 Feb 12.

First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1038/jhg.2010.4DOI Listing
March 2010

A functional polymorphism in IL-18 is associated with severity of bronchial asthma.

Am J Respir Crit Care Med 2009 Dec 10;180(11):1048-55. Epub 2009 Sep 10.

Laboratory for Respiratory Diseases, Center for Genomic Medicine, Institute of Physical and Chemical Research (RIKEN, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1164/rccm.200905-0652OCDOI Listing
December 2009

[Bronchial asthma and genes of the innate immunity].

Arerugi 2009 Jul;58(7):766-71

Laboratory for Respiratory Diseases, Center for Genomic Medicine (CGM), RIKEN.

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July 2009

Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.

Am J Respir Cell Mol Biol 2009 Mar 11;40(3):368-74. Epub 2008 Sep 11.

Laboratory for Respiratory Diseases, Center for Genomic Medicine, Institute of Physical and Chemical Research (RIKEN), 1-7-22 Suehiro, Tsurumi-ku, YokohaKanagawa 230-0045, Japan.

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http://dx.doi.org/10.1165/rcmb.2008-0041OCDOI Listing
March 2009

Large scale genotyping study for asthma in the Japanese population.

BMC Res Notes 2009 Mar 31;2:54. Epub 2009 Mar 31.

Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, 305-8577 Japan.

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http://dx.doi.org/10.1186/1756-0500-2-54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674055PMC
March 2009

Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.

Recent Pat Inflamm Allergy Drug Discov 2009 Jan;3(1):17-25

Laboratory for Respiratory Diseases, Center for Genomic Medicine, The Institute of Physical and Chemical Research (RIKEN), Yokohama, Kanagawa, Japan.

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January 2009

Association study of the C3 gene with adult and childhood asthma.

J Hum Genet 2008 20;53(8):728-38. Epub 2008 Jun 20.

Department of Public Health, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chiba, 260-8670, Japan.

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http://www.nature.com/doifinder/10.1007/s10038-008-0304-0
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http://dx.doi.org/10.1007/s10038-008-0304-0DOI Listing
October 2008

Filaggrin null mutations are associated with atopic dermatitis and elevated levels of IgE in the Japanese population: a family and case-control study.

J Hum Genet 2008 3;53(7):615-21. Epub 2008 Jun 3.

Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan.

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http://www.nature.com/doifinder/10.1007/s10038-008-0293-z
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http://dx.doi.org/10.1007/s10038-008-0293-zDOI Listing
September 2008

Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.

Am J Respir Cell Mol Biol 2007 Apr 10;36(4):491-6. Epub 2006 Nov 10.

Laboratory for Genetics of Allergic Diseases, SNP Research Center, Institute of Physical and Chemical Research (RIKEN), 1-7-22 Suehiro, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1165/rcmb.2006-0090OCDOI Listing
April 2007

An association between asthma and TNF-308G/A polymorphism: meta-analysis.

J Hum Genet 2006 25;51(8):677-85. Epub 2006 Jul 25.

Department of Pediatrics, Tsukuba Medical Center Hospital, Tsukuba, Japan.

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http://dx.doi.org/10.1007/s10038-006-0007-3DOI Listing
October 2006

A functional polymorphism in MMP-9 is associated with childhood atopic asthma.

Biochem Biophys Res Commun 2006 May;344(1):300-7

Laboratory for Genetics of Allergic Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.03.102DOI Listing
May 2006

Lack of association between the IL13 variant Arg110Gln and susceptibility to cedar pollinosis in a Japanese population.

Int Arch Allergy Immunol 2006 3;139(1):25-30. Epub 2005 Nov 3.

Department of Otorhinolaryngology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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https://www.karger.com/Article/FullText/89519
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http://dx.doi.org/10.1159/000089519DOI Listing
February 2006

Functional haplotypes of IL-12B are associated with childhood atopic asthma.

J Allergy Clin Immunol 2005 Oct 8;116(4):789-95. Epub 2005 Aug 8.

Laboratory for Genetics of Allergic Diseases, Single Nucleotide Polymorphism Research Center, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.

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http://dx.doi.org/10.1016/j.jaci.2005.06.010DOI Listing
October 2005

Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.

Hum Genet 2005 Jun 2;117(1):16-26. Epub 2005 Apr 2.

Laboratory for Genetics of Allergic Diseases, SNP Research Center, RIKEN Yokohama Institute, Institute of Physical and Chemical Research (RIKEN), Tsurumi-ku, Kanagawa, Japan.

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http://dx.doi.org/10.1007/s00439-005-1285-0DOI Listing
June 2005