Tom W J Huizinga

Tom W J Huizinga

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Tom W J Huizinga

Tom W J Huizinga

Publications by authors named "Tom W J Huizinga"

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Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening.

J Rheumatol 2019 Jul 1. Epub 2019 Jul 1.

From the Department of Rheumatology, Department of Cardiology, Department of Pulmonology, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Dr. N.M. van Leeuwen, Department of Rheumatology, Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail:

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http://dx.doi.org/10.3899/jrheum.181378DOI Listing
July 2019

Treat-to-Target Strategies in Rheumatoid Arthritis.

JAMA 2019 07;322(1):83

Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1001/jama.2019.5848DOI Listing
July 2019

Sex hormones and sex hormone-targeting therapies in systemic sclerosis: A systematic literature review.

Semin Arthritis Rheum 2019 Jul 20. Epub 2019 Jul 20.

Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2019.07.007DOI Listing
July 2019

N-linked glycans in the variable domain of ACPA-IgG predict the development of rheumatoid arthritis.

Arthritis Rheumatol 2019 May 8. Epub 2019 May 8.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/art.40920DOI Listing
May 2019

Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria.

Rheumatology (Oxford) 2019 Apr;58(4):730-732

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kez005DOI Listing
April 2019

Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study.

J Rheumatol 2019 Apr 1;46(4):405-415. Epub 2019 Mar 1.

From the Department of Cardiology, Heart Lung Center, and the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.171207DOI Listing
April 2019

Depression and anxiety associate with less remission after 1 year in rheumatoid arthritis.

Ann Rheum Dis 2019 Jan 8;78(1):e1. Epub 2018 Jan 8.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2017-212867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314454PMC
January 2019

To what extent do autoantibodies help to identify high-risk patients in systemic sclerosis?

Clin Exp Rheumatol 2018 Jul-Aug;36 Suppl 113(4):109-117. Epub 2018 Jul 18.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

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January 2019

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

Cancer Immunol Res 2019 Jan 13;7(1):6-11. Epub 2018 Nov 13.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

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http://cancerimmunolres.aacrjournals.org/lookup/doi/10.1158/
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http://dx.doi.org/10.1158/2326-6066.CIR-18-0245DOI Listing
January 2019

On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis.

Rheumatol Int 2018 12 20;38(12):2225-2231. Epub 2018 Oct 20.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://link.springer.com/10.1007/s00296-018-4173-3
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http://dx.doi.org/10.1007/s00296-018-4173-3DOI Listing
December 2018

An evidence-based approach to pre-pregnancy counselling for patients with systemic lupus erythematosus.

Rheumatology (Oxford) 2018 10;57(10):1707-1720

Department of Gynaecology and Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kex374DOI Listing
October 2018

MR signal intensity: staying on the bright side in MR image interpretation.

RMD Open 2018 20;4(1):e000728. Epub 2018 Jun 20.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/rmdopen-2018-000728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018882PMC
June 2018

The B cell response to citrullinated antigens in the development of rheumatoid arthritis.

Nat Rev Rheumatol 2018 03 8;14(3):157-169. Epub 2018 Feb 8.

Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands.

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http://www.nature.com/doifinder/10.1038/nrrheum.2018.10
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http://dx.doi.org/10.1038/nrrheum.2018.10DOI Listing
March 2018

Is optimising gout treatment the key to closing the mortality gap in gout patients?

Ann Rheum Dis 2018 01 25;77(1):e2. Epub 2017 May 25.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2017-211638DOI Listing
January 2018

Preventing progression from arthralgia to arthritis: targeting the right patients.

Nat Rev Rheumatol 2018 Jan 9;14(1):32-41. Epub 2017 Nov 9.

Department of Rheumatology, Leiden University Medical Centre, C4-R, PO Box 9600, Leiden, RC 2300, The Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2017.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298577PMC
January 2018

Dosing down with biologic therapies: a systematic review and clinicians' perspective.

Rheumatology (Oxford) 2017 11;56(11):1847-1856

Department of Rheumatology, Leiden University Medical Center, Leiden, C1-41, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kew464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850865PMC
November 2017

Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort.

J Rheumatol 2017 Nov 15;44(11):1659-1666. Epub 2017 Sep 15.

From the departments of Rheumatology, Radiology, and Clinical Epidemiology, Leiden University Medical Center (LUMC), Leiden, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.170208DOI Listing
November 2017

Rheumatoid arthritis patients with continued low disease activity have similar outcomes over 10 years, regardless of initial therapy.

Rheumatology (Oxford) 2017 10;56(10):1721-1728

Department of Rheumatology, Leiden University Medical Center, Leiden.

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http://dx.doi.org/10.1093/rheumatology/kex236DOI Listing
October 2017

Auto-antibodies and cancer in systemic sclerosis.

Autoimmun Rev 2017 08 29;16(8):883-884. Epub 2017 May 29.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.autrev.2017.05.023DOI Listing
August 2017

Genomic Influences on Susceptibility and Severity of Rheumatoid Arthritis.

Rheum Dis Clin North Am 2017 08;43(3):347-361

Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.rdc.2017.04.002DOI Listing
August 2017

Ten years of METEOR (an international rheumatoid arthritis registry): development, research opportunities and future perspectives.

Clin Exp Rheumatol 2016 Sep-Oct;34(5 Suppl 101):S87-S90. Epub 2016 Oct 19.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

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February 2017

TAC-TIC use of tacrolimus-based regimens in lupus nephritis.

Lupus Sci Med 2016 29;3(1):e000169. Epub 2016 Dec 29.

Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands; Clinic for Lupus-, Vasculitis and Complement-Mediated Systemic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/lupus-2016-000169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237713PMC
December 2016

The production and secretion of complement component C1q by human mast cells.

Mol Immunol 2016 10 17;78:164-170. Epub 2016 Sep 17.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2016.09.001DOI Listing
October 2016

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 10 10;7:13205. Epub 2016 Oct 10.

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http://dx.doi.org/10.1038/ncomms13205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062501PMC
October 2016

Repeated FcεRI triggering reveals modified mast cell function related to chronic allergic responses in tissue.

J Allergy Clin Immunol 2016 09 28;138(3):869-880. Epub 2016 Mar 28.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.01.017DOI Listing
September 2016

Sustained improvements in MRI outcomes with abatacept following the withdrawal of all treatments in patients with early, progressive rheumatoid arthritis.

Ann Rheum Dis 2016 Aug 10;75(8):1501-5. Epub 2016 Feb 10.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-208258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975847PMC
August 2016

Validity and responsiveness of the Michigan Hand Questionnaire in patients with systemic sclerosis.

Rheumatology (Oxford) 2016 08 12;55(8):1386-93. Epub 2016 Apr 12.

Department of Rheumatology, Leiden University Medical Center, Department of Orthopaedics, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kew016DOI Listing
August 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 08 23;7:12460. Epub 2016 Aug 23.

Sage Bionetworks, Seattle, Washington 98115, USA.

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http://dx.doi.org/10.1038/ncomms12460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996969PMC
August 2016

Drivers of costly treatment strategies in rheumatoid arthritis.

Lancet 2016 Jul 17;388(10041):213-4. Epub 2016 May 17.

Department of Rheumatology, Landspítali, National University Hospital, Center for Rheumatology Research, Reykjavík, Iceland.

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http://dx.doi.org/10.1016/S0140-6736(16)30548-7DOI Listing
July 2016

Human mast cells costimulate T cells through a CD28-independent interaction.

Eur J Immunol 2016 05 11;46(5):1132-41. Epub 2016 Mar 11.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/eji.201545914DOI Listing
May 2016

The role of anticitrullinated protein antibodies in the early stages of rheumatoid arthritis.

Curr Opin Rheumatol 2016 May;28(3):275-81

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/BOR.0000000000000277DOI Listing
May 2016

Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites.

Brain 2016 05 11;139(Pt 5):1447-57. Epub 2016 Mar 11.

C. J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

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http://dx.doi.org/10.1093/brain/aww031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006250PMC
May 2016

A prediction model for progressive disease in systemic sclerosis.

RMD Open 2015 1;1(1):e000113. Epub 2015 Dec 1.

Department of Rheumatology , Leiden University Medical Center , Leiden , The Netherlands.

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http://dx.doi.org/10.1136/rmdopen-2015-000113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680735PMC
December 2015

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.

Arthritis Res Ther 2015 Nov 24;17:339. Epub 2015 Nov 24.

Department of Rheumatology, Leiden University Medical Center, C1-R, LUMC, PO Box 9600, 2300, RC Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s13075-015-0860-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657226PMC
November 2015

Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent.

Rheumatology (Oxford) 2015 Oct 15;54(10):1930-2. Epub 2015 Jul 15.

Department of Medicine, Rheumatic Diseases Unit, Kyushu University Beppu Hospital, Beppu, Japan.

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http://dx.doi.org/10.1093/rheumatology/kev250DOI Listing
October 2015

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.

Authors:
S Hong Lee Enda M Byrne Christina M Hultman Anna Kähler Anna A E Vinkhuyzen Stephan Ripke Ole A Andreassen Thomas Frisell Alexander Gusev Xinli Hu Robert Karlsson Vasilis X Mantzioris John J McGrath Divya Mehta Eli A Stahl Qiongyi Zhao Kenneth S Kendler Patrick F Sullivan Alkes L Price Michael O'Donovan Yukinori Okada Bryan J Mowry Soumya Raychaudhuri Naomi R Wray William Byerley Wiepke Cahn Rita M Cantor Sven Cichon Paul Cormican David Curtis Srdjan Djurovic Valentina Escott-Price Pablo V Gejman Lyudmila Georgieva Ina Giegling Thomas F Hansen Andrés Ingason Yunjung Kim Bettina Konte Phil H Lee Andrew McIntosh Andrew McQuillin Derek W Morris Markus M Nöthen Colm O'Dushlaine Ann Olincy Line Olsen Carlos N Pato Michele T Pato Benjamin S Pickard Danielle Posthuma Henrik B Rasmussen Marcella Rietschel Dan Rujescu Thomas G Schulze Jeremy M Silverman Srinivasa Thirumalai Thomas Werge Ingrid Agartz Farooq Amin Maria H Azevedo Nicholas Bass Donald W Black Douglas H R Blackwood Richard Bruggeman Nancy G Buccola Khalid Choudhury Robert C Cloninger Aiden Corvin Nicholas Craddock Mark J Daly Susmita Datta Gary J Donohoe Jubao Duan Frank Dudbridge Ayman Fanous Robert Freedman Nelson B Freimer Marion Friedl Michael Gill Hugh Gurling Lieuwe De Haan Marian L Hamshere Annette M Hartmann Peter A Holmans René S Kahn Matthew C Keller Elaine Kenny George K Kirov Lydia Krabbendam Robert Krasucki Jacob Lawrence Todd Lencz Douglas F Levinson Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Patrik K E Magnusson Wolfgang Maier Anil K Malhotra Manuel Mattheisen Morten Mattingsdal Steven A McCarroll Helena Medeiros Ingrid Melle Vihra Milanova Inez Myin-Germeys Benjamin M Neale Roel A Ophoff Michael J Owen Jonathan Pimm Shaun M Purcell Vinay Puri Digby J Quested Lizzy Rossin Douglas Ruderfer Alan R Sanders Jianxin Shi Pamela Sklar David St Clair T Scott Stroup Jim Van Os Peter M Visscher Durk Wiersma Stanley Zammit S Louis Bridges Hyon K Choi Marieke J H Coenen Niek de Vries Philippe Dieud Jeffrey D Greenberg Tom W J Huizinga Leonid Padyukov Katherine A Siminovitch Paul P Tak Jane Worthington Philip L De Jager Joshua C Denny Peter K Gregersen Lars Klareskog Xavier Mariette Robert M Plenge Mart van Laar Piet van Riel

Int J Epidemiol 2015 Oct;44(5):1706-21

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http://dx.doi.org/10.1093/ije/dyv136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881824PMC
October 2015

Fatigue in rheumatoid arthritis; a persistent problem: a large longitudinal study.

RMD Open 2015 4;1(1):e000041. Epub 2015 Mar 4.

Department of Rheumatology , Leiden University Medical Center , Leiden , The Netherlands.

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http://dx.doi.org/10.1136/rmdopen-2014-000041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612698PMC
October 2015

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.

Arthritis Res Ther 2015 Aug 24;17:209. Epub 2015 Aug 24.

Department of Rheumatology, Leiden University Medical Centre, C1-R, PO Box 9600, 2300, RC, Leiden, the Netherlands.

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http://dx.doi.org/10.1186/s13075-015-0665-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548712PMC
August 2015

Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.

Arthritis Res Ther 2015 Aug 20;17:220. Epub 2015 Aug 20.

Department of Rheumatology, Leiden University Medical Centre, PO Box 9600, 2300, RC, Leiden, the Netherlands.

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http://dx.doi.org/10.1186/s13075-015-0731-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545927PMC
August 2015

Response to 'Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis'--authors' reply.

Arthritis Res Ther 2015 Jul 2;17:171. Epub 2015 Jul 2.

Department of Rheumatology, Leiden University Medical Center, C-01-R, PO BOX 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s13075-015-0681-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488129PMC
July 2015