Publications by authors named "Tom W J Huizinga"

100Publications

Evolution of interstitial lung disease one year after hematopoietic stem cell transplantation or cyclophosphamide for systemic sclerosis.

Arthritis Care Res (Hoboken) 2020 Sep 22. Epub 2020 Sep 22.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/acr.24451DOI Listing
September 2020

Interpreting big-data analysis of retrospective observational data.

Lancet Rheumatol 2020 Aug 21. Epub 2020 Aug 21.

Department or Rheumatology, Leiden University Medical Center, Leiden, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2665-9913(20)30289-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442429PMC
August 2020

Association between centromere and topoisomerase specific immune responses and the degree of microangiopathy in Systemic Sclerosis.

J Rheumatol 2020 Jun 1. Epub 2020 Jun 1.

From the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, the Netherlands. Address correspondence to Nina M. van Leeuwen, department of Rheumatology Leiden University Medical Center, C1-R, PO Box 9600, 2300 RC, Leiden, the Netherlands. E-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.191331DOI Listing
June 2020

Increasing incidence of autoantibody-negative RA is replicated and is partly explained by an aging population.

Ann Rheum Dis 2020 May 29. Epub 2020 May 29.

Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2020-217609DOI Listing
May 2020

Smoking and systemic sclerosis: influence on microangiopathy and expression of anti-topoisomerase I antibodies in a monocentric cohort.

Clin Exp Rheumatol 2020 May-Jun;38 Suppl 125(3):25-28. Epub 2020 Mar 25.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
September 2020

One year in review 2020: novelties in the treatment of rheumatoid arthritis.

Clin Exp Rheumatol 2020 Mar-Apr;38(2):181-194. Epub 2020 Mar 26.

Department of Rheumatology, Leiden University Medical Centre, The Netherlands.

View Article

Download full-text PDF

Source
April 2020

Illness perceptions, risk perceptions and worries in patients with early systemic sclerosis: A focus group study.

Musculoskeletal Care 2020 Jun 26;18(2):177-186. Epub 2020 Jan 26.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/msc.1453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318332PMC
June 2020

Lung function is associated with minimal EQ-5D changes over time in patients with systemic sclerosis.

Clin Rheumatol 2020 May 24;39(5):1543-1549. Epub 2020 Jan 24.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10067-020-04951-6DOI Listing
May 2020

The contribution of sex and auto-antibodies to microangiopathy assessed by nailfold videocapillaroscopy in systemic sclerosis: a systematic review of the literature.

Arthritis Care Res (Hoboken) 2020 Jan 21. Epub 2020 Jan 21.

Leiden University Medical Center, department of Rheumatology, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/acr.24149DOI Listing
January 2020

An overview of autoantibodies in rheumatoid arthritis.

J Autoimmun 2020 Jun 3;110:102392. Epub 2020 Jan 3.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2019.102392DOI Listing
June 2020

Pharmacological conditioning in the treatment of recent-onset rheumatoid arthritis: a randomized controlled trial study protocol.

Trials 2020 Jan 6;21(1):15. Epub 2020 Jan 6.

Faculty of Social and Behavioural Sciences, Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, P.O. Box 9555, 2300 RB, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-019-3777-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945543PMC
January 2020

Cumulative endogenous estrogen exposure is not associated with severity of peripheral microangiopathy in patients with systemic sclerosis.

Clin Exp Rheumatol 2019 Jul-Aug;37 Suppl 119(4):82-87. Epub 2019 Oct 3.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
October 2019

Shrinking Lung Syndrome: Diagnostic and Therapeutic Challenges in 3 Patients With Systemic Lupus Erythematosus.

J Clin Rheumatol 2019 Sep 2. Epub 2019 Sep 2.

Department of Rheumatology Leiden University Medical Center Leiden, the Netherlands Rheumatology Unit Azienda Policlinico of Modena University of Modena and Reggio Emilia Modena, Italy. Medicine and Rheumatology Unit IRCCS Istituto Ortopedico Rizzoli Bologna, Italy Department of Rheumatology Leiden University Medical Center Leiden, the Netherlands. Department of Pulmonology Leiden University Medical Center Leiden, the Netherlands. Department of Rheumatology Leiden University Medical Center Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RHU.0000000000001132DOI Listing
September 2019

Sex hormones and sex hormone-targeting therapies in systemic sclerosis: A systematic literature review.

Semin Arthritis Rheum 2020 02 20;50(1):140-148. Epub 2019 Jul 20.

Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semarthrit.2019.07.007DOI Listing
February 2020

Treat-to-Target Strategies in Rheumatoid Arthritis.

JAMA 2019 07;322(1):83

Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2019.5848DOI Listing
July 2019

Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening.

J Rheumatol 2019 Sep 1;46(9):1244-1245. Epub 2019 Jul 1.

Leiden University Medical Center, Department of Rheumatology, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.181378DOI Listing
September 2019

Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study.

J Rheumatol 2019 04 1;46(4):405-415. Epub 2019 Mar 1.

From the Department of Cardiology, Heart Lung Center, and the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.171207DOI Listing
April 2019

Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria.

Rheumatology (Oxford) 2019 04;58(4):730-732

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kez005DOI Listing
April 2019

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

Cancer Immunol Res 2019 01 13;7(1):6-11. Epub 2018 Nov 13.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://cancerimmunolres.aacrjournals.org/lookup/doi/10.1158/
Publisher Site
http://dx.doi.org/10.1158/2326-6066.CIR-18-0245DOI Listing
January 2019

On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis.

Rheumatol Int 2018 12 20;38(12):2225-2231. Epub 2018 Oct 20.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00296-018-4173-3
Publisher Site
http://dx.doi.org/10.1007/s00296-018-4173-3DOI Listing
December 2018

To what extent do autoantibodies help to identify high-risk patients in systemic sclerosis?

Clin Exp Rheumatol 2018 Jul-Aug;36 Suppl 113(4):109-117. Epub 2018 Jul 18.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
January 2019

MR signal intensity: staying on the bright side in MR image interpretation.

RMD Open 2018 20;4(1):e000728. Epub 2018 Jun 20.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/rmdopen-2018-000728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018882PMC
June 2018

The B cell response to citrullinated antigens in the development of rheumatoid arthritis.

Nat Rev Rheumatol 2018 03 8;14(3):157-169. Epub 2018 Feb 8.

Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/nrrheum.2018.10
Publisher Site
http://dx.doi.org/10.1038/nrrheum.2018.10DOI Listing
March 2018

Depression and anxiety associate with less remission after 1 year in rheumatoid arthritis.

Ann Rheum Dis 2019 01 8;78(1):e1. Epub 2018 Jan 8.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2017-212867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314454PMC
January 2019

An evidence-based approach to pre-pregnancy counselling for patients with systemic lupus erythematosus.

Rheumatology (Oxford) 2018 10;57(10):1707-1720

Department of Gynaecology and Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kex374DOI Listing
October 2018

Preventing progression from arthralgia to arthritis: targeting the right patients.

Nat Rev Rheumatol 2018 Jan 9;14(1):32-41. Epub 2017 Nov 9.

Department of Rheumatology, Leiden University Medical Centre, C4-R, PO Box 9600, Leiden, RC 2300, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrrheum.2017.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298577PMC
January 2018

Rheumatoid arthritis patients with continued low disease activity have similar outcomes over 10 years, regardless of initial therapy.

Rheumatology (Oxford) 2017 10;56(10):1721-1728

Department of Rheumatology, Leiden University Medical Center, Leiden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kex236DOI Listing
October 2017

Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort.

J Rheumatol 2017 Nov 15;44(11):1659-1666. Epub 2017 Sep 15.

From the departments of Rheumatology, Radiology, and Clinical Epidemiology, Leiden University Medical Center (LUMC), Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.170208DOI Listing
November 2017

Genomic Influences on Susceptibility and Severity of Rheumatoid Arthritis.

Rheum Dis Clin North Am 2017 08;43(3):347-361

Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rdc.2017.04.002DOI Listing
August 2017

Auto-antibodies and cancer in systemic sclerosis.

Autoimmun Rev 2017 08 29;16(8):883-884. Epub 2017 May 29.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.autrev.2017.05.023DOI Listing
August 2017

Is optimising gout treatment the key to closing the mortality gap in gout patients?

Ann Rheum Dis 2018 01 25;77(1):e2. Epub 2017 May 25.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2017-211638DOI Listing
January 2018

Dosing down with biologic therapies: a systematic review and clinicians' perspective.

Rheumatology (Oxford) 2017 11;56(11):1847-1856

Department of Rheumatology, Leiden University Medical Center, Leiden, C1-41, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kew464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850865PMC
November 2017

TAC-TIC use of tacrolimus-based regimens in lupus nephritis.

Lupus Sci Med 2016 29;3(1):e000169. Epub 2016 Dec 29.

Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands; Clinic for Lupus-, Vasculitis and Complement-Mediated Systemic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/lupus-2016-000169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237713PMC
December 2016

Ten years of METEOR (an international rheumatoid arthritis registry): development, research opportunities and future perspectives.

Clin Exp Rheumatol 2016 Sep-Oct;34(5 Suppl 101):S87-S90. Epub 2016 Oct 19.

Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
February 2017

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 10 10;7:13205. Epub 2016 Oct 10.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms13205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062501PMC
October 2016

The production and secretion of complement component C1q by human mast cells.

Mol Immunol 2016 10 17;78:164-170. Epub 2016 Sep 17.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2016.09.001DOI Listing
October 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 08 23;7:12460. Epub 2016 Aug 23.

Sage Bionetworks, Seattle, Washington 98115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms12460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996969PMC
August 2016

Drivers of costly treatment strategies in rheumatoid arthritis.

Lancet 2016 Jul 17;388(10041):213-4. Epub 2016 May 17.

Department of Rheumatology, Landspítali, National University Hospital, Center for Rheumatology Research, Reykjavík, Iceland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(16)30548-7DOI Listing
July 2016

Validity and responsiveness of the Michigan Hand Questionnaire in patients with systemic sclerosis.

Rheumatology (Oxford) 2016 08 12;55(8):1386-93. Epub 2016 Apr 12.

Department of Rheumatology, Leiden University Medical Center, Department of Orthopaedics, Leiden University Medical Center, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kew016DOI Listing
August 2016

Repeated FcεRI triggering reveals modified mast cell function related to chronic allergic responses in tissue.

J Allergy Clin Immunol 2016 09 28;138(3):869-880. Epub 2016 Mar 28.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.01.017DOI Listing
September 2016

Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites.

Brain 2016 05 11;139(Pt 5):1447-57. Epub 2016 Mar 11.

C. J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/aww031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006250PMC
May 2016

The role of anticitrullinated protein antibodies in the early stages of rheumatoid arthritis.

Curr Opin Rheumatol 2016 May;28(3):275-81

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BOR.0000000000000277DOI Listing
May 2016