Tomas R Guilarte

Tomas R Guilarte

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Tomas R Guilarte

Publications by authors named "Tomas R Guilarte"

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PET imaging of dopamine release in the frontal cortex of manganese-exposed non-human primates.

J Neurochem 2019 Jul 26;150(2):188-201. Epub 2019 Mar 26.

Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jnc.14681
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http://dx.doi.org/10.1111/jnc.14681DOI Listing
July 2019

TSPO in diverse CNS pathologies and psychiatric disease: A critical review and a way forward.

Pharmacol Ther 2019 Feb 4;194:44-58. Epub 2018 Sep 4.

Robert Stempel College of Public Health & Social Work, Environmental Health Sciences, Cognitive Neuroscience & Imaging Florida International University, 11200 SW 8(th) St, AHC5-507, Miami, FL 33199, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348013PMC
February 2019

Residential Lead-Hazard Interventions, Childhood Anxiety, and Cognitive Impairment.

JAMA Pediatr 2019 Feb;173(2):198-199

Robert Stempel College of Public Health and Social Work, Florida International University, Miami.

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http://dx.doi.org/10.1001/jamapediatrics.2018.4710DOI Listing
February 2019

Letter to the Editor: Regarding Foster et al., Neonatal C57BL/6J and parkin mice respond differently following developmental manganese exposure: Result of a high dose pilot study.

Neurotoxicology 2018 12 21;69:187. Epub 2017 Nov 21.

Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL, 33199, United States; Department of Environmental Health Sciences, Florida International University, Miami, FL, 33199, United States; Cognitive Neuroscience & Imaging, Florida International University, Miami, FL, 33199, United States; Brain Behavior & Environment-FIU Emerging Pre-Eminent Program, Florida International University, Miami, FL, 33199, United States; Biomolecular Sciences Institute, Florida International University, Miami, FL, 33199, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2017.11.005DOI Listing
December 2018

From the Cover: 7,8-Dihydroxyflavone Rescues Lead-Induced Impairment of Vesicular Release: A Novel Therapeutic Approach for Lead Intoxicated Children.

Toxicol Sci 2018 01;161(1):186-195

Department of Environmental & Occupational Health, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, Florida 33199.

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http://dx.doi.org/10.1093/toxsci/kfx210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837521PMC
January 2018

Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children.

Environ Health Perspect 2017 04 26;125(4):721-729. Epub 2016 Aug 26.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1289/EHP265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381979PMC
April 2017

Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain.

Toxicology 2016 Dec 16;374:1-9. Epub 2016 Nov 16.

Dept. of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA; Dept. of Neuroscience, University of Parma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154914PMC
December 2016

Chronic early life lead (Pb) exposure alters presynaptic vesicle pools in hippocampal synapses.

BMC Pharmacol Toxicol 2016 11 2;17(1):56. Epub 2016 Nov 2.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.

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http://dx.doi.org/10.1186/s40360-016-0098-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090882PMC
November 2016

Neurochemistry of lead and manganese.

Metallomics 2016 06;8(6):561-2

Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA.

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http://dx.doi.org/10.1039/c6mt90017hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467876PMC
June 2016

TSPO Finds NOX2 in Microglia for Redox Homeostasis.

Trends Pharmacol Sci 2016 May 21;37(5):334-343. Epub 2016 Apr 21.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1016/j.tips.2016.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042807PMC
May 2016

Presynaptic mechanisms of lead neurotoxicity: effects on vesicular release, vesicle clustering and mitochondria number.

PLoS One 2015 26;10(5):e0127461. Epub 2015 May 26.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127461PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444102PMC
April 2016

TSPO in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiology.

Neurobiol Dis 2016 Jan 3;85:174-186. Epub 2015 Nov 3.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961153008
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http://dx.doi.org/10.1016/j.nbd.2015.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688219PMC
January 2016

Biomarker and more: can translocator protein 18 kDa predict recovery from brain injury and myocarditis?

Biomark Med 2014 ;8(5):605-7

Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.2217/bmm.14.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378562PMC
August 2015

Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence.

Toxicol Sci 2015 Aug;146(2):204-12

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032.

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http://dx.doi.org/10.1093/toxsci/kfv099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607750PMC
August 2015

BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity.

J Neurochem 2014 Dec 2;131(5):655-66. Epub 2014 Sep 2.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1111/jnc.12926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296578PMC
December 2014

Chronic exposure of mutant DISC1 mice to lead produces sex-dependent abnormalities consistent with schizophrenia and related mental disorders: a gene-environment interaction study.

Schizophr Bull 2014 May 28;40(3):575-84. Epub 2013 May 28.

*To whom correspondence should be addressed; Department of Environmental Health Sciences, Columbia University, Mailman School of Public Health, 722 West 168th Street, Room 1105-E, New York, NY 10032, US; tel: 212-305-3959, fax: 212-305-3857, e-mail:

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http://dx.doi.org/10.1093/schbul/sbt071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984515PMC
May 2014

Manganese neurotoxicity: new perspectives from behavioral, neuroimaging, and neuropathological studies in humans and non-human primates.

Front Aging Neurosci 2013 24;5:23. Epub 2013 Jun 24.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University New York, NY, USA.

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http://dx.doi.org/10.3389/fnagi.2013.00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690350PMC
June 2013

Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primates.

Toxicol Lett 2013 Mar 20;217(3):177-83. Epub 2012 Dec 20.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.toxlet.2012.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638947PMC
March 2013

Mechanisms of lead and manganese neurotoxicity.

Toxicol Res (Camb) 2013 Mar;2(2):99-114

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1039/C2TX20064CDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338437PMC
March 2013

Pathophysiology of manganese-associated neurotoxicity.

Neurotoxicology 2012 Aug 21;33(4):881-6. Epub 2011 Dec 21.

Department of Neurology, Washington University School of Medicine, St. Louis, MO 63131, USA.

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http://dx.doi.org/10.1016/j.neuro.2011.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350837PMC
August 2012

Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses.

Neurotoxicology 2012 Jun 9;33(3):560-74. Epub 2011 Dec 9.

Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY 10032, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S0161813X1100208
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http://dx.doi.org/10.1016/j.neuro.2011.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647679PMC
June 2012

Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for an environmental basis of neurodevelopmental disorders.

Toxicol Sci 2012 May 17;127(1):277-95. Epub 2012 Feb 17.

Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York City, New York 10031, USA.

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http://dx.doi.org/10.1093/toxsci/kfs090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327871PMC
May 2012

Manganese and Parkinson's disease: a critical review and new findings.

Cien Saude Colet 2011 Nov;16(11):4549-66

Neurotoxicology and Molecular Imaging Laboratory, Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1590/s1413-81232011001200028DOI Listing
November 2011

Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates.

Neurotoxicology 2011 Mar 26;32(2):215-26. Epub 2010 Nov 26.

Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0161813X1000221
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http://dx.doi.org/10.1016/j.neuro.2010.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057349PMC
March 2011

Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibition.

Neurotoxicology 2011 Mar 28;32(2):281-9. Epub 2010 Dec 28.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neuro.2010.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049857PMC
March 2011

Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state.

Glia 2011 Feb;59(2):219-30

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/glia.21091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425360PMC
February 2011

The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice.

Biol Sex Differ 2011 Feb 21;2. Epub 2011 Feb 21.

Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1186/2042-6410-2-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049118PMC
February 2011

Molecular neurobiology of lead (Pb(2+)): effects on synaptic function.

Mol Neurobiol 2010 Dec 2;42(3):151-60. Epub 2010 Nov 2.

Department of Pharmacology and Toxicology, Michigan State University, B307 Life Sciences Building, East Lansing, MI 48824, USA.

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http://dx.doi.org/10.1007/s12035-010-8146-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076195PMC
December 2010

APLP1, Alzheimer's-like pathology and neurodegeneration in the frontal cortex of manganese-exposed non-human primates.

Neurotoxicology 2010 Sep 25;31(5):572-4. Epub 2010 Feb 25.

Neurotoxicology & Molecular Imaging Laboratory, Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, 615 N. Wolfe St. Rm E6622, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neuro.2010.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902550PMC
September 2010

Manganese and Parkinson's disease: a critical review and new findings.

Environ Health Perspect 2010 Aug 19;118(8):1071-80. Epub 2010 Apr 19.

Neurotoxicology and Molecular Imaging Laboratory, Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1289/ehp.0901748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920085PMC
August 2010

Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potential role of NMDA receptor-dependent BDNF signaling.

Toxicol Sci 2010 Jul 7;116(1):249-63. Epub 2010 Apr 7.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1093/toxsci/kfq111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886862PMC
July 2010

Silica-based nanoparticle uptake and cellular response by primary microglia.

Environ Health Perspect 2010 May;118(5):589-95

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1289/ehp.0901534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866671PMC
May 2010

Synthesis of [(125)I]iodoDPA-713: a new probe for imaging inflammation.

Biochem Biophys Res Commun 2009 Nov 22;389(1):80-3. Epub 2009 Aug 22.

Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/j.bbrc.2009.08.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764231PMC
November 2009

Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain.

Toxicol Sci 2009 Sep 10;111(1):131-9. Epub 2009 Jun 10.

Department of Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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https://academic.oup.com/toxsci/article/1670510/Effects
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http://dx.doi.org/10.1093/toxsci/kfp124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726295PMC
September 2009

Manganese neurotoxicity: lessons learned from longitudinal studies in nonhuman primates.

Environ Health Perspect 2009 Mar 3;117(3):325-32. Epub 2008 Oct 3.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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https://ehp.niehs.nih.gov/doi/10.1289/ehp.0800035
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http://dx.doi.org/10.1289/ehp.0800035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661898PMC
March 2009

Developmental lead exposure impairs extinction of conditioned fear in young adult rats.

Neurotoxicology 2008 Nov 10;29(6):1127-30. Epub 2008 Jul 10.

Neurotoxicology & Molecular Imaging Laboratory, Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.neuro.2008.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628441PMC
November 2008

Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates.

J Neurochem 2008 Jun 13;105(5):1948-59. Epub 2008 Feb 13.

Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://doi.wiley.com/10.1111/j.1471-4159.2008.05295.x
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http://dx.doi.org/10.1111/j.1471-4159.2008.05295.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335763PMC
June 2008

VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.

J Neurochem 2008 Apr 5;105(1):78-90. Epub 2007 Nov 5.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.05108.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137401PMC
April 2008

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair.

Pharmacol Ther 2008 Apr 9;118(1):1-17. Epub 2008 Feb 9.

Neurotoxicology & Molecular Imaging Laboratory, Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2007.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453598PMC
April 2008

Dysregulation of glutamate carboxypeptidase II in psychiatric disease.

Schizophr Res 2008 Feb 10;99(1-3):324-32. Epub 2008 Jan 10.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.schres.2007.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287371PMC
February 2008

Manganese inhibits NMDA receptor channel function: implications to psychiatric and cognitive effects.

Neurotoxicology 2007 Nov 26;28(6):1147-52. Epub 2007 Jun 26.

Neurotoxicology & Molecular Imaging Laboratory, Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21205, United States.

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http://dx.doi.org/10.1016/j.neuro.2007.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100416PMC
November 2007

Manganese: recent advances in understanding its transport and neurotoxicity.

Toxicol Appl Pharmacol 2007 Jun 12;221(2):131-47. Epub 2007 Mar 12.

Department of Pediatrics, and The Kennedy Center for Research on Human Development, Vanderbilt University, School of Medicine, Nashville, TN 37232-2495, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0041008X0700106
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http://dx.doi.org/10.1016/j.taap.2007.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950780PMC
June 2007

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

Mol Cancer Ther 2007 Jan;6(1):154-62

Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Room E7541, 615 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0516DOI Listing
January 2007

Nigrostriatal dopamine system dysfunction and subtle motor deficits in manganese-exposed non-human primates.

Exp Neurol 2006 Dec 22;202(2):381-90. Epub 2006 Aug 22.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.expneurol.2006.06.015DOI Listing
December 2006

In vivo modulation of the Parkinsonian phenotype by Nrf2.

Neurotoxicology 2006 Dec 5;27(6):1094-100. Epub 2006 Aug 5.

Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neuro.2006.07.019DOI Listing
December 2006

Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI study.

Toxicol Sci 2006 Dec 12;94(2):351-8. Epub 2006 Sep 12.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1093/toxsci/kfl106DOI Listing
December 2006

An extended simplified reference tissue model for the quantification of dynamic PET with amphetamine challenge.

Neuroimage 2006 Nov 21;33(2):550-63. Epub 2006 Aug 21.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N. Caroline St., JHOC room 3245, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2006.06.038DOI Listing
November 2006

Effects of chronic manganese exposure on cognitive and motor functioning in non-human primates.

Brain Res 2006 Nov 15;1118(1):222-31. Epub 2006 Sep 15.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, 521 JAH, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.08.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892239PMC
November 2006

Experience-dependent regulation of zif268 gene expression and spatial learning.

Exp Neurol 2006 Jul 20;200(1):209-15. Epub 2006 Mar 20.

Molecular Neurotoxicology Laboratory, Division of Toxicological Sciences, Department of Environmental Health Sciences, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001448860600064
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http://dx.doi.org/10.1016/j.expneurol.2006.02.006DOI Listing
July 2006

Imaging the peripheral benzodiazepine receptor response in central nervous system demyelination and remyelination.

Toxicol Sci 2006 Jun 22;91(2):532-9. Epub 2006 Mar 22.

Molecular Neurotoxicology Laboratory, Department of Environmental Health Sciences, The Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1093/toxsci/kfj172DOI Listing
June 2006

Acute manganese administration alters dopamine transporter levels in the non-human primate striatum.

Neurotoxicology 2006 Mar 2;27(2):229-36. Epub 2005 Dec 2.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neuro.2005.10.008DOI Listing
March 2006

In vivo imaging of peripheral benzodiazepine receptors in mouse lungs: a biomarker of inflammation.

Mol Imaging 2005 Oct-Dec;4(4):432-8

Loyola College, Baltimore, MD, USA.

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January 2006

Lead neurotoxicity: from exposure to molecular effects.

Brain Res Brain Res Rev 2005 Nov 31;49(3):529-54. Epub 2005 Mar 31.

Department of Environmental Health Sciences, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.brainresrev.2005.02.004DOI Listing
November 2005

Glutamate carboxypeptidase II levels in rodent brain using [125I]DCIT quantitative autoradiography.

Neurosci Lett 2005 Oct;387(3):141-4

Department of Environmental Health Sciences, Johns Hopkins School of Public Health, Baltimore, MD 21287-2182, USA.

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http://dx.doi.org/10.1016/j.neulet.2005.06.015DOI Listing
October 2005

Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS.

J Neurovirol 2005 Aug;11(4):346-55

Department of Radiology, the Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-2182, USA.

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http://dx.doi.org/10.1080/13550280500187351DOI Listing
August 2005

Calcium/calmodulin-dependent protein kinase II activity and expression are altered in the hippocampus of Pb2+-exposed rats.

Brain Res 2005 May 2;1044(1):51-8. Epub 2005 Apr 2.

Division of Toxicological Sciences, Department of Environmental Health Sciences, The Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.brainres.2005.02.076DOI Listing
May 2005

Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization.

Brain 2004 Jun 6;127(Pt 6):1379-92. Epub 2004 Apr 6.

Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Room W2001, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1093/brain/awh161DOI Listing
June 2004

Lead exposure alters cyclic-AMP response element binding protein phosphorylation and binding activity in the developing rat brain.

Brain Res Dev Brain Res 2003 Nov;145(2):219-28

Department of Environmental Health Sciences, The Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Room W2001, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.devbrainres.2003.08.004DOI Listing
November 2003

Selective decrease in NR1 subunit splice variant mRNA in the hippocampus of Pb2+-exposed rats: implications for synaptic targeting and cell surface expression of NMDAR complexes.

Brain Res Mol Brain Res 2003 May;113(1-2):37-43

Molecular Neurotoxicology Laboratory, Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/s0169-328x(03)00083-4DOI Listing
May 2003

Elevated peripheral benzodiazepine receptor expression in simian immunodeficiency virus encephalitis.

J Neurovirol 2003 Feb;9(1):94-100

Department of Comparative Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1080/13550280390173283DOI Listing
February 2003

Environmental enrichment reverses cognitive and molecular deficits induced by developmental lead exposure.

Ann Neurol 2003 Jan;53(1):50-6

Department of Environmental Health Sciences, The Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1002/ana.10399DOI Listing
January 2003

Developmental Pb2+ exposure alters NMDAR subtypes and reduces CREB phosphorylation in the rat brain.

Brain Res Dev Brain Res 2002 Dec;139(2):217-26

Department of Environmental Health Sciences, The Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Room W2001, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/s0165-3806(02)00569-2DOI Listing
December 2002