Publications by authors named "Tomohisa Horiguchi"

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Quantitative discrimination of biological tissues by micro-elastographic measurement using an epi-illumination Mueller matrix microscope.

Biomed Opt Express 2019 Aug 9;10(8):3847-3859. Epub 2019 Jul 9.

Graduate School of Engineering, Utsunomiya University, Utsunomiya, Tochigi, 321-8585, Japan.

We propose a method for estimating the stiffness of bio-specimens by measuring their linear retardance properties under applied stress. For this purpose, we employ an epi-illumination Mueller matrix microscope and show the procedures for its calibration. We provide experimental results demonstrating how to apply Mueller matrix data to elastography, using chicken liver and chicken heart as biological samples. Finally, we show how the histograms of linear retardance images can be used to distinguish between specimens and quantify the discrimination accuracy.
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Source
http://dx.doi.org/10.1364/BOE.10.003847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701520PMC
August 2019