Tomoko Betsuyaku

Tomoko Betsuyaku

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Tomoko Betsuyaku

Publications by authors named "Tomoko Betsuyaku"

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Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts.

J Pathol 2019 Oct 24;249(2):193-205. Epub 2019 Jun 24.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1002/path.5290DOI Listing
October 2019

Allergic bronchopulmonary aspergillosis in succession to chronic eosinophilic pneumonia.

Allergol Int 2019 Jul 19;68(3):370-371. Epub 2019 Jan 19.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.12.004DOI Listing
July 2019

Factors associated with improvements in subjective symptoms of obstructive sleep apnea syndrome after continuous positive airway pressure therapy.

Sleep Breath 2019 Jul 6. Epub 2019 Jul 6.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1007/s11325-019-01877-5DOI Listing
July 2019

Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis.

Allergy 2019 Jun 26;74(6):1113-1124. Epub 2019 Feb 26.

Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.

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http://dx.doi.org/10.1111/all.13726DOI Listing
June 2019

Drug-induced pneumonitis following the administration of laninamivir octanoate: The first two reported cases.

J Infect Chemother 2019 Jun 6. Epub 2019 Jun 6.

Kawasaki Municipal Hospital, Kanagawa, Japan.

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http://dx.doi.org/10.1016/j.jiac.2019.05.008DOI Listing
June 2019

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.

Biochem Biophys Res Commun 2019 May 6;513(2):405-411. Epub 2019 Apr 6.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X193061
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http://dx.doi.org/10.1016/j.bbrc.2019.03.211DOI Listing
May 2019

Efficacy and safety of intermittent maintenance therapy after successful treatment of Mycobacterium avium complex lung disease.

J Infect Chemother 2019 Mar 29;25(3):218-221. Epub 2018 Aug 29.

Center for Infectious Diseases and Infection Control, Keio University School of Medicine, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jiac.2018.07.021DOI Listing
March 2019

Development of lung cancer in patients with nontuberculous mycobacterial lung disease.

Respir Investig 2019 Mar 28;57(2):157-164. Epub 2018 Dec 28.

Center for Infectious Diseases and Infection Control, Keio University School of Medicine, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2018.11.004DOI Listing
March 2019

Predictive and modifying factors of bone mineral density decline in patients with COPD.

Respir Med 2019 Mar 17;148:13-23. Epub 2019 Jan 17.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1016/j.rmed.2019.01.005DOI Listing
March 2019

Calorie restriction enhances adult mouse lung stem cells function and reverses several ageing-induced changes.

J Tissue Eng Regen Med 2019 Feb 17;13(2):295-308. Epub 2019 Jan 17.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1002/term.2792DOI Listing
February 2019

Black pleural effusion caused by pancreatic pseudocyst rupture.

Clin Case Rep 2019 Feb 2;7(2):385-386. Epub 2019 Jan 2.

Division of Pulmonary Medicine, Department of Medicine Keio University School of Medicine Tokyo Japan.

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http://dx.doi.org/10.1002/ccr3.1994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389461PMC
February 2019

Fatal Airway Inflammation Induced by Pembrolizumab in a Patient With NSCLC.

J Thorac Oncol 2019 Jan;14(1):e9-e10

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jtho.2018.09.002DOI Listing
January 2019

High fat diet activates adult mouse lung stem cells and accelerates several aging-induced effects.

Stem Cell Res 2018 12 4;33:25-35. Epub 2018 Oct 4.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S18735061183024
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http://dx.doi.org/10.1016/j.scr.2018.10.006DOI Listing
December 2018

Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort.

Chron Respir Dis 2018 11 12;15(4):329-338. Epub 2017 Dec 12.

1 Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1177/1479972317745735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234576PMC
November 2018

Perfusion Defect-Concordant Progression of Unilateral Refractory Pulmonary Mycobacterium avium Complex Disease.

Am J Respir Crit Care Med 2018 09;198(6):803-804

3 Center for Infectious Diseases and Infection Control, Keio University School of Medicine, Tokyo, Japan.

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https://www.atsjournals.org/doi/10.1164/rccm.201801-0173IM
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http://dx.doi.org/10.1164/rccm.201801-0173IMDOI Listing
September 2018

The FGF2 aptamer inhibits the growth of FGF2-FGFR pathway driven lung cancer cells.

Biochem Biophys Res Commun 2018 09 11;503(3):1330-1334. Epub 2018 Jul 11.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183153
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http://dx.doi.org/10.1016/j.bbrc.2018.07.044DOI Listing
September 2018

Secondary Brain Neoplasm after Stereotactic Radiosurgery in Patients with Metastatic Non-small Cell Lung Cancer.

Intern Med 2018 Aug 9;57(16):2383-2387. Epub 2018 Mar 9.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Japan.

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http://dx.doi.org/10.2169/internalmedicine.0184-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148163PMC
August 2018

Pulmonary nocardiosis mimicking small cell lung cancer in ectopic ACTH syndrome associated with transformation of olfactory neuroblastoma: a case report.

BMC Pulm Med 2018 Aug 22;18(1):142. Epub 2018 Aug 22.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1186/s12890-018-0710-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106901PMC
August 2018

Relationship between diminution of small pulmonary vessels and emphysema in chronic obstructive pulmonary disease.

Clin Imaging 2017 Nov - Dec;46:85-90. Epub 2017 Jul 18.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.clinimag.2017.07.008DOI Listing
May 2018

Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms.

Lung Cancer 2018 05 2;119:25-35. Epub 2018 Mar 2.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.02.015DOI Listing
May 2018

Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients.

BMC Pulm Med 2018 May 2;18(1):65. Epub 2018 May 2.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1186/s12890-018-0639-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932787PMC
May 2018

Radiologic features of precancerous areas of the lungs in chronic obstructive pulmonary disease.

Int J Chron Obstruct Pulmon Dis 2017 30;12:1613-1624. Epub 2017 May 30.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo.

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http://dx.doi.org/10.2147/COPD.S132709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459962PMC
April 2018

Association between severity of obstructive sleep apnea and glycated hemoglobin level in Japanese individuals with and without diabetes.

Endocr J 2018 Jan 20;65(1):121-127. Epub 2017 Sep 20.

Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ17-0356DOI Listing
January 2018

The association between dental health and nutritional status in chronic obstructive pulmonary disease.

Chron Respir Dis 2017 Nov 6;14(4):334-341. Epub 2016 Apr 6.

3 Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1177/1479972316643076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729726PMC
November 2017

Characteristics of patients with increasing COPD assessment test scores within 3 years.

Respir Med 2017 10 14;131:101-108. Epub 2017 Aug 14.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.rmed.2017.08.012DOI Listing
October 2017

Susceptibility genes for nontuberculous mycobacterial disease.

Nihon Rinsho Meneki Gakkai Kaishi 2017 ;40(1):60-67

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine.

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http://dx.doi.org/10.2177/jsci.40.60DOI Listing
September 2017

The alpha-lipoic acid derivative DHLHZn: a new therapeutic agent for acute lung injury in vivo.

Inflamm Res 2017 Sep 1;66(9):803-811. Epub 2017 Jun 1.

Department of Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1007/s00011-017-1059-xDOI Listing
September 2017

Clinical and radiological characteristics of patients with late-onset severe restrictive lung defect after hematopoietic stem cell transplantation.

BMC Pulm Med 2017 Sep 7;17(1):123. Epub 2017 Sep 7.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1186/s12890-017-0466-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590140PMC
September 2017

Impact of mild exacerbation on COPD symptoms in a Japanese cohort.

Int J Chron Obstruct Pulmon Dis 2016 9;11:1269-78. Epub 2016 Jun 9.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.2147/COPD.S105454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907494PMC
August 2017

Subphenotypes of type 2 severe asthma in adults.

J Allergy Clin Immunol Pract 2018 Jan - Feb;6(1):274-276.e2. Epub 2017 Aug 9.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jaip.2017.06.015DOI Listing
August 2017

Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma.

Lung Cancer 2017 07 23;109:45-51. Epub 2017 Apr 23.

Division of Thoracic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2017.04.014DOI Listing
July 2017

Edoxaban treatment for pulmonary arterial thromboembolism associated with azygous vein aneurysm.

Respirol Case Rep 2017 May 26;5(3):e00223. Epub 2017 Feb 26.

Division of Pulmonary Medicine, Department of Medicine Keio University School of Medicine Tokyo Japan.

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http://dx.doi.org/10.1002/rcr2.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326810PMC
May 2017

Sternoclavicular joint osteomyelitis extending to lung abscess complicated by Staphylococcal infective endocarditis.

IDCases 2017 31;9:36-37. Epub 2017 May 31.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 160-8582, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.idcr.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479943PMC
May 2017

A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models.

Am J Physiol Lung Cell Mol Physiol 2017 02 23;312(2):L268-L276. Epub 2016 Dec 23.

Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, Global Research Cluster, Hirosawa, Wako, Saitama, Japan;

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http://dx.doi.org/10.1152/ajplung.00151.2016DOI Listing
February 2017

Overcoming EGFR Bypass Signal-Induced Acquired Resistance to ALK Tyrosine Kinase Inhibitors in ALK-Translocated Lung Cancer.

Mol Cancer Res 2017 01 5;15(1):106-114. Epub 2016 Oct 5.

Division of Pulmonary Medicine, Department of Medicine, Keio University, School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0211DOI Listing
January 2017

A Case of Non-Small Cell Lung Cancer with Possible "Disease Flare" on Nivolumab Treatment.

Case Rep Oncol Med 2016 27;2016:1075641. Epub 2016 Dec 27.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1155/2016/1075641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223009PMC
December 2016

Histone Deacetylase Inhibition Protects Mice Against Lethal Postinfluenza Pneumococcal Infection.

Crit Care Med 2016 10;44(10):e980-7

1Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.2Department of Immunology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.3Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan.4Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.5Center for Infectious Diseases and Infection Control, Keio University School of Medicine, Tokyo, Japan.6Department of Pathology, University of Michigan Medical School, Ann Arbor, MI.

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http://dx.doi.org/10.1097/CCM.0000000000001821DOI Listing
October 2016

Identification of five clusters of comorbidities in a longitudinal Japanese chronic obstructive pulmonary disease cohort.

Respir Med 2016 08 7;117:272-9. Epub 2016 Jul 7.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.rmed.2016.07.002DOI Listing
August 2016

Multiple nodular lesions following Pneumocystis pneumonia in a non-HIV immunocompromised patient.

Clin Case Rep 2016 May 1;4(5):528-30. Epub 2016 Apr 1.

Division of Pulmonary Medicine Department of Medicine Keio University School of Medicine 35 Shinanomachi Shinjuku 160-8582 Tokyo Japan.

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http://dx.doi.org/10.1002/ccr3.555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856253PMC
May 2016

[Mechanism of COPD].

Authors:
Tomoko Betsuyaku

Nihon Rinsho 2016 May;74(5):722

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May 2016

Disseminated Mycobacterium marinum Infection With a Destructive Nasal Lesion Mimicking Extranodal NK/T Cell Lymphoma: A Case Report.

Medicine (Baltimore) 2016 Mar;95(11):e3131

From the Divisions of Pulmonary Medicine (TA, MI, HN, ST, TB) and Hematology (TK, TS, SO), Department of Medicine; Division of Diagnostic Pathology (KK); and Center for Infectious Diseases and Infection Control (KS, NH), Keio University School of Medicine; Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases (NN, YH), Tokyo, Japan.

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http://pdfs.journals.lww.com/md-journal/2016/03150/Dissemina
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http://dx.doi.org/10.1097/MD.0000000000003131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839948PMC
March 2016

Mechanisms to Suppress ILC2-induced Airway Inflammation.

Ann Am Thorac Soc 2016 Mar;13 Suppl 1:S95

1 Division of Pulmonary Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1513/AnnalsATS.201508-557MGDOI Listing
March 2016

Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses.

Nat Immunol 2016 Jan 23;17(1):76-86. Epub 2015 Nov 23.

Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/ni.3309DOI Listing
January 2016

Activation of EGFR Bypass Signaling by TGFα Overexpression Induces Acquired Resistance to Alectinib in ALK-Translocated Lung Cancer Cells.

Mol Cancer Ther 2016 Jan 18;15(1):162-71. Epub 2015 Dec 18.

Division of Pulmonary Medicine, Department of Medicine, Keio University, School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0084DOI Listing
January 2016

Determinants of chronic obstructive pulmonary disease severity in the late-elderly differ from those in younger patients.

BMC Res Notes 2016 Jan 4;9. Epub 2016 Jan 4.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1186/s13104-015-1810-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700610PMC
January 2016