Tomas Vaisar

Tomas Vaisar

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Tomas Vaisar

Publications by authors named "Tomas Vaisar"

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Deepening our understanding of HDL proteome.

Expert Rev Proteomics 2019 Sep 27;16(9):749-760. Epub 2019 Aug 27.

UW Medicine Diabetes Institute, Department of Medicine, University of Washington , Seattle , WA , USA.

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http://dx.doi.org/10.1080/14789450.2019.1650645DOI Listing
September 2019

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Science 2019 04;364(6436)

Northwestern University, Evanston, IL, USA.

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http://dx.doi.org/10.1126/science.aau8650DOI Listing
April 2019

Urine Complement Proteins and the Risk of Kidney Disease Progression and Mortality in Type 2 Diabetes.

Diabetes Care 2018 11 27;41(11):2361-2369. Epub 2018 Aug 27.

Division of Nephrology, Department of Internal Medicine, University of California, Davis, Davis, CA

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http://dx.doi.org/10.2337/dc18-0699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196831PMC
November 2018

Type 2 diabetes is associated with loss of HDL endothelium protective functions.

PLoS One 2018 15;13(3):e0192616. Epub 2018 Mar 15.

UW Medicine Diabetes Institute, Department of Medicine, University of Washington, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192616PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854245PMC
June 2018

Obesity and Insulin Resistance Promote Atherosclerosis through an IFNγ-Regulated Macrophage Protein Network.

Cell Rep 2018 06;23(10):3021-3030

Committee on Molecular Metabolism and Nutrition, The University of Chicago, Chicago, IL 60637, USA; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082182PMC
June 2018

Statin dose reduction with complementary diet therapy: A pilot study of personalized medicine.

Mol Metab 2018 05 20;11:137-144. Epub 2018 Feb 20.

Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Lineu Prestes, 580, B14 - 05508-900, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001350PMC
May 2018

Sex steroids mediate discrete effects on HDL cholesterol efflux capacity and particle concentration in healthy men.

J Clin Lipidol 2018 Jul - Aug;12(4):1072-1082. Epub 2018 Apr 30.

Center for Research in Reproduction and Contraception, Seattle, WA, USA; Diabetes Institute, Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.jacl.2018.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064653PMC
April 2018

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.

Mol Cell 2018 01;69(2):238-252.e7

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago 8380453, Chile; Center for Geroscience, Brain Health, and Metabolism (GERO), Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago 8380453, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.12.028DOI Listing
January 2018

Kidney function is associated with an altered protein composition of high-density lipoprotein.

Kidney Int 2017 12 26;92(6):1526-1535. Epub 2017 Jul 26.

Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA; Kidney Research Institute, University of Washington, Seattle, Washington, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696089PMC
December 2017

The Authors Reply.

Kidney Int 2017 12;92(6):1556

Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA; Kidney Research Institute, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1016/j.kint.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839142PMC
December 2017

Inflammation, remodeling, and other factors affecting HDL cholesterol efflux.

Curr Opin Lipidol 2017 02;28(1):52-59

aDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Brazil bDiabetes Institute, Department of Medicine, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/MOL.0000000000000382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567787PMC
February 2017

Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.

J Allergy Clin Immunol 2017 01 13;139(1):323-334. Epub 2016 May 13.

Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash; Department of Pediatrics, University of Washington, Seattle, Wash. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.03.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107356PMC
January 2017

Isolating and Quantifying Plasma HDL Proteins by Sequential Density Gradient Ultracentrifugation and Targeted Proteomics.

Methods Mol Biol 2016 ;1410:105-20

Department of Laboratory Medicine, University of Washington School of Medicine, Box 357110, Seattle, WA, 98195-7110, USA.

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http://dx.doi.org/10.1007/978-1-4939-3524-6_7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501989PMC
December 2016

Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration.

Circ Res 2016 06 25;119(1):83-90. Epub 2016 Apr 25.

From the Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle (J.S.M., P.M.H., G.E.R., J.W., A.D.I., C.T., B.S., T.V., J.W.H.); and Division of Cardiovascular Disease, Mayo Clinic, Rochester, MN (J.D.S., A.L.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920704PMC
June 2016

PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity.

J Lipid Res 2015 Jul 25;56(7):1351-62. Epub 2015 May 25.

Division of Medical Genetics, Department of Medicine, University of Washington School of Medicine, Seattle, WA Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA.

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http://dx.doi.org/10.1194/jlr.P058032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479339PMC
July 2015

Paraoxonase-3 is depleted from the high-density lipoproteins of autoimmune disease patients with subclinical atherosclerosis.

J Proteome Res 2015 May 13;14(5):2046-54. Epub 2015 Mar 13.

¶Kidney Research Institute, University of Washington, 325 Ninth Avenue, Seattle, Washington 98104, United States.

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http://dx.doi.org/10.1021/pr5011586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434596PMC
May 2015

Macrophage ADAM17 deficiency augments CD36-dependent apoptotic cell uptake and the linked anti-inflammatory phenotype.

Circ Res 2013 Jun 12;113(1):52-61. Epub 2013 Apr 12.

Department of Pathology, Division of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Seattle, WA 98104, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.112.30068
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http://dx.doi.org/10.1161/CIRCRESAHA.112.300683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693752PMC
June 2013

Proteomics investigations of HDL: challenges and promise.

Authors:
Tomáš Vaisar

Curr Vasc Pharmacol 2012 Jul;10(4):410-21

Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, 815 Mercer St, Seattle, WA 98109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685576PMC
July 2012

Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity.

J Lipid Res 2012 Jul 13;53(7):1376-83. Epub 2012 Apr 13.

Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1194/jlr.P026005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371249PMC
July 2012

Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).

J Biol Chem 2011 Sep 2;286(38):33335-44. Epub 2011 Aug 2.

Departments of Medicine, Pathology and Cell Biology, and Physiology, and Cellular Biophysics, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M111.263020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190938PMC
September 2011

Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation.

Biochemistry 2010 Aug;49(34):7314-22

Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98109, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi100359f
Publisher Site
http://dx.doi.org/10.1021/bi100359fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930196PMC
August 2010

HDL in humans with cardiovascular disease exhibits a proteomic signature.

Clin Chim Acta 2010 Jul 20;411(13-14):972-9. Epub 2010 Mar 20.

Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1016/j.cca.2010.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862883PMC
July 2010

A macrophage sterol-responsive network linked to atherogenesis.

Cell Metab 2010 Feb;11(2):125-35

Department of Medicine, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.cmet.2010.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893224PMC
February 2010

HDL lipids and insulin resistance.

Curr Diab Rep 2010 Feb;10(1):78-86

Department of Laboratory Medicine, University of Washington School of Medicine, Mailstop 358055, 815 Mercer Street, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1007/s11892-009-0085-7DOI Listing
February 2010

Mapping the lung proteome in cystic fibrosis.

J Proteome Res 2009 Jun;8(6):3020-8

Center for Lung Biology and, Department of Medicine, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1021/pr900093jDOI Listing
June 2009

MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages.

Mol Cell Proteomics 2009 May 30;8(5):1044-60. Epub 2008 Dec 30.

Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1074/mcp.M800449-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689762PMC
May 2009

Thematic review series: proteomics. Proteomic analysis of lipid-protein complexes.

Authors:
Tomas Vaisar

J Lipid Res 2009 May 19;50(5):781-6. Epub 2009 Feb 19.

Department of Medicine, University of Washington, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1194/jlr.R900005-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666164PMC
May 2009

Spectral index for assessment of differential protein expression in shotgun proteomics.

J Proteome Res 2008 Mar 17;7(3):845-54. Epub 2008 Jan 17.

Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1021/pr070271+DOI Listing
March 2008

Myeloperoxidase and inflammatory proteins: pathways for generating dysfunctional high-density lipoprotein in humans.

Curr Atheroscler Rep 2007 Nov;9(5):417-24

Department of Medicine, HSB-BB512, Box 356426, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.

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November 2007

In situ enrichment of phosphopeptides on MALDI plates functionalized by reactive landing of zirconium(IV)-n-propoxide ions.

Anal Chem 2007 Jul 15;79(14):5449-56. Epub 2007 Jun 15.

Departments of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195-1700, USA.

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http://dx.doi.org/10.1021/ac070790wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576294PMC
July 2007

Pathways for oxidation of high-density lipoprotein in human cardiovascular disease.

Curr Opin Mol Ther 2006 Jun;8(3):198-205

Department of Medicine, University of Washington, Seattle, WA 98195, USA.

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June 2006

Copper-mediated intra-ligand oxygen transfer in gas-phase complexes with 3-nitrotyrosine.

J Mass Spectrom 2005 May;40(5):608-14

Department of Medicine, University of Washington, Seattle, 98195-1700, USA.

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http://dx.doi.org/10.1002/jms.829DOI Listing
May 2005

Sulphonamide-based small molecule VLA-4 antagonists.

Bioorg Med Chem Lett 2003 Nov;13(21):3875-8

Molecumetics, 2023 120th Avenue N E., Bellevue, WA 98005, USA.

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http://dx.doi.org/10.1016/s0960-894x(03)00760-1DOI Listing
November 2003