Tomas Ganz

Tomas Ganz

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Tomas Ganz

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Effects of maternal iron status on placental and fetal iron homeostasis.

J Clin Invest 2019 Dec 17. Epub 2019 Dec 17.

Center for Iron Disorders, Department of Medicine and.

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http://dx.doi.org/10.1172/JCI127341DOI Listing
December 2019

Elevated Fibroblast Growth Factor 23 Levels Are Associated With Greater Diastolic Dysfunction in ESRD.

Kidney Int Rep 2019 Dec 9;4(12):1748-1751. Epub 2019 Aug 9.

Veterans Affairs, Greater Los Angeles Healthcare System, Los Angeles, California, USA.

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http://dx.doi.org/10.1016/j.ekir.2019.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895593PMC
December 2019

Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell?

Am J Nephrol 2018 13;47(2):72-83. Epub 2018 Feb 13.

Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1159/000486968DOI Listing
October 2019

The Discovery of the Iron-Regulatory Hormone Hepcidin.

Authors:
Tomas Ganz

Clin Chem 2019 Oct 24;65(10):1330-1331. Epub 2019 Jun 24.

Departments of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

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http://dx.doi.org/10.1373/clinchem.2019.306407DOI Listing
October 2019

New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia.

Haematologica 2019 Sep 21;104(9):1768-1781. Epub 2019 Feb 21.

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China

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http://dx.doi.org/10.3324/haematol.2018.209874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717595PMC
September 2019

Iron Metabolism in Chronic Kidney Disease Patients.

Contrib Nephrol 2019 16;198:103-111. Epub 2019 Apr 16.

Division of Nephrology, Department of Medicine, Showa University, School of Medicine, Tokyo, Japan.

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https://www.karger.com/Article/FullText/496369
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http://dx.doi.org/10.1159/000496369DOI Listing
September 2019

Anemia of Inflammation.

Authors:
Tomas Ganz

N Engl J Med 2019 Sep;381(12):1148-1157

From the Departments of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles.

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http://dx.doi.org/10.1056/NEJMra1804281DOI Listing
September 2019

Novel Oral Iron Therapies for Iron Deficiency Anemia in Chronic Kidney Disease.

Adv Chronic Kidney Dis 2019 07;26(4):272-291

David Geffen School of Medicine, UCLA, Los Angeles, CA.

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https://linkinghub.elsevier.com/retrieve/pii/S15485595193011
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http://dx.doi.org/10.1053/j.ackd.2019.05.002DOI Listing
July 2019

Mechanism of Action and Clinical Attributes of Auryxia (Ferric Citrate).

Drugs 2019 Jun;79(9):957-968

David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

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http://link.springer.com/10.1007/s40265-019-01125-w
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http://dx.doi.org/10.1007/s40265-019-01125-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562046PMC
June 2019

William Ganz and His Legacy.

Ann Intern Med 2019 05;170(10):734-735

University of California, San Francisco, San Francisco, California (P.G.).

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http://dx.doi.org/10.7326/L19-0033DOI Listing
May 2019

Erythropoietic regulators of iron metabolism.

Authors:
Tomas Ganz

Free Radic Biol Med 2019 03 5;133:69-74. Epub 2018 Jul 5.

Departments of Medicine and Pathology, David Geffen School of Medicine, UCLA, Los Angeles, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320727PMC
March 2019

Iron homeostasis in pregnancy and spontaneous abortion.

Am J Hematol 2019 02 26;94(2):184-188. Epub 2018 Nov 26.

Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California.

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http://doi.wiley.com/10.1002/ajh.25341
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http://dx.doi.org/10.1002/ajh.25341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687303PMC
February 2019

Increased gene copy number of worsens sepsis by inducing endothelial pyroptosis.

Proc Natl Acad Sci U S A 2019 02 4;116(8):3161-3170. Epub 2019 Feb 4.

Department of Clinical Research Center, Children's Hospital, Zhejiang University School of Medicine, 310052 Hangzhou, China;

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http://dx.doi.org/10.1073/pnas.1812947116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386704PMC
February 2019

Anemia of inflammation.

Blood 2019 01 6;133(1):40-50. Epub 2018 Nov 6.

Department of Pathology and.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-06
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http://dx.doi.org/10.1182/blood-2018-06-856500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536698PMC
January 2019

Erythropoietin and iron-a conflicted alliance?

Authors:
Tomas Ganz

Kidney Int 2018 11;94(5):851-853

Departments of Medicine and Pathology, UCLA School of Medicine, Los Angeles, California, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00852538183062
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http://dx.doi.org/10.1016/j.kint.2018.07.027DOI Listing
November 2018

Erythrocytes and erythroblasts give up iron.

Authors:
Tomas Ganz

Blood 2018 11;132(19):2004-2005

University of California, Los Angeles.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-09
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http://dx.doi.org/10.1182/blood-2018-09-876102DOI Listing
November 2018

Evaluation of serum markers for improved detection of autologous blood transfusions.

Haematologica 2018 10 19;103(10):e443-e445. Epub 2018 Apr 19.

Sports Medicine Research and Testing Laboratory, Salt Lake City, UT, USA.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.190918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165801PMC
October 2018

Dysregulated iron metabolism in polycythemia vera: etiology and consequences.

Leukemia 2018 10 24;32(10):2105-2116. Epub 2018 Jul 24.

Division of Hematology Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41375-018-0207-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170398PMC
October 2018

Comment on "Serum Hepcidin and Soluble Transferrin Receptor in the Assessment of Iron Metabolism in Children on a Vegetarian Diet".

Biol Trace Elem Res 2018 09 10;185(1):252-254. Epub 2018 Jan 10.

Departments of Medicine and Pathology, David Geffen School of Medicine, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1007/s12011-018-1241-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097060PMC
September 2018

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice.

Physiol Rep 2018 09;6(19):e13890

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California.

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http://doi.wiley.com/10.14814/phy2.13890
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http://dx.doi.org/10.14814/phy2.13890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185995PMC
September 2018

Calcium is an essential cofactor for metal efflux by the ferroportin transporter family.

Nat Commun 2018 08 6;9(1):3075. Epub 2018 Aug 6.

Structural Biology Program, Centenary Institute, Sydney Medical School, University of Sydney, Sydney, NSW, 2042, Australia.

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http://dx.doi.org/10.1038/s41467-018-05446-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079014PMC
August 2018

Iron storage disease (hemochromatosis) and hepcidin response to iron load in two species of pteropodid fruit bats relative to the common vampire bat.

J Comp Physiol B 2018 07 29;188(4):683-694. Epub 2018 Mar 29.

Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road, Guelph, ON, N1G 2W1, Canada.

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http://dx.doi.org/10.1007/s00360-018-1155-4DOI Listing
July 2018

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients.

Infect Immun 2018 07 21;86(7). Epub 2018 Jun 21.

Department of Pediatric Critical Care, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

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http://dx.doi.org/10.1128/IAI.00253-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013672PMC
July 2018

Erythroferrone: An Erythroid Regulator of Hepcidin and Iron Metabolism.

Hemasphere 2018 Mar-Apr;2(2):e35. Epub 2018 Mar 28.

Departments of Medicine and Pathology, University of California Los Angeles, CA.

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http://dx.doi.org/10.1097/HS9.0000000000000035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745900PMC
March 2018

Iron and infection.

Authors:
Tomas Ganz

Int J Hematol 2018 Jan 16;107(1):7-15. Epub 2017 Nov 16.

CHS 52-243, Departments of Medicine and Pathology, David Geffen School of Medicine, University of California, 10833 Le Conte Ave., Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/s12185-017-2366-2DOI Listing
January 2018

Correction to: Iron and infection.

Authors:
Tomas Ganz

Int J Hematol 2018 01;107(1):122

CHS 52-243, Departments of Medicine and Pathology, David Geffen School of Medicine, University of California, 10833 Le Conte Ave., Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/s12185-017-2385-zDOI Listing
January 2018

Iron-related markers are associated with infection after liver transplantation.

Liver Transpl 2017 12;23(12):1541-1552

Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA.

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http://dx.doi.org/10.1002/lt.24817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696081PMC
December 2017

mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice.

Am J Physiol Gastrointest Liver Physiol 2017 Nov 10;313(5):G511-G523. Epub 2017 Aug 10.

Department of Nutritional Science & Toxicology, University of California, Berkeley, California.

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http://dx.doi.org/10.1152/ajpgi.00307.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792216PMC
November 2017

In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively than Iron and Erythropoietin Treatment.

Shock 2017 10;48(4):490-497

*Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California†Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, California.

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http://dx.doi.org/10.1097/SHK.0000000000000886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603371PMC
October 2017

Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.

J Hepatol 2017 08 22;67(2):360-369. Epub 2017 Mar 22.

Department of Pathology (Division of Experimental Pathology), University of Pittsburgh, Pennsylvania, United States; Pittsburgh Liver Research Center, University of Pittsburgh, Pennsylvania, United States; Department of Medicine (Division of Gastroenterology, Hepatology and Nutrition), University of Pittsburgh, Pennsylvania, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515705PMC
August 2017

Iron homeostasis: An anthropocentric perspective.

J Biol Chem 2017 08 14;292(31):12727-12734. Epub 2017 Jun 14.

From the Departments of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-1690

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http://dx.doi.org/10.1074/jbc.R117.781823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546013PMC
August 2017

Does Pathological Iron Overload Impair the Function of Human Lungs?

Authors:
Tomas Ganz

EBioMedicine 2017 06 17;20:13-14. Epub 2017 May 17.

Center for Iron Disorders, Departments of Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478249PMC
June 2017

Erythroferrone and matriptase-2 independently regulate hepcidin expression.

Am J Hematol 2017 05 24;92(5):E61-E63. Epub 2017 Feb 24.

IRSD, Université de Toulouse, INSERM U1220, INRA U1416, ENVT, UPS, Toulouse, France.

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http://dx.doi.org/10.1002/ajh.24672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389904PMC
May 2017

Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model.

Haematologica 2017 03 24;102(3):e85-e88. Epub 2016 Nov 24.

Department of Pediatrics, A.I. duPont Hospital for Children, Wilmington, DE, USA.

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http://dx.doi.org/10.3324/haematol.2016.150433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394962PMC
March 2017

Hepcidin.

Authors:
Tomas Ganz

Rinsho Ketsueki 2016;57(10):1913-1917

Department of Medicine and Pathology, David Geffen School of Medicine, University of California.

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http://dx.doi.org/10.11406/rinketsu.57.1913DOI Listing
February 2017

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia.

Haematologica 2017 01 22;102(1):60-68. Epub 2016 Sep 22.

IRSD, Université de Toulouse, INSERM U1220, INRA U1416, ENVT, UPS, Toulouse, France

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http://dx.doi.org/10.3324/haematol.2016.150227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210233PMC
January 2017

Macrophages and Iron Metabolism.

Authors:
Tomas Ganz

Microbiol Spectr 2016 10;4(5)

Departments of Medicine and Pathology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.

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http://dx.doi.org/10.1128/microbiolspec.MCHD-0037-2016DOI Listing
October 2016

Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera.

Blood 2016 07 6;128(2):265-76. Epub 2016 May 6.

Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; Division of Hematology-Oncology, Department of Pediatrics, Weill Cornell Medical College, New York, NY; Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY; and Cell and Molecular Biology Graduate Group, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/blood-2015-10-676742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946204PMC
July 2016

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics.

Biochim Biophys Acta 2016 Apr 2;1863(4):727-48. Epub 2016 Feb 2.

Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, The University of Sydney, Sydney, NSW, 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2016.01.026DOI Listing
April 2016

Iron Balance and the Role of Hepcidin in Chronic Kidney Disease.

Semin Nephrol 2016 03;36(2):87-93

Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1016/j.semnephrol.2016.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884601PMC
March 2016

Isocitrate treatment of acute anemia of inflammation in a mouse model.

Blood Cells Mol Dis 2016 Jan 28;56(1):31-6. Epub 2015 Sep 28.

Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660302PMC
January 2016

Small cyclic agonists of iron regulatory hormone hepcidin.

Bioorg Med Chem Lett 2015 Nov 12;25(21):4961-4969. Epub 2015 Mar 12.

Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90095, USA; The Pasarow Mass Spectrometry Laboratory, The Jane and Terry Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567957PMC
November 2015

Ironing out Ferroportin.

Cell Metab 2015 Nov 1;22(5):777-87. Epub 2015 Oct 1.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635047PMC
November 2015

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

Blood 2015 Oct 14;126(17):2031-7. Epub 2015 Aug 14.

Department of Medicine and Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA; and.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-07-65
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http://dx.doi.org/10.1182/blood-2015-07-658419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616236PMC
October 2015

Iron homeostasis in host defence and inflammation.

Nat Rev Immunol 2015 Aug 10;15(8):500-10. Epub 2015 Jul 10.

Department of Medicine, David Geffen School of Medicine at University of California.

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http://dx.doi.org/10.1038/nri3863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801113PMC
August 2015

Hepcidin and Host Defense against Infectious Diseases.

PLoS Pathog 2015 Aug 20;11(8):e1004998. Epub 2015 Aug 20.

Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America; The Carter Center for Immunology, University of Virginia, Charlottesville, Virginia, United States of America; Department of Internal Medicine, University of Virginia, Charlottesville, Virginia, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546197PMC
August 2015

Mouse models of anemia of cancer.

PLoS One 2014 28;9(3):e93283. Epub 2014 Mar 28.

Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America; Department of Pathology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093283PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969362PMC
June 2015

Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver.

Exp Hematol 2015 Jun 14;43(6):469-78.e6. Epub 2015 Mar 14.

Division of Hematology, Department of Medicine, University of Washington, Seattle, Washington, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771411PMC
June 2015

Hepcidin and the global burden of iron deficiency.

Authors:
Tomas Ganz

Clin Chem 2015 Apr 9;61(4):577-8. Epub 2014 Dec 9.

Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1373/clinchem.2014.229179DOI Listing
April 2015

Thiol-derivatized minihepcidins retain biological activity.

Bioorg Med Chem Lett 2015 Feb 6;25(4):763-6. Epub 2015 Jan 6.

Department of Medicine, University of California at Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.12.094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318710PMC
February 2015

Disordered hepcidin-ferroportin signaling promotes breast cancer growth.

Cell Signal 2014 Nov 3;26(11):2539-50. Epub 2014 Aug 3.

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.07.029DOI Listing
November 2014

Erythroferrone contributes to recovery from anemia of inflammation.

Blood 2014 Oct 5;124(16):2569-74. Epub 2014 Sep 5.

Department of Medicine and Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

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http://www.bloodjournal.org/content/early/2014/09/05/blood-2
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-06-58
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http://dx.doi.org/10.1182/blood-2014-06-584607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199959PMC
October 2014

Anemia of inflammation.

Hematol Oncol Clin North Am 2014 Aug 28;28(4):671-81, vi. Epub 2014 May 28.

Department of Medicine, David Geffen School of Medicine at UCLA, 37-055 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Pathology, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2014.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115203PMC
August 2014

Identification of erythroferrone as an erythroid regulator of iron metabolism.

Nat Genet 2014 Jul 1;46(7):678-84. Epub 2014 Jun 1.

1] Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA. [2] Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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http://www.nature.com/articles/ng.2996
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http://dx.doi.org/10.1038/ng.2996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104984PMC
July 2014

Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc.

Am J Physiol Cell Physiol 2014 Mar 4;306(5):C450-9. Epub 2013 Dec 4.

Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio;

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http://www.physiology.org/doi/10.1152/ajpcell.00348.2013
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http://dx.doi.org/10.1152/ajpcell.00348.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042619PMC
March 2014

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.

Hepatology 2014 Feb 16;59(2):683-94. Epub 2013 Dec 16.

Inserm, U1043, Toulouse, France; CNRS, U5282, Toulouse, France; Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, France.

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http://dx.doi.org/10.1002/hep.26648DOI Listing
February 2014

Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6.

Infect Immun 2014 Feb 2;82(2):745-52. Epub 2013 Dec 2.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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http://dx.doi.org/10.1128/IAI.00983-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911381PMC
February 2014

Cellular catabolism of the iron-regulatory peptide hormone hepcidin.

PLoS One 2013 11;8(3):e58934. Epub 2013 Mar 11.

Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058934PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594189PMC
December 2013

Preface: iron and cancer.

Authors:
Tomas Ganz

Crit Rev Oncog 2013 ;18(5):preceding 391

Departments of Medicine and Pathology David Geffen School of Medicine, UCLA, Los Angeles, CA.

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http://dx.doi.org/10.1615/critrevoncog.2013007770DOI Listing
December 2013

Testing the iron hypothesis in a mouse model of atherosclerosis.

Cell Rep 2013 Dec 5;5(5):1436-42. Epub 2013 Dec 5.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880128PMC
December 2013

Systemic iron homeostasis.

Authors:
Tomas Ganz

Physiol Rev 2013 Oct;93(4):1721-41

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http://www.physiology.org/doi/10.1152/physrev.00008.2013
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http://dx.doi.org/10.1152/physrev.00008.2013DOI Listing
October 2013

Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin.

Biopolymers 2013 Sep;100(5):519-26

Institute for Molecular Bioscience, The University of Queensland, Institute for Molecular Bioscience, Brisbane QLD, 4072, Australia.

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http://dx.doi.org/10.1002/bip.22350DOI Listing
September 2013

High-throughput screening of small molecules identifies hepcidin antagonists.

Mol Pharmacol 2013 Mar 4;83(3):681-90. Epub 2013 Jan 4.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1124/mol.112.083428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583499PMC
March 2013

Macrophages and systemic iron homeostasis.

Authors:
Tomas Ganz

J Innate Immun 2012 21;4(5-6):446-53. Epub 2012 Mar 21.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1159/000336423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741611PMC
January 2013

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis.

Blood 2012 Nov 18;120(18):3829-36. Epub 2012 Sep 18.

Department of Chemistry and Biochemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1690, USA.

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http://dx.doi.org/10.1182/blood-2012-07-440743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488893PMC
November 2012

Hepcidin and iron homeostasis.

Biochim Biophys Acta 2012 Sep 26;1823(9):1434-43. Epub 2012 Jan 26.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2012.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048856PMC
September 2012

Iron homeostasis and its disorders in mice and men: potential lessons for rhinos.

J Zoo Wildl Med 2012 Sep;43(3 Suppl):S19-26

Departments of Medicine, David Geffen School of Medicine, 10833 Le Conte Avenue, Los Angeles, California 90095-1690. USA.

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http://www.bioone.org/doi/abs/10.1638/2011-0158.1
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September 2012

IOD in rhinos--immunity group report: report from the Immunity, Genetics and Toxicology Working Group of the International Workshop on Iron Overload Disorder in Browsing Rhinoceros (February 2011).

J Zoo Wildl Med 2012 Sep;43(3 Suppl):S117-9

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1638/1042-7260-43.3s.S117DOI Listing
September 2012

Inhibition of hepcidin transcription by growth factors.

Hepatology 2012 Jul 18;56(1):291-9. Epub 2012 Jun 18.

Department of Pathology, University of California, Los Angeles, CA 90095-1690, USA.

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http://doi.wiley.com/10.1002/hep.25615
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http://dx.doi.org/10.1002/hep.25615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362690PMC
July 2012

Iron metabolism: interactions with normal and disordered erythropoiesis.

Cold Spring Harb Perspect Med 2012 May;2(5):a011668

Department of Medicine and Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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http://dx.doi.org/10.1101/cshperspect.a011668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331689PMC
May 2012

The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders.

Hematology Am Soc Hematol Educ Program 2011 ;2011:538-42

Department of Pulmonary & Critical Care Medicine, University of California-Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1182/asheducation-2011.1.538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034574PMC
April 2012

Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome.

Liver Int 2011 Aug 18;31(7):994-1000. Epub 2011 Apr 18.

Department of Clinical Medicine and Prevention, Centre for Diagnosis and Therapy of Hemochromatosis, S. Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1111/j.1478-3231.2011.02520.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048852PMC
August 2011