Tomasz J Nowakowski

Tomasz J Nowakowski

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Tomasz J Nowakowski

Tomasz J Nowakowski

Publications by authors named "Tomasz J Nowakowski"

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30Publications

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Human brain development through the lens of cerebral organoid models.

Brain Res 2019 Dec 19;1725:146470. Epub 2019 Sep 19.

Department of Anatomy, University of California, San Francisco, CA, USA; Department of Psychiatry, University of California, San Francisco, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2019.146470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887101PMC
December 2019

A recipe book for cell types in the human brain.

Nature 2019 09;573(7772):36-37

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http://dx.doi.org/10.1038/d41586-019-02343-8DOI Listing
September 2019

Development and Arealization of the Cerebral Cortex.

Neuron 2019 Sep;103(6):980-1004

The Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research at the University of California, San Francisco, San Francisco, CA 94143, USA; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.07.009DOI Listing
September 2019

Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex.

Neuron 2019 04 12;102(1):143-158.e7. Epub 2019 Feb 12.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.01.027DOI Listing
April 2019

Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution.

Cell 2019 02;176(4):743-756.e17

Department of Neurology, University of California, San Francisco (UCSF), San Francisco, CA, USA; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544371PMC
February 2019

Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function.

Cell Rep 2019 01;26(5):1157-1173.e5

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602795PMC
January 2019

Single-cell sequencing paints diverse pictures of the brain.

Nature 2018 11;563(7729):38-39

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http://dx.doi.org/10.1038/d41586-018-07027-3DOI Listing
November 2018

Transcriptional fates of human-specific segmental duplications in brain.

Genome Res 2018 10 18;28(10):1566-1576. Epub 2018 Sep 18.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1101/gr.237610.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169893PMC
October 2018

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.

Cell 2018 07;174(3):505-520

Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247911PMC
July 2018

Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia.

Cell Stem Cell 2017 04 19;20(4):435-449.e4. Epub 2017 Jan 19.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667944PMC
April 2017

The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells.

Nat Commun 2017 01 19;8:14126. Epub 2017 Jan 19.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ncomms14126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253645PMC
January 2017

Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development.

Neuron 2016 Sep;91(6):1219-1227

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087333PMC
http://dx.doi.org/10.1016/j.neuron.2016.09.005DOI Listing
September 2016

A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA.

Neuron 2016 06 2;90(6):1174-1188. Epub 2016 Jun 2.

Neuroscience Research Institute and Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911262PMC
June 2016

Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells.

Cell Stem Cell 2016 05 30;18(5):591-6. Epub 2016 Mar 30.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860115PMC
May 2016

Single-cell analysis of long non-coding RNAs in the developing human neocortex.

Genome Biol 2016 Apr 14;17:67. Epub 2016 Apr 14.

Department of Neurological Surgery, University of California, San Francisco, Ray and Dagmar Dolby Regeneration Medicine Building, 35 Medical Center Way, RMB 1037, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1186/s13059-016-0932-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831157PMC
April 2016

Molecular identity of human outer radial glia during cortical development.

Cell 2015 Sep;163(1):55-67

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583716PMC
September 2015

Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.

Nature 2014 Nov;515(7526):264-8

Department of Neurology and The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nature13973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231536PMC
November 2014

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo.

BMC Neurosci 2012 Feb 23;13:20. Epub 2012 Feb 23.

Centre for Integrative Physiology, School of Biomedical Sciences, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1186/1471-2202-13-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347985PMC
February 2012

Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability.

BMC Neurosci 2010 Feb 24;11:26. Epub 2010 Feb 24.

Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK.

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http://bmcneurosci.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2202-11-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837049PMC
February 2010