Publications by authors named "Tom van der Poll"

100Publications

Transcriptional changes in alveolar macrophages from adults with asthma after allergen challenge.

Allergy 2020 Dec 23. Epub 2020 Dec 23.

Center of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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December 2020

Alkaline phosphatase in pulmonary inflammation-a translational study in ventilated critically ill patients and rats.

Intensive Care Med Exp 2020 Dec 18;8(Suppl 1):46. Epub 2020 Dec 18.

Department of Intensive Care, Amsterdam University Medical Centers, location "VU", Mail stop ZH 7D-172, De Boelelaan 1117, 1082 RW, Amsterdam, the Netherlands.

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December 2020

The predictive validity for mortality of the driving pressure and the mechanical power of ventilation.

Intensive Care Med Exp 2020 Dec 18;8(Suppl 1):60. Epub 2020 Dec 18.

Department of Intensive Care, University of Amsterdam, Amsterdam University Medical Centers, Location "Academic Medical Center", Meibergdreeg 9, 1105 AZ, Amsterdam, The Netherlands.

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December 2020

Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia.

Front Immunol 2020 27;11:626667. Epub 2020 Nov 27.

Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, Netherlands.

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November 2020

The leukocyte non-coding RNA landscape in critically ill patients with sepsis.

Elife 2020 12 11;9. Epub 2020 Dec 11.

Amsterdam UMC, University of Amsterdam, Center for Experimental Molecular Medicine, Amsterdam Infection & Immunity, Amsterdam, Netherlands.

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December 2020

Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation.

PLoS One 2020 4;15(11):e0241748. Epub 2020 Nov 4.

Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands.

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December 2020

What Sepsis Researchers Can Learn from COVID-19.

Am J Respir Crit Care Med 2021 01;203(1):125-127

Amsterdam UMC, location Academic Medical Center Amsterdam, the Netherlands.

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January 2021

A Higher Fluid Balance in the Days After Septic Shock Reversal Is Associated With Increased Mortality: An Observational Cohort Study.

Crit Care Explor 2020 Oct 23;2(10):e0219. Epub 2020 Sep 23.

Department of Intensive Care Medicine, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.

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October 2020

Bronchial Epithelial Tet2 Maintains Epithelial Integrity during Acute Pseudomonas aeruginosa Pneumonia.

Infect Immun 2020 Dec 15;89(1). Epub 2020 Dec 15.

Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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December 2020

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Authors:
Derek C Angus Lennie Derde Farah Al-Beidh Djillali Annane Yaseen Arabi Abigail Beane Wilma van Bentum-Puijk Lindsay Berry Zahra Bhimani Marc Bonten Charlotte Bradbury Frank Brunkhorst Meredith Buxton Adrian Buzgau Allen C Cheng Menno de Jong Michelle Detry Lise Estcourt Mark Fitzgerald Herman Goossens Cameron Green Rashan Haniffa Alisa M Higgins Christopher Horvat Sebastiaan J Hullegie Peter Kruger Francois Lamontagne Patrick R Lawler Kelsey Linstrum Edward Litton Elizabeth Lorenzi John Marshall Daniel McAuley Anna McGlothin Shay McGuinness Bryan McVerry Stephanie Montgomery Paul Mouncey Srinivas Murthy Alistair Nichol Rachael Parke Jane Parker Kathryn Rowan Ashish Sanil Marlene Santos Christina Saunders Christopher Seymour Anne Turner Frank van de Veerdonk Balasubramanian Venkatesh Ryan Zarychanski Scott Berry Roger J Lewis Colin McArthur Steven A Webb Anthony C Gordon Farah Al-Beidh Derek Angus Djillali Annane Yaseen Arabi Wilma van Bentum-Puijk Scott Berry Abigail Beane Zahra Bhimani Marc Bonten Charlotte Bradbury Frank Brunkhorst Meredith Buxton Allen Cheng Menno De Jong Lennie Derde Lise Estcourt Herman Goossens Anthony Gordon Cameron Green Rashan Haniffa Francois Lamontagne Patrick Lawler Edward Litton John Marshall Colin McArthur Daniel McAuley Shay McGuinness Bryan McVerry Stephanie Montgomery Paul Mouncey Srinivas Murthy Alistair Nichol Rachael Parke Kathryn Rowan Christopher Seymour Anne Turner Frank van de Veerdonk Steve Webb Ryan Zarychanski Lewis Campbell Andrew Forbes David Gattas Stephane Heritier Lisa Higgins Peter Kruger Sandra Peake Jeffrey Presneill Ian Seppelt Tony Trapani Paul Young Sean Bagshaw Nick Daneman Niall Ferguson Cheryl Misak Marlene Santos Sebastiaan Hullegie Mathias Pletz Gernot Rohde Kathy Rowan Brian Alexander Kim Basile Timothy Girard Christopher Horvat David Huang Kelsey Linstrum Jennifer Vates Richard Beasley Robert Fowler Steve McGloughlin Susan Morpeth David Paterson Bala Venkatesh Tim Uyeki Kenneth Baillie Eamon Duffy Rob Fowler Thomas Hills Katrina Orr Asad Patanwala Steve Tong Mihai Netea Shilesh Bihari Marc Carrier Dean Fergusson Ewan Goligher Ghady Haidar Beverley Hunt Anand Kumar Mike Laffan Patrick Lawless Sylvain Lother Peter McCallum Saskia Middeldopr Zoe McQuilten Matthew Neal John Pasi Roger Schutgens Simon Stanworth Alexis Turgeon Alexandra Weissman Neill Adhikari Matthew Anstey Emily Brant Angelique de Man Francois Lamonagne Marie-Helene Masse Andrew Udy Donald Arnold Phillipe Begin Richard Charlewood Michael Chasse Mark Coyne Jamie Cooper James Daly Iain Gosbell Heli Harvala-Simmonds Tom Hills Sheila MacLennan David Menon John McDyer Nicole Pridee David Roberts Manu Shankar-Hari Helen Thomas Alan Tinmouth Darrell Triulzi Tim Walsh Erica Wood Carolyn Calfee Cecilia O’Kane Murali Shyamsundar Pratik Sinha Taylor Thompson Ian Young Shailesh Bihari Carol Hodgson John Laffey Danny McAuley Neil Orford Ary Neto Michelle Detry Mark Fitzgerald Roger Lewis Anna McGlothlin Ashish Sanil Christina Saunders Lindsay Berry Elizabeth Lorenzi Eliza Miller Vanessa Singh Claire Zammit Wilma van Bentum Puijk Wietske Bouwman Yara Mangindaan Lorraine Parker Svenja Peters Ilse Rietveld Kik Raymakers Radhika Ganpat Nicole Brillinger Rene Markgraf Kate Ainscough Kathy Brickell Aisha Anjum Janis-Best Lane Alvin Richards-Belle Michelle Saull Daisy Wiley Julian Bion Jason Connor Simon Gates Victoria Manax Tom van der Poll John Reynolds Marloes van Beurden Evelien Effelaar Joost Schotsman Craig Boyd Cain Harland Audrey Shearer Jess Wren Giles Clermont William Garrard Kyle Kalchthaler Andrew King Daniel Ricketts Salim Malakoutis Oscar Marroquin Edvin Music Kevin Quinn Heidi Cate Karen Pearson Joanne Collins Jane Hanson Penny Williams Shane Jackson Adeeba Asghar Sarah Dyas Mihaela Sutu Sheenagh Murphy Dawn Williamson Nhlanhla Mguni Alison Potter David Porter Jayne Goodwin Clare Rook Susie Harrison Hannah Williams Hilary Campbell Kaatje Lomme James Williamson Jonathan Sheffield Willian van’t Hoff Phobe McCracken Meredith Young Jasmin Board Emma Mart Cameron Knott Julie Smith Catherine Boschert Julia Affleck Mahesh Ramanan Ramsy D’Souza Kelsey Pateman Arif Shakih Winston Cheung Mark Kol Helen Wong Asim Shah Atul Wagh Joanne Simpson Graeme Duke Peter Chan Brittney Cartner Stephanie Hunter Russell Laver Tapaswi Shrestha Adrian Regli Annamaria Pellicano James McCullough Mandy Tallott Nikhil Kumar Rakshit Panwar Gail Brinkerhoff Cassandra Koppen Federica Cazzola Matthew Brain Sarah Mineall Roy Fischer Vishwanath Biradar Natalie Soar Hayden White Kristen Estensen Lynette Morrison Joanne Smith Melanie Cooper Monash Health Yahya Shehabi Wisam Al-Bassam Amanda Hulley Christina Whitehead Julie Lowrey Rebecca Gresha James Walsham Jason Meyer Meg Harward Ellen Venz Patricia Williams Catherine Kurenda Kirsy Smith Margaret Smith Rebecca Garcia Deborah Barge Deborah Byrne Kathleen Byrne Alana Driscoll Louise Fortune Pierre Janin Elizabeth Yarad Naomi Hammond Frances Bass Angela Ashelford Sharon Waterson Steve Wedd Robert McNamara Heidi Buhr Jennifer Coles Sacha Schweikert Bradley Wibrow Rashmi Rauniyar Erina Myers Ed Fysh Ashlish Dawda Bhaumik Mevavala Ed Litton Janet Ferrier Priya Nair Hergen Buscher Claire Reynolds John Santamaria Leanne Barbazza Jennifer Homes Roger Smith Lauren Murray Jane Brailsford Loretta Forbes Teena Maguire Vasanth Mariappa Judith Smith Scott Simpson Matthew Maiden Allsion Bone Michelle Horton Tania Salerno Martin Sterba Wenli Geng Pieter Depuydt Jan De Waele Liesbet De Bus Jan Fierens Stephanie Bracke Brenda Reeve William Dechert Michaël Chassé François Martin Carrier Dounia Boumahni Fatna Benettaib Ali Ghamraoui David Bellemare Ève Cloutier Charles Francoeur François Lamontagne Frédérick D’Aragon Elaine Carbonneau Julie Leblond Gloria Vazquez-Grande Nicole Marten Maggie Wilson Martin Albert Karim Serri Alexandros Cavayas Mathilde Duplaix Virginie Williams Bram Rochwerg Tim Karachi Simon Oczkowski John Centofanti Tina Millen Erick Duan 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Siobhan Casey Maeve Kernan Peter Doran Michael O’Dywer Michelle Smyth Leanne Hayes Oscar Hoiting Marco Peters Els Rengers Mirjam Evers Anton Prinssen Jeroen Bosch Ziekenhuis Koen Simons Wim Rozendaal F Polderman P de Jager M Moviat A Paling A Salet Emma Rademaker Anna Linda Peters E de Jonge J Wigbers E Guilder M Butler Keri-Anne Cowdrey Lynette Newby Yan Chen Catherine Simmonds Rachael McConnochie Jay Ritzema Carter Seton Henderson Kym Van Der Heyden Jan Mehrtens Tony Williams Alex Kazemi Rima Song Vivian Lai Dinu Girijadevi Robert Everitt Robert Russell Danielle Hacking Ulrike Buehner Erin Williams Troy Browne Kate Grimwade Jennifer Goodson Owen Keet Owen Callender Robert Martynoga Kara Trask Amelia Butler Livia Schischka Chelsea Young Eden Lesona Shaanti Olatunji Yvonne Robertson Nuno José Teodoro Amaro dos Santos Catorze Tiago Nuno Alfaro de Lima Pereira Lucilia Maria Neves Pessoa Ricardo Manuel Castro Ferreira Joana Margarida Pereira Sousa Bastos Simin Aysel Florescu Delia Stanciu 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JAMA 2020 10;324(13):1317-1329

Division of Anaesthetics, Pain Medicine and Intensive Care Medicine, Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom.

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October 2020

Norepinephrine in Septic Shock: A Mixed Blessing.

Am J Respir Crit Care Med 2020 09;202(6):788-789

Amsterdam University Medical Centers University of Amsterdam Amsterdam, the Netherlands.

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September 2020

The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis.

Crit Care 2020 07 13;24(1):423. Epub 2020 Jul 13.

Center for Experimental Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Room G2-105, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.

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July 2020

Myeloid Liver Kinase B1 depletion is associated with a reduction in alveolar macrophage numbers and an impaired host defense during gram-negative pneumonia.

J Infect Dis 2020 Jul 10. Epub 2020 Jul 10.

Center for Experimental and Molecular Medicine Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

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July 2020

Elevated trefoil factor 3 plasma levels in critically ill patients with abdominal sepsis or non-infectious abdominal illness.

Cytokine 2020 Sep 27;133:155181. Epub 2020 Jun 27.

Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; The Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Division of Infectious Diseases, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.

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September 2020

Immunomodulation by macrolides: therapeutic potential for critical care.

Lancet Respir Med 2020 06;8(6):619-630

Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, Netherlands; Division of Infectious Diseases, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, Netherlands. Electronic address:

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June 2020

Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study.

Intensive Care Med 2020 Aug 8;46(8):1576-1589. Epub 2020 Jun 8.

Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Room G2-130; Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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August 2020

Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia.

Front Immunol 2020 6;11:796. Epub 2020 May 6.

Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, Netherlands.

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May 2020

SIRP-α instructs alveolar macrophages to stop eating after pneumonia.

Nat Immunol 2020 06;21(6):601-603

Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.

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June 2020

Caspase-11 contributes to pulmonary host defense against and local activation of coagulation.

Am J Physiol Lung Cell Mol Physiol 2020 07 13;319(1):L105-L114. Epub 2020 May 13.

Center of Experimental and Molecular Medicine, Amsterdam, The Netherlands.

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July 2020

Investigational treatment of rheumatoid arthritis with a vibrotactile device applied to the external ear.

Bioelectron Med 2019 17;5. Epub 2019 Apr 17.

1Center for Biomedical Science and Bioelectronic Medicine, Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY USA.

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April 2019

Platelet Activation and Endothelial Cell Dysfunction.

Crit Care Clin 2020 Apr 5;36(2):233-253. Epub 2020 Feb 5.

Department of Pediatrics, Pediatric Hematology/Oncology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794-8111, USA. Electronic address:

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April 2020

Correction to: Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study.

Crit Care 2020 02 6;24(1):41. Epub 2020 Feb 6.

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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February 2020

Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study.

Crit Care 2019 12 12;23(1):408. Epub 2019 Dec 12.

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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December 2019

Tenascin C Plasma Levels in Critically Ill Patients with or Without Sepsis: A Multicenter Observational Study.

Shock 2020 07;54(1):62-69

Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Academic Medical Center, University of Amsterdam.

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July 2020

Current gaps in sepsis immunology: new opportunities for translational research.

Lancet Infect Dis 2019 12 17;19(12):e422-e436. Epub 2019 Oct 17.

Hospital Universitario Río Hortega, Valladolid, Spain; Group for Biomedical Research in Sepsis, Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain; Centro de Investigación Biomedica En Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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December 2019

Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice.

J Pathol 2020 01 25;250(1):95-106. Epub 2019 Nov 25.

Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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January 2020

Robustness of sepsis-3 criteria in critically ill patients.

J Intensive Care 2019 29;7:46. Epub 2019 Aug 29.

8Department of Medical Microbiology and Immunology, Rijnstate Hospital, Arnhem, the Netherlands.

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August 2019

Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation.

J Thromb Haemost 2019 11 13;17(11):1989-1994. Epub 2019 Aug 13.

University College London Hospitals NHS Foundation Trust, London, UK.

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November 2019

C3a signaling is not involved in eosinophil migration during experimental allergic lung inflammation in mice.

Allergy 2020 04 3;75(4):934-936. Epub 2019 Sep 3.

Center of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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April 2020

Genetic signature related to heme-hemoglobin metabolism pathway in sepsis secondary to pneumonia.

NPJ Syst Biol Appl 2019 1;5:26. Epub 2019 Aug 1.

1Division of Infectious Diseases, Department of Medicine, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, São Paulo, Brazil.

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April 2020

An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic.

Clin Infect Dis 2019 08;69(Suppl 1):S40-S47

Paratek Pharmaceuticals, Inc., King of Prussia, Pennsylvania.

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August 2019

Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemia.

J Leukoc Biol 2019 11 7;106(5):1153-1160. Epub 2019 Jul 7.

Center for Experimental Molecular Medicine, Amsterdam University Medical Centers, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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November 2019

Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis.

Eur J Clin Microbiol Infect Dis 2019 Oct 26;38(10):1829-1836. Epub 2019 Jun 26.

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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October 2019

Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?

Crit Care 2019 06 20;23(1):226. Epub 2019 Jun 20.

Center of Infection and Immunity Amsterdam (CINIMA), Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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June 2019

Role of Toll-Like Receptor 5 (TLR5) in Experimental Melioidosis.

Infect Immun 2019 08 23;87(8). Epub 2019 Jul 23.

Center for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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August 2019

Recombinant Human Soluble Thrombomodulin in Patients With Sepsis-Associated Coagulopathy: Another Negative Sepsis Trial?

Authors:
Tom van der Poll

JAMA 2019 05;321(20):1978-1980

Center of Experimental and Molecular Medicine, Division of Infectious Diseases, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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May 2019

Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis.

Intensive Care Med Exp 2019 Mar 12;7(1):14. Epub 2019 Mar 12.

Center of Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-130, 1105 AZ, Amsterdam, the Netherlands.

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March 2019

Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis.

Thromb Haemost 2019 Jun 14;119(6):930-940. Epub 2019 Mar 14.

Center for Experimental and Molecular Medicine (CEMM), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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June 2019

Initiation of renal replacement therapy in patients with sepsis: more to it than meets the eye.

Ann Transl Med 2018 Dec;6(Suppl 2):S130

Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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December 2018

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia.

Mol Med 2019 01 15;25(1). Epub 2019 Jan 15.

Center for Experimental and Molecular Medicine (CEMM), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-132, 1105, AZ, Amsterdam, the Netherlands.

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January 2019

Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study.

Crit Care 2018 12 18;22(1):348. Epub 2018 Dec 18.

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, P.O. Box 85500, 3508 GA, Utrecht, the Netherlands.

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December 2018

Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis.

J Innate Immun 2019 17;11(2):168-180. Epub 2018 Dec 17.

Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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May 2020

Correction to: What's new in immunostimulating strategies in the ICU.

Intensive Care Med 2019 01;45(1):137

Division of Infectious Diseases and Center of Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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January 2019

Neutrophils mitigate the systemic host response during endotoxemia in mice.

Immunology 2019 03 18;156(3):277-281. Epub 2018 Dec 18.

Center of Experimental & Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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March 2019

What's new in immunostimulating strategies in the ICU.

Intensive Care Med 2019 01 19;45(1):110-112. Epub 2018 Nov 19.

Division of Infectious Diseases and Center of Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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January 2019

Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model.

Am J Physiol Lung Cell Mol Physiol 2019 01 25;316(1):L187-L196. Epub 2018 Oct 25.

Center of Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam , Amsterdam , The Netherlands.

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January 2019

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.

Cell Metab 2019 01 4;29(1):211-220.e5. Epub 2018 Oct 4.

Department of Internal Medicine (463) and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen 6500 HB, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany; Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, Craiova, Romania.

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January 2019

Inhibition of the extrinsic or intrinsic coagulation pathway during pneumonia-derived sepsis.

Am J Physiol Lung Cell Mol Physiol 2018 11 23;315(5):L799-L809. Epub 2018 Aug 23.

Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam , Amsterdam , The Netherlands.

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November 2018

MRP8/14 does not contribute to dissemination or inflammation in a murine model of Lyme borreliosis.

Immunobiology 2018 11 17;223(11):694-698. Epub 2018 Jul 17.

Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands; Division of Infectious Diseases, Academic Medical Center, Amsterdam, The Netherlands.

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November 2018

Microglial Activation After Systemic Stimulation With Lipopolysaccharide and .

Front Cell Neurosci 2018 24;12:110. Epub 2018 Apr 24.

Department of Neurology, Center of Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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April 2018

Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis.

Eur J Clin Microbiol Infect Dis 2018 Jul 26;37(7):1333-1344. Epub 2018 Apr 26.

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Room F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

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July 2018

Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis.

Platelets 2019 12;30(3):296-304. Epub 2018 Mar 12.

a Center for Experimental and Molecular Medicine, Academic Medical Center , University of Amsterdam , Amsterdam , The Netherlands.

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April 2019

Myocardial Injury in Patients With Sepsis and Its Association With Long-Term Outcome.

Circ Cardiovasc Qual Outcomes 2018 02;11(2):e004040

From the Department of Epidemiology, Julius Center for Health Sciences and Primary Care (J.F.F., C.S., M.E.K.-B., M.J.M.B.), Department of Intensive Care Medicine (J.F.F., D.W.D., M.E.K.-B., I.W.S., D.S.Y.O., O.L.C.), Department of Medical Microbiology (D.S.Y.O., M.J.M.B.), and Department of Anesthesiology (W.A.v.K.), University Medical Center Utrecht, The Netherlands; Department of Mathematics, Utrecht University, The Netherlands (C.S.); Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands (J.H.); and Center for Experimental and Molecular Medicine (T.v.d.P.) and Division of Infectious Diseases (T.v.d.P.), Academic Medical Center, Amsterdam, The Netherlands.

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February 2018

The host response in critically ill sepsis patients on statin therapy: a prospective observational study.

Ann Intensive Care 2018 Jan 18;8(1). Epub 2018 Jan 18.

Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-130, 1105 AZ, Amsterdam, The Netherlands.

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January 2018

Are histones real pathogenic agents in sepsis?

Nat Rev Immunol 2018 02 27;18(2):148. Epub 2017 Dec 27.

Department of Internal Medicine, and the Center for Infectious Diseases, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, Netherlands.

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February 2018

Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria.

Blood 2018 02 29;131(8):864-876. Epub 2017 Nov 29.

Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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February 2018

Biomarkers in Sepsis.

Crit Care Clin 2018 Jan 12;34(1):139-152. Epub 2017 Oct 12.

Division of Laboratory Specialties, Center for Experimental Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-130, Amsterdam 1105AZ, The Netherlands; Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-130, Amsterdam 1105AZ, The Netherlands.

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January 2018

Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis.

Am J Physiol Lung Cell Mol Physiol 2018 03 9;314(3):L397-L405. Epub 2017 Nov 9.

Center of Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam , Amsterdam , The Netherlands.

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March 2018

Neutrophil extracellular traps in patients with pulmonary tuberculosis.

Respir Res 2017 10 30;18(1):181. Epub 2017 Oct 30.

Centre for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-130, 1105, AZ, Amsterdam, The Netherlands.

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October 2017

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study.

Lancet Respir Med 2017 10 29;5(10):816-826. Epub 2017 Aug 29.

Center for Experimental Molecular Medicine, Academic Medical Center, Amsterdam, Netherlands; Division of Infectious Diseases, Academic Medical Center, Amsterdam, Netherlands.

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October 2017

Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients.

Crit Care Med 2017 11;45(11):1854-1862

1Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 2The Center for Infection and Immunity, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 3Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, Amsterdam, the Netherlands. 4Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, the Netherlands. 5Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands. 6Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. 7Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 8Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany. 9Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany. 10Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. 11Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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November 2017

Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching.

Crit Care Med 2017 Nov;45(11):1871-1879

1School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. 2Victorian Infectious Diseases Service, The Doherty Institute, Melbourne, Victoria, Australia. 3Australian Institute of Tropical Medicine and Hygiene, James Cook University, Douglas, Queensland, Australia. 4Pharmaceutical Care Department, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia. 5Intensive Care Department, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia. 6Regional Intensive Care Unit, Royal Victoria Hospital, Belfast, Northern Ireland. 7Multidisciplinary Epidemiology and Translational Research in Intensive Care, Mayo Clinic, Rochester, MN. 8Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN. 9Division of Pulmonary and Critical Medicine, Chiayi Christian Hospital, Chiayi, Taiwan. 10Department of Nephrology, Taipei City Hospital Heping Fuyou Branch, Taipei, Taiwan, Republic of China. 11Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, Rome, Italy. 12Division of Critical Care Medicine, Department of Medicine, Montefiore Medical Center, Bronx, NY. 13Department of Medicine, Albert Einstein College of Medicine, Bronx, NY. 14Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY. 15Department of Anesthesiology, Division of Critical Care Medicine, Mayo Clinic, Rochester, MN. 16Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany. 17Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland. 18Louisiana State University Health Sciences Center, Department of Medicine, Section of Pulmonary and Critical Care Medicine, Baton Rouge, LA. 19Division of Infectious Diseases and Hospital Epidemiology, Department of Medicine and Clinical Research, University Hospital Basel, Basel, Switzerland. 20Clinic for Anaesthesiology and Intensive Care Medicine, University Hospital Jena, Jena, Germany. 21Department of Internal Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China. 22Department of Internal Medicine, Division of Critical Care Medicine, San Rafael Hospital, Alajuela, Costa Rica. 23Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. 24Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. 25Department of Internal Medicine and Medical Specialties, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. 26Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN. 27The Center for Infection and Immunity, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. 28College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia. 29Infectious Diseases Unit, The Townsville Hospital, Douglas, Queensland, Australia.

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November 2017

Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi.

Infection 2017 Dec 7;45(6):893-896. Epub 2017 Aug 7.

Division of Infectious Diseases, Center of Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Room G2-105, 1105 AZ, Amsterdam, The Netherlands.

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December 2017

Myeloid-derived Suppressor Cells in Sepsis.

Authors:
Tom van der Poll

Am J Respir Crit Care Med 2017 08;196(3):256-258

1 Academic Medical Center University of Amsterdam Amsterdam, the Netherlands.

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August 2017

Expression of intra- and extracellular granzymes in patients with typhoid fever.

PLoS Negl Trop Dis 2017 Jul 27;11(7):e0005823. Epub 2017 Jul 27.

Department of Internal Medicine, Division of Infectious Diseases and Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, the Netherlands.

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July 2017

Diabetes Is Not Associated With Increased 90-Day Mortality Risk in Critically Ill Patients With Sepsis.

Crit Care Med 2017 Oct;45(10):e1026-e1035

1Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 2Center for Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 3Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 4NICE foundation, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. 5Department of Intensive Care Medicine, Leiden University Medical Center, Leiden, the Netherlands. 6Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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October 2017